This is a Validated Antibody Database (VAD) review about human PIK3CG, based on 60 published articles (read how Labome selects the articles), using PIK3CG antibody in all methods. It is aimed to help Labome visitors find the most suited PIK3CG antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
PIK3CG synonym: PI3CG; PI3K; PI3Kgamma; PIK3; p110gamma; p120-PI3K

Knockout validation
Cell Signaling Technology
domestic rabbit monoclonal (D9A5)
  • western blot knockout validation; mouse; 1:1000; fig 2
  • western blot; human; 1:1000; fig 4
Cell Signaling Technology PIK3CG antibody (Cell Signaling, 4263) was used in western blot knockout validation on mouse samples at 1:1000 (fig 2) and in western blot on human samples at 1:1000 (fig 4). J Cell Sci (2016) ncbi
BD Biosciences
mouse monoclonal (17/PI3-Kinase p170)
  • western blot; rat; fig 1d
  • western blot knockout validation; mouse; fig 1d
BD Biosciences PIK3CG antibody (BD, 611046) was used in western blot on rat samples (fig 1d) and in western blot knockout validation on mouse samples (fig 1d). Mol Cell Biol (2011) ncbi
Abcam
domestic rabbit monoclonal (Y388)
  • western blot; human; loading ...; fig 3j
Abcam PIK3CG antibody (Abcam, ab245781) was used in western blot on human samples (fig 3j). Int J Mol Sci (2022) ncbi
domestic rabbit monoclonal (Y388)
  • western blot; human; 1:3,500; loading ...; fig 4f
Abcam PIK3CG antibody (Abcam, ab32089) was used in western blot on human samples at 1:3,500 (fig 4f). Clin Transl Med (2021) ncbi
domestic rabbit monoclonal (Y388)
  • western blot; human; 1:1000; loading ...; fig 7a
Abcam PIK3CG antibody (Abcam, ab32089) was used in western blot on human samples at 1:1000 (fig 7a). Int J Oncol (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 9c
  • western blot; mouse; 1:1000; loading ...; fig 9a
Abcam PIK3CG antibody (Abcam, ab154598) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 9c) and in western blot on mouse samples at 1:1000 (fig 9a). Front Pharmacol (2021) ncbi
mouse monoclonal (OTI4G10)
  • western blot; mouse; 1:2000; loading ...; fig 9a
Abcam PIK3CG antibody (Abcam, ab140307) was used in western blot on mouse samples at 1:2000 (fig 9a). Front Pharmacol (2021) ncbi
domestic rabbit monoclonal (Y388)
  • western blot; human; loading ...; fig 5a
Abcam PIK3CG antibody (Abcam, ab32089) was used in western blot on human samples (fig 5a). Biosci Rep (2019) ncbi
domestic rabbit monoclonal (Y388)
  • western blot; mouse; 1:1000; loading ...; fig 1f
Abcam PIK3CG antibody (Abcam, ab32089) was used in western blot on mouse samples at 1:1000 (fig 1f). BMC Complement Altern Med (2019) ncbi
Invitrogen
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 8a
Invitrogen PIK3CG antibody (Thermo-Fisher, PA5-28070) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 8a). Int J Mol Sci (2021) ncbi
Santa Cruz Biotechnology
mouse monoclonal (D-12)
  • immunohistochemistry; human; loading ...; fig 2a
  • western blot; human; loading ...; fig 3b
Santa Cruz Biotechnology PIK3CG antibody (santa cruz, sc-166365) was used in immunohistochemistry on human samples (fig 2a) and in western blot on human samples (fig 3b). Oncotarget (2016) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D9A5)
  • immunocytochemistry; human; 1:200; loading ...
  • western blot; human; 1:100; loading ...; fig 2a
Cell Signaling Technology PIK3CG antibody (Cell Signaling Technology, 4263S) was used in immunocytochemistry on human samples at 1:200 and in western blot on human samples at 1:100 (fig 2a). Nature (2021) ncbi
mouse monoclonal (6G10)
  • western blot; human; 1:1000; loading ...; fig 3b, 3c
Cell Signaling Technology PIK3CG antibody (Cell Signaling Technology, 13666S) was used in western blot on human samples at 1:1000 (fig 3b, 3c). Cell Biosci (2020) ncbi
domestic rabbit monoclonal (D9A5)
  • western blot; human; loading ...
