This is a Validated Antibody Database (VAD) review about human PTGS2, based on 124 published articles (read how Labome selects the articles), using PTGS2 antibody in all methods. It is aimed to help Labome visitors find the most suited PTGS2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
PTGS2 synonym: COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2

Knockout validation
Abcam
domestic rabbit polyclonal
  • immunohistochemistry knockout validation; mouse; 1:100; loading ...; fig 5b
  • western blot; mouse; loading ...; fig 4c
Abcam PTGS2 antibody (Abcam, ab15191) was used in immunohistochemistry knockout validation on mouse samples at 1:100 (fig 5b) and in western blot on mouse samples (fig 4c). Bone Res (2019) ncbi
Invitrogen
domestic rabbit monoclonal (SP21)
  • western blot; human; fig 1a
Invitrogen PTGS2 antibody (Thermo Scientific, RM-9121-R7) was used in western blot on human samples (fig 1a). NPJ Breast Cancer (2020) ncbi
domestic rabbit monoclonal (SP21)
  • western blot; rat; 1:2000; loading ...; fig 8
Invitrogen PTGS2 antibody (Thermo Scientific, MA5-14568) was used in western blot on rat samples at 1:2000 (fig 8). BMC Cancer (2019) ncbi
domestic rabbit monoclonal (SP21)
  • western blot; mouse; 1:2000; loading ...; fig 4f
In order to assess the role of microglial cells in diabetic retinopathy, Invitrogen PTGS2 antibody (Invitrogen, MA5-14568) was used in western blot on mouse samples at 1:2000 (fig 4f). J Mol Neurosci (2017) ncbi
domestic rabbit monoclonal (SP21)
  • immunohistochemistry - paraffin section; dogs; 1:1500; loading ...; fig 1c
In order to measure renal cyclooxygenase-1 and -2 expression in dogs with chronic kidney disease, Invitrogen PTGS2 antibody (Thermo Scientific, SP21) was used in immunohistochemistry - paraffin section on dogs samples at 1:1500 (fig 1c). Res Vet Sci (2016) ncbi
domestic rabbit monoclonal (SP21)
  • immunohistochemistry; dogs; loading ...; fig 2b
In order to evaluate the addition of COX-2 expression and mitotic index for the identification of canine renal cell carcinoma, Invitrogen PTGS2 antibody (ThermoFisher Scientific, SP-21) was used in immunohistochemistry on dogs samples (fig 2b). Vet Comp Oncol (2017) ncbi
domestic rabbit monoclonal (SP21)
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 1
In order to identify prognostic biomarkers for gastric cancer, Invitrogen PTGS2 antibody (Thermo Scientific, SP2) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 1). J Egypt Natl Canc Inst (2016) ncbi
domestic rabbit monoclonal (SP21)
In order to test if 5-hydroxytryptophan or 5-methoxytryptophan can prevent collagen-induced arthritis, Invitrogen PTGS2 antibody (Thermo Scientific, SP21) was used . Arthritis Res Ther (2015) ncbi
mouse monoclonal (COX 229)
  • immunohistochemistry; mouse
In order to examine Cox-2 expression in epithelial and stromal cells in breast cancer samples, Invitrogen PTGS2 antibody (Invitrogen, 35-8200) was used in immunohistochemistry on mouse samples . Breast Cancer Res Treat (2015) ncbi
domestic rabbit monoclonal (SP21)
  • immunohistochemistry - paraffin section; human; 1:50
In order to identify master regulators of inflammatory breast cancer, Invitrogen PTGS2 antibody (Thermo LABVISION, RM-9121-S0) was used in immunohistochemistry - paraffin section on human samples at 1:50. J Transl Med (2015) ncbi
domestic rabbit monoclonal (SP21)
  • immunohistochemistry - paraffin section; domestic goat; 1:20
Invitrogen PTGS2 antibody (Lab Vision, SP21) was used in immunohistochemistry - paraffin section on domestic goat samples at 1:20. Vet J (2015) ncbi
domestic rabbit monoclonal (SP21)
  • immunohistochemistry - paraffin section; cat; 1:75
Invitrogen PTGS2 antibody (Neomarkers & LabVision Corporation, SP21) was used in immunohistochemistry - paraffin section on cat samples at 1:75. Reprod Domest Anim (2015) ncbi
mouse monoclonal (COX 229)
  • western blot; human; 1:1000; fig 4
In order to demonstrate that emodin attenuates LPS- and hypoxia/reoxygenation-induced intestinal epithelial barrier dysfunction by inhibiting the HIF-1alpha and NF-kappaB signaling pathways, which regulate tight junctions, Invitrogen PTGS2 antibody (BD Biosciences, 35-8200) was used in western blot on human samples at 1:1000 (fig 4). Int J Mol Med (2014) ncbi
domestic rabbit monoclonal (SP21)
  • immunohistochemistry; human
In order to discuss the relevance of COX-2 expression in breast cancer, Invitrogen PTGS2 antibody (Thermo Fisher Scientific, RM-1921) was used in immunohistochemistry on human samples . BMC Cancer (2014) ncbi
mouse monoclonal (COX 229)
  • western blot; human; 1:1000
In order to study COX-2 overexpression and polymorphism in non-small cell lung cancer, Invitrogen PTGS2 antibody (Invitrogen, 35-8200) was used in western blot on human samples at 1:1000. Tumour Biol (2014) ncbi
domestic rabbit monoclonal (SP21)
  • immunohistochemistry - paraffin section; mouse; 1:50; fig 5
In order to determine how loss of Trp53 and Cdh1 in the uterus can induce chronic inflammation with a change in the tumor microenvironment, Invitrogen PTGS2 antibody (Thermo Scientific, RM-9121) was used in immunohistochemistry - paraffin section on mouse samples at 1:50 (fig 5). Oncogene (2015) ncbi
domestic rabbit monoclonal (SP21)
  • immunohistochemistry; rat; 1:100; fig 1, 2, 3
In order to study the effect of artificial food colors and additives on laryngeal histomorphology and immunohistochemical expression in maternally exposed rats, Invitrogen PTGS2 antibody (Thermo Scientific, SP21) was used in immunohistochemistry on rat samples at 1:100 (fig 1, 2, 3). J Environ Pathol Toxicol Oncol (2014) ncbi
domestic rabbit monoclonal (SP21)
  • immunohistochemistry; human
Invitrogen PTGS2 antibody (Thermo, sp21) was used in immunohistochemistry on human samples . BMC Cancer (2014) ncbi
mouse monoclonal (COX 229)
  • western blot; human; fig 3
In order to study the localization of a GRSF1 isoform to the mitochondrial matrix and its role in RNA processing, Invitrogen PTGS2 antibody (Invitrogen, 35-8200) was used in western blot on human samples (fig 3). Cell Metab (2013) ncbi
mouse monoclonal (COX 229)
  • immunohistochemistry - paraffin section; human; 1:100; fig 1
In order to study the relationship between cyclooxygenase enzymes and E-cadherin in the prediction of survival in optimally cytoreduced serous ovarian cancer patients, Invitrogen PTGS2 antibody (Zymed, Cox229) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 1). Asian Pac J Cancer Prev (2012) ncbi
domestic rabbit monoclonal (SP21)
  • immunohistochemistry; human; fig s1
In order to determine the prognostic potential of COX2 expression in urothelial carcinoma of the bladder, Invitrogen PTGS2 antibody (ThermoFisher Scientific, RM-9121-R7) was used in immunohistochemistry on human samples (fig s1). PLoS ONE (2012) ncbi
domestic rabbit monoclonal (SP21)
  • immunohistochemistry - paraffin section; rat; fig 1
In order to perform an immunohistochemical study and early degenerative effects of diabetes mellitus on liver, kidney and pancreas in rats, Invitrogen PTGS2 antibody (Thermo scientific, RM-9121-S0) was used in immunohistochemistry - paraffin section on rat samples (fig 1). Exp Diabetes Res (2012) ncbi
domestic rabbit monoclonal (SP21)
  • immunohistochemistry - paraffin section; pigs ; fig 1
In order to study neuronal Cox-2 expression in different regions of the newborn pig brain, Invitrogen PTGS2 antibody (Labvision, SP21) was used in immunohistochemistry - paraffin section on pigs samples (fig 1). Acta Histochem Cytochem (2012) ncbi
mouse monoclonal (COX 229)
  • immunocytochemistry; human; fig 4
