This is a Validated Antibody Database (VAD) review about human PPP1R12A, based on 16 published articles (read how Labome selects the articles), using PPP1R12A antibody in all methods. It is aimed to help Labome visitors find the most suited PPP1R12A antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
PPP1R12A synonym: M130; MBS; MYPT1

Santa Cruz Biotechnology
mouse monoclonal
  • immunocytochemistry; human; loading ...; fig 5b
Santa Cruz Biotechnology PPP1R12A antibody (Santa Cruz, sc-514261) was used in immunocytochemistry on human samples (fig 5b). Nat Commun (2021) ncbi
mouse monoclonal
  • immunoprecipitation; mouse; 1:50; loading ...; fig 8g
Santa Cruz Biotechnology PPP1R12A antibody (Santa, sc-514261) was used in immunoprecipitation on mouse samples at 1:50 (fig 8g). J Cell Biol (2019) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot; mouse; 1:500; loading ...; fig 1f
Cell Signaling Technology PPP1R12A antibody (Cell Signaling, 2634) was used in western blot on mouse samples at 1:500 (fig 1f). Nat Commun (2022) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:500; loading ...; fig 4f
Cell Signaling Technology PPP1R12A antibody (CST, 2634) was used in western blot on mouse samples at 1:500 (fig 4f). Nat Commun (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:500; loading ...; fig 4f
Cell Signaling Technology PPP1R12A antibody (CST, 5163) was used in western blot on mouse samples at 1:500 (fig 4f). Nat Commun (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 5c
  • western blot; human; loading ...; fig 7d
Cell Signaling Technology PPP1R12A antibody (Cell Signaling, 2634) was used in western blot on mouse samples (fig 5c) and in western blot on human samples (fig 7d). Nat Commun (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 6e
Cell Signaling Technology PPP1R12A antibody (Cell Signaling, 5163) was used in western blot on mouse samples (fig 6e). Nat Commun (2021) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; fig 3e
Cell Signaling Technology PPP1R12A antibody (Cell signaling, 3040) was used in western blot on human samples at 1:1000 (fig 3e). Antioxidants (Basel) (2021) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; fig 3e
Cell Signaling Technology PPP1R12A antibody (Cell signaling, 2634) was used in western blot on human samples at 1:1000 (fig 3e). Antioxidants (Basel) (2021) ncbi
domestic rabbit monoclonal (D6C1)
  • western blot; human; 1:1000; loading ...; fig 3c
Cell Signaling Technology PPP1R12A antibody (Cell Signaling, 8574) was used in western blot on human samples at 1:1000 (fig 3c). Cell Death Dis (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 1a
Cell Signaling Technology PPP1R12A antibody (CST, 4563) was used in western blot on mouse samples at 1:1000 (fig 1a). elife (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 7a
Cell Signaling Technology PPP1R12A antibody (Cell Signaling, 5163S) was used in western blot on human samples at 1:1000 (fig 7a). PLoS ONE (2018) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 7a
Cell Signaling Technology PPP1R12A antibody (Cell Signaling, 2634S) was used in western blot on human samples at 1:1000 (fig 7a). PLoS ONE (2018) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 2b
  • western blot; mouse; loading ...; fig 2a, 3a
Cell Signaling Technology PPP1R12A antibody (Cell Signaling, 5163) was used in western blot on human samples (fig 2b) and in western blot on mouse samples (fig 2a, 3a). J Biol Chem (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig s7a
In order to elucidate the role of IP3R in regulating blood pressure in vivo, Cell Signaling Technology PPP1R12A antibody (Cell signaling, 2634P) was used in western blot on mouse samples (fig s7a). JCI Insight (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 2b
In order to examine the role of myocardin-related transcription factor overexpression in cell migration, Cell Signaling Technology PPP1R12A antibody (Cell Signaling, 5163) was used in western blot on mouse samples (fig 2b). Oncotarget (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...
