This is a Validated Antibody Database (VAD) review about human PKM, based on 57 published articles (read how Labome selects the articles), using PKM antibody in all methods. It is aimed to help Labome visitors find the most suited PKM antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
PKM synonym: CTHBP; HEL-S-30; OIP3; PK3; PKM2; TCB; THBP1; p58

Knockout validation
Cell Signaling Technology
domestic rabbit monoclonal (D78A4)
  • western blot knockout validation; mouse; loading ...; fig 4h
Cell Signaling Technology PKM antibody (Cell Signaling, D78A4) was used in western blot knockout validation on mouse samples (fig 4h). Nature (2019) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D78A4)
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 3f
  • immunocytochemistry; human; 1:400; fig s2a
  • western blot; human; 1:1000; fig s3
In order to study the role of pyruvate kinase M2 in diabetic nephropathy, Cell Signaling Technology PKM antibody (Cell Signaling, 4053) was used in western blot knockout validation on mouse samples at 1:1000 (fig 3f), in immunocytochemistry on human samples at 1:400 (fig s2a) and in western blot on human samples at 1:1000 (fig s3). Nat Med (2017) ncbi
Abcam
domestic rabbit polyclonal
  • western blot; human; 1:5000; loading ...; fig 4d
Abcam PKM antibody (Abcam, ab85555) was used in western blot on human samples at 1:5000 (fig 4d). Oncol Lett (2021) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; fig 1l
Abcam PKM antibody (Abcam, ab137852) was used in western blot on human samples at 1:1000 (fig 1l). Int J Biol Sci (2021) ncbi
domestic rabbit monoclonal (EPR10139)
  • immunohistochemistry; human; loading ...; fig s4c
  • western blot; human; 1:1000; loading ...; fig 1e
Abcam PKM antibody (Abcam, ab154816) was used in immunohistochemistry on human samples (fig s4c) and in western blot on human samples at 1:1000 (fig 1e). Cancer Commun (Lond) (2021) ncbi
domestic rabbit monoclonal (EPR10138(B))
  • immunohistochemistry - paraffin section; human; fig 5f
  • western blot; human; loading ...; fig 4g
Abcam PKM antibody (Abcam, ab150377) was used in immunohistochemistry - paraffin section on human samples (fig 5f) and in western blot on human samples (fig 4g). Oncogenesis (2019) ncbi
domestic rabbit monoclonal (EPR10138(B))
  • western blot; human; loading ...; fig 1b
Abcam PKM antibody (Abcam, ab150377) was used in western blot on human samples (fig 1b). Free Radic Biol Med (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (C-11)
  • western blot; human; loading ...; fig 6f
Santa Cruz Biotechnology PKM antibody (Santa Cruz Biotechnology, sc-365684) was used in western blot on human samples (fig 6f). Oncogenesis (2021) ncbi
mouse monoclonal (C-11)
  • western blot; human; loading ...; fig 2b
Santa Cruz Biotechnology PKM antibody (Santa, sc-365684) was used in western blot on human samples (fig 2b). Autophagy (2019) ncbi
mouse monoclonal (C-11)
  • other; human; loading ...; fig 3g
Santa Cruz Biotechnology PKM antibody (Santa Cruz, sc-365684) was used in other on human samples (fig 3g). Nature (2019) ncbi
mouse monoclonal (C-11)
  • western blot; mouse; 1:1000; loading ...; fig 4e
Santa Cruz Biotechnology PKM antibody (SantaCruz, sc-365684) was used in western blot on mouse samples at 1:1000 (fig 4e). Cell Signal (2018) ncbi
mouse monoclonal (C-11)
  • western blot; human; 1:2000; loading ...; fig 5b
Santa Cruz Biotechnology PKM antibody (Santa Cruz Biotechnology, sc-365684) was used in western blot on human samples at 1:2000 (fig 5b). Am J Cancer Res (2017) ncbi
mouse monoclonal (C-11)
  • western blot; human; 1:500; fig 2
Santa Cruz Biotechnology PKM antibody (santa Cruz, sc-365684) was used in western blot on human samples at 1:500 (fig 2). Nat Cell Biol (2015) ncbi
Novus Biologicals
domestic rabbit polyclonal (13B3)
  • immunocytochemistry; human; 1:200; loading ...; fig s4i