In order to discuss pollutants as contributors to asthma, Invitrogen PTGS2 antibody (Invitrogen, 35-8200) was used in immunocytochemistry on human samples (fig 4). PLoS ONE (2011) ncbi
mouse monoclonal (COX 229)
  • immunohistochemistry - paraffin section; human; tbl 2
  • immunocytochemistry; human; tbl 1
In order to investigate mechanisms that up-regulate COX-2 with VEGF in non-small cell lung cancer, Invitrogen PTGS2 antibody (Invitrogen, clone COX 229) was used in immunohistochemistry - paraffin section on human samples (tbl 2) and in immunocytochemistry on human samples (tbl 1). J Exp Clin Cancer Res (2011) ncbi
mouse monoclonal (COX 229)
  • immunohistochemistry - paraffin section; human; 1:50; fig 3
In order to study the interactions between prostate cancer cells and osteoblasts, Invitrogen PTGS2 antibody (Invitrogen, COX 229) was used in immunohistochemistry - paraffin section on human samples at 1:50 (fig 3). Br J Cancer (2011) ncbi
mouse monoclonal (COX 229)
  • immunohistochemistry - paraffin section; human; fig 3
In order to report the first systematic analysis of spatio-temporal protein networks driving the many stages of heart development, Invitrogen PTGS2 antibody (Invitrogen, 35-8200) was used in immunohistochemistry - paraffin section on human samples (fig 3). Mol Syst Biol (2010) ncbi
domestic rabbit monoclonal (SP21)
  • immunohistochemistry - paraffin section; human; 1:800; fig 1
In order to identify immunohistochemical markers to aid chondroid tumor diagnosis, Invitrogen PTGS2 antibody (Neomarkers, SP21) was used in immunohistochemistry - paraffin section on human samples at 1:800 (fig 1). APMIS (2009) ncbi
domestic rabbit monoclonal (SP21)
  • immunohistochemistry - paraffin section; human; 1:75; tbl 2
In order to characterize feline endometrial adenocarcinomas immunohistochemically, Invitrogen PTGS2 antibody (Neomarkers, SP21) was used in immunohistochemistry - paraffin section on human samples at 1:75 (tbl 2). J Comp Pathol (2009) ncbi
mouse monoclonal (COX 229)
  • immunohistochemistry - paraffin section; human; 1:400
In order to study the expression of cyclooxygenase-2 in human choroidal neovascular membranes, Invitrogen PTGS2 antibody (Zymed Laboratories, COX 229) was used in immunohistochemistry - paraffin section on human samples at 1:400. Retina (2009) ncbi
mouse monoclonal (COX 229)
  • immunohistochemistry - paraffin section; human; 1:50; fig 1
In order to test if COX-2 is a prognostic factor in glottic cancer, Invitrogen PTGS2 antibody (Zymed Laboratories, COX 229) was used in immunohistochemistry - paraffin section on human samples at 1:50 (fig 1). Clin Cancer Res (2008) ncbi
mouse monoclonal (COX 229)
  • immunohistochemistry - paraffin section; human; 1:50; tbl 1
In order to determine the expression of PAR-1, PAR-2, MMP-2, MMP-9, COX-1, and COX-2 in patients with orofacial granulomatosis, Invitrogen PTGS2 antibody (Zymed, COX 229) was used in immunohistochemistry - paraffin section on human samples at 1:50 (tbl 1). Oral Dis (2007) ncbi
mouse monoclonal (COX 229)
  • immunohistochemistry - paraffin section; human; fig 2
In order to study cyclooxygenase-2 expression in meningiomas, Invitrogen PTGS2 antibody (Zymed, COX 229) was used in immunohistochemistry - paraffin section on human samples (fig 2). Appl Immunohistochem Mol Morphol (2007) ncbi
mouse monoclonal (COX 229)
  • immunohistochemistry - paraffin section; human; 1:50; fig 1
In order to investigate the role of COX-2 expression in tumor-associated macrophages from melanoma, Invitrogen PTGS2 antibody (Zymed, COX-229) was used in immunohistochemistry - paraffin section on human samples at 1:50 (fig 1). Prostaglandins Other Lipid Mediat (2007) ncbi
mouse monoclonal (COX 229)
  • immunohistochemistry - paraffin section; domestic rabbit; 1:500
In order to assess the efficiency of Nepafenac, a topically administered COX-2 inhibitor, in a rabbit model of uveal melanoma, Invitrogen PTGS2 antibody (Zymed, COX 229) was used in immunohistochemistry - paraffin section on domestic rabbit samples at 1:500. Carcinogenesis (2007) ncbi
mouse monoclonal (COX 229)
  • immunohistochemistry - paraffin section; human; 1:100
In order to investigate the effect of COX-2 and iNOS on tumor progression, Invitrogen PTGS2 antibody (Zymed, COX 229) was used in immunohistochemistry - paraffin section on human samples at 1:100. J Korean Med Sci (2006) ncbi
mouse monoclonal (COX 229)
  • immunohistochemistry - paraffin section; human; 1:50; fig 1
In order to examine the relationship between cyclooxygenase-2 expression and histopathologic features of retinoblastoma specimens treated either by primary or secondary enucleation, Invitrogen PTGS2 antibody (Zymed, COX 229) was used in immunohistochemistry - paraffin section on human samples at 1:50 (fig 1). Am J Ophthalmol (2006) ncbi
mouse monoclonal (COX 229)
  • immunohistochemistry - paraffin section; rat; 1:100; fig 2
In order to test if Cryptosporidium-induced changes in the lungs are mediated through the activation of COX-2 and NF-kB, Invitrogen PTGS2 antibody (Zymed, COX 229) was used in immunohistochemistry - paraffin section on rat samples at 1:100 (fig 2). APMIS (2006) ncbi
mouse monoclonal (COX 229)
  • immunohistochemistry - paraffin section; human
In order to study COX-2 receptor expression in primary childhood brain tumors, Invitrogen PTGS2 antibody (Zymed, 35-8200) was used in immunohistochemistry - paraffin section on human samples . In Vivo (2006) ncbi
Abcam
domestic rabbit monoclonal (EPR12012)
  • western blot; human; 1:1000; fig 4a, 6a
Abcam PTGS2 antibody (Abcam, ab179800) was used in western blot on human samples at 1:1000 (fig 4a, 6a). elife (2022) ncbi
domestic rabbit monoclonal (EPR12012)
  • western blot; human; loading ...; fig 7d
Abcam PTGS2 antibody (Abcam, ab179800) was used in western blot on human samples (fig 7d). Front Endocrinol (Lausanne) (2022) ncbi
domestic rabbit polyclonal
  • western blot; rat; loading ...
Abcam PTGS2 antibody (Abcam, ab15191) was used in western blot on rat samples . Redox Biol (2022) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 5a
Abcam PTGS2 antibody (Abcam, ab15191) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig 5a). Proc Natl Acad Sci U S A (2022) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; fig 3
Abcam PTGS2 antibody (abcam, ab15191) was used in immunohistochemistry on mouse samples (fig 3). JOR Spine (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; human; loading ...; fig 1a, 1b
Abcam PTGS2 antibody (Abcam, ab15191) was used in immunohistochemistry on human samples (fig 1a, 1b). PLoS ONE (2021) ncbi
domestic rabbit monoclonal (EPR12012)
  • western blot; mouse; 1:1000; loading ...; fig 3
Abcam PTGS2 antibody (Abcam, ab179800) was used in western blot on mouse samples at 1:1000 (fig 3). J Orthop Surg Res (2021) ncbi
domestic rabbit monoclonal (EPR12012)
  • western blot; mouse; 1:1000; loading ...; fig 6a
Abcam PTGS2 antibody (Abcam, ab179800) was used in western blot on mouse samples at 1:1000 (fig 6a). Front Pharmacol (2021) ncbi
domestic rabbit monoclonal (EPR12012)
  • western blot; rat; loading ...; fig 6a
Abcam PTGS2 antibody (Abcam, ab179800) was used in western blot on rat samples (fig 6a). Front Endocrinol (Lausanne) (2021) ncbi
domestic rabbit monoclonal (EPR12012)
  • western blot; human; 1:5000; loading ...; fig 5c, 7e
Abcam PTGS2 antibody (Abcam, ab179800) was used in western blot on human samples at 1:5000 (fig 5c, 7e). Redox Biol (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 2a
Abcam PTGS2 antibody (Abcam, ab15191) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 2a). elife (2020) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; human; 1 ug/ml; loading ...
