This is a Validated Antibody Database (VAD) review about human PPIF, based on 16 published articles (read how Labome selects the articles), using PPIF antibody in all methods. It is aimed to help Labome visitors find the most suited PPIF antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
PPIF synonym: CYP3; CyP-M; Cyp-D; CypD

Abcam
mouse monoclonal (E11AE12BD4)
  • western blot; human; loading ...; fig 2g
Abcam PPIF antibody (Abcam, ab110324) was used in western blot on human samples (fig 2g). elife (2020) ncbi
mouse monoclonal (E11AE12BD4)
  • immunocytochemistry; human; 1:500; loading ...; fig 6d
  • immunohistochemistry; mouse; 1:500; loading ...; fig 1c
  • western blot; mouse; 1:1000; loading ...; fig 1a
Abcam PPIF antibody (Abcam, ab110324) was used in immunocytochemistry on human samples at 1:500 (fig 6d), in immunohistochemistry on mouse samples at 1:500 (fig 1c) and in western blot on mouse samples at 1:1000 (fig 1a). Front Cell Dev Biol (2019) ncbi
mouse monoclonal (E11AE12BD4)
  • immunoprecipitation; rat; loading ...; fig 5c
  • immunocytochemistry; rat; 1:200; loading ...; fig 5a
  • western blot; rat; 1:2000; loading ...; fig 4d
Abcam PPIF antibody (Abcam, ab110324) was used in immunoprecipitation on rat samples (fig 5c), in immunocytochemistry on rat samples at 1:200 (fig 5a) and in western blot on rat samples at 1:2000 (fig 4d). Redox Biol (2019) ncbi
mouse monoclonal (E11AE12BD4)
  • other; human; loading ...; fig 4c
Abcam PPIF antibody (Abcam, ab110324) was used in other on human samples (fig 4c). Cancer Cell (2018) ncbi
mouse monoclonal (E11AE12BD4)
  • western blot; mouse; 1:5000; loading ...; fig s2k
Abcam PPIF antibody (Abcam, ab110324) was used in western blot on mouse samples at 1:5000 (fig s2k). Nature (2017) ncbi
mouse monoclonal (E11AE12BD4)
  • western blot; human; 1:5000; loading ...; fig 2a
Abcam PPIF antibody (Abcam, E11AE12BD4) was used in western blot on human samples at 1:5000 (fig 2a). Nat Commun (2017) ncbi
mouse monoclonal (E11AE12BD4)
  • western blot; mouse; loading ...; fig 6g
In order to test if BGP-15 ameliorate established disease in a mouse model of Duchenne muscular dystrophy, Abcam PPIF antibody (Abcam, ab110324) was used in western blot on mouse samples (fig 6g). Am J Pathol (2016) ncbi
mouse monoclonal (E11AE12BD4)
  • immunohistochemistry - free floating section; mouse; loading ...; fig 3c
  • western blot; mouse; loading ...; fig 3a
In order to use a mitochondrial single-channel patch clamp and cyclophilin D-deficient mice with streptozotocin-induced diabetes to study mitochondrial dysfunction, Abcam PPIF antibody (Abcam, ab110324) was used in immunohistochemistry - free floating section on mouse samples (fig 3c) and in western blot on mouse samples (fig 3a). Diabetes (2016) ncbi
mouse monoclonal (E11AE12BD4)
  • western blot; pigs ; 1:1000; fig 7c
Abcam PPIF antibody (Abcam, ab110324) was used in western blot on pigs samples at 1:1000 (fig 7c). J Am Heart Assoc (2016) ncbi
mouse monoclonal (E11AE12BD4)
  • western blot; mouse; 1:500; fig s6
In order to characterize how mitochondrial Ca(21) uptake through MICU1 regulation dictates tissue regeneration and survival, Abcam PPIF antibody (Abcam, ab110324) was used in western blot on mouse samples at 1:500 (fig s6). Nat Commun (2016) ncbi
mouse monoclonal (E11AE12BD4)
  • western blot; human
In order to characterize the effect of cyclosporine A treatment in a mouse model of lethal mitochondrial myopathy, Abcam PPIF antibody (Abcam, ab110324) was used in western blot on human samples . Hum Mol Genet (2015) ncbi
mouse monoclonal (E11AE12BD4)
  • western blot; mouse
In order to test if NR2B and CypD work together to repair synaptic injury after ischemia, Abcam PPIF antibody (Abcam, ab110324) was used in western blot on mouse samples . Biochim Biophys Acta (2015) ncbi
mouse monoclonal (E11AE12BD4)
  • immunoprecipitation; human; fig 6
  • immunocytochemistry; human; fig 5
  • western blot; human; fig 5
In order to study reprogramming of cells toward a metastatic-like state by p53 psi, a transcriptionally inactive p53 isoform, Abcam PPIF antibody (Abcam, ab110324) was used in immunoprecipitation on human samples (fig 6), in immunocytochemistry on human samples (fig 5) and in western blot on human samples (fig 5). Proc Natl Acad Sci U S A (2014) ncbi
