This is a Validated Antibody Database (VAD) review about human PKC alpha, based on 72 published articles (read how Labome selects the articles), using PKC alpha antibody in all methods. It is aimed to help Labome visitors find the most suited PKC alpha antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
PKC alpha synonym: AAG6; PKC-alpha; PKCA; PKCI+/-; PKCalpha; PRKACA
Knockout validation
Cell Signaling Technology domestic rabbit polyclonal |
| Cell Signaling Technology PKC alpha antibody (Cell Signaling, 2056) was used in western blot knockout validation on mouse samples (fig 6a) and in western blot on human samples (fig 2a). PLoS Pathog (2017) ncbi |
Cell Signaling Technology domestic rabbit polyclonal |
| In order to clarify the role of protein kinase C in the pathogenesis of RNA toxicity, Cell Signaling Technology PKC alpha antibody (Cell signaling, 9375) was used in western blot knockout validation on mouse samples (fig 2). PLoS ONE (2016) ncbi |
Abcam
domestic rabbit monoclonal (Y124) |
| Abcam PKC alpha antibody (Abcam, AB32376) was used in immunohistochemistry - frozen section on mouse samples at 1:500 (fig 4k). Int J Ophthalmol (2021) ncbi |
domestic rabbit monoclonal (Y124) |
| Abcam PKC alpha antibody (Abcam, ab32376) was used in western blot on mouse samples (fig 2a). Theranostics (2021) ncbi |
domestic rabbit polyclonal |
| Abcam PKC alpha antibody (Abcam, ab59411) was used in western blot on rat samples (fig 4j, 6a). Front Pharmacol (2021) ncbi |
domestic rabbit monoclonal (Y124) |
| Abcam PKC alpha antibody (Abcam, ab32376) was used in western blot on human samples (fig 4f). Theranostics (2021) ncbi |
domestic rabbit monoclonal (EP2608Y) |
| Abcam PKC alpha antibody (Abcam, ab76016) was used in western blot on mouse samples (fig 6e). Biomolecules (2021) ncbi |
domestic rabbit monoclonal (Y124) |
| Abcam PKC alpha antibody (Abcam, ab32376) was used in western blot on mouse samples (fig 6e). Biomolecules (2021) ncbi |
domestic rabbit monoclonal (Y124) |
| Abcam PKC alpha antibody (Abcam, ab32376) was used in immunohistochemistry on mouse samples at 1:2000 (fig s1-1i). elife (2020) ncbi |
domestic rabbit monoclonal (Y124) |
| Abcam PKC alpha antibody (Abcam, ab32376) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig 4a). elife (2018) ncbi |
domestic rabbit monoclonal (Y124) |
| Abcam PKC alpha antibody (Abcam, ab32376) was used in western blot on human samples (fig 5e). J Physiol (2017) ncbi |
domestic rabbit monoclonal (E195) |
| Abcam PKC alpha antibody (Abcam, ab32502) was used in western blot on mouse samples (fig 8a). Cell Death Dis (2016) ncbi |
domestic rabbit monoclonal (EP2608Y) |
| In order to study the contribution of TRPM2 in hyperglycemia-induced oxidative stress, Abcam PKC alpha antibody (Abcam, ab76016) was used in western blot on human samples at 1:500 (fig s3). Sci Rep (2016) ncbi |
domestic rabbit monoclonal (Y124) |
| Abcam PKC alpha antibody (Abcam, AB32376) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig s1a). J Clin Invest (2016) ncbi |
domestic rabbit monoclonal (Y124) |
| Abcam PKC alpha antibody (Abcam, ab32376) was used in western blot on pigs |
domestic rabbit monoclonal (Y124) |
| Abcam PKC alpha antibody (Abcam, ab32376) was used in immunohistochemistry - paraffin section on goldfish samples at 1:200 (fig 4). J Gen Physiol (2015) ncbi |
domestic rabbit monoclonal (Y124) |
| Abcam PKC alpha antibody (Abcam, AB32376) was used in western blot on mouse samples at 1:1000 (fig 5). Cell Stress Chaperones (2015) ncbi |
domestic rabbit monoclonal (EP2608Y) |
| Abcam PKC alpha antibody (Abcam, AB76016) was used in western blot on mouse samples (fig 5). Cell Stress Chaperones (2015) ncbi |
domestic rabbit monoclonal (Y124) |
| Abcam PKC alpha antibody (Abcam, ab32376) was used in immunohistochemistry - frozen section on rat samples at 1:1000 (fig 1a). Brain Struct Funct (2016) ncbi |
domestic rabbit monoclonal (Y124) |
| Abcam PKC alpha antibody (Abcam, ab32376) was used in western blot on mouse samples at 1:500 (fig 4). Neuroreport (2014) ncbi |
Santa Cruz Biotechnology