Cell Signaling Technology PIK3CG antibody (Cell Signaling Technology, 4263s) was used in western blot on human samples . Nat Commun (2020) ncbi
domestic rabbit monoclonal (D9A5)
  • western blot; human; 1:500; loading ...; fig 3a
Cell Signaling Technology PIK3CG antibody (Cell Signaling, 4263) was used in western blot on human samples at 1:500 (fig 3a). Nat Commun (2020) ncbi
domestic rabbit monoclonal (D4E2)
  • western blot; human; loading ...; fig 7a
Cell Signaling Technology PIK3CG antibody (Cell Signaling, 3358) was used in western blot on human samples (fig 7a). Autophagy (2019) ncbi
domestic rabbit monoclonal (D9A5)
  • western blot; mouse; loading ...; fig 5a
Cell Signaling Technology PIK3CG antibody (Cell Signaling Technology, 4263) was used in western blot on mouse samples (fig 5a). EMBO J (2018) ncbi
domestic rabbit monoclonal (D55D5)
  • western blot; human; loading ...; fig s4b
Cell Signaling Technology PIK3CG antibody (Cell Signaling Technology, D55D5) was used in western blot on human samples (fig s4b). Mol Biol Cell (2018) ncbi
domestic rabbit monoclonal (D55D5)
  • western blot; human; fig 5a
Cell Signaling Technology PIK3CG antibody (Cell Signaling, 5405) was used in western blot on human samples (fig 5a). Inflammation (2018) ncbi
domestic rabbit monoclonal (D9A5)
  • western blot; mouse; loading ...; fig 2l
Cell Signaling Technology PIK3CG antibody (Cell Signaling, 4263) was used in western blot on mouse samples (fig 2l). Mol Cell (2017) ncbi
domestic rabbit monoclonal (D55D5)
  • western blot; mouse; 1:1000; loading ...; fig 3c
Cell Signaling Technology PIK3CG antibody (cell signaling, 5405) was used in western blot on mouse samples at 1:1000 (fig 3c). Oncogene (2017) ncbi
domestic rabbit monoclonal (D9A5)
  • western blot; human; loading ...; fig 4
Cell Signaling Technology PIK3CG antibody (Cell signaling, 4263s) was used in western blot on human samples (fig 4). Tumour Biol (2017) ncbi
domestic rabbit monoclonal (D9A5)
  • immunoprecipitation; human; loading ...; fig e3f
  • western blot; human; loading ...; fig e3e
In order to research the effect of polyglutamine tracts on the autophagy process, Cell Signaling Technology PIK3CG antibody (Cell Signalling, 4263) was used in immunoprecipitation on human samples (fig e3f) and in western blot on human samples (fig e3e). Nature (2017) ncbi
domestic rabbit monoclonal (D4E2)
  • western blot; rat; 1:1000; loading ...; fig 5f
Cell Signaling Technology PIK3CG antibody (Cell Signaling, 3358S) was used in western blot on rat samples at 1:1000 (fig 5f). Brain Behav Immun (2017) ncbi
domestic rabbit monoclonal (D4E2)
  • western blot; human; loading ...; fig 1s1f
Cell Signaling Technology PIK3CG antibody (CST, 3358) was used in western blot on human samples (fig 1s1f). elife (2017) ncbi
domestic rabbit monoclonal (D9A5)
  • western blot; human; loading ...; fig 3a
Cell Signaling Technology PIK3CG antibody (cell signalling, 4263) was used in western blot on human samples (fig 3a). Cell Death Dis (2017) ncbi
domestic rabbit monoclonal (D9A5)
  • western blot knockout validation; mouse; 1:1000; fig 2
  • western blot; human; 1:1000; fig 4
Cell Signaling Technology PIK3CG antibody (Cell Signaling, 4263) was used in western blot knockout validation on mouse samples at 1:1000 (fig 2) and in western blot on human samples at 1:1000 (fig 4). J Cell Sci (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human
