This is a Validated Antibody Database (VAD) review about human PRKCI, based on 5 published articles (read how Labome selects the articles), using PRKCI antibody in all methods. It is aimed to help Labome visitors find the most suited PRKCI antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
PRKCI synonym: DXS1179E; PKCI; nPKC-iota; protein kinase C iota type; PRKC-lambda/iota; aPKC-lambda/iota; atypical protein kinase C-lambda/iota

R&D Systems
sheep polyclonal
  • immunohistochemistry - frozen section; mouse
In order to study the role of Crumbs3 in proper epithelial development and viability, R&D Systems PRKCI antibody (R&D, AF4465) was used in immunohistochemistry - frozen section on mouse samples . Mol Cell Biol (2014) ncbi
Invitrogen
rabbit polyclonal
  • western blot; dog; loading ...; fig 1c
In order to determine the contribution of protein kinase C iota to normal-polarized mammalian morphogenesis, Invitrogen PRKCI antibody (Invitrogen, 44-968G) was used in western blot on dog samples (fig 1c). Carcinogenesis (2014) ncbi
Cell Signaling Technology
rabbit monoclonal (C83H11)
  • western blot; human; loading ...; fig 1a
In order to study the effect of GNAQ mutations and GNA11/MAPK pathway activation in uveal melanoma, Cell Signaling Technology PRKCI antibody (Cell Signaling, 2998) was used in western blot on human samples (fig 1a). Cancer Cell (2017) ncbi
rabbit monoclonal (C83H11)
  • western blot; mouse; loading ...; fig s1a
Cell Signaling Technology PRKCI antibody (Cell Signaling, C83H11) was used in western blot on mouse samples (fig s1a). Proc Natl Acad Sci U S A (2017) ncbi
rabbit monoclonal (C83H11)
  • western blot; mouse; 1:500; loading ...; fig 3a
Cell Signaling Technology PRKCI antibody (Cell Signaling, 2998) was used in western blot on mouse samples at 1:500 (fig 3a). elife (2016) ncbi
Articles Reviewed
  1. Chen X, Wu Q, Depeille P, Chen P, Thornton S, Kalirai H, et al. RasGRP3 Mediates MAPK Pathway Activation in GNAQ Mutant Uveal Melanoma. Cancer Cell. 2017;31:685-696.e6 pubmed publisher
  2. Li Q, Navakkode S, Rothkegel M, Soong T, Sajikumar S, Korte M. Metaplasticity mechanisms restore plasticity and associativity in an animal model of Alzheimer's disease. Proc Natl Acad Sci U S A. 2017;114:5527-5532 pubmed publisher
  3. Tsokas P, Hsieh C, Yao Y, Lesburguères E, Wallace E, Tcherepanov A, et al. Compensation for PKM? in long-term potentiation and spatial long-term memory in mutant mice. elife. 2016;5: pubmed publisher
  4. Whiteman E, Fan S, Harder J, Walton K, Liu C, Soofi A, et al. Crumbs3 is essential for proper epithelial development and viability. Mol Cell Biol. 2014;34:43-56 pubmed publisher
  5. Linch M, Sanz Garcia M, Rosse C, Riou P, Peel N, Madsen C, et al. Regulation of polarized morphogenesis by protein kinase C iota in oncogenic epithelial spheroids. Carcinogenesis. 2014;35:396-406 pubmed publisher