This is a Validated Antibody Database (VAD) review about human PLIN2, based on 28 published articles (read how Labome selects the articles), using PLIN2 antibody in all methods. It is aimed to help Labome visitors find the most suited PLIN2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
PLIN2 synonym: ADFP; ADRP

Knockout validation
Fitzgerald Industries
  • western blot knockout validation; mouse; loading ...; fig 1b
Fitzgerald Industries PLIN2 antibody (Fitzgerald, 20R-AP002) was used in western blot knockout validation on mouse samples (fig 1b). Cells (2021) ncbi
Abcam
domestic rabbit monoclonal (EPR3713)
  • immunohistochemistry; mouse; 1:200; loading ...
Abcam PLIN2 antibody (Abcam, AB108323) was used in immunohistochemistry on mouse samples at 1:200. elife (2022) ncbi
domestic rabbit monoclonal (EPR3713)
  • immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig 3d
  • western blot; mouse; 1:1000; loading ...; fig 3d
Abcam PLIN2 antibody (Abcam, ab108323) was used in immunohistochemistry - paraffin section on mouse samples at 1:500 (fig 3d) and in western blot on mouse samples at 1:1000 (fig 3d). Front Cell Dev Biol (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 1e
  • western blot; mouse; 1:1000; loading ...; fig 1d
Abcam PLIN2 antibody (Abcam, ab52356) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig 1e) and in western blot on mouse samples at 1:1000 (fig 1d). Antioxidants (Basel) (2021) ncbi
domestic rabbit monoclonal (EPR3713)
  • immunocytochemistry; human; 1:500; loading ...; fig s9a
Abcam PLIN2 antibody (Abcam, ab108323) was used in immunocytochemistry on human samples at 1:500 (fig s9a). Science (2020) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:200; loading ...; fig s5a
  • western blot; mouse; 1:5000; loading ...; fig 3a
Abcam PLIN2 antibody (Abcam, ab78920) was used in immunohistochemistry on mouse samples at 1:200 (fig s5a) and in western blot on mouse samples at 1:5000 (fig 3a). Science (2020) ncbi
domestic rabbit monoclonal (EPR3713)
  • western blot; mouse; loading ...; fig 3a
Abcam PLIN2 antibody (Abcam, ab108323) was used in western blot on mouse samples (fig 3a). Sci Rep (2020) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 7a
Abcam PLIN2 antibody (Abcam, ab78920) was used in western blot on human samples at 1:1000 (fig 7a). elife (2019) ncbi
domestic rabbit monoclonal (EPR3713)
  • western blot; human; loading ...; fig 5a
Abcam PLIN2 antibody (Abcam, ab108323) was used in western blot on human samples (fig 5a). Mol Cell (2017) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human; fig 4
  • western blot; mouse; fig 3
In order to evaluate the contribution of cytosolic lipid droplets to lipid absorption, Abcam PLIN2 antibody (abcam, Ab52356) was used in immunocytochemistry on human samples (fig 4) and in western blot on mouse samples (fig 3). Nutr Metab (Lond) (2016) ncbi
R&D Systems
mouse monoclonal (788620)
  • western blot; human; 1:1000; loading ...; fig 2l
R&D Systems PLIN2 antibody (R&D, MAB7634) was used in western blot on human samples at 1:1000 (fig 2l). Acta Neuropathol (2021) ncbi
mouse monoclonal (788620)
  • western blot; mouse; 1:200; loading ...; fig 1f
R&D Systems PLIN2 antibody (R&D Systems, MAB7634) was used in western blot on mouse samples at 1:200 (fig 1f). Antioxidants (Basel) (2021) ncbi
Invitrogen
domestic rabbit polyclonal
  • immunocytochemistry; mouse; loading ...; fig 5b
Invitrogen PLIN2 antibody (Thermo Fisher, PA1-16972) was used in immunocytochemistry on mouse samples (fig 5b). Nat Commun (2020) ncbi