Cell Signaling Technology PIK3CG antibody (Cell Signalling, 4252) was used in immunohistochemistry - paraffin section on human samples . Respir Res (2016) ncbi
mouse monoclonal (6G10)
  • western blot; human; loading ...; fig 5e
Cell Signaling Technology PIK3CG antibody (Cell signaling, 13666) was used in western blot on human samples (fig 5e). Oncotarget (2016) ncbi
domestic rabbit monoclonal (D9A5)
  • immunoprecipitation; human; loading ...; fig 10
  • immunocytochemistry; human; loading ...; fig 1b
  • western blot; human; loading ...; fig 10
In order to explore how Ehrlichia chaffeensis survives and commandeers the host cell, Cell Signaling Technology PIK3CG antibody (Cell Signaling, 4263) was used in immunoprecipitation on human samples (fig 10), in immunocytochemistry on human samples (fig 1b) and in western blot on human samples (fig 10). Autophagy (2016) ncbi
domestic rabbit monoclonal (D9A5)
  • immunoprecipitation; mouse; loading ...; fig 6a
  • western blot; mouse; loading ...; fig 6a
Cell Signaling Technology PIK3CG antibody (Cell Signaling, 4263) was used in immunoprecipitation on mouse samples (fig 6a) and in western blot on mouse samples (fig 6a). Autophagy (2016) ncbi
domestic rabbit monoclonal (D3Q5B)
  • western blot; human; fig 6
In order to characterize induction of apoptosis in SH-SY5Y human neuroblastoma cells through up regulation of flotillin-2 in the lipid raft and the activation of BDNF/Trkb signaling due to cholesterol overload, Cell Signaling Technology PIK3CG antibody (Cell Signaling Technology, 12402) was used in western blot on human samples (fig 6). Neuroscience (2016) ncbi
domestic rabbit monoclonal (D4E2)
  • western blot; human; loading ...; fig 6a
Cell Signaling Technology PIK3CG antibody (Cell Signaling, 3358) was used in western blot on human samples (fig 6a). Autophagy (2016) ncbi
domestic rabbit monoclonal (D55D5)
  • western blot; human; loading ...; fig 4
In order to find tumor types sensitive to phosphoinositide 3-kinase pathway inhibitors, Cell Signaling Technology PIK3CG antibody (Cell Signaling, 5405) was used in western blot on human samples (fig 4). Oncotarget (2016) ncbi
domestic rabbit monoclonal (D4E2)
  • immunocytochemistry; human; 1:500; fig 5
  • western blot; human; 1:500; fig 5
In order to investigate impairment of autophagy flux and induction of cell death independent of necroptosis and apoptosis by dual PI-3 kinase/mTOR inhibition, Cell Signaling Technology PIK3CG antibody (Cell Signaling, 3358) was used in immunocytochemistry on human samples at 1:500 (fig 5) and in western blot on human samples at 1:500 (fig 5). Oncotarget (2016) ncbi
domestic rabbit monoclonal (D9A5)
  • flow cytometry; human; 1:200; fig e2
  • immunohistochemistry; human; 1:1000; fig e6
In order to study the conversion of phosphatidylinositol 3-phosphate to phosphatidylinositol 4-phosphate at endosomes en route to the plasma membrane, Cell Signaling Technology PIK3CG antibody (Cell Signalling, D9A5) was used in flow cytometry on human samples at 1:200 (fig e2) and in immunohistochemistry on human samples at 1:1000 (fig e6). Nature (2016) ncbi
domestic rabbit monoclonal (D9A5)
  • western blot; mouse; fig 5