mouse monoclonal (H-7) |
| Santa Cruz Biotechnology PKC alpha antibody (Santa Cruz, sc-8393) was used in immunohistochemistry - frozen section on mouse samples at 1:100 (fig 2b). Front Neurosci (2021) ncbi |
mouse monoclonal (H-7) |
| Santa Cruz Biotechnology PKC alpha antibody (Santa, sc-8393) was used in immunohistochemistry on mouse samples at 1:50 (fig 2f). elife (2020) ncbi |
mouse monoclonal (MC5) |
| Santa Cruz Biotechnology PKC alpha antibody (SantaCruz, MC5) was used in western blot on mouse samples (fig 6b). Biopharm Drug Dispos (2018) ncbi |
mouse monoclonal (H-7) |
| Santa Cruz Biotechnology PKC alpha antibody (Santa Cruz, SC-8393) was used in immunohistochemistry on Shaw's jird samples at 1:200 (tbl 1). J Comp Neurol (2017) ncbi |
mouse monoclonal (H-7) |
| In order to assess the effects of thrombomodulin on monocyte differentiation, Santa Cruz Biotechnology PKC alpha antibody (Santa Cruz, sc-8393) was used in western blot on human samples (fig 4a). Sci Rep (2016) ncbi |
mouse monoclonal (A-3) |
| Santa Cruz Biotechnology PKC alpha antibody (santa Cruz, sc-17769) was used in immunohistochemistry - frozen section on mouse samples at 1:500 (fig 4). Mol Vis (2016) ncbi |
mouse monoclonal (A-3) |
| In order to analyze the participation in the progression of diabetic kidney disease by decreasing Cdc42-GTP activation in podocytes by NMDA receptors, Santa Cruz Biotechnology PKC alpha antibody (Santa Cruz, sc-17769) was used in western blot on mouse samples at 1:200 (fig 2). J Pathol (2016) ncbi |
mouse monoclonal (H-7) |
| Santa Cruz Biotechnology PKC alpha antibody (Santa Cruz, sc-8393) was used in western blot on mouse samples (fig 5a). Sci Rep (2016) ncbi |
mouse monoclonal (H-7) |
| Santa Cruz Biotechnology PKC alpha antibody (Santa Cruz, sc-8393) was used in immunohistochemistry on mouse samples at 1:500 (fig 3) and in immunohistochemistry on African green monkey samples at 1:500 (fig 3). Neural Plast (2016) ncbi |
mouse monoclonal (H-7) |
| Santa Cruz Biotechnology PKC alpha antibody (Santa Cruz, SC8393) was used in immunohistochemistry on mouse samples at 1:500 (fig 3e). Am J Pathol (2016) ncbi |
mouse monoclonal (H-7) |
| Santa Cruz Biotechnology PKC alpha antibody (Santa Cruz, sc-8393) was used in immunohistochemistry - free floating section on mouse samples (tbl 2). J Comp Neurol (2016) ncbi |
mouse monoclonal (H-7) |
| In order to study alteration of firing properties of mouse retinal ganglion cells due to the gain-of-function nature of Cav1.4 L-type calcium channels, Santa Cruz Biotechnology PKC alpha antibody (Santa Cruz,, sc-8393) was used in immunohistochemistry on mouse samples at 1:500 (fig 8). Channels (Austin) (2015) ncbi |
mouse monoclonal (H-7) |
| Santa Cruz Biotechnology PKC alpha antibody (Santa Cruz, sc-8393) was used in immunocytochemistry on mouse samples at 1:1000 (fig 2). PLoS Biol (2015) ncbi |
mouse monoclonal (H-7) |
| In order to show that Che-1 inhibits mTOR activity in response to stress conditions, Santa Cruz Biotechnology PKC alpha antibody (Santa Cruz, sc-8393) was used in western blot on human samples at 1:250 (fig 1,2,3,4,5,6,7). EMBO J (2015) ncbi |
mouse monoclonal (H-7) |
| Santa Cruz Biotechnology PKC alpha antibody (Santa Cruz, sc-8393) was used in western blot on human samples (fig 1e). J Cell Mol Med (2015) ncbi |
mouse monoclonal (MC5) |
| Santa Cruz Biotechnology PKC alpha antibody (Santa Cruz, sc-80) was used in immunohistochemistry on mouse samples at 1:100 (fig 6H) and in immunohistochemistry on rat samples at 1:100 (fig 5H). J Comp Neurol (2015) ncbi |
mouse monoclonal (H-7) |
| In order to study the effect of melatonin on dendrite formation in the hilar zone of the rat hippocampus, Santa Cruz Biotechnology PKC alpha antibody (Santa Cruz, sc-8393) was used in western blot on rat samples . Int J Mol Sci (2015) ncbi |
mouse monoclonal (H-7) |
| In order to investigate the role of nephrin in beta-cell survival signaling, Santa Cruz Biotechnology PKC alpha antibody (Santa Cruz Biotechnology, sc-8393) was used in western blot on mouse samples . Mol Cell Endocrinol (2015) ncbi |