domestic rabbit polyclonal
In order to study the role of skeletal muscle lipid handling in obese patients with type 2 diabetes, Invitrogen PLIN2 antibody (Thermo Scientific, PA5-25042) was used . PLoS ONE (2015) ncbi
domestic rabbit polyclonal
In order to study lipid acetylation during Chlamydia trachomatis infection, Invitrogen PLIN2 antibody (ThermoFisher Scientific, PA5-25042) was used . Microbiologyopen (2015) ncbi
Novus Biologicals
domestic rabbit polyclonal (G10F5)
  • western blot; human; loading ...; fig 3e
In order to quantify proteins involved in mitochondrial oxidation and glucose and lipid metabolism in skeletal muscle of trained and untrained middle-aged men, Novus Biologicals PLIN2 antibody (Novus Biologicals, NB 110-4087) was used in western blot on human samples (fig 3e). Physiol Res (2016) ncbi
domestic rabbit polyclonal (G10F5)
Novus Biologicals PLIN2 antibody (Novus Biologicals, NB110-40878) was used . J Biol Chem (2015) ncbi
Santa Cruz Biotechnology
mouse monoclonal (B-6)
  • western blot; human; 1:1000; fig 3
Santa Cruz Biotechnology PLIN2 antibody (Santa Cruz Biotechnology, sc-377429) was used in western blot on human samples at 1:1000 (fig 3). PLoS Pathog (2016) ncbi
Fitzgerald Industries
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 2c
Fitzgerald Industries PLIN2 antibody (Fitzgerald Industries, 20R-AP002) was used in immunohistochemistry - paraffin section on mouse samples (fig 2c). J Biol Chem (2022) ncbi
  • immunohistochemistry; mouse; 1:500; loading ...; fig s5a
Fitzgerald Industries PLIN2 antibody (Fitzgerald, 20R-AP002) was used in immunohistochemistry on mouse samples at 1:500 (fig s5a). Sci Rep (2021) ncbi
  • immunohistochemistry; mouse; 1:500; loading ...; fig 2a
Fitzgerald Industries PLIN2 antibody (Fitzgerald, 20R-AP002) was used in immunohistochemistry on mouse samples at 1:500 (fig 2a). Mol Neurodegener (2021) ncbi
  • western blot knockout validation; mouse; loading ...; fig 1b
Fitzgerald Industries PLIN2 antibody (Fitzgerald, 20R-AP002) was used in western blot knockout validation on mouse samples (fig 1b). Cells (2021) ncbi
  • western blot; rat; 1:100; loading ...; fig 9a
Fitzgerald Industries PLIN2 antibody (Fitzgerald Industries Acton, 20R-AP002) was used in western blot on rat samples at 1:100 (fig 9a). Am J Physiol Regul Integr Comp Physiol (2019) ncbi
  • western blot; mouse; fig 5f
Fitzgerald Industries PLIN2 antibody (Fitzgerald Industries, 20R-Ap002) was used in western blot on mouse samples (fig 5f). J Cell Biol (2018) ncbi
  • western blot; mouse; 1:5000; fig 9
Fitzgerald Industries PLIN2 antibody (Fitzgerald Industries International, 20R-AP002) was used in western blot on mouse samples at 1:5000 (fig 9). J Biol Chem (2016) ncbi
  • immunohistochemistry - paraffin section; mouse; 1:1300
Fitzgerald Industries PLIN2 antibody (Fitzgerald Industries International, 20R-AP002) was used in immunohistochemistry - paraffin section on mouse samples at 1:1300. Biol Open (2015) ncbi
  • immunohistochemistry - paraffin section; mouse
Fitzgerald Industries PLIN2 antibody (Fitzgerald Industries, 20R-AP002) was used in immunohistochemistry - paraffin section on mouse samples . Am J Physiol Endocrinol Metab (2014) ncbi
Progen
mouse monoclonal (AP125)
  • immunocytochemistry; human; 1:100; loading ...; fig 2e
Progen PLIN2 antibody (PROGEN, 610102) was used in immunocytochemistry on human samples at 1:100 (fig 2e). Science (2019) ncbi
mouse monoclonal (AP125)
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig st1