Cell Signaling Technology PIK3CG antibody (Cell Signaling Technology, 4263) was used in western blot on mouse samples (fig 5). Aging Cell (2016) ncbi
mouse monoclonal (6G10)
  • western blot; human; 1:1000; loading ...; fig 3c
Cell Signaling Technology PIK3CG antibody (Cell Signaling, 13666) was used in western blot on human samples at 1:1000 (fig 3c). Int J Oncol (2016) ncbi
domestic rabbit monoclonal (D9A5)
  • western blot; rat; fig 2
Cell Signaling Technology PIK3CG antibody (Cell Signaling, 4263s) was used in western blot on rat samples (fig 2). Autophagy (2015) ncbi
domestic rabbit monoclonal (D9A5)
  • western blot; mouse; 1:1000; fig 1
Cell Signaling Technology PIK3CG antibody (Cell Signaling, 4263) was used in western blot on mouse samples at 1:1000 (fig 1). Nat Commun (2015) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:200
In order to elucidate the role of IL-33/IL-33 receptor signaling in mouse models of neuropathic pain, Cell Signaling Technology PIK3CG antibody (Cell Signaling Technology, 4252) was used in western blot on mouse samples at 1:200. FASEB J (2016) ncbi
domestic rabbit monoclonal (D9A5)
  • western blot; human; fig 2
In order to determine stress resistance to breast cancer cells and neuroblastoma by BAG3 function and estrogen receptor alpha that regulates non-canonical autophagy, Cell Signaling Technology PIK3CG antibody (Cell signaling, 4263) was used in western blot on human samples (fig 2). Cell Death Dis (2015) ncbi
domestic rabbit monoclonal (D9A5)
  • western blot; human; 1:1000; fig 1
Cell Signaling Technology PIK3CG antibody (Cell Signaling Tech, 4263) was used in western blot on human samples at 1:1000 (fig 1). Nat Commun (2015) ncbi
domestic rabbit monoclonal (D9A5)
  • western blot; human; fig  3
Cell Signaling Technology PIK3CG antibody (Cell Signaling Technology, 4263) was used in western blot on human samples (fig  3). J Biol Chem (2015) ncbi
domestic rabbit monoclonal (D9A5)
  • western blot; human; fig 1
Cell Signaling Technology PIK3CG antibody (Cell Signaling, 4263) was used in western blot on human samples (fig 1). J Biol Chem (2015) ncbi
domestic rabbit monoclonal (D9A5)
  • western blot; rat
Cell Signaling Technology PIK3CG antibody (Cell Signaling Technology, 4263) was used in western blot on rat samples . Life Sci (2015) ncbi
domestic rabbit monoclonal (D9A5)
  • western blot; mouse; fig s2a
Cell Signaling Technology PIK3CG antibody (Cell Signaling Technologies, 4263) was used in western blot on mouse samples (fig s2a). Mol Cell (2014) ncbi
domestic rabbit monoclonal (D9A5)
  • western blot; mouse; 1:1000; fig s12
Cell Signaling Technology PIK3CG antibody (Cell Signaling, 4263) was used in western blot on mouse samples at 1:1000 (fig s12). PLoS Med (2014) ncbi
domestic rabbit monoclonal (D9A5)
  • western blot; human
Cell Signaling Technology PIK3CG antibody (Cell Signaling Technology, 4263S) was used in western blot on human samples . PLoS ONE (2014) ncbi
domestic rabbit monoclonal (D9A5)
  • western blot; human; 1:1000
In order to identify and characterize the Nrbf2-Beclin 1 interaction, Cell Signaling Technology PIK3CG antibody (Cell Signaling Technology, 4263) was used in western blot on human samples at 1:1000. J Biol Chem (2014) ncbi
domestic rabbit monoclonal (D4E2)
  • western blot; rat; 1:1000
Cell Signaling Technology PIK3CG antibody (Cell Signaling, D4E2) was used in western blot on rat samples at 1:1000. PLoS ONE (2014) ncbi