Abcam PTGS2 antibody (Abcam, 15191) was used in immunohistochemistry on human samples at 1 ug/ml. Arterioscler Thromb Vasc Biol (2020) ncbi
domestic goat polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 2d, 5d
Abcam PTGS2 antibody (Abcam, 23672) was used in western blot on mouse samples at 1:1000 (fig 2d, 5d). Front Neurosci (2020) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 3d
Abcam PTGS2 antibody (Abcam, Ab15191) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig 3d). elife (2020) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 6c
Abcam PTGS2 antibody (Abcam, ab15191) was used in immunohistochemistry - paraffin section on mouse samples (fig 6c). Dev Cell (2019) ncbi
domestic rabbit monoclonal (EPR12012)
  • western blot; human; loading ...; fig 4b
Abcam PTGS2 antibody (Abcam, ab179800) was used in western blot on human samples (fig 4b). PLoS ONE (2019) ncbi
domestic rabbit polyclonal
  • immunohistochemistry knockout validation; mouse; 1:100; loading ...; fig 5b
  • western blot; mouse; loading ...; fig 4c
Abcam PTGS2 antibody (Abcam, ab15191) was used in immunohistochemistry knockout validation on mouse samples at 1:100 (fig 5b) and in western blot on mouse samples (fig 4c). Bone Res (2019) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 1f
Abcam PTGS2 antibody (Abcam, ab15191) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig 1f). Cancer Cell Int (2019) ncbi
domestic rabbit monoclonal (EPR12012)
  • western blot; human; loading ...; fig 4b
Abcam PTGS2 antibody (Abcam, ab179800) was used in western blot on human samples (fig 4b). Biosci Rep (2019) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:100; loading ...; fig 5c
Abcam PTGS2 antibody (Abcam, ab15191) was used in immunohistochemistry on mouse samples at 1:100 (fig 5c). Nat Commun (2019) ncbi
domestic rabbit monoclonal (EP1978Y)
  • western blot; human; loading ...; fig 4i
Abcam PTGS2 antibody (Abcam, ab62331) was used in western blot on human samples (fig 4i). Cancers (Basel) (2018) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; rat; 1:100; fig 7g
Abcam PTGS2 antibody (Abcam, ab52237) was used in immunohistochemistry - frozen section on rat samples at 1:100 (fig 7g). J Neuroinflammation (2018) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 7a
  • western blot; mouse; fig 5a
Abcam PTGS2 antibody (Abcam, ab15191) was used in western blot on human samples (fig 7a) and in western blot on mouse samples (fig 5a). J Biol Chem (2018) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 3c
In order to assess the effects of hypoxia on cellular senescence and the immunomodulatory abilities of hUCB-mesenchymal stem cells, Abcam PTGS2 antibody (Abcam, ab15191) was used in western blot on human samples at 1:1000 (fig 3c). Aging (Albany NY) (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:200; fig 5c
Abcam PTGS2 antibody (Abcam, ab15191) was used in western blot on human samples at 1:200 (fig 5c). Arthritis Res Ther (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 4
In order to assess the mediation of EGF-stimulated expression of the prostaglandin synthase COX2 and prostaglandin release in human myometrium via the steroid receptor co-activator interacting protein (SIP), Abcam PTGS2 antibody (Abcam, ab52237) was used in western blot on human samples (fig 4). Mol Hum Reprod (2016) ncbi
domestic rabbit monoclonal (SP21)
  • immunohistochemistry; human; 1:100; fig 1
Abcam PTGS2 antibody (Abcam, ab16701) was used in immunohistochemistry on human samples at 1:100 (fig 1). Arch Med Sci (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 5
Abcam PTGS2 antibody (Abcam, ab15191) was used in western blot on human samples (fig 5). BMC Complement Altern Med (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:100; fig 4
Abcam PTGS2 antibody (Abcam, ab15191) was used in immunohistochemistry on mouse samples at 1:100 (fig 4). PLoS ONE (2016) ncbi
domestic rabbit monoclonal (EP1978Y)
  • immunocytochemistry; human; fig 2f
  • western blot; human; fig 2f
Abcam PTGS2 antibody (Abcam, ab62331) was used in immunocytochemistry on human samples (fig 2f) and in western blot on human samples (fig 2f). Arthritis Res Ther (2015) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; fig 8
In order to characterize linalool that reverses behavioral and neuropathological impairments in old triple transgenic Alzheimer's mice, Abcam PTGS2 antibody (Abcam, AB15191) was used in western blot on mouse samples at 1:1000 (fig 8). Neuropharmacology (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (H-3)
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 4b
Santa Cruz Biotechnology PTGS2 antibody (Santa Cruz, sc-376861) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig 4b). Front Neurosci (2022) ncbi
mouse monoclonal (D-12)
  • western blot; mouse; 1:1000; loading ...; fig 7a, 7b, 7c, 7d
Santa Cruz Biotechnology PTGS2 antibody (Santa Cruz Biotechnology, sc-166475) was used in western blot on mouse samples at 1:1000 (fig 7a, 7b, 7c, 7d). Aging Dis (2021) ncbi
mouse monoclonal (D-12)
  • western blot; human; loading ...; fig 3a
Santa Cruz Biotechnology PTGS2 antibody (Santa Cruz, sc?\166475) was used in western blot on human samples (fig 3a). J Cell Mol Med (2021) ncbi
mouse monoclonal (H-3)
  • western blot; rat; loading ...; fig 4b
Santa Cruz Biotechnology PTGS2 antibody (Santa, sc-376861) was used in western blot on rat samples (fig 4b). Aging (Albany NY) (2020) ncbi
mouse monoclonal (D-12)
  • western blot; human; loading ...; fig 2f
Santa Cruz Biotechnology PTGS2 antibody (Santa Cruz Biotechnology, sc-166475) was used in western blot on human samples (fig 2f). Aging (Albany NY) (2020) ncbi
mouse monoclonal (H-3)
  • western blot; mouse; 1:500-1:1000; loading ...; fig 3
Santa Cruz Biotechnology PTGS2 antibody (SantaCruz, sc-376861) was used in western blot on mouse samples at 1:500-1:1000 (fig 3). Biol Pharm Bull (2018) ncbi
mouse monoclonal (H-3)
  • immunohistochemistry; rat; 1:100; loading ...; fig 5b
Santa Cruz Biotechnology PTGS2 antibody (Santa Cruz, sc-376861) was used in immunohistochemistry on rat samples at 1:100 (fig 5b). Pharmacol Res (2018) ncbi
mouse monoclonal (29)
  • western blot; human; 1:1000; fig 5a
Santa Cruz Biotechnology PTGS2 antibody (Santa Cruz, sc-19999) was used in western blot on human samples at 1:1000 (fig 5a). Biochem Pharmacol (2017) ncbi
mouse monoclonal (H-3)
  • western blot; rat; loading ...; fig 1b
Santa Cruz Biotechnology PTGS2 antibody (SantaCruz, sc-376861) was used in western blot on rat samples (fig 1b). Mol Cell Biochem (2017) ncbi
mouse monoclonal (H-3)
  • western blot; mouse; loading ...; fig 7
Santa Cruz Biotechnology PTGS2 antibody (SantaCruz, sc-376861) was used in western blot on mouse samples (fig 7). J Ethnopharmacol (2017) ncbi
mouse monoclonal (29)
  • western blot; mouse; 1:1000; fig 6
Santa Cruz Biotechnology PTGS2 antibody (Santa Cruz, sc-19999) was used in western blot on mouse samples at 1:1000 (fig 6). Mediators Inflamm (2016) ncbi
mouse monoclonal (D-12)
  • western blot; mouse; fig 6
Santa Cruz Biotechnology PTGS2 antibody (Santa Cruz, Sc-166475) was used in western blot on mouse samples (fig 6). Int J Mol Sci (2015) ncbi
mouse monoclonal (29)
  • western blot; human; fig 1D
Santa Cruz Biotechnology PTGS2 antibody (Santa Cruz, sc-19999) was used in western blot on human samples (fig 1D). Oncotarget (2015) ncbi
mouse monoclonal (29)
  • western blot; human; fig 3
Santa Cruz Biotechnology PTGS2 antibody (Santa Cruz, sc-19999) was used in western blot on human samples (fig 3). PLoS ONE (2015) ncbi
mouse monoclonal (H-3)
  • western blot; mouse
Santa Cruz Biotechnology PTGS2 antibody (Santa Cruz Biotechnologies, sc-376861) was used in western blot on mouse samples . J Inorg Biochem (2015) ncbi
mouse monoclonal (29)
  • western blot; rat; fig 6