  • immunohistochemistry - frozen section; rat; loading ...; fig st1
  • immunohistochemistry - paraffin section; rat; 1:200; loading ...; fig st1
In order to outline the protocols for antibodies used for immunohistochemical studies, Progen PLIN2 antibody (Progen, 610102) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig st1), in immunohistochemistry - frozen section on rat samples (fig st1) and in immunohistochemistry - paraffin section on rat samples at 1:200 (fig st1). J Toxicol Pathol (2017) ncbi
mouse monoclonal (AP125)
  • immunohistochemistry; human; 1:500; loading ...; fig 3b
  • western blot; human; 1:500; loading ...; fig 1b
Progen PLIN2 antibody (Progen, AP 125) was used in immunohistochemistry on human samples at 1:500 (fig 3b) and in western blot on human samples at 1:500 (fig 1b). Int J Obes (Lond) (2017) ncbi
Articles Reviewed
  1. Gao F, Li C, Smith S, Peinado N, Kohbodi G, Tran E, et al. Decoding the IGF1 signaling gene regulatory network behind alveologenesis from a mouse model of bronchopulmonary dysplasia. elife. 2022;11: pubmed publisher
  2. Wang X, Xie C, Libby A, Ranjit S, Levi J, Myakala K, et al. The role of FXR and TGR5 in reversing and preventing progression of Western diet-induced hepatic steatosis, inflammation, and fibrosis in mice. J Biol Chem. 2022;298:102530 pubmed publisher
  3. Nickl B, Qadri F, Bader M. Anti-inflammatory role of Gpnmb in adipose tissue of mice. Sci Rep. 2021;11:19614 pubmed publisher
  4. Zhao J, Lu W, Ren Y, Fu Y, Martens Y, Shue F, et al. Apolipoprotein E regulates lipid metabolism and α-synuclein pathology in human iPSC-derived cerebral organoids. Acta Neuropathol. 2021;142:807-825 pubmed publisher
  5. Shao C, Lou P, Liu R, Bi X, Li G, Yang X, et al. Hormone-Responsive BMP Signaling Expands Myoepithelial Cell Lineages and Prevents Alveolar Precocity in Mammary Gland. Front Cell Dev Biol. 2021;9:691050 pubmed publisher
  6. Claes C, Danhash E, Hasselmann J, Chadarevian J, Shabestari S, England W, et al. Plaque-associated human microglia accumulate lipid droplets in a chimeric model of Alzheimer's disease. Mol Neurodegener. 2021;16:50 pubmed publisher
  7. Choi E, Jeong J, Jang H, Ahn Y, Kim K, An H, et al. Skeletal Lipocalin-2 Is Associated with Iron-Related Oxidative Stress in ob/ob Mice with Sarcopenia. Antioxidants (Basel). 2021;10: pubmed publisher
  8. Griffin J, Bejarano E, Wang X, Greenberg A. Integrated Action of Autophagy and Adipose Tissue Triglyceride Lipase Ameliorates Diet-Induced Hepatic Steatosis in Liver-Specific PLIN2 Knockout Mice. Cells. 2021;10: pubmed publisher
  9. Korovila I, Höhn A, Jung T, Grune T, Ott C. Reduced Liver Autophagy in High-Fat Diet Induced Liver Steatosis in New Zealand Obese Mice. Antioxidants (Basel). 2021;10: pubmed publisher
  10. Bosch M, Sánchez Alvarez M, Fajardo A, Kapetanovic R, Steiner B, Dutra F, et al. Mammalian lipid droplets are innate immune hubs integrating cell metabolism and host defense. Science. 2020;370: pubmed publisher
  11. Ogasawara Y, Cheng J, Tatematsu T, Uchida M, Murase O, Yoshikawa S, et al. Long-term autophagy is sustained by activation of CCTβ3 on lipid droplets. Nat Commun. 2020;11:4480 pubmed publisher
  12. Yang P, Wang Y, Tang W, Sun W, Ma Y, Lin S, et al. Western diet induces severe nonalcoholic steatohepatitis, ductular reaction, and hepatic fibrosis in liver CGI-58 knockout mice. Sci Rep. 2020;10:4701 pubmed publisher