domestic rabbit monoclonal (D4E2)
  • western blot; mouse; 1:500
Cell Signaling Technology PIK3CG antibody (Cell Signaling Technologies, 3358) was used in western blot on mouse samples at 1:500. Neurobiol Dis (2014) ncbi
domestic rabbit monoclonal (D4E2)
  • western blot; human; 1:1000
Cell Signaling Technology PIK3CG antibody (Cell Signaling, 3358) was used in western blot on human samples at 1:1000. Cell Death Dis (2013) ncbi
BD Biosciences
mouse monoclonal (22/PI3-K)
  • western blot; mouse; 1:1000; loading ...; fig 7a
BD Biosciences PIK3CG antibody (BD Biosciences, 22/PI3-K) was used in western blot on mouse samples at 1:1000 (fig 7a). Nat Commun (2018) ncbi
mouse monoclonal (17/PI3-Kinase p170)
  • western blot; human; loading ...; fig s3a
BD Biosciences PIK3CG antibody (BD Bioscience, 611046) was used in western blot on human samples (fig s3a). Cell (2018) ncbi
mouse monoclonal (4/PI3-Kinase)
  • western blot; human; fig s10
BD Biosciences PIK3CG antibody (BD Biosciences, 610045) was used in western blot on human samples (fig s10). Nat Commun (2016) ncbi
mouse monoclonal (4/PI3-Kinase)
  • immunohistochemistry; human; 1:50; tbl 2
In order to evaluate the reliance on EBV or NF-kappaB signaling instead of B-cell receptor signaling in regards to complete phenotypic characterization of PTLD, BD Biosciences PIK3CG antibody (BD Laboratories, 610046) was used in immunohistochemistry on human samples at 1:50 (tbl 2). Hematol Oncol (2017) ncbi
mouse monoclonal (4/PI3-Kinase)
  • western blot; human; loading ...; fig 1c
BD Biosciences PIK3CG antibody (BD Biosciences, 610045) was used in western blot on human samples (fig 1c). Mar Drugs (2015) ncbi
mouse monoclonal (4/PI3-Kinase)
  • western blot; human; 1:2500; loading ...; fig 5f
BD Biosciences PIK3CG antibody (BD Biosciences, 4/PI3-Kinase) was used in western blot on human samples at 1:2500 (fig 5f). Oncotarget (2015) ncbi
mouse monoclonal (4/PI3-Kinase)
  • other; mouse; 1:2500; fig s1
In order to identify host signaling dynamics upon Burkholderia spp. infection by a reverse-phase protein microarray-based screen, BD Biosciences PIK3CG antibody (BD, 610045) was used in other on mouse samples at 1:2500 (fig s1). Front Microbiol (2015) ncbi
mouse monoclonal (4/PI3-Kinase)
  • western blot; rat; fig 10
BD Biosciences PIK3CG antibody (BD Biosciences, 610045) was used in western blot on rat samples (fig 10). PLoS ONE (2015) ncbi
mouse monoclonal (22/PI3-K)
  • western blot; human; fig 1
BD Biosciences PIK3CG antibody (BD Biosciences, 611342) was used in western blot on human samples (fig 1). J Biol Chem (2015) ncbi
mouse monoclonal (17/PI3-Kinase p170)
  • western blot; human; fig 1
BD Biosciences PIK3CG antibody (BD Biosciences, 611046) was used in western blot on human samples (fig 1). J Biol Chem (2015) ncbi
mouse monoclonal (4/PI3-Kinase)
  • western blot; human; 1:5000
BD Biosciences PIK3CG antibody (BD Bioscience, 610045) was used in western blot on human samples at 1:5000. FASEB J (2013) ncbi
mouse monoclonal (17/PI3-Kinase p170)
  • western blot; rat; fig 1d
  • western blot knockout validation; mouse; fig 1d
BD Biosciences PIK3CG antibody (BD, 611046) was used in western blot on rat samples (fig 1d) and in western blot knockout validation on mouse samples (fig 1d). Mol Cell Biol (2011) ncbi