Santa Cruz Biotechnology PTGS2 antibody (Santa Cruz, sc-19999) was used in western blot on rat samples (fig 6). Int J Mol Sci (2015) ncbi
mouse monoclonal (D-12)
  • immunohistochemistry - paraffin section; rat; 1:100
Santa Cruz Biotechnology PTGS2 antibody (Santa Cruz Biotechnology, sc-166475) was used in immunohistochemistry - paraffin section on rat samples at 1:100. J Cell Mol Med (2015) ncbi
mouse monoclonal (D-12)
  • immunohistochemistry; rat; 1:100
Santa Cruz Biotechnology PTGS2 antibody (Santa Cruz Biotechnology, sc-166475) was used in immunohistochemistry on rat samples at 1:100. J Cell Mol Med (2015) ncbi
mouse monoclonal (29)
  • western blot; human
Santa Cruz Biotechnology PTGS2 antibody (Santa Cruz, sc-19999) was used in western blot on human samples . Mol Oncol (2015) ncbi
mouse monoclonal (H-3)
  • western blot; domestic rabbit; 1:2000
Santa Cruz Biotechnology PTGS2 antibody (Santa Cruz Biotechnology, sc-376861) was used in western blot on domestic rabbit samples at 1:2000. Exp Ther Med (2014) ncbi
mouse monoclonal (H-3)
  • western blot; mouse; 1:1000
Santa Cruz Biotechnology PTGS2 antibody (Santa Cruz, sc-376861) was used in western blot on mouse samples at 1:1000. Eur J Pharmacol (2014) ncbi
mouse monoclonal (29)
  • western blot; human
Santa Cruz Biotechnology PTGS2 antibody (Santa Cruz Biotechnology, sc-19999) was used in western blot on human samples . Biochim Biophys Acta (2014) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D5H5)
  • western blot; mouse; loading ...; fig s6c
Cell Signaling Technology PTGS2 antibody (Cell Signaling, 12282) was used in western blot on mouse samples (fig s6c). Commun Biol (2022) ncbi
domestic rabbit monoclonal (D5H5)
  • western blot; mouse; 1:1000; loading ...; fig 2a
  • western blot; rat; 1:1000; loading ...; fig 3a
Cell Signaling Technology PTGS2 antibody (CST, 12282) was used in western blot on mouse samples at 1:1000 (fig 2a) and in western blot on rat samples at 1:1000 (fig 3a). Mediators Inflamm (2022) ncbi
domestic rabbit monoclonal (D5H5)
  • western blot; mouse; 1:1000; loading ...; fig 2b
Cell Signaling Technology PTGS2 antibody (Cell Signaling, 12282) was used in western blot on mouse samples at 1:1000 (fig 2b). Front Immunol (2021) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 6a
Cell Signaling Technology PTGS2 antibody (Cell Signaling, 4842) was used in western blot on human samples (fig 6a). Antioxidants (Basel) (2021) ncbi
domestic rabbit monoclonal (D5H5)
  • immunohistochemistry; human; 1:600; loading ...; fig 4a
Cell Signaling Technology PTGS2 antibody (Cell Signaling Technology, D5H5) was used in immunohistochemistry on human samples at 1:600 (fig 4a). Neuropathol Appl Neurobiol (2021) ncbi
domestic rabbit monoclonal (D5H5)
  • western blot; human; loading ...; fig 1f
Cell Signaling Technology PTGS2 antibody (Cell Signaling, 12282) was used in western blot on human samples (fig 1f). Cell Rep (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:1000; fig 2d
Cell Signaling Technology PTGS2 antibody (Cell Signaling, 4842) was used in immunohistochemistry on mouse samples at 1:1000 (fig 2d). J Immunother Cancer (2021) ncbi
domestic rabbit monoclonal (D5H5)
  • western blot; human; fig 1a
Cell Signaling Technology PTGS2 antibody (Cell Signaling, 12282) was used in western blot on human samples (fig 1a). NPJ Breast Cancer (2020) ncbi
domestic rabbit monoclonal (D5H5)
  • western blot; mouse; 1:2000; loading ...; fig s10b
Cell Signaling Technology PTGS2 antibody (Cell Signaling Technologies, 12282) was used in western blot on mouse samples at 1:2000 (fig s10b). Antioxidants (Basel) (2020) ncbi
domestic rabbit monoclonal (D5H5)
  • western blot; human; 1:1000; loading ...; fig 9b
Cell Signaling Technology PTGS2 antibody (CST Biological Reagents Co, 12282) was used in western blot on human samples at 1:1000 (fig 9b). Int J Mol Med (2020) ncbi
domestic rabbit monoclonal (D5H5)
  • immunohistochemistry - paraffin section; rat; loading ...; fig 3e
Cell Signaling Technology PTGS2 antibody (Cell Signaling, 12282) was used in immunohistochemistry - paraffin section on rat samples (fig 3e). Proc Natl Acad Sci U S A (2020) ncbi
domestic rabbit monoclonal (D5H5)
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 1b
  • immunohistochemistry - paraffin section; rat; loading ...; fig 11b
  • western blot; rat; 1:1000; loading ...; fig 8a
Cell Signaling Technology PTGS2 antibody (Cell Signaling, 12282) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig 1b), in immunohistochemistry - paraffin section on rat samples (fig 11b) and in western blot on rat samples at 1:1000 (fig 8a). Aging (Albany NY) (2020) ncbi
domestic rabbit monoclonal (D5H5)
  • western blot; rat; loading ...; fig 2d
Cell Signaling Technology PTGS2 antibody (Cell Signaling, 12282) was used in western blot on rat samples (fig 2d). Aging (Albany NY) (2019) ncbi
domestic rabbit monoclonal (D5H5)
  • western blot; mouse; 1:1000; loading ...; fig 4b
Cell Signaling Technology PTGS2 antibody (Cell Signaling, 12282) was used in western blot on mouse samples at 1:1000 (fig 4b). Neuropharmacology (2020) ncbi
domestic rabbit monoclonal (D5H5)
  • western blot; human; 1:2000; loading ...; fig 7e
Cell Signaling Technology PTGS2 antibody (Cell signaling, 12282) was used in western blot on human samples at 1:2000 (fig 7e). Biomolecules (2019) ncbi
domestic rabbit monoclonal (D5H5)
  • western blot; mouse; loading ...; fig 6b
Cell Signaling Technology PTGS2 antibody (Cell Signaling, 12282) was used in western blot on mouse samples (fig 6b). Biomed Pharmacother (2019) ncbi
domestic rabbit monoclonal (D5H5)
  • western blot; rat; 1:1000; fig 5d
Cell Signaling Technology PTGS2 antibody (Cell Signaling Technology, 12282s) was used in western blot on rat samples at 1:1000 (fig 5d). J Neuroinflammation (2018) ncbi
domestic rabbit polyclonal
  • other; human; loading ...; fig 4c
Cell Signaling Technology PTGS2 antibody (Cell Signaling, 4842) was used in other on human samples (fig 4c). Cancer Cell (2018) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000
Cell Signaling Technology PTGS2 antibody (Cell Signaling, 4842) was used in western blot on mouse samples at 1:1000. Organogenesis (2018) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:500; fig 5b
  • western blot; human; 1:500; loading ...; fig 6d
Cell Signaling Technology PTGS2 antibody (Cell Signaling, 4842) was used in western blot on mouse samples at 1:500 (fig 5b) and in western blot on human samples at 1:500 (fig 6d). PLoS ONE (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:2000; loading ...; fig 7
In order to determine the capacity of the short isoform of DNAJB6 to protect against 1-methyl-4phenylpridinium ion-induced apoptosis in LN18 cells as a model for Parkinson's disease, Cell Signaling Technology PTGS2 antibody (Cell Signaling, 4842) was used in western blot on human samples at 1:2000 (fig 7). Oxid Med Cell Longev (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 4b
Cell Signaling Technology PTGS2 antibody (Cell signaling, 4842) was used in western blot on human samples (fig 4b). Front Pharmacol (2016) ncbi
domestic rabbit monoclonal (D5H5)
  • western blot; mouse; 1:1000; fig 8
Cell Signaling Technology PTGS2 antibody (Cell Signaling, 12282) was used in western blot on mouse samples at 1:1000 (fig 8). PLoS Pathog (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 5a
Cell Signaling Technology PTGS2 antibody (cell signalling, 4842S) was used in western blot on human samples (fig 5a). Int J Mol Sci (2016) ncbi
domestic rabbit monoclonal (D5H5)
  • immunohistochemistry; human; loading ...; fig 4a
Cell Signaling Technology PTGS2 antibody (Cell Signaling, 12282) was used in immunohistochemistry on human samples (fig 4a). Oncoimmunology (2016) ncbi
domestic rabbit monoclonal (D5H5)
