This is a Validated Antibody Database (VAD) review about human PPP2CB, based on 17 published articles (read how Labome selects the articles), using PPP2CB antibody in all methods. It is aimed to help Labome visitors find the most suited PPP2CB antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
PPP2CB synonym: PP2Abeta; PP2CB

Santa Cruz Biotechnology
mouse monoclonal (F-8)
  • immunohistochemistry - paraffin section; mouse; 1:50; loading ...; fig 3d
  • western blot; mouse; 1:100; loading ...; fig 7a
Santa Cruz Biotechnology PPP2CB antibody (Santa Cruz, sc-271903) was used in immunohistochemistry - paraffin section on mouse samples at 1:50 (fig 3d) and in western blot on mouse samples at 1:100 (fig 7a). Commun Biol (2021) ncbi
mouse monoclonal (2A10)
  • western blot; rat; loading ...; fig 4g
  • western blot; human; loading ...; fig 7e
Santa Cruz Biotechnology PPP2CB antibody (Santa Cruz, sc-81603) was used in western blot on rat samples (fig 4g) and in western blot on human samples (fig 7e). Aging (Albany NY) (2020) ncbi
mouse monoclonal (F-8)
  • western blot; human; loading ...; fig 1i
Santa Cruz Biotechnology PPP2CB antibody (Santa Cruz Biotechnology, sc-271903) was used in western blot on human samples (fig 1i). Mol Cell (2019) ncbi
mouse monoclonal (F-8)
  • immunoprecipitation; human; loading ...; fig 6a
  • immunocytochemistry; human; loading ...; fig 4c
  • western blot; human; loading ...; fig 6a
Santa Cruz Biotechnology PPP2CB antibody (Santa Cruz Biotechnology, sc-271903) was used in immunoprecipitation on human samples (fig 6a), in immunocytochemistry on human samples (fig 4c) and in western blot on human samples (fig 6a). Oncotarget (2017) ncbi
mouse monoclonal (4B7)
  • immunoprecipitation; rat; 1:300
  • western blot; rat
In order to report the signaling mechanisms by which PKC-zeta activation affects EMAP-II-induced BTB hyperpermeability, Santa Cruz Biotechnology PPP2CB antibody (Santa Cruz, sc-13601) was used in immunoprecipitation on rat samples at 1:300 and in western blot on rat samples . Exp Cell Res (2015) ncbi
mouse monoclonal (4B7)
  • western blot; rat
Santa Cruz Biotechnology PPP2CB antibody (Santa Cruz Biotechnology, sc-13601) was used in western blot on rat samples . Brain Res (2015) ncbi
mouse monoclonal (C-1)
  • western blot; human; loading ...; fig 2a
Santa Cruz Biotechnology PPP2CB antibody (SantaCruz, sc-376673) was used in western blot on human samples (fig 2a). PLoS ONE (2014) ncbi
mouse monoclonal (G-4)
  • western blot; human; 1:1000; fig 7
Santa Cruz Biotechnology PPP2CB antibody (Santa Cruz Biotechnology, sc-166034) was used in western blot on human samples at 1:1000 (fig 7). FEBS Lett (2014) ncbi
mouse monoclonal (2A10)
  • western blot; rat
Santa Cruz Biotechnology PPP2CB antibody (Santa Cruz Biotechnology, sc-81603) was used in western blot on rat samples . J Appl Physiol (1985) (2012) ncbi
Abcam
domestic rabbit monoclonal (Y119)
  • western blot; human; loading ...; fig 5a
Abcam PPP2CB antibody (Abcam, ab32141) was used in western blot on human samples (fig 5a). Cell Death Differ (2021) ncbi
domestic rabbit monoclonal (E155)
  • western blot; mouse; loading ...; fig 1b
Abcam PPP2CB antibody (Abcam, ab32104) was used in western blot on mouse samples (fig 1b). Cell Rep (2020) ncbi
domestic rabbit monoclonal (Y119)
  • immunocytochemistry; mouse; 1:250; loading ...; fig 6
  • western blot; mouse; 1:1000; loading ...; fig 5
In order to analyze the effects of Resveratrol on Neuro-2a cells prior to and after formaldehyde exposure, Abcam PPP2CB antibody (Abcam, ab32141) was used in immunocytochemistry on mouse samples at 1:250 (fig 6) and in western blot on mouse samples at 1:1000 (fig 5). Front Neurosci (2016) ncbi
domestic rabbit monoclonal (E155)
  • western blot; mouse; 1:1000; fig 3
In order to assess induction of synaptic impairment and memory deficit by calcieurin-mediated inactivation of nuclear CaMKIV/CREB signaling due to tau accumulation, Abcam PPP2CB antibody (Abcam, ab32104) was used in western blot on mouse samples at 1:1000 (fig 3). Proc Natl Acad Sci U S A (2016) ncbi
domestic rabbit monoclonal (E155)
  • western blot; human
Abcam PPP2CB antibody (Abcam, ab32104) was used in western blot on human samples . Sci Rep (2016) ncbi
domestic rabbit monoclonal (E155)
  • western blot; human; fig 6
Abcam PPP2CB antibody (Abcam, ab32104) was used in western blot on human samples (fig 6). Oncotarget (2016) ncbi
domestic rabbit monoclonal (E155)
  • immunocytochemistry; rat; 1:200
  • western blot; rat; 1:1000