  13. Presby D, Checkley L, Jackman M, Higgins J, Jones K, Giles E, et al. Regular exercise potentiates energetically expensive hepatic de novo lipogenesis during early weight regain. Am J Physiol Regul Integr Comp Physiol. 2019;317:R684-R695 pubmed publisher
  14. Greenwood D, Dos Santos M, Huang S, Russell M, Collinson L, Macrae J, et al. Subcellular antibiotic visualization reveals a dynamic drug reservoir in infected macrophages. Science. 2019;364:1279-1282 pubmed publisher
  15. Yeshaw W, van der Zwaag M, Pinto F, Lahaye L, Faber A, Gómez Sánchez R, et al. Human VPS13A is associated with multiple organelles and influences mitochondrial morphology and lipid droplet motility. elife. 2019;8: pubmed publisher
  16. Xu D, Li Y, Wu L, Li Y, Zhao D, Yu J, et al. Rab18 promotes lipid droplet (LD) growth by tethering the ER to LDs through SNARE and NRZ interactions. J Cell Biol. 2018;217:975-995 pubmed publisher
  17. Zhao Y, Chen Y, Miao G, Zhao H, Qu W, Li D, et al. The ER-Localized Transmembrane Protein EPG-3/VMP1 Regulates SERCA Activity to Control ER-Isolation Membrane Contacts for Autophagosome Formation. Mol Cell. 2017;67:974-989.e6 pubmed publisher
  18. Furukawa S, Nagaike M, Ozaki K. Databases for technical aspects of immunohistochemistry. J Toxicol Pathol. 2017;30:79-107 pubmed publisher
  19. Hirschmugl B, Desoye G, Catalano P, Klymiuk I, Scharnagl H, Payr S, et al. Maternal obesity modulates intracellular lipid turnover in the human term placenta. Int J Obes (Lond). 2017;41:317-323 pubmed publisher
  20. Soayfane Z, Tercé F, Cantiello M, Robenek H, Nauze M, Bézirard V, et al. Exposure to dietary lipid leads to rapid production of cytosolic lipid droplets near the brush border membrane. Nutr Metab (Lond). 2016;13:48 pubmed publisher
  21. Smagris E, Gilyard S, BasuRay S, Cohen J, Hobbs H. Inactivation of Tm6sf2, a Gene Defective in Fatty Liver Disease, Impairs Lipidation but Not Secretion of Very Low Density Lipoproteins. J Biol Chem. 2016;291:10659-76 pubmed publisher
  22. Zayas M, Long G, Madan V, Bartenschlager R. Coordination of Hepatitis C Virus Assembly by Distinct Regulatory Regions in Nonstructural Protein 5A. PLoS Pathog. 2016;12:e1005376 pubmed publisher
  23. Vigelso A, Prats C, Ploug T, Dela F, Helge J. Higher muscle content of perilipin 5 and endothelial lipase protein in trained than untrained middle-aged men. Physiol Res. 2016;65:293-302 pubmed
  24. Goh V, Tan J, Tan B, Seow C, Ong W, Lim Y, et al. Postnatal Deletion of Fat Storage-inducing Transmembrane Protein 2 (FIT2/FITM2) Causes Lethal Enteropathy. J Biol Chem. 2015;290:25686-99 pubmed publisher
  25. Jiang H, Hurt K, Breen K, Stabler S, Allen R, Orlicky D, et al. Sex-specific dysregulation of cysteine oxidation and the methionine and folate cycles in female cystathionine gamma-lyase null mice: a serendipitous model of the methylfolate trap. Biol Open. 2015;4:1154-62 pubmed publisher
  26. Bakke S, Feng Y, Nikolić N, Kase E, Moro C, Stensrud C, et al. Myotubes from severely obese type 2 diabetic subjects accumulate less lipids and show higher lipolytic rate than myotubes from severely obese non-diabetic subjects. PLoS ONE. 2015;10:e0119556 pubmed publisher
  27. Soupene E, Wang D, Kuypers F. Remodeling of host phosphatidylcholine by Chlamydia acyltransferase is regulated by acyl-CoA binding protein ACBD6 associated with lipid droplets. Microbiologyopen. 2015;4:235-251 pubmed publisher
  28. Suburu J, Shi L, Wu J, Wang S, Samuel M, Thomas M, et al. Fatty acid synthase is required for mammary gland development and milk production during lactation. Am J Physiol Endocrinol Metab. 2014;306:E1132-43 pubmed publisher