  • western blot; human; loading ...; fig 4c
Cell Signaling Technology PTGS2 antibody (Cell Signaling, 12282) was used in western blot on human samples (fig 4c). J Exp Clin Cancer Res (2016) ncbi
domestic rabbit monoclonal (D5H5)
  • western blot; mouse; fig 5
Cell Signaling Technology PTGS2 antibody (Cell Signaling Technology, 12282) was used in western blot on mouse samples (fig 5). Int J Mol Med (2016) ncbi
domestic rabbit monoclonal (D5H5)
  • western blot; rat; 1:500; fig 1
Cell Signaling Technology PTGS2 antibody (Cell Signaling Technology, 12,282) was used in western blot on rat samples at 1:500 (fig 1). Life Sci (2015) ncbi
domestic rabbit monoclonal (D5H5)
  • western blot; mouse; fig 7c
In order to investigate the impact of ORMDL3 to the mast cell physiology, Cell Signaling Technology PTGS2 antibody (Cell Signaling, 12282) was used in western blot on mouse samples (fig 7c). Cell Mol Life Sci (2016) ncbi
domestic rabbit monoclonal (D5H5)
  • immunohistochemistry - paraffin section; mouse; fig 6b
  • immunohistochemistry - paraffin section; human; fig 6a
  • western blot; human; 1:1000; fig s4i
Cell Signaling Technology PTGS2 antibody (Cell Signalling Technology, 12282) was used in immunohistochemistry - paraffin section on mouse samples (fig 6b), in immunohistochemistry - paraffin section on human samples (fig 6a) and in western blot on human samples at 1:1000 (fig s4i). Nat Commun (2015) ncbi
domestic rabbit monoclonal (D5H5)
  • western blot; mouse; 1:1000; fig 3
In order to assess the effects of Shenling Baizhu San on colitis-associated colorectal cancer, Cell Signaling Technology PTGS2 antibody (CST, D5H5) was used in western blot on mouse samples at 1:1000 (fig 3). BMC Complement Altern Med (2015) ncbi
domestic rabbit monoclonal (D5H5)
  • western blot; human; 1:1000; fig 6
In order to examine the effects of neokestose on cell proliferation, cell cycle, and apoptosis of colonic cells, Cell Signaling Technology PTGS2 antibody (Cell Signaling, 12282) was used in western blot on human samples at 1:1000 (fig 6). Mol Med Rep (2015) ncbi
domestic rabbit monoclonal (D5H5)
  • immunohistochemistry - paraffin section; human; 1:150
  • western blot; human
Cell Signaling Technology PTGS2 antibody (Cell, D5H5) was used in immunohistochemistry - paraffin section on human samples at 1:150 and in western blot on human samples . BMC Cancer (2014) ncbi
domestic rabbit monoclonal (D5H5)
  • western blot; human; 1:500
Cell Signaling Technology PTGS2 antibody (Cell Signaling, 12282) was used in western blot on human samples at 1:500. PPAR Res (2014) ncbi
domestic rabbit monoclonal (D5H5)
  • western blot; mouse
Cell Signaling Technology PTGS2 antibody (Cell Signaling, 12282S) was used in western blot on mouse samples . PLoS ONE (2014) ncbi
Articles Reviewed
  1. Dufour C, Xia H, B chir W, Perry M, Kuzmanov U, Gainullina A, et al. Integrated multi-omics analysis of adverse cardiac remodeling and metabolic inflexibility upon ErbB2 and ERRα deficiency. Commun Biol. 2022;5:955 pubmed publisher
  2. Miao W, Chen M, Chen M, Cui C, Zhu Y, Luo X, et al. Nr2f2 Overexpression Aggravates Ferroptosis and Mitochondrial Dysfunction by Regulating the PGC-1α Signaling in Diabetes-Induced Heart Failure Mice. Mediators Inflamm. 2022;2022:8373389 pubmed publisher
  3. Chen L, Song Z, Cao X, Fan M, Zhou Y, Zhang G. Interleukin-33 regulates the endoplasmic reticulum stress of human myometrium via an influx of calcium during initiation of labor. elife. 2022;11: pubmed publisher
  4. Ji F, Fu X, Li G, He Q, Qiu X. FTO Prevents Thyroid Cancer Progression by SLC7A11 m6A Methylation in a Ferroptosis-Dependent Manner. Front Endocrinol (Lausanne). 2022;13:857765 pubmed publisher
  5. Kong Y, Akatsuka S, Motooka Y, Zheng H, Cheng Z, Shiraki Y, et al. BRCA1 haploinsufficiency promotes chromosomal amplification under Fenton reaction-based carcinogenesis through ferroptosis-resistance. Redox Biol. 2022;54:102356 pubmed publisher
  6. Mastrodonato A, Pavlova I, Kee N, McGowan J, Mann J, Denny C. Acute (R,S)-Ketamine Administration Induces Sex-Specific Behavioral Effects in Adolescent but Not Aged Mice. Front Neurosci. 2022;16:852010 pubmed publisher
  7. Zhao Q, Dai W, Chen H, Jacobs R, Zlokovic B, Lund B, et al. Prenatal disruption of blood-brain barrier formation via cyclooxygenase activation leads to lifelong brain inflammation. Proc Natl Acad Sci U S A. 2022;119:e2113310119 pubmed publisher
  8. Cambria E, Heusser S, Scheuren A, Tam W, Karol A, Hitzl W, et al. TRPV4 mediates cell damage induced by hyperphysiological compression and regulates COX2/PGE2 in intervertebral discs. JOR Spine. 2021;4:e1149 pubmed publisher
  9. Ezenkwa U, Okolo C, Ogun G, Akere A, Ogunbiyi O. Cyclooxygenase-2 expression in colorectal carcinoma, adenomatous polyps and non-tumour bearing margins of resection tissues in a cohort of black Africans. PLoS ONE. 2021;16:e0255235 pubmed publisher
  10. Anandhan A, Nguyen N, Syal A, Dreher L, Dodson M, Zhang D, et al. NRF2 Loss Accentuates Parkinsonian Pathology and Behavioral Dysfunction in Human α-Synuclein Overexpressing Mice. Aging Dis. 2021;12:964-982 pubmed publisher
  11. Qian J, Xu Q, Xu W, Cai R, Huang G. Expression of VEGF-A Signaling Pathway in Cartilage of ACLT-induced Osteoarthritis Mouse Model. J Orthop Surg Res. 2021;16:379 pubmed publisher
  12. Parodi B, Sanna A, Cedola A, Uccelli A, Kerlero de Rosbo N. Hydroxycarboxylic Acid Receptor 2, a Pleiotropically Linked Receptor for the Multiple Sclerosis Drug, Monomethyl Fumarate. Possible Implications for the Inflammatory Response. Front Immunol. 2021;12:655212 pubmed publisher
  13. Lee S, Kim J, Choi Y, Gong J, Park S, Douangdeuane B, et al. Therapeutic Effects of Dipterocarpus tuberculatus with High Antioxidative Activity Against UV-Induced Photoaging of NHDF Cells and Nude Mice. Antioxidants (Basel). 2021;10: pubmed publisher
  14. Zimmer T, Broekaart D, Luinenburg M, Mijnsbergen C, Anink J, Sim N, et al. Balloon cells promote immune system activation in focal cortical dysplasia type 2b. Neuropathol Appl Neurobiol. 2021;47:826-839 pubmed publisher
  15. Li X, Zhou L, Zhang Y, He X, Lu H, Zhang L, et al. mGPDH Deficiency leads to melanoma metastasis via induced NRF2. J Cell Mol Med. 2021;25:5305-5315 pubmed publisher
  16. Zhou H, Li G, Wang Y, Jiang R, Li Y, Wang H, et al. Microbial Metabolite Sodium Butyrate Attenuates Cartilage Degradation by Restoring Impaired Autophagy and Autophagic Flux in Osteoarthritis Development. Front Pharmacol. 2021;12:659597 pubmed publisher
  17. Li M, Haixia Y, Kang M, An P, Wu X, Dang H, et al. The Arachidonic Acid Metabolism Mechanism Based on UPLC-MS/MS Metabolomics in Recurrent Spontaneous Abortion Rats. Front Endocrinol (Lausanne). 2021;12:652807 pubmed publisher
  18. Goncalves S, Yin K, Ito Y, Chan A, Olan I, Gough S, et al. COX2 regulates senescence secretome composition and senescence surveillance through PGE2. Cell Rep. 2021;34:108860 pubmed publisher
  19. Luo Y, Niu G, Yi H, Li Q, Wu Z, Wang J, et al. Nanomedicine promotes ferroptosis to inhibit tumour proliferation in vivo. Redox Biol. 2021;42:101908 pubmed publisher
  20. Ghonim M, Ibba S, Tarhuni A, Errami Y, Luu H, Dean M, et al. Targeting PARP-1 with metronomic therapy modulates MDSC suppressive function and enhances anti-PD-1 immunotherapy in colon cancer. J Immunother Cancer. 2021;9: pubmed publisher
  21. Jindal S, Pennock N, Klug A, Narasimhan J, Calhoun A, Roberts M, et al. S-nitrosylated and non-nitrosylated COX2 have differential expression and distinct subcellular localization in normal and breast cancer tissue. NPJ Breast Cancer. 2020;6:62 pubmed publisher
  22. He F, Li L, Li P, Deng Y, Yang Y, Deng Y, et al. Cyclooxygenase-2/sclerostin mediates TGF-β1-induced calcification in vascular smooth muscle cells and rats undergoing renal failure. Aging (Albany NY). 2020;12:21220-21235 pubmed publisher
