This is a Validated Antibody Database (VAD) review about human PLP1, based on 7 published articles (read how Labome selects the articles), using PLP1 antibody in all methods. It is aimed to help Labome visitors find the most suited PLP1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
PLP1 synonym: GPM6C; HLD1; MMPL; PLP; PLP/DM20; PMD; SPG2

Abcam
domestic rabbit monoclonal (EPR23504-106)
  • western blot; mouse; 1:1000; loading ...; fig 3a
Abcam PLP1 antibody (Abcam, ab254363) was used in western blot on mouse samples at 1:1000 (fig 3a). Proc Natl Acad Sci U S A (2022) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; pigs ; 1:500; loading ...; fig 3f, 3g, 3h
Abcam PLP1 antibody (Abcam, ab28486) was used in immunohistochemistry - paraffin section on pigs samples at 1:500 (fig 3f, 3g, 3h). PLoS ONE (2020) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:2000; loading ...; fig 4c
Abcam PLP1 antibody (Abcam, ab28486) was used in western blot on mouse samples at 1:2000 (fig 4c). elife (2020) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 1a
Abcam PLP1 antibody (Abcam, ab28486) was used in western blot on mouse samples (fig 1a). Sci Transl Med (2018) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; rat; 1:500; loading ...; tbl 2
  • western blot; rat; 1:500; loading ...; tbl 2
In order to test if interleukin-1b derived from microglia affects myelination and axon development in lipopolysaccharide-treated cells, Abcam PLP1 antibody (Abcam, ab28486) was used in immunohistochemistry on rat samples at 1:500 (tbl 2) and in western blot on rat samples at 1:500 (tbl 2). J Neuroinflammation (2017) ncbi
domestic rabbit monoclonal (EPR12675(2)(B))
  • immunohistochemistry - paraffin section; rat; 1:2000; loading ...; fig st11
  • immunohistochemistry - paraffin section; mouse; 1:2000; loading ...; fig st11
In order to outline the protocols for antibodies used for immunohistochemical studies, Abcam PLP1 antibody (Abcam, ab183493) was used in immunohistochemistry - paraffin section on rat samples at 1:2000 (fig st11) and in immunohistochemistry - paraffin section on mouse samples at 1:2000 (fig st11). J Toxicol Pathol (2017) ncbi
Santa Cruz Biotechnology
mouse monoclonal (plpc 1)
  • immunohistochemistry - paraffin section; crab eating macaque; 1:100
Santa Cruz Biotechnology PLP1 antibody (Santa Cruz, Sc-58571) was used in immunohistochemistry - paraffin section on crab eating macaque samples at 1:100. J Neuroimmune Pharmacol (2013) ncbi
Articles Reviewed
  1. Guo J, Guo Z, Huang Y, Ma S, Yan B, Pan C, et al. Blockage of MLKL prevents myelin damage in experimental diabetic neuropathy. Proc Natl Acad Sci U S A. 2022;119:e2121552119 pubmed publisher
  2. Swier V, White K, Meyerholz D, Chefdeville A, Khanna R, Sieren J, et al. Validating indicators of CNS disorders in a swine model of neurological disease. PLoS ONE. 2020;15:e0228222 pubmed publisher
  3. Zhou L, Shao C, Xie Y, Wang N, Xu S, Luo B, et al. Gab1 mediates PDGF signaling and is essential to oligodendrocyte differentiation and CNS myelination. elife. 2020;9: pubmed publisher
  4. Ou Yang M, Kurz J, Nomura T, Popovic J, Rajapaksha T, Dong H, et al. Axonal organization defects in the hippocampus of adult conditional BACE1 knockout mice. Sci Transl Med. 2018;10: pubmed publisher
  5. Han Q, Lin Q, Huang P, Chen M, Hu X, Fu H, et al. Microglia-derived IL-1? contributes to axon development disorders and synaptic deficit through p38-MAPK signal pathway in septic neonatal rats. J Neuroinflammation. 2017;14:52 pubmed publisher
  6. Furukawa S, Nagaike M, Ozaki K. Databases for technical aspects of immunohistochemistry. J Toxicol Pathol. 2017;30:79-107 pubmed publisher
  7. Haanstra K, Jagessar S, Bauchet A, Doussau M, Fovet C, Heijmans N, et al. Induction of experimental autoimmune encephalomyelitis with recombinant human myelin oligodendrocyte glycoprotein in incomplete Freund's adjuvant in three non-human primate species. J Neuroimmune Pharmacol. 2013;8:1251-64 pubmed publisher