mouse monoclonal (H-7) |
| Santa Cruz Biotechnology PKC alpha antibody (Santa Cruz Biotech, H7) was used in immunohistochemistry on rat samples at 1:250. Exp Eye Res (2014) ncbi |
mouse monoclonal (H-7) |
| Santa Cruz Biotechnology PKC alpha antibody (Santa Cruz Biotechnology, sc-8393) was used in western blot on mouse samples . Int J Clin Exp Pathol (2014) ncbi |
mouse monoclonal (A-3) |
| Santa Cruz Biotechnology PKC alpha antibody (Santa Cruz Biotechnology, sc-17769) was used in immunohistochemistry on rat samples at 1:200. Eur J Pain (2015) ncbi |
mouse monoclonal (H-7) |
| Santa Cruz Biotechnology PKC alpha antibody (Santa Cruz, sc-8393) was used in immunohistochemistry - paraffin section on human samples at 1:50 and in western blot on human samples at 1:1000. Int J Cancer (2014) ncbi |
mouse monoclonal (H-7) |
| Santa Cruz Biotechnology PKC alpha antibody (Santa Cruz Biotechnology, Sc-8393) was used in immunohistochemistry - frozen section on rat samples at 1:500. J Comp Neurol (2011) ncbi |
mouse monoclonal (MC5) |
| Santa Cruz Biotechnology PKC alpha antibody (Santa Cruz Biotechnology, sc-80) was used in immunohistochemistry - frozen section on African green monkey samples at 1:100. J Comp Neurol (2008) ncbi |
Novus Biologicals
mouse monoclonal (MC5) |
| Novus Biologicals PKC alpha antibody (NOVUS, NB600-201) was used in immunohistochemistry on mouse samples (fig 1g, 3a). iScience (2021) ncbi |
mouse monoclonal (MC5) |
| Novus Biologicals PKC alpha antibody (Novus, NB600-201) was used in immunohistochemistry - frozen section on mouse samples at 1:1000. J Comp Neurol (2007) ncbi |
Invitrogen
domestic rabbit polyclonal |
| Invitrogen PKC alpha antibody (Invitrogen, PA5-17,551) was used in immunohistochemistry on mouse samples at 1:100 (fig 10d). Acta Neuropathol Commun (2021) ncbi |
mouse monoclonal (MC5) |
| In order to test if the alpha1c subunit of L-type voltage-gated calcium channel colocalizes with protein kinase C alpha in the rod bipolar cells in mouse, hamster, rabbit, and dog retinas, Invitrogen PKC alpha antibody (Thermo Fisher, MA1-157) was used in immunohistochemistry on domestic rabbit samples at 1:100 (fig 2), in immunohistochemistry on mouse samples at 1:100 (fig 2), in immunohistochemistry on dogs samples at 1:100 (fig 2) and in immunohistochemistry on hamsters samples at 1:100 (fig 2). Acta Histochem Cytochem (2015) ncbi |
Bio-Rad
mouse monoclonal (133) |
| In order to examine the effects of retinal progenitor cell proliferation on the spatiotemporal differentiation and synaptic development of rods and bipolar cells in early postnatal gestational lead exposure retinas, Bio-Rad PKC alpha antibody (AbD Serotec, MCA1572) was used in immunohistochemistry - frozen section on mouse samples at 1:100 (tbl 2). Mol Vis (2016) ncbi |
Abnova
mouse monoclonal (2F11) |
| In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, Abnova PKC alpha antibody (Abnova, 2F11) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi |
BioLegend
mouse monoclonal (PKC0103) |
| In order to ascertain how claudin-6 is associated with MMP-2 activation and cell invasiveness, BioLegend PKC alpha antibody (Biolegend, 624302) was used in western blot on human samples at 1:200 (fig 4). Exp Cell Res (2017) ncbi |
Cell Signaling Technology
domestic rabbit polyclonal |
| Cell Signaling Technology PKC alpha antibody (Cell Signaling, 2056) was used in immunohistochemistry on mouse samples at 1:200 (fig 2a). J Comp Neurol (2020) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology PKC alpha antibody (Cell Signaling, 2056) was used in western blot on human samples (fig 6b). Cell (2019) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology PKC alpha antibody (Cell Signaling, 9375) was used in western blot on human samples (fig s3c). J Exp Med (2019) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology PKC alpha antibody (Cell Signaling Technology, 9375) was used in western blot on human samples (fig 3e). Cell Metab (2019) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology PKC alpha antibody (Cell