  23. Kim H, Hwang S, Sung B, Kim Y, Chang Y. Gd-Complex of a Rosmarinic Acid Conjugate as an Anti-Inflammatory Theranostic Agent via Reactive Oxygen Species Scavenging. Antioxidants (Basel). 2020;9: pubmed publisher
  24. Varela Eirin M, Carpintero Fernández P, Sánchez Temprano A, Varela Vazquez A, Paíno C, Casado Diaz A, et al. Senolytic activity of small molecular polyphenols from olive restores chondrocyte redifferentiation and promotes a pro-regenerative environment in osteoarthritis. Aging (Albany NY). 2020;12:15882-15905 pubmed publisher
  25. Zhu J, Zhen G, An S, Wang X, Wan M, Li Y, et al. Aberrant subchondral osteoblastic metabolism modifies NaV1.8 for osteoarthritis. elife. 2020;9: pubmed publisher
  26. Kong Y, Xu S. Juglanin administration protects skin against UVB‑induced injury by reducing Nrf2‑dependent ROS generation. Int J Mol Med. 2020;46:67-82 pubmed publisher
  27. Di Gregoli K, Somerville M, Bianco R, Thomas A, Frankow A, Newby A, et al. Galectin-3 Identifies a Subset of Macrophages With a Potential Beneficial Role in Atherosclerosis. Arterioscler Thromb Vasc Biol. 2020;40:1491-1509 pubmed publisher
  28. Yang H, Wang L, Zang C, Wang Y, Shang J, Zhang Z, et al. Src Inhibition Attenuates Neuroinflammation and Protects Dopaminergic Neurons in Parkinson's Disease Models. Front Neurosci. 2020;14:45 pubmed publisher
  29. Fong L, Taccioli C, Palamarchuk A, Tagliazucchi G, Jing R, Smalley K, et al. Abrogation of esophageal carcinoma development in miR-31 knockout rats. Proc Natl Acad Sci U S A. 2020;117:6075-6085 pubmed publisher
  30. Wei J, Mattapallil M, Horai R, Jittayasothorn Y, Modi A, Sen H, et al. A novel role for lipoxin A4 in driving a lymph node-eye axis that controls autoimmunity to the neuroretina. elife. 2020;9: pubmed publisher
  31. Jiang L, Xu K, Li J, Zhou X, Xu L, Wu Z, et al. Nesfatin-1 suppresses interleukin-1β-induced inflammation, apoptosis, and cartilage matrix destruction in chondrocytes and ameliorates osteoarthritis in rats. Aging (Albany NY). 2020;12:1760-1777 pubmed publisher
  32. Sozen B, Cox A, De Jonghe J, Bao M, Hollfelder F, Glover D, et al. Self-Organization of Mouse Stem Cells into an Extended Potential Blastoid. Dev Cell. 2019;51:698-712.e8 pubmed publisher
  33. Huang X, Ni B, Xi Y, Chu X, Zhang R, You H. Protease-activated receptor 2 (PAR-2) antagonist AZ3451 as a novel therapeutic agent for osteoarthritis. Aging (Albany NY). 2019;11:12532-12545 pubmed publisher
  34. Jiang X, Xu C, Shi H, Cheng Q. PTH1-34 improves bone healing by promoting angiogenesis and facilitating MSCs migration and differentiation in a stabilized fracture mouse model. PLoS ONE. 2019;14:e0226163 pubmed publisher
  35. Wang X, Chang Y, He Y, Lyu C, Li H, Zhu J, et al. Glimepiride and glibenclamide have comparable efficacy in treating acute ischemic stroke in mice. Neuropharmacology. 2020;162:107845 pubmed publisher
  36. Tu M, Yang M, Yu N, Zhen G, Wan M, Liu W, et al. Inhibition of cyclooxygenase-2 activity in subchondral bone modifies a subtype of osteoarthritis. Bone Res. 2019;7:29 pubmed publisher
  37. Singh M, Kasna S, Roy S, Aldosary S, Saeedan A, Ansari M, et al. Repurposing mechanistic insight of PDE-5 inhibitor in cancer chemoprevention through mitochondrial-oxidative stress intervention and blockade of DuCLOX signalling. BMC Cancer. 2019;19:996 pubmed publisher
  38. Roy N, Monisha J, Padmavathi G, Lalhruaitluanga H, Kumar N, Singh A, et al. Isoform-Specific Role of Akt in Oral Squamous Cell Carcinoma. Biomolecules. 2019;9: pubmed publisher
  39. Cao H, Wang Q, Gao Z, Xu X, Lu Q, Wu Y. Clinical value of detecting IQGAP3, B7-H4 and cyclooxygenase-2 in the diagnosis and prognostic evaluation of colorectal cancer. Cancer Cell Int. 2019;19:163 pubmed publisher
  40. Fang D, Wang H, Li M, Wei W. α-bisabolol enhances radiotherapy-induced apoptosis in endometrial cancer cells by reducing the effect of XIAP on inhibiting caspase-3. Biosci Rep. 2019;39: pubmed publisher
  41. Feng F, Wang Z, Li R, Wu Q, Gu C, Xu Y, et al. Citrus alkaline extracts prevent fibroblast senescence to ameliorate pulmonary fibrosis via activation of COX-2. Biomed Pharmacother. 2019;112:108669 pubmed publisher
  42. Chen H, Hu B, Lv X, Zhu S, Zhen G, Wan M, et al. Prostaglandin E2 mediates sensory nerve regulation of bone homeostasis. Nat Commun. 2019;10:181 pubmed publisher
  43. Qiu L, Wang M, Hu S, Ru X, Ren Y, Zhang Z, et al. Oncogenic Activation of Nrf2, Though as a Master Antioxidant Transcription Factor, Liberated by Specific Knockout of the Full-Length Nrf1α that Acts as a Dominant Tumor Repressor. Cancers (Basel). 2018;10: pubmed publisher
  44. Suzuki S, Tanaka A, Nakamura H, Murayama T. Knockout of Ceramide Kinase Aggravates Pathological and Lethal Responses in Mice with Experimental Colitis. Biol Pharm Bull. 2018;41:797-805 pubmed publisher
  45. Zhang P, Bi R, Gan Y. Glial interleukin-1β upregulates neuronal sodium channel 1.7 in trigeminal ganglion contributing to temporomandibular joint inflammatory hypernociception in rats. J Neuroinflammation. 2018;15:117 pubmed publisher
  46. Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  47. Sun J, Wang Z, Wang X. Suppression of LRRC19 promotes cutaneous wound healing in pressure ulcers in mice. Organogenesis. 2018;14:13-24 pubmed publisher
  48. Bogdan D, Falcone J, Kanjiya M, Park S, Carbonetti G, Studholme K, et al. Fatty acid-binding protein 5 controls microsomal prostaglandin E synthase 1 (mPGES-1) induction during inflammation. J Biol Chem. 2018;293:5295-5306 pubmed publisher
  49. Gugliandolo E, Fusco R, D Amico R, Militi A, Oteri G, Wallace J, et al. Anti-inflammatory effect of ATB-352, a H2S -releasing ketoprofen derivative, on lipopolysaccharide-induced periodontitis in rats. Pharmacol Res. 2018;132:220-231 pubmed publisher
  50. Paterniti I, Campolo M, Siracusa R, Cordaro M, Di Paola R, Calabrese V, et al. Liver X receptors activation, through TO901317 binding, reduces neuroinflammation in Parkinson's disease. PLoS ONE. 2017;12:e0174470 pubmed publisher
  51. Yang C, Chen Y, Chi P, Lin C, Hsiao L. Resveratrol inhibits BK-induced COX-2 transcription by suppressing acetylation of AP-1 and NF-?B in human rheumatoid arthritis synovial fibroblasts. Biochem Pharmacol. 2017;132:77-91 pubmed publisher
  52. Hong Y, Hong Y, Choi Y, Yeo S, Jin S, Lee S, et al. The Short Isoform of DNAJB6 Protects against 1-Methyl-4-phenylpridinium Ion-Induced Apoptosis in LN18 Cells via Inhibiting Both ROS Formation and Mitochondrial Membrane Potential Loss. Oxid Med Cell Longev. 2017;2017:7982389 pubmed publisher
  53. Maayah Z, Althurwi H, El Sherbeni A, Abdelhamid G, Siraki A, El Kadi A. The role of cytochrome P450 1B1 and its associated mid-chain hydroxyeicosatetraenoic acid metabolites in the development of cardiac hypertrophy induced by isoproterenol. Mol Cell Biochem. 2017;429:151-165 pubmed publisher
  54. de Oliveira R, de Campos Castilho G, da Cunha A, Miyajima F, de Oliveira Martins D. Dilodendron bipinnatum Radlk. inhibits pro-inflammatory mediators through the induction of MKP-1 and the down-regulation of MAPKp38/JNK/NF-?B pathways and COX-2 in LPS-activated RAW 264.7 cells. J Ethnopharmacol. 2017;202:127-137 pubmed publisher
  55. Yang X, Huo F, Liu B, Liu J, Chen T, Li J, et al. Crocin Inhibits Oxidative Stress and Pro-inflammatory Response of Microglial Cells Associated with Diabetic Retinopathy Through the Activation of PI3K/Akt Signaling Pathway. J Mol Neurosci. 2017;61:581-589 pubmed publisher
  56. Indrakusuma I, Romacho T, Eckel J. Protease-Activated Receptor 2 Promotes Pro-Atherogenic Effects through Transactivation of the VEGF Receptor 2 in Human Vascular Smooth Muscle Cells. Front Pharmacol. 2016;7:497 pubmed publisher