Articles Reviewed
  1. Chen F, Xiao M, Feng J, Wufur R, Liu K, Hu S, et al. Different Inhibition of Nrf2 by Two Keap1 Isoforms α and β to Shape Malignant Behaviour of Human Hepatocellular Carcinoma. Int J Mol Sci. 2022;23: pubmed publisher
  2. Xia R, Liu T, Li W, Xu X. RNA-binding protein RBM24 represses colorectal tumourigenesis by stabilising PTEN mRNA. Clin Transl Med. 2021;11:e383 pubmed publisher
  3. Huang J, Xiao R, Wang X, Khadka B, Fang Z, Yu M, et al. MicroRNA‑93 knockdown inhibits acute myeloid leukemia cell growth via inactivating the PI3K/AKT pathway by upregulating DAB2. Int J Oncol. 2021;59: pubmed publisher
  4. Sferra R, Pompili S, Cappariello A, Gaudio E, Latella G, Vetuschi A. Prolonged Chronic Consumption of a High Fat with Sucrose Diet Alters the Morphology of the Small Intestine. Int J Mol Sci. 2021;22: pubmed publisher
  5. Zhou H, Li G, Wang Y, Jiang R, Li Y, Wang H, et al. Microbial Metabolite Sodium Butyrate Attenuates Cartilage Degradation by Restoring Impaired Autophagy and Autophagic Flux in Osteoarthritis Development. Front Pharmacol. 2021;12:659597 pubmed publisher
  6. Dong X, Yang Y, Zou Z, Zhao Y, Ci B, Zhong L, et al. Sorting nexin 5 mediates virus-induced autophagy and immunity. Nature. 2021;589:456-461 pubmed publisher
  7. Jiang X, Xu Y, Ren H, Jiang J, Wudu M, Wang Q, et al. KLHL18 inhibits the proliferation, migration, and invasion of non-small cell lung cancer by inhibiting PI3K/PD-L1 axis activity. Cell Biosci. 2020;10:139 pubmed publisher
  8. Li Z, Zhang H, Huang Y, Huang J, Sun P, Zhou N, et al. Autophagy deficiency promotes triple-negative breast cancer resistance to T cell-mediated cytotoxicity by blocking tenascin-C degradation. Nat Commun. 2020;11:3806 pubmed publisher
  9. Boukhalfa A, Nascimbeni A, Ramel D, Dupont N, Hirsch E, Gayral S, et al. PI3KC2α-dependent and VPS34-independent generation of PI3P controls primary cilium-mediated autophagy in response to shear stress. Nat Commun. 2020;11:294 pubmed publisher
  10. Tang K, Tang H, Du Y, Tian T, Xiong S. PAR-2 promotes cell proliferation, migration and invasion through activating PI3K/AKT signaling pathway in oral squamous cell carcinoma. Biosci Rep. 2019;: pubmed publisher
  11. Zhong H, Wu H, Bai H, Wang M, Wen J, Gong J, et al. Panax notoginseng saponins promote liver regeneration through activation of the PI3K/AKT/mTOR cell proliferation pathway and upregulation of the AKT/Bad cell survival pathway in mice. BMC Complement Altern Med. 2019;19:122 pubmed publisher
  12. Birgisdottir A, Mouilleron S, Bhujabal Z, Wirth M, Sjøttem E, Evjen G, et al. Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs. Autophagy. 2019;15:1333-1355 pubmed publisher
  13. Maani N, Sabha N, Rezai K, Ramani A, Groom L, Eltayeb N, et al. Tamoxifen therapy in a murine model of myotubular myopathy. Nat Commun. 2018;9:4849 pubmed publisher
  14. Almeida Souza L, Frank R, García Nafría J, Colussi A, Gunawardana N, Johnson C, et al. A Flat BAR Protein Promotes Actin Polymerization at the Base of Clathrin-Coated Pits. Cell. 2018;174:325-337.e14 pubmed publisher
  15. Hartlova A, Herbst S, Peltier J, Rodgers A, Bilkei Gorzo O, Fearns A, et al. LRRK2 is a negative regulator of Mycobacterium tuberculosis phagosome maturation in macrophages. EMBO J. 2018;37: pubmed publisher
