This is a Validated Antibody Database (VAD) review about human PIM2, based on 5 published articles (read how Labome selects the articles), using PIM2 antibody in all methods. It is aimed to help Labome visitors find the most suited PIM2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
PIM2 synonym: serine/threonine-protein kinase pim-2; pim-2 oncogene; pim-2h; proto-oncogene Pim-2 (serine threonine kinase)

Active Motif
rat monoclonal (CHU61)
  • western blot; human; 1:3000; fig 2
Active Motif PIM2 antibody (Active Motif, 61159) was used in western blot on human samples at 1:3000 (fig 2). Mol Cancer (2015) ncbi
Cell Signaling Technology
rabbit monoclonal (D1D2)
  • western blot; human; 1:1000; loading ...; fig 6c
In order to identify glycogen synthase kinase beta and forkhead box P3 as direct PIM targets, Cell Signaling Technology PIM2 antibody (Cell Signaling, 4730) was used in western blot on human samples at 1:1000 (fig 6c). Exp Cell Res (2016) ncbi
rabbit monoclonal (D1D2)
  • immunohistochemistry; human; fig 1f
  • western blot; human; loading ...; fig 1a
Cell Signaling Technology PIM2 antibody (Cell Signaling, 4730) was used in immunohistochemistry on human samples (fig 1f) and in western blot on human samples (fig 1a). Sci Adv (2015) ncbi
rabbit monoclonal (D1D2)
  • western blot; human; fig s3
Cell Signaling Technology PIM2 antibody (Cell Signaling Tech, 4730) was used in western blot on human samples (fig s3). Oncogene (2015) ncbi
rabbit monoclonal (D1D2)
  • western blot; human
Cell Signaling Technology PIM2 antibody (Cell Signaling Technology, 4730) was used in western blot on human samples . Blood (2013) ncbi
Articles Reviewed
  1. Santio N, Salmela M, Arola H, Eerola S, Heino J, Rainio E, et al. The PIM1 kinase promotes prostate cancer cell migration and adhesion via multiple signalling pathways. Exp Cell Res. 2016;342:113-24 pubmed publisher
  2. Kreuz S, Holmes K, Tooze R, Lefevre P. Loss of PIM2 enhances the anti-proliferative effect of the pan-PIM kinase inhibitor AZD1208 in non-Hodgkin lymphomas. Mol Cancer. 2015;14:205 pubmed publisher
  3. Green A, Maciel T, Hospital M, Yin C, Mazed F, Townsend E, et al. Pim kinases modulate resistance to FLT3 tyrosine kinase inhibitors in FLT3-ITD acute myeloid leukemia. Sci Adv. 2015;1:e1500221 pubmed publisher
  4. Moody S, Schinzel A, Singh S, Izzo F, Strickland M, Luo L, et al. PRKACA mediates resistance to HER2-targeted therapy in breast cancer cells and restores anti-apoptotic signaling. Oncogene. 2015;34:2061-71 pubmed publisher
  5. Lu J, Zavorotinskaya T, Dai Y, Niu X, Castillo J, Sim J, et al. Pim2 is required for maintaining multiple myeloma cell growth through modulating TSC2 phosphorylation. Blood. 2013;122:1610-20 pubmed publisher