  • western blot; human; 1:1000; fig 4
Abcam PPP2CB antibody (Abcam, ab32104) was used in immunocytochemistry on rat samples at 1:200, in western blot on rat samples at 1:1000 and in western blot on human samples at 1:1000 (fig 4). Neurochem Int (2013) ncbi
domestic rabbit monoclonal (E155)
  • western blot; rat; 1:500
  • western blot; dogs; 1:500
  • western blot; human; 1:500
  • western blot; mouse; 1:500
Abcam PPP2CB antibody (Abcam, ab32104) was used in western blot on rat samples at 1:500, in western blot on dogs samples at 1:500, in western blot on human samples at 1:500 and in western blot on mouse samples at 1:500. J Biol Chem (2013) ncbi
Articles Reviewed
  1. Yen Y, Chien M, Wu P, Hung S. PP2A in LepR+ mesenchymal stem cells contributes to embryonic and postnatal endochondral ossification through Runx2 dephosphorylation. Commun Biol. 2021;4:658 pubmed publisher
  2. Grisan F, Iannucci L, Surdo N, Gerbino A, Zanin S, Di Benedetto G, et al. PKA compartmentalization links cAMP signaling and autophagy. Cell Death Differ. 2021;28:2436-2449 pubmed publisher
  3. Kitada M, Ogura Y, Monno I, Xu J, Koya D. Methionine abrogates the renoprotective effect of a low-protein diet against diabetic kidney disease in obese rats with type 2 diabetes. Aging (Albany NY). 2020;12:4489-4505 pubmed publisher
  4. Frohner I, Mudrak I, Schüchner S, Anrather D, Hartl M, Sontag J, et al. PP2AC Phospho-Tyr307 Antibodies Are Not Specific for this Modification but Are Sensitive to Other PP2AC Modifications Including Leu309 Methylation. Cell Rep. 2020;30:3171-3182.e6 pubmed publisher
  5. Gao X, Zhao L, Liu S, Li Y, Xia S, Chen D, et al. γ-6-Phosphogluconolactone, a Byproduct of the Oxidative Pentose Phosphate Pathway, Contributes to AMPK Activation through Inhibition of PP2A. Mol Cell. 2019;76:857-871.e9 pubmed publisher
  6. Wang X, Wang R, Luo M, Li C, Wang H, Huan C, et al. (DEAD)-box RNA helicase 3 modulates NF-κB signal pathway by controlling the phosphorylation of PP2A-C subunit. Oncotarget. 2017;8:33197-33213 pubmed publisher
  7. He X, Li Z, Rizak J, Wu S, Wang Z, He R, et al. Resveratrol Attenuates Formaldehyde Induced Hyperphosphorylation of Tau Protein and Cytotoxicity in N2a Cells. Front Neurosci. 2016;10:598 pubmed publisher
  8. Yin Y, Gao D, Wang Y, Wang Z, Wang X, Ye J, et al. Tau accumulation induces synaptic impairment and memory deficit by calcineurin-mediated inactivation of nuclear CaMKIV/CREB signaling. Proc Natl Acad Sci U S A. 2016;113:E3773-81 pubmed publisher
  9. Jeong A, Han S, Lee S, Su Park J, Lu Y, Yu S, et al. Patient derived mutation W257G of PPP2R1A enhances cancer cell migration through SRC-JNK-c-Jun pathway. Sci Rep. 2016;6:27391 pubmed publisher
  10. An X, Zhao Z, Luo Y, Zhang R, Tang X, Hao D, et al. Netrin-1 suppresses the MEK/ERK pathway and ITGB4 in pancreatic cancer. Oncotarget. 2016;7:24719-33 pubmed publisher
  11. Li Z, Liu Y, Liu X, Xue Y, Wang P, Liu L. Low-dose endothelial monocyte-activating polypeptide-II increases permeability of blood-tumor barrier via a PKC-ζ/PP2A-dependent signaling mechanism. Exp Cell Res. 2015;331:257-66 pubmed publisher
  12. Darna M, Beckmann J, Gipson C, Bardo M, Dwoskin L. Effect of environmental enrichment on dopamine and serotonin transporters and glutamate neurotransmission in medial prefrontal and orbitofrontal cortex. Brain Res. 2015;1599:115-25 pubmed publisher
  13. Du H, Wu K, Didoronkute A, Levy M, Todi N, Shchelokova A, et al. MID1 catalyzes the ubiquitination of protein phosphatase 2A and mutations within its Bbox1 domain disrupt polyubiquitination of alpha4 but not of PP2Ac. PLoS ONE. 2014;9:e107428 pubmed publisher
  14. Amsailale R, Beyaert M, Smal C, Janssens V, Van Den Neste E, Bontemps F. Protein phosphatase 2A regulates deoxycytidine kinase activity via Ser-74 dephosphorylation. FEBS Lett. 2014;588:727-32 pubmed publisher
  15. Yang W, Wang X, Duan C, Lu L, Yang H. Alpha-synuclein overexpression increases phospho-protein phosphatase 2A levels via formation of calmodulin/Src complex. Neurochem Int. 2013;63:180-94 pubmed publisher
  16. Degrande S, Little S, Nixon D, Wright P, Snyder J, Dun W, et al. Molecular mechanisms underlying cardiac protein phosphatase 2A regulation in heart. J Biol Chem. 2013;288:1032-46 pubmed publisher
  17. Schweitzer G, Arias E, Cartee G. Sustained postexercise increases in AS160 Thr642 and Ser588 phosphorylation in skeletal muscle without sustained increases in kinase phosphorylation. J Appl Physiol (1985). 2012;113:1852-61 pubmed publisher