mouse monoclonal (E11AE12BD4)
  • western blot; human; 1:5000
In order to identify E2s that regulate the activation, translocation, and enzymatic functions of Parkin during mitochondrial quality control, Abcam PPIF antibody (Abcam, ab110324) was used in western blot on human samples at 1:5000. J Cell Sci (2014) ncbi
mouse monoclonal (E11AE12BD4)
  • western blot; human; 1:500
Abcam PPIF antibody (Abcam, Ab110324) was used in western blot on human samples at 1:500. FASEB J (2014) ncbi
Santa Cruz Biotechnology
mouse monoclonal (G-9)
  • chromatin immunoprecipitation; human
  • western blot; human
In order to determine if cyclophilin-D regulates mitochondrial gene expression, Santa Cruz Biotechnology PPIF antibody (Santa Cruz, sc-376061) was used in chromatin immunoprecipitation on human samples and in western blot on human samples . FASEB J (2015) ncbi
Articles Reviewed
  1. Colpitts C, Ridewood S, Schneiderman B, Warne J, Tabata K, Ng C, et al. Hepatitis C virus exploits cyclophilin A to evade PKR. elife. 2020;9: pubmed publisher
  2. Zhang Y, Lu P, Liang F, Liufu N, Dong Y, ZHENG J, et al. Cyclophilin D Contributes to Anesthesia Neurotoxicity in the Developing Brain. Front Cell Dev Biol. 2019;7:396 pubmed publisher
  3. Xu T, Ding W, Ao X, Chu X, Wan Q, Wang Y, et al. ARC regulates programmed necrosis and myocardial ischemia/reperfusion injury through the inhibition of mPTP opening. Redox Biol. 2019;20:414-426 pubmed publisher
  4. Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  5. Luongo T, Lambert J, Gross P, Nwokedi M, Lombardi A, Shanmughapriya S, et al. The mitochondrial Na+/Ca2+ exchanger is essential for Ca2+ homeostasis and viability. Nature. 2017;545:93-97 pubmed publisher
  6. Senturk S, Shirole N, Nowak D, Corbo V, Pal D, Vaughan A, et al. Rapid and tunable method to temporally control gene editing based on conditional Cas9 stabilization. Nat Commun. 2017;8:14370 pubmed publisher
  7. Kennedy T, Swiderski K, Murphy K, Gehrig S, Curl C, Chandramouli C, et al. BGP-15 Improves Aspects of the Dystrophic Pathology in mdx and dko Mice with Differing Efficacies in Heart and Skeletal Muscle. Am J Pathol. 2016;186:3246-3260 pubmed publisher
  8. Yan S, Du F, Wu L, Zhang Z, Zhong C, Yu Q, et al. F1F0 ATP Synthase-Cyclophilin D Interaction Contributes to Diabetes-Induced Synaptic Dysfunction and Cognitive Decline. Diabetes. 2016;65:3482-3494 pubmed
  9. Hiemstra J, Lee D, Chakir K, Gutiérrez Aguilar M, Marshall K, Zgoda P, et al. Saxagliptin and Tadalafil Differentially Alter Cyclic Guanosine Monophosphate (cGMP) Signaling and Left Ventricular Function in Aortic-Banded Mini-Swine. J Am Heart Assoc. 2016;5:e003277 pubmed publisher
  10. Antony A, Paillard M, Moffat C, Juskeviciute E, Correnti J, Bolon B, et al. MICU1 regulation of mitochondrial Ca(2+) uptake dictates survival and tissue regeneration. Nat Commun. 2016;7:10955 pubmed publisher
  11. Gineste C, Hernandez A, Ivarsson N, Cheng A, Naess K, Wibom R, et al. Cyclophilin D, a target for counteracting skeletal muscle dysfunction in mitochondrial myopathy. Hum Mol Genet. 2015;24:6580-7 pubmed publisher
  12. Zhang Z, Wang Y, Yan S, Du F, Yan S. NR2B-dependent cyclophilin D translocation suppresses the recovery of synaptic transmission after oxygen-glucose deprivation. Biochim Biophys Acta. 2015;1852:2225-2234 pubmed publisher
  13. Radhakrishnan J, Bazarek S, Chandran B, Gazmuri R. Cyclophilin-D: a resident regulator of mitochondrial gene expression. FASEB J. 2015;29:2734-48 pubmed publisher
  14. Senturk S, Yao Z, Camiolo M, Stiles B, Rathod T, Walsh A, et al. p53? is a transcriptionally inactive p53 isoform able to reprogram cells toward a metastatic-like state. Proc Natl Acad Sci U S A. 2014;111:E3287-96 pubmed publisher
  15. Fiesel F, Moussaud Lamodière E, Ando M, Springer W. A specific subset of E2 ubiquitin-conjugating enzymes regulate Parkin activation and mitophagy differently. J Cell Sci. 2014;127:3488-504 pubmed publisher
  16. Gouspillou G, Sgarioto N, Kapchinsky S, Purves Smith F, Norris B, Pion C, et al. Increased sensitivity to mitochondrial permeability transition and myonuclear translocation of endonuclease G in atrophied muscle of physically active older humans. FASEB J. 2014;28:1621-33 pubmed publisher