Novus Biologicals PKM antibody (Novus Biologicals, NBP1-48308) was used in immunocytochemistry on human samples at 1:200 (fig s4i). Science (2018) ncbi
domestic rabbit polyclonal (R34-34)
Novus Biologicals PKM antibody (novus Biologicals, NBP2-14833) was used . Nat Cell Biol (2015) ncbi
Invitrogen
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:200; loading ...; fig 3d
In order to report that hepatocytes rapidly upregulate NF- kB and Smad2/3 activity, and repress Notch signaling, Invitrogen PKM antibody (Life Technologies, PA5-23034) was used in immunohistochemistry on mouse samples at 1:200 (fig 3d). Sci Rep (2017) ncbi
R&D Systems
domestic sheep polyclonal
  • immunohistochemistry; mouse; loading ...; fig 2c
  • western blot; mouse; loading ...; fig 2d
R&D Systems PKM antibody (R&D, AF7244) was used in immunohistochemistry on mouse samples (fig 2c) and in western blot on mouse samples (fig 2d). Theranostics (2022) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D78A4)
  • flow cytometry; mouse; loading ...; fig 1b
Cell Signaling Technology PKM antibody (Cell Signaling, 4053s) was used in flow cytometry on mouse samples (fig 1b). Redox Biol (2022) ncbi
domestic rabbit monoclonal (D78A4)
  • western blot; human; loading ...; fig s4b, s4c
Cell Signaling Technology PKM antibody (CST, 4053T) was used in western blot on human samples (fig s4b, s4c). J Exp Clin Cancer Res (2022) ncbi
domestic rabbit monoclonal (D78A4)
  • western blot; human; loading ...; fig 1c
Cell Signaling Technology PKM antibody (Cell Signaling, 4053) was used in western blot on human samples (fig 1c). Cell Death Dis (2022) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 3a
Cell Signaling Technology PKM antibody (Cell Signaling Technology, 3198S) was used in western blot on mouse samples at 1:1000 (fig 3a). Cancers (Basel) (2021) ncbi
domestic rabbit monoclonal (D30G6)
  • western blot; human; 1:1000; fig s2
Cell Signaling Technology PKM antibody (Cell Signaling Technology, 7067) was used in western blot on human samples at 1:1000 (fig s2). Int J Biol Sci (2021) ncbi
domestic rabbit monoclonal (D78A4)
  • western blot; mouse; loading ...; fig 3a
  • western blot; human; loading ...; fig 2a, 2e, s2k
Cell Signaling Technology PKM antibody (Cell Signaling, 4053) was used in western blot on mouse samples (fig 3a) and in western blot on human samples (fig 2a, 2e, s2k). Protein Cell (2021) ncbi
domestic rabbit monoclonal (C103A3)
  • western blot; mouse; 1:1000; loading ...; fig s8d
Cell Signaling Technology PKM antibody (Cell Signaling, 3190) was used in western blot on mouse samples at 1:1000 (fig s8d). Nat Commun (2021) ncbi
domestic rabbit monoclonal (D78A4)
  • western blot; human; 1:1000; loading ...; fig 4f
Cell Signaling Technology PKM antibody (Cell Signaling Technology, 4053) was used in western blot on human samples at 1:1000 (fig 4f). J Gene Med (2021) ncbi
domestic rabbit monoclonal (D78A4)
  • RNA immunoprecipitation; human; loading ...; fig 2b
  • immunohistochemistry - paraffin section; human; fig 7j
  • chromatin immunoprecipitation; human; loading ...; fig 5f
  • immunoprecipitation; human; 1:100; loading ...; fig 2f
  • immunocytochemistry; human; loading ...; fig 3a
  • western blot; human; 1:1000; loading ...; fig 5g
Cell Signaling Technology PKM antibody (CST, 4053S) was used in RNA immunoprecipitation on human samples (fig 2b), in immunohistochemistry - paraffin section on human samples (fig 7j), in chromatin immunoprecipitation on human samples (fig 5f), in immunoprecipitation on human samples at 1:100 (fig 2f), in immunocytochemistry on human samples (fig 3a) and in western blot on human samples at 1:1000 (fig 5g). Nat Commun (2021) ncbi
domestic rabbit monoclonal (D78A4)
  • western blot; mouse; 1:1000; loading ...; fig 7d