  57. Yabuki A, Miyazaki A, Ichii O, Kohyama M, Sawa M, Yamato O. Low expression of cyclooxygenase-2 in chronic kidney disease in young dogs. Res Vet Sci. 2016;109:71-73 pubmed publisher
  58. Yun C, Jung Y, Chun W, Yang B, Ryu J, Lim C, et al. Anti-Inflammatory Effects of Artemisia Leaf Extract in Mice with Contact Dermatitis In Vitro and In Vivo. Mediators Inflamm. 2016;2016:8027537 pubmed publisher
  59. Carvalho S, Stoll A, Priestnall S, Suárez Bonnet A, Rassnick K, Lynch S, et al. Retrospective evaluation of COX-2 expression, histological and clinical factors as prognostic indicators in dogs with renal cell carcinomas undergoing nephrectomy. Vet Comp Oncol. 2017;15:1280-1294 pubmed publisher
  60. Wang X, Shaw D, Hammond H, Sutterwala F, Rayamajhi M, Shirey K, et al. The Prostaglandin E2-EP3 Receptor Axis Regulates Anaplasma phagocytophilum-Mediated NLRC4 Inflammasome Activation. PLoS Pathog. 2016;12:e1005803 pubmed publisher
  61. Lee J, Yu K, Kim H, Kang I, Kim J, Lee B, et al. BMI1 inhibits senescence and enhances the immunomodulatory properties of human mesenchymal stem cells via the direct suppression of MKP-1/DUSP1. Aging (Albany NY). 2016;8:1670-89 pubmed publisher
  62. Hafez N, Tahoun N. Expression of cyclooxygenase 2 and vascular endothelial growth factor in gastric carcinoma: Relationship with clinicopathological parameters. J Egypt Natl Canc Inst. 2016;28:149-56 pubmed publisher
  63. Müller S, Acevedo L, Wang X, Karim M, Matta A, Mehrkens A, et al. Notochordal cell conditioned medium (NCCM) regenerates end-stage human osteoarthritic articular chondrocytes and promotes a healthy phenotype. Arthritis Res Ther. 2016;18:125 pubmed publisher
  64. Hudson C, McArdle C, López Bernal A. Steroid receptor co-activator interacting protein (SIP) mediates EGF-stimulated expression of the prostaglandin synthase COX2 and prostaglandin release in human myometrium. Mol Hum Reprod. 2016;22:512-25 pubmed publisher
  65. Wang X, Wang N, Li H, Liu M, Cao F, Yu X, et al. Up-Regulation of PAI-1 and Down-Regulation of uPA Are Involved in Suppression of Invasiveness and Motility of Hepatocellular Carcinoma Cells by a Natural Compound Berberine. Int J Mol Sci. 2016;17:577 pubmed publisher
  66. Lin A, Wang G, Zhao H, Zhang Y, Han Q, Zhang C, et al. TLR4 signaling promotes a COX-2/PGE2/STAT3 positive feedback loop in hepatocellular carcinoma (HCC) cells. Oncoimmunology. 2016;5:e1074376 pubmed
  67. Li J, Tang C, Li L, Li R, Fan Y. Quercetin sensitizes glioblastoma to t-AUCB by dual inhibition of Hsp27 and COX-2 in vitro and in vivo. J Exp Clin Cancer Res. 2016;35:61 pubmed publisher
  68. Szylberg Å, Janiczek M, Popiel A, MarszaÅ‚ek A. Expression of COX-2, IL-1β, TNF-α and IL-4 in epithelium of serrated adenoma, adenoma and hyperplastic polyp. Arch Med Sci. 2016;12:172-8 pubmed publisher
  69. Abu N, Akhtar M, Yeap S, Lim K, Ho W, Abdullah M, et al. Flavokawain B induced cytotoxicity in two breast cancer cell lines, MCF-7 and MDA-MB231 and inhibited the metastatic potential of MDA-MB231 via the regulation of several tyrosine kinases In vitro. BMC Complement Altern Med. 2016;16:86 pubmed publisher
  70. Tsaousi A, Hayes E, Di Gregoli K, Bond A, Bevan L, Thomas A, et al. Plaque Size Is Decreased but M1 Macrophage Polarization and Rupture Related Metalloproteinase Expression Are Maintained after Deleting T-Bet in ApoE Null Mice. PLoS ONE. 2016;11:e0148873 pubmed publisher
  71. Ding X, Pan L, Wang Y, Xu Q. Baicalin exerts protective effects against lipopolysaccharide-induced acute lung injury by regulating the crosstalk between the CX3CL1-CX3CR1 axis and NF-κB pathway in CX3CL1-knockout mice. Int J Mol Med. 2016;37:703-15 pubmed publisher
  72. Chiou S, Ha C, Wu P, Yeh C, Su Y, Li M, et al. Antioxidant, Anti-Tyrosinase and Anti-Inflammatory Activities of Oil Production Residues from Camellia tenuifloria. Int J Mol Sci. 2015;16:29522-41 pubmed publisher
  73. Yang T, Hsu P, Meng M, Su C. Supplement of 5-hydroxytryptophan before induction suppresses inflammation and collagen-induced arthritis. Arthritis Res Ther. 2015;17:364 pubmed publisher
  74. Lowin T, Apitz M, Anders S, Straub R. Anti-inflammatory effects of N-acylethanolamines in rheumatoid arthritis synovial cells are mediated by TRPV1 and TRPA1 in a COX-2 dependent manner. Arthritis Res Ther. 2015;17:321 pubmed publisher
  75. Sabogal Guáqueta A, Osorio E, Cardona Gómez G. Linalool reverses neuropathological and behavioral impairments in old triple transgenic Alzheimer's mice. Neuropharmacology. 2016;102:111-20 pubmed publisher
  76. Lu S, Yang Y, Du Y, Cao L, Li M, Shen C, et al. The transcription factor c-Fos coordinates with histone lysine-specific demethylase 2A to activate the expression of cyclooxygenase-2. Oncotarget. 2015;6:34704-17 pubmed publisher
  77. Radhika N, Govindaraj V, Sarangi S, Rao A. Neonatal exposure to 17β-estradiol down-regulates the expression of synaptogenesis related genes in selected brain regions of adult female rats. Life Sci. 2015;141:1-7 pubmed publisher
  78. Bugajev V, Hálová I, Dráberová L, Bambousková M, Potůčková L, Draberova H, et al. Negative regulatory roles of ORMDL3 in the FcεRI-triggered expression of proinflammatory mediators and chemotactic response in murine mast cells. Cell Mol Life Sci. 2016;73:1265-85 pubmed publisher
  79. Kim J, Sato M, Choi J, Kim H, Yeh B, Larsen J, et al. Nuclear Receptor Expression and Function in Human Lung Cancer Pathogenesis. PLoS ONE. 2015;10:e0134842 pubmed publisher
  80. Chew G, Huo C, Huang D, Hill P, Cawson J, Frazer H, et al. Increased COX-2 expression in epithelial and stromal cells of high mammographic density tissues and in a xenograft model of mammographic density. Breast Cancer Res Treat. 2015;153:89-99 pubmed publisher
  81. Pogue A, Dua P, Hill J, Lukiw W. Progressive inflammatory pathology in the retina of aluminum-fed 5xFAD transgenic mice. J Inorg Biochem. 2015;152:206-9 pubmed publisher
  82. Remo A, Simeone I, Pancione M, Parcesepe P, Finetti P, Cerulo L, et al. Systems biology analysis reveals NFAT5 as a novel biomarker and master regulator of inflammatory breast cancer. J Transl Med. 2015;13:138 pubmed publisher
  83. SCANLON C, Banerjee R, Inglehart R, Liu M, Russo N, Hariharan A, et al. Galanin modulates the neural niche to favour perineural invasion in head and neck cancer. Nat Commun. 2015;6:6885 pubmed publisher
  84. Lin X, Xu W, Shao M, Fan Q, Wen G, Li C, et al. Shenling Baizhu San supresses colitis associated colorectal cancer through inhibition of epithelial-mesenchymal transition and myeloid-derived suppressor infiltration. BMC Complement Altern Med. 2015;15:126 pubmed publisher
  85. Lee S, Chang J, Wu J, Sheu D. Antineoplastic effect of a novel chemopreventive agent, neokestose, on the Caco-2 cell line via inhibition of expression of nuclear factor-κB and cyclooxygenase-2. Mol Med Rep. 2015;12:1114-8 pubmed publisher
  86. Giunta S, Castorina A, Marzagalli R, Szychlinska M, Pichler K, Mobasheri A, et al. Ameliorative effects of PACAP against cartilage degeneration. Morphological, immunohistochemical and biochemical evidence from in vivo and in vitro models of rat osteoarthritis. Int J Mol Sci. 2015;16:5922-44 pubmed publisher
  87. Yang J, Chi C, Liu Z, Yang G, Shen Z, Yang X. Ultrastructure damage of oviduct telocytes in rat model of acute salpingitis. J Cell Mol Med. 2015;19:1720-8 pubmed publisher
  88. Rodríguez F, Poveda J, Jaber J, Orós J, Rodríguez J. Expression of cyclooxygenase-2 in the mammary gland tissue of goats affected with caprine contagious agalactia. Vet J. 2015;204:125-7 pubmed publisher
  89. Saraiva A, Payan Carreira R, Gärtner F, Santana I, Rêma A, Lourenço L, et al. Immunohistochemical expression of cyclooxygenase-2 (COX-2) in feline endometrial adenocarcinoma and in normal and hyperplastic endometria. Reprod Domest Anim. 2015;50:333-40 pubmed publisher