In order to report the O-linked N-acetylglucosamine glycoproteome observed in human T cells, Cell Signaling Technology PPP1R12A antibody (Cell Signaling, 2634) was used in western blot on human samples . J Immunol (2016) ncbi
domestic rabbit polyclonal
  • western blot; guinea pig; fig 7
In order to assess the independence of secretion of beta-1 integrins in airway wall and focal adhesions proteins down regulation from airway hyperresponsiveness in asthma model, Cell Signaling Technology PPP1R12A antibody (Cell Signaling, 5163P) was used in western blot on guinea pig samples (fig 7). J Cell Biochem (2016) ncbi
domestic rabbit monoclonal (D6C1)
  • western blot; human; 1:1000; loading ...; fig 5f
Cell Signaling Technology PPP1R12A antibody (Cell Signalling, 8574) was used in western blot on human samples at 1:1000 (fig 5f). Nat Commun (2015) ncbi
domestic rabbit monoclonal (D6C1)
  • western blot; human
In order to evaluate the effect of tumor necrosis factor on claudin-5 endothelial tight junction barriers, Cell Signaling Technology PPP1R12A antibody (Cell Signaling, 8574) was used in western blot on human samples . PLoS ONE (2015) ncbi
BD Biosciences
mouse monoclonal (20/MYPT1)
  • western blot; mouse; 1:1000; loading ...; fig 2d
In order to propose that simvastatin inhibits RhoA/ROCK activity in the chronic hypoxia-exposed lung, BD Biosciences PPP1R12A antibody (BD Biosciences, 612164) was used in western blot on mouse samples at 1:1000 (fig 2d). Am J Physiol Lung Cell Mol Physiol (2016) ncbi
Articles Reviewed
  1. Takahashi H, Yang G, Yoneshiro T, Abe Y, Ito R, Yang C, et al. MYPT1-PP1β phosphatase negatively regulates both chromatin landscape and co-activator recruitment for beige adipogenesis. Nat Commun. 2022;13:5715 pubmed publisher
  2. Jungwirth U, van Weverwijk A, Evans R, Jenkins L, Vicente D, Alexander J, et al. Impairment of a distinct cancer-associated fibroblast population limits tumour growth and metastasis. Nat Commun. 2021;12:3516 pubmed publisher
  3. Nakatani T, Tsujimoto K, Park J, Jo T, Kimura T, Hayama Y, et al. The lysosomal Ragulator complex plays an essential role in leukocyte trafficking by activating myosin II. Nat Commun. 2021;12:3333 pubmed publisher
  4. Chang N, Yeh C, Lin Y, Kuo K, Fong I, Kounis N, et al. Garcinol Attenuates Lipoprotein(a)-Induced Oxidative Stress and Inflammatory Cytokine Production in Ventricular Cardiomyocyte through α7-Nicotinic Acetylcholine Receptor-Mediated Inhibition of the p38 MAPK and NF-κB Signaling Pathways. Antioxidants (Basel). 2021;10: pubmed publisher
  5. Guo S, Chen Y, Yang Y, Zhang X, Ma L, Xue X, et al. TRIB2 modulates proteasome function to reduce ubiquitin stability and protect liver cancer cells against oxidative stress. Cell Death Dis. 2021;12:42 pubmed publisher
  6. Berndsen K, Lis P, Yeshaw W, Wawro P, Nirujogi R, Wightman M, et al. PPM1H phosphatase counteracts LRRK2 signaling by selectively dephosphorylating Rab proteins. elife. 2019;8: pubmed publisher
  7. Mason D, Collins J, Dawahare J, Nguyen T, Lin Y, Voytik Harbin S, et al. YAP and TAZ limit cytoskeletal and focal adhesion maturation to enable persistent cell motility. J Cell Biol. 2019;218:1369-1389 pubmed publisher
  8. Yasuda Yamahara M, Rogg M, Yamahara K, Maier J, Huber T, Schell C. AIF1L regulates actomyosin contractility and filopodial extensions in human podocytes. PLoS ONE. 2018;13:e0200487 pubmed publisher
  9. Hsia H, Hutti J, Baldwin A. Cytosolic DNA Promotes Signal Transducer and Activator of Transcription 3 (STAT3) Phosphorylation by TANK-binding Kinase 1 (TBK1) to Restrain STAT3 Activity. J Biol Chem. 2017;292:5405-5417 pubmed publisher
  10. Lin Q, Zhao G, Fang X, Peng X, Tang H, Wang H, et al. IP3 receptors regulate vascular smooth muscle contractility and hypertension. JCI Insight. 2016;1:e89402 pubmed publisher
  11. Kishi T, Mayanagi T, Iwabuchi S, Akasaka T, Sobue K. Myocardin-related transcription factor A (MRTF-A) activity-dependent cell adhesion is correlated to focal adhesion kinase (FAK) activity. Oncotarget. 2016;7:72113-72130 pubmed publisher
  12. Wong M, Kantores C, Ivanovska J, Jain A, Jankov R. Simvastatin prevents and reverses chronic pulmonary hypertension in newborn rats via pleiotropic inhibition of RhoA signaling. Am J Physiol Lung Cell Mol Physiol. 2016;311:L985-L999 pubmed publisher
  13. Lund P, Elias J, Davis M. Global Analysis of O-GlcNAc Glycoproteins in Activated Human T Cells. J Immunol. 2016;197:3086-3098 pubmed
  14. Álvarez Santos M, Carbajal V, Tellez Jiménez O, Martínez Cordero E, Ruiz V, Hernández Pando R, et al. Airway Hyperresponsiveness in Asthma Model Occurs Independently of Secretion of β1 Integrins in Airway Wall and Focal Adhesions Proteins Down Regulation. J Cell Biochem. 2016;117:2385-96 pubmed publisher
  15. Caporali A, Meloni M, Nailor A, Mitić T, Shantikumar S, Riu F, et al. p75(NTR)-dependent activation of NF-κB regulates microRNA-503 transcription and pericyte-endothelial crosstalk in diabetes after limb ischaemia. Nat Commun. 2015;6:8024 pubmed publisher
  16. Clark P, Kim R, Pober J, Kluger M. Tumor necrosis factor disrupts claudin-5 endothelial tight junction barriers in two distinct NF-κB-dependent phases. PLoS ONE. 2015;10:e0120075 pubmed publisher