Cell Signaling Technology PKM antibody (Cell Signaling Technology, 4053S) was used in western blot on mouse samples at 1:1000 (fig 7d). Exp Eye Res (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 7d
Cell Signaling Technology PKM antibody (Cell Signaling Technology, 3827S) was used in western blot on mouse samples at 1:1000 (fig 7d). Exp Eye Res (2021) ncbi
domestic rabbit monoclonal (D78A4)
  • western blot; human; 1:1000; loading ...; fig 4d
Cell Signaling Technology PKM antibody (Cell Signalling, D78A4) was used in western blot on human samples at 1:1000 (fig 4d). BMC Cancer (2021) ncbi
domestic rabbit monoclonal (D78A4)
  • immunohistochemistry; mouse; 1:200; loading ...; fig s4h
  • western blot; mouse; 1:2000; loading ...; fig s4g
Cell Signaling Technology PKM antibody (CST, 4053) was used in immunohistochemistry on mouse samples at 1:200 (fig s4h) and in western blot on mouse samples at 1:2000 (fig s4g). Nat Commun (2020) ncbi
domestic rabbit monoclonal (D78A4)
  • western blot; human; loading ...; fig 4j
Cell Signaling Technology PKM antibody (CST, 4053) was used in western blot on human samples (fig 4j). Sci Adv (2020) ncbi
domestic rabbit monoclonal (D78A4)
  • proximity ligation assay; mouse; loading ...; fig 3e
  • western blot; mouse; 1:1000; loading ...; fig 3d
Cell Signaling Technology PKM antibody (Cell Signaling, 4053) was used in proximity ligation assay on mouse samples (fig 3e) and in western blot on mouse samples at 1:1000 (fig 3d). Nat Commun (2020) ncbi
domestic rabbit monoclonal (D30G6)
  • western blot; mouse; 1:1000; loading ...; fig 4d
Cell Signaling Technology PKM antibody (Cell Signaling, 7067) was used in western blot on mouse samples at 1:1000 (fig 4d). Nat Commun (2020) ncbi
domestic rabbit monoclonal (C103A3)
  • western blot; human; loading ...; fig 1d
Cell Signaling Technology PKM antibody (CST, C103A3) was used in western blot on human samples (fig 1d). Nature (2020) ncbi
domestic rabbit monoclonal (D78A4)
  • western blot; human; 1:1000; loading ...; fig s8
Cell Signaling Technology PKM antibody (Cell Signaling, 4053) was used in western blot on human samples at 1:1000 (fig s8). J Biomed Sci (2020) ncbi
domestic rabbit monoclonal (D78A4)
  • western blot; mouse; loading ...; fig s10b
Cell Signaling Technology PKM antibody (Cell Signaling Technology, 4053) was used in western blot on mouse samples (fig s10b). Science (2019) ncbi
domestic rabbit monoclonal (C103A3)
  • western blot; human; loading ...; fig s4a
Cell Signaling Technology PKM antibody (Cell Signaling, 3190S) was used in western blot on human samples (fig s4a). Cell (2019) ncbi
domestic rabbit monoclonal (D78A4)
  • western blot knockout validation; mouse; loading ...; fig 4h
Cell Signaling Technology PKM antibody (Cell Signaling, D78A4) was used in western blot knockout validation on mouse samples (fig 4h). Nature (2019) ncbi
domestic rabbit monoclonal (D30G6)
  • western blot; mouse; loading ...; fig 4h, ef6c
Cell Signaling Technology PKM antibody (Cell Signaling, D30G6) was used in western blot on mouse samples (fig 4h, ef6c). Nature (2019) ncbi
domestic rabbit monoclonal (D78A4)
  • other; human; loading ...; fig 4c
Cell Signaling Technology PKM antibody (Cell Signaling, 4053) was used in other on human samples (fig 4c). Cancer Cell (2018) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; fig 2a
Cell Signaling Technology PKM antibody (Cell Signaling, 3198) was used in western blot on human samples at 1:1000 (fig 2a). Nature (2018) ncbi
domestic rabbit monoclonal (D78A4)
  • western blot; human; fig 2g
Cell Signaling Technology PKM antibody (Cell Signaling, 4053) was used in western blot on human samples (fig 2g). Nature (2017) ncbi
domestic rabbit monoclonal (D78A4)
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 3f
  • immunocytochemistry; human; 1:400; fig s2a
  • western blot; human; 1:1000; fig s3