Signaling Technology, 2056) was used in western blot on human samples (fig 3e). Cell Metab (2019) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology PKC alpha antibody (Cell Signaling, 2056) was used in other on human samples (fig 4c). Cancer Cell (2018) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology PKC alpha antibody (Cell Signaling, 2056) was used in western blot on human samples at 1:1000 (fig 3b). Cancer Res (2018) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology PKC alpha antibody (Cell Signaling, 2056) was used in western blot on mouse samples at 1:1000 (fig 3). Exp Neurol (2018) ncbi |
domestic rabbit polyclonal |
| In order to study the effect of GNAQ mutations and GNA11/MAPK pathway activation in uveal melanoma, Cell Signaling Technology PKC alpha antibody (Cell Signaling, 2056) was used in western blot on human samples (fig 1b). Cancer Cell (2017) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology PKC alpha antibody (Cell Signaling Technology, 2056) was used in western blot on human samples . Neoplasia (2017) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology PKC alpha antibody (Cell Signaling, 2056) was used in western blot knockout validation on mouse samples (fig 6a) and in western blot on human samples (fig 2a). PLoS Pathog (2017) ncbi |
domestic rabbit polyclonal |
| In order to investigate whether hepatitis C virus has a genetically determined lymphotropism through a co-receptor specific for the infection by lymphotropic hepatitis C virus, Cell Signaling Technology PKC alpha antibody (Cell Signaling, 9375) was used in western blot on human samples at 1:2000 (fig s9b). Nat Commun (2017) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology PKC alpha antibody (Cell Signaling, 2056) was used in western blot on human samples (fig 2b). Oncotarget (2017) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology PKC alpha antibody (Cell Signaling, 9375) was used in western blot on human samples (fig 2b). Oncotarget (2017) ncbi |
domestic rabbit polyclonal |
| In order to study the contribution of TRPM2 in hyperglycemia-induced oxidative stress, Cell Signaling Technology PKC alpha antibody (Cell Signaling, 2056 S) was used in western blot on human samples at 1:500 (fig s3). Sci Rep (2016) ncbi |
domestic rabbit polyclonal |
| In order to identify and characterize alterations in signal transduction that occur during the development Lapatinib resistance, Cell Signaling Technology PKC alpha antibody (Cell Signaling, 9375) was used in western blot on human samples at 1:200 (fig st1). Nat Commun (2016) ncbi |
domestic rabbit polyclonal |
| In order to investigate the contribution of DNA methyltransferase 1 to the epithelial-mesenchymal transition and cancer stem cells, Cell Signaling Technology PKC alpha antibody (Cell Signaling, 2056) was used in western blot on human samples at 1:1000 (fig 3). Neoplasia (2016) ncbi |
domestic rabbit polyclonal |
| In order to clarify the role of protein kinase C in the pathogenesis of RNA toxicity, Cell Signaling Technology PKC alpha antibody (Cell signaling, 9375) was used in western blot knockout validation on mouse samples (fig 2). PLoS ONE (2016) ncbi |
domestic rabbit polyclonal |
| In order to demonstrate that Siglec-E is required for Escherichia coli-induced endocytosis of TLR4, Cell Signaling Technology PKC alpha antibody (Cell Signaling, 9375) was used in flow cytometry on mouse samples (fig 7c) and in western blot on mouse samples (fig 7a). J Immunol (2016) ncbi |
domestic rabbit polyclonal |
| In order to demonstrate that Siglec-E is required for Escherichia coli-induced endocytosis of TLR4, Cell Signaling Technology PKC alpha antibody (Cell Signaling, 2056) was used in western blot on mouse samples (fig 7a). J Immunol (2016) ncbi |
domestic rabbit polyclonal |
| In order to ascertain the mechanism of action of the Rb9 peptide, Cell Signaling Technology PKC alpha antibody (Cell Signaling, 2056) was used in western blot on mouse samples (fig 5e). Peptides (2016) ncbi |
domestic rabbit polyclonal |