  16. Redka D, Gutschow M, Grinstein S, Canton J. Differential ability of proinflammatory and anti-inflammatory macrophages to perform macropinocytosis. Mol Biol Cell. 2018;29:53-65 pubmed publisher
  17. Wang N, Li J, Zhao T, Li S, Shen C, Li D, et al. FGF-21 Plays a Crucial Role in the Glucose Uptake of Activated Monocytes. Inflammation. 2018;41:73-80 pubmed publisher
  18. Zhao Y, Chen Y, Miao G, Zhao H, Qu W, Li D, et al. The ER-Localized Transmembrane Protein EPG-3/VMP1 Regulates SERCA Activity to Control ER-Isolation Membrane Contacts for Autophagosome Formation. Mol Cell. 2017;67:974-989.e6 pubmed publisher
  19. Simond A, Rao T, Zuo D, Zhao J, Muller W. ErbB2-positive mammary tumors can escape PI3K-p110α loss through downregulation of the Pten tumor suppressor. Oncogene. 2017;36:6059-6066 pubmed publisher
  20. Zhou Y, Huang N, Wu J, Zhen N, Li N, Li Y, et al. Silencing of NRAGE induces autophagy via AMPK/Ulk1/Atg13 signaling pathway in NSCLC cells. Tumour Biol. 2017;39:1010428317709676 pubmed publisher
  21. Ashkenazi A, Bento C, Ricketts T, Vicinanza M, Siddiqi F, Pavel M, et al. Polyglutamine tracts regulate beclin 1-dependent autophagy. Nature. 2017;545:108-111 pubmed publisher
  22. Rong H, Zhao Z, Feng J, Lei Y, Wu H, Sun R, et al. The effects of dexmedetomidine pretreatment on the pro- and anti-inflammation systems after spinal cord injury in rats. Brain Behav Immun. 2017;64:195-207 pubmed publisher
  23. Jung J, Nayak A, Schaeffer V, Starzetz T, Kirsch A, Muller S, et al. Multiplex image-based autophagy RNAi screening identifies SMCR8 as ULK1 kinase activity and gene expression regulator. elife. 2017;6: pubmed publisher
  24. Nascimbeni A, Fanin M, Angelini C, Sandri M. Autophagy dysregulation in Danon disease. Cell Death Dis. 2017;8:e2565 pubmed publisher
  25. Jaber N, Mohd Naim N, Wang Z, Deleon J, Kim S, Zhong H, et al. Vps34 regulates Rab7 and late endocytic trafficking through recruitment of the GTPase-activating protein Armus. J Cell Sci. 2016;129:4424-4435 pubmed
  26. Southworth T, Plumb J, Gupta V, Pearson J, Ramis I, Lehner M, et al. Anti-inflammatory potential of PI3K? and JAK inhibitors in asthma patients. Respir Res. 2016;17:124 pubmed
  27. Kong X, Liu F, Gao J. MiR-155 promotes epithelial-mesenchymal transition in hepatocellular carcinoma cells through the activation of PI3K/SGK3/β-catenin signaling pathways. Oncotarget. 2016;7:66051-66060 pubmed publisher
  28. Lin M, Liu H, Xiong Q, Niu H, Cheng Z, Yamamoto A, et al. Ehrlichia secretes Etf-1 to induce autophagy and capture nutrients for its growth through RAB5 and class III phosphatidylinositol 3-kinase. Autophagy. 2016;12:2145-2166 pubmed
  29. Yuan W, Guo Y, Li X, Deng M, Shen Z, Bo C, et al. MicroRNA-126 inhibits colon cancer cell proliferation and invasion by targeting the chemokine (C-X-C motif) receptor 4 and Ras homolog gene family, member A, signaling pathway. Oncotarget. 2016;7:60230-60244 pubmed publisher
  30. Wang J, Zhou J, Kho D, Reiners J, Wu G. Role for DUSP1 (dual-specificity protein phosphatase 1) in the regulation of autophagy. Autophagy. 2016;12:1791-1803 pubmed
  31. Kaushik A, Shojaie A, Panzitt K, Sonavane R, Venghatakrishnan H, Manikkam M, et al. Inhibition of the hexosamine biosynthetic pathway promotes castration-resistant prostate cancer. Nat Commun. 2016;7:11612