In order to study the role of pyruvate kinase M2 in diabetic nephropathy, Cell Signaling Technology PKM antibody (Cell Signaling, 4053) was used in western blot knockout validation on mouse samples at 1:1000 (fig 3f), in immunocytochemistry on human samples at 1:400 (fig s2a) and in western blot on human samples at 1:1000 (fig s3). Nat Med (2017) ncbi
domestic rabbit monoclonal (D30G6)
  • western blot; human; 1:1000; loading ...; fig 1d
In order to study the role of pyruvate kinase M2 in diabetic nephropathy, Cell Signaling Technology PKM antibody (Cell Signaling, 7067) was used in western blot on human samples at 1:1000 (fig 1d). Nat Med (2017) ncbi
domestic rabbit monoclonal (C103A3)
  • western blot; human; fig 5f
Cell Signaling Technology PKM antibody (Cell Signaling, 3190) was used in western blot on human samples (fig 5f). Sci Rep (2017) ncbi
domestic rabbit monoclonal (D78A4)
  • western blot; human; fig 5f
Cell Signaling Technology PKM antibody (Cell Signaling, 4053) was used in western blot on human samples (fig 5f). Sci Rep (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 6a
In order to examine whether proteins of energy metabolism can be used as biomarkers of inflammatory myopathies, Cell Signaling Technology PKM antibody (Cell Signaling, 3827) was used in western blot on human samples at 1:1000 (fig 6a). J Transl Med (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 3g
In order to test if LKB1 mutations contribute to cervical cancer initiation and progress, Cell Signaling Technology PKM antibody (Cell signaling, 3198) was used in western blot on mouse samples (fig 3g). Oncogene (2017) ncbi
domestic rabbit monoclonal (D78A4)
  • western blot; human; fig 3
Cell Signaling Technology PKM antibody (Cell Signaling, D78A4) was used in western blot on human samples (fig 3). Sci Rep (2016) ncbi
domestic rabbit monoclonal (C103A3)
  • western blot; human; fig 3
Cell Signaling Technology PKM antibody (Cell Signaling, C103A3) was used in western blot on human samples (fig 3). Sci Rep (2016) ncbi
domestic rabbit monoclonal (C103A3)
  • western blot; human; 1:1000; loading ...; fig 3b
In order to examine the effect of ghrelin in human Sertoli cells metabolism, Cell Signaling Technology PKM antibody (Cell Signaling, 3190) was used in western blot on human samples at 1:1000 (fig 3b). Mol Cell Endocrinol (2016) ncbi
domestic rabbit monoclonal (D78A4)
  • western blot; human; loading ...; fig 2a
Cell Signaling Technology PKM antibody (Cell Signaling, 4053) was used in western blot on human samples (fig 2a). Cell Biochem Biophys (2016) ncbi
domestic rabbit monoclonal (D30G6)
  • western blot; human; loading ...; fig 2a
Cell Signaling Technology PKM antibody (Cell Signaling, 7067) was used in western blot on human samples (fig 2a). Cell Biochem Biophys (2016) ncbi
domestic rabbit monoclonal (D78A4)
  • immunocytochemistry; mouse; 1:100
Cell Signaling Technology PKM antibody (CST, 4053) was used in immunocytochemistry on mouse samples at 1:100. Nat Commun (2016) ncbi
domestic rabbit monoclonal (D78A4)
  • western blot; human; 1:1000; fig 5
Cell Signaling Technology PKM antibody (Cell Signaling, 4053S) was used in western blot on human samples at 1:1000 (fig 5). Nat Commun (2016) ncbi
domestic rabbit monoclonal (D78A4)
  • western blot; mouse; fig st1
Cell Signaling Technology PKM antibody (Cell Signaling, 4053) was used in western blot on mouse samples (fig st1). Liver Int (2016) ncbi
domestic rabbit monoclonal (D78A4)
  • immunoprecipitation; human; fig 2
  • western blot; human; fig 3
In order to study interplay in autophagy regulation between transglutaminase type 2 and pyruvate kinase isoenzyme M2, Cell Signaling Technology PKM antibody (Cell Signalling, D78A4) was used in immunoprecipitation on human samples (fig 2) and in western blot on human samples (fig 3). Oncotarget (2015) ncbi
domestic rabbit monoclonal (D78A4)
  • western blot; mouse; fig 4