| In order to ascertain the mechanism of action of the Rb9 peptide, Cell Signaling Technology PKC alpha antibody (Cell Signaling, 9375) was used in western blot on mouse samples (fig 5e). Peptides (2016) ncbi |
domestic rabbit polyclonal |
| In order to determine the involvement of the CXCL12 system in adapting skeletal muscles to physical exercise, Cell Signaling Technology PKC alpha antibody (Cell Signaling Technology, 9375) was used in western blot on rat samples at 1:1000 (fig 6). Cell Signal (2016) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology PKC alpha antibody (Cell signaling, 2056) was used in western blot on mouse samples at 1:1000 (fig st2). PLoS ONE (2016) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology PKC alpha antibody (Cell Signaling Technology, 9375) was used in western blot on mouse samples at 1:1000 (fig 5). Cell Rep (2016) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology PKC alpha antibody (Cell Signaling Technology, 2056) was used in western blot on mouse samples at 1:1000 (fig 5). Cell Rep (2016) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology PKC alpha antibody (Cell Signaling Tech, 2056P) was used in western blot on human samples (fig s15). Nat Commun (2016) ncbi |
domestic rabbit polyclonal |
| In order to study syndecan-4-mediated podocyte cell-matrix interactions that require N-sulfation of heparan sulfate, Cell Signaling Technology PKC alpha antibody (Cell Signaling, 2056) was used in immunocytochemistry on mouse samples at 1:50 (fig 6). Am J Physiol Renal Physiol (2016) ncbi |
domestic rabbit polyclonal |
| In order to assess the effect of intensive training in combination with marked reduction in training volume on phospholemman expression and phosphorylation at rest and during exercise, Cell Signaling Technology PKC alpha antibody (Cell Signaling Technology, 9375) was used in western blot on human samples (fig 2). Am J Physiol Regul Integr Comp Physiol (2016) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology PKC alpha antibody (Cell Signaling, cs-2056) was used in western blot on mouse samples at 1:1000 (fig 6e). EMBO Mol Med (2016) ncbi |
domestic rabbit polyclonal |
| Cell Signaling Technology PKC alpha antibody (Cell Signaling, cs-9375) was used in western blot on mouse samples at 1:1000 (fig 6e). EMBO Mol Med (2016) ncbi |
MilliporeSigma
domestic rabbit polyclonal |
| MilliporeSigma PKC alpha antibody (Sigma, SAB4502356) was used in immunocytochemistry on mouse samples at 1:200 (fig s10a). Nat Commun (2021) ncbi |
Articles Reviewed
- Chaney S, Mukherjee S, Giddabasappa A, Rueda E, Hamilton W, Johnson J, et al. Increased proliferation of late-born retinal progenitor cells by gestational lead exposure delays rod and bipolar cell differentiation. Mol Vis. 2016;22:1468-1489 pubmed
- Wu Y, Ren D, Chen G. Siglec-E Negatively Regulates the Activation of TLR4 by Controlling Its Endocytosis. J Immunol. 2016;197:3336-3347 pubmed
- Girola N, Matsuo A, Figueiredo C, Massaoka M, Farias C, Arruda D, et al. The Ig VH complementarity-determining region 3-containing Rb9 peptide, inhibits melanoma cells migration and invasion by interactions with Hsp90 and an adhesion G-protein coupled receptor. Peptides. 2016;85:1-15 pubmed publisher
- Simmons A, Bloomsburg S, Billingslea S, Merrill M, Li S, Thomas M, et al. Pou4f2 knock-in Cre mouse: A multifaceted genetic tool for vision researchers. Mol Vis. 2016;22:705-17 pubmed
- Kong J, Liu B, Wu S, Wang Y, Jiang Q, Guo E. Enhancement of interaction of BSEP and HAX-1 on the canalicular membrane of hepatocytes in a mouse model of cholesterol cholelithiasis. Int J Clin Exp Pathol. 2014;7:1644-50 pubmed
- Bayley P, Morgans C. Rod bipolar cells and horizontal cells form displaced synaptic contacts with rods in the outer nuclear layer of the nob2 retina. J Comp Neurol. 2007;500:286-98 pubmed
articles
contribute
- If you are aware of any publication with knockout studies validating a monoclonal or recombinant antibody, either purchased from a supplier or developed by the author(s), please notify us through feedback.
questions and comments