This is a Validated Antibody Database (VAD) review about human PKD1, based on 5 published articles (read how Labome selects the articles), using PKD1 antibody in all methods. It is aimed to help Labome visitors find the most suited PKD1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
PKD1 synonym: PBP; PC1; Pc-1; TRPP1

Santa Cruz Biotechnology
mouse monoclonal (7E12)
  • western blot; human; 1:500; loading ...; fig s13e
Santa Cruz Biotechnology PKD1 antibody (Santa Cruz, sc-130554) was used in western blot on human samples at 1:500 (fig s13e). Nat Commun (2022) ncbi
mouse monoclonal (7E12)
  • western blot; domestic rabbit; 1:50; fig 3
Santa Cruz Biotechnology PKD1 antibody (Santa Cruz Biotechnology, sc130554) was used in western blot on domestic rabbit samples at 1:50 (fig 3). Sci Rep (2015) ncbi
mouse monoclonal (7E12)
  • western blot; dogs; fig 1
  • western blot; mouse; fig 1
In order to analyze Polycystim-1 and its regulation of microtubular cytoskeleton that favors focal adhesions turnover that regulates migration and cell adhesion, Santa Cruz Biotechnology PKD1 antibody (Santa Cruz, sc-130554) was used in western blot on dogs samples (fig 1) and in western blot on mouse samples (fig 1). BMC Cell Biol (2015) ncbi
mouse monoclonal (7E12)
  • western blot; mouse; 1:1000; fig 1
In order to elucidate how polycystin-1 and -2 traffic to cilia, Santa Cruz Biotechnology PKD1 antibody (Santa Cruz, sc-130554) was used in western blot on mouse samples at 1:1000 (fig 1). Nat Commun (2014) ncbi
mouse monoclonal (7E12)
  • western blot; human
Santa Cruz Biotechnology PKD1 antibody (Santa Cruz, 7E12) was used in western blot on human samples . Kidney Int (2014) ncbi
Articles Reviewed
  1. Choudhury M, Li Y, Mistriotis P, Vasconcelos A, DIXON E, Yang J, et al. Kidney epithelial cells are active mechano-biological fluid pumps. Nat Commun. 2022;13:2317 pubmed publisher
  2. Varela A, Piperi C, Sigala F, Agrogiannis G, Davos C, Andri M, et al. Elevated expression of mechanosensory polycystins in human carotid atherosclerotic plaques: association with p53 activation and disease severity. Sci Rep. 2015;5:13461 pubmed publisher
  3. Castelli M, De Pascalis C, Distefano G, Ducano N, Oldani A, Lanzetti L, et al. Regulation of the microtubular cytoskeleton by Polycystin-1 favors focal adhesions turnover to modulate cell adhesion and migration. BMC Cell Biol. 2015;16:15 pubmed publisher
  4. Kim H, Xu H, Yao Q, Li W, Huang Q, Outeda P, et al. Ciliary membrane proteins traffic through the Golgi via a Rabep1/GGA1/Arl3-dependent mechanism. Nat Commun. 2014;5:5482 pubmed publisher
  5. Hogan M, Johnson K, Zenka R, Charlesworth M, Madden B, Mahoney D, et al. Subfractionation, characterization, and in-depth proteomic analysis of glomerular membrane vesicles in human urine. Kidney Int. 2014;85:1225-37 pubmed publisher