  90. Yang X, Yang J, Liu Z, Yang G, Shen Z. Telocytes damage in endometriosis-affected rat oviduct and potential impact on fertility. J Cell Mol Med. 2015;19:452-62 pubmed publisher
  91. Lei Q, Qiang F, Chao D, Di W, Guoqian Z, Bo Y, et al. Amelioration of hypoxia and LPS-induced intestinal epithelial barrier dysfunction by emodin through the suppression of the NF-κB and HIF-1α signaling pathways. Int J Mol Med. 2014;34:1629-39 pubmed publisher
  92. Urban J, Kuźbicki Å, Szatkowski G, Stanek Widera A, Lange D, Chwirot B. Stromal, rather than epithelial cyclooxygenase-2 (COX-2) expression is associated with overall survival of breast cancer patients. BMC Cancer. 2014;14:732 pubmed publisher
  93. Hamdollah Zadeh M, Amin E, Hoareau Aveilla C, Domingo E, Symonds K, Ye X, et al. Alternative splicing of TIA-1 in human colon cancer regulates VEGF isoform expression, angiogenesis, tumour growth and bevacizumab resistance. Mol Oncol. 2015;9:167-78 pubmed publisher
  94. Bhat I, Rasool R, Qasim I, Masoodi K, Paul S, Bhat B, et al. COX-2 overexpression and -8473 T/C polymorphism in 3' UTR in non-small cell lung cancer. Tumour Biol. 2014;35:11209-18 pubmed publisher
  95. Gao Y, Chen Y, Xu D, Wang J, Yu G. Differential expression of ANXA1 in benign human gastrointestinal tissues and cancers. BMC Cancer. 2014;14:520 pubmed publisher
  96. Stodden G, Lindberg M, King M, Paquet M, MacLean J, Mann J, et al. Loss of Cdh1 and Trp53 in the uterus induces chronic inflammation with modification of tumor microenvironment. Oncogene. 2015;34:2471-82 pubmed publisher
  97. Basak K, Doguc D, Aylak F, Karadayi N, Gultekin F. Effects of maternally exposed food coloring additives on laryngeal histology in rats. J Environ Pathol Toxicol Oncol. 2014;33:123-30 pubmed
  98. Pomianowska E, Sandnes D, Grzyb K, Schjølberg A, Aasrum M, Tveteraas I, et al. Inhibitory effects of prostaglandin E2 on collagen synthesis and cell proliferation in human stellate cells from pancreatic head adenocarcinoma. BMC Cancer. 2014;14:413 pubmed publisher
  99. Malaviya A, Sylvester P. Synergistic Antiproliferative Effects of Combined ? -Tocotrienol and PPAR ? Antagonist Treatment Are Mediated through PPAR ? -Independent Mechanisms in Breast Cancer Cells. PPAR Res. 2014;2014:439146 pubmed publisher
  100. Sharma A, Huard C, Vernochet C, Ziemek D, Knowlton K, Tyminski E, et al. Brown fat determination and development from muscle precursor cells by novel action of bone morphogenetic protein 6. PLoS ONE. 2014;9:e92608 pubmed publisher
  101. Wang L, Wang J, Wang Y, Fu Q, Lei Y, Nie Z, et al. Protective effect of exogenous matrix metalloproteinase-9 on chronic renal failure. Exp Ther Med. 2014;7:329-334 pubmed
  102. Chen H, Sohn J, Zhang L, Tian J, Chen S, Bjeldanes L. Anti-inflammatory effects of chicanine on murine macrophage by down-regulating LPS-induced inflammatory cytokines in I?B?/MAPK/ERK signaling pathways. Eur J Pharmacol. 2014;724:168-74 pubmed publisher
  103. Ramyaa P, Krishnaswamy R, Padma V. Quercetin modulates OTA-induced oxidative stress and redox signalling in HepG2 cells - up regulation of Nrf2 expression and down regulation of NF-?B and COX-2. Biochim Biophys Acta. 2014;1840:681-92 pubmed publisher
  104. Jourdain A, Koppen M, Wydro M, Rodley C, Lightowlers R, Chrzanowska Lightowlers Z, et al. GRSF1 regulates RNA processing in mitochondrial RNA granules. Cell Metab. 2013;17:399-410 pubmed publisher
  105. Taskin S, Dunder I, Erol E, Taşkin E, Kiremitci S, Oztuna D, et al. Roles of E-cadherin and cyclooxygenase enzymes in predicting different survival patterns of optimally cytoreduced serous ovarian cancer patients. Asian Pac J Cancer Prev. 2012;13:5715-9 pubmed
  106. Czachorowski M, Amaral A, Montes Moreno S, Lloreta J, Carrato A, Tardon A, et al. Cyclooxygenase-2 expression in bladder cancer and patient prognosis: results from a large clinical cohort and meta-analysis. PLoS ONE. 2012;7:e45025 pubmed publisher
  107. Haligur M, Topsakal S, Ozmen O. Early degenerative effects of diabetes mellitus on pancreas, liver, and kidney in rats: an immunohistochemical study. Exp Diabetes Res. 2012;2012:120645 pubmed publisher
  108. Oláh O, Nemeth I, Toth Szuki V, Bari F, Domoki F. Regional Differences in the Neuronal Expression of Cyclooxygenase-2 (COX-2) in the Newborn Pig Brain. Acta Histochem Cytochem. 2012;45:187-92 pubmed publisher
  109. Lundström S, Levänen B, Nording M, Klepczynska Nyström A, Sköld M, Haeggstrom J, et al. Asthmatics exhibit altered oxylipin profiles compared to healthy individuals after subway air exposure. PLoS ONE. 2011;6:e23864 pubmed publisher
  110. Luo H, Chen Z, Jin H, Zhuang M, Wang T, Su C, et al. Cyclooxygenase-2 up-regulates vascular endothelial growth factor via a protein kinase C pathway in non-small cell lung cancer. J Exp Clin Cancer Res. 2011;30:6 pubmed publisher
  111. Shiirevnyamba A, Takahashi T, Shan H, Ogawa H, Yano S, Kanayama H, et al. Enhancement of osteoclastogenic activity in osteolytic prostate cancer cells by physical contact with osteoblasts. Br J Cancer. 2011;104:505-13 pubmed publisher
  112. Lage K, Møllgård K, Greenway S, Wakimoto H, Gorham J, Workman C, et al. Dissecting spatio-temporal protein networks driving human heart development and related disorders. Mol Syst Biol. 2010;6:381 pubmed publisher
  113. Daugaard S, Christensen L, Høgdall E. Markers aiding the diagnosis of chondroid tumors: an immunohistochemical study including osteonectin, bcl-2, cox-2, actin, calponin, D2-40 (podoplanin), mdm-2, CD117 (c-kit), and YKL-40. APMIS. 2009;117:518-25 pubmed publisher
  114. Gil da Costa R, Santos M, Amorim I, Lopes C, Pereira P, Faustino A. An immunohistochemical study of feline endometrial adenocarcinoma. J Comp Pathol. 2009;140:254-9 pubmed publisher
  115. Maloney S, Fernandes B, Castiglione E, Antecka E, Martins C, Marshall J, et al. Expression of cyclooxygenase-2 in choroidal neovascular membranes from age-related macular degeneration patients. Retina. 2009;29:176-80 pubmed publisher
  116. Sackett M, Bairati I, Meyer F, Jobin E, Lussier S, Fortin A, et al. Prognostic significance of cyclooxygenase-2 overexpression in glottic cancer. Clin Cancer Res. 2008;14:67-73 pubmed publisher
  117. Ketabchi S, Massi D, Ficarra G, Rubino I, Franchi A, Paglierani M, et al. Expression of protease-activated receptor-1 and -2 in orofacial granulomatosis. Oral Dis. 2007;13:419-25 pubmed
  118. Buccoliero A, Castiglione F, Rossi Degl Innocenti D, Arganini L, Taddei A, Ammannati F, et al. Cyclooxygenase-2 (COX-2) overexpression in meningiomas: real time PCR and immunohistochemistry. Appl Immunohistochem Mol Morphol. 2007;15:187-92 pubmed
  119. Bianchini F, Massi D, Marconi C, Franchi A, Baroni G, Santucci M, et al. Expression of cyclo-oxygenase-2 in macrophages associated with cutaneous melanoma at different stages of progression. Prostaglandins Other Lipid Mediat. 2007;83:320-8 pubmed
  120. Marshall J, Fernandes B, Di Cesare S, Maloney S, Logan P, Antecka E, et al. The use of a cyclooxygenase-2 inhibitor (Nepafenac) in an ocular and metastatic animal model of uveal melanoma. Carcinogenesis. 2007;28:2053-8 pubmed
  121. Kim K, Kim S, Kim S, Back J, Park M, Kim J. Cyclooxygenase-2 and inducible nitric oxide synthase expression in thyroid neoplasms and their clinicopathological correlation. J Korean Med Sci. 2006;21:1064-9 pubmed
  122. Souza Filho J, Martins M, Correa Z, Odashiro A, Antecka E, Coutinho A, et al. The expression of cyclooxygenase 2 in retinoblastoma: primary enucleated eyes and enucleation after conservative treatment. Am J Ophthalmol. 2006;142:625-31 pubmed
  123. Asaad N, Sadek G. Pulmonary cryptosporidiosis: role of COX2 and NF-kB. APMIS. 2006;114:682-9 pubmed
  124. Bodey B, Siegel S, Kaiser H. Cyclooxygenase-2 (COX-2) overexpression in childhood brain tumors. In Vivo. 2006;20:519-25 pubmed