Cell Signaling Technology PKM antibody (Cell Signaling, 4053) was used in western blot on mouse samples (fig 4). elife (2015) ncbi
domestic rabbit monoclonal (D30G6)
  • western blot; human; 1:1000; fig 3e
Cell Signaling Technology PKM antibody (Cell Signaling, 7067) was used in western blot on human samples at 1:1000 (fig 3e). Cell Death Dis (2015) ncbi
domestic rabbit monoclonal (C103A3)
  • western blot; human; 1:1000; fig s11
Cell Signaling Technology PKM antibody (cell Signaling Tech, 3190S) was used in western blot on human samples at 1:1000 (fig s11). PLoS Genet (2015) ncbi
domestic rabbit monoclonal (D78A4)
  • immunoprecipitation; human; fig 1c
  • western blot; human; fig 2d
Cell Signaling Technology PKM antibody (Cell Signaling, 4053) was used in immunoprecipitation on human samples (fig 1c) and in western blot on human samples (fig 2d). Biochem Biophys Res Commun (2015) ncbi
domestic rabbit monoclonal (D78A4)
  • western blot; mouse; 1:1000; fig s9
Cell Signaling Technology PKM antibody (Cell Signaling, 4053) was used in western blot on mouse samples at 1:1000 (fig s9). Nat Commun (2015) ncbi
domestic rabbit monoclonal (D78A4)
  • western blot; human; fig 7
In order to study ectosome-mediated trafficking in fibroblasts, Cell Signaling Technology PKM antibody (Cell Signaling Technology, 4053S) was used in western blot on human samples (fig 7). Biochim Biophys Acta (2015) ncbi
domestic rabbit monoclonal (D78A4)
  • western blot; mouse; fig 3
Cell Signaling Technology PKM antibody (Cell Signaling, 4053) was used in western blot on mouse samples (fig 3). PLoS ONE (2015) ncbi
domestic rabbit monoclonal (C103A3)
  • western blot; human; 1:1500; fig 4e
Cell Signaling Technology PKM antibody (Cell Signaling TECHNOLOGY, 3190) was used in western blot on human samples at 1:1500 (fig 4e). Nat Commun (2015) ncbi
domestic rabbit monoclonal (D78A4)
  • immunoprecipitation; human
  • ELISA; human; 1:1000
  • western blot; human
In order to test if FAK is an intrinsic driver that promotes aerobic glycolysis and tumorigenesis, Cell Signaling Technology PKM antibody (Cell Signaling, 4053) was used in immunoprecipitation on human samples , in ELISA on human samples at 1:1000 and in western blot on human samples . Oncogene (2016) ncbi
domestic rabbit monoclonal (D78A4)
  • immunohistochemistry; human; fig 4
Cell Signaling Technology PKM antibody (Cell Signaling Technologies, D78A4) was used in immunohistochemistry on human samples (fig 4). Nature (2015) ncbi
domestic rabbit monoclonal (D78A4)
  • immunohistochemistry; mouse; 1:300; fig 8
Cell Signaling Technology PKM antibody (Cell Signaling, 4053) was used in immunohistochemistry on mouse samples at 1:300 (fig 8). J Clin Invest (2015) ncbi
domestic rabbit monoclonal (C103A3)
  • western blot; mouse; fig 2d
Cell Signaling Technology PKM antibody (Cell Signaling, C103A3) was used in western blot on mouse samples (fig 2d). Genes Dev (2014) ncbi
Articles Reviewed
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  31. Qi W, Keenan H, Li Q, Ishikado A, Kannt A, Sadowski T, et al. Pyruvate kinase M2 activation may protect against the progression of diabetic glomerular pathology and mitochondrial dysfunction. Nat Med. 2017;23:753-762 pubmed publisher
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  33. Jiang J, Chen X, Liu H, Shao J, Xie R, Gu P, et al. Polypyrimidine Tract-Binding Protein 1 promotes proliferation, migration and invasion in clear-cell renal cell carcinoma by regulating alternative splicing of PKM. Am J Cancer Res. 2017;7:245-259 pubmed
  34. Santacatterina F, Sánchez Aragó M, Catalán García M, Garrabou G, de Arenas C, Grau J, et al. Pyruvate kinase M2 and the mitochondrial ATPase Inhibitory Factor 1 provide novel biomarkers of dermatomyositis: a metabolic link to oncogenesis. J Transl Med. 2017;15:29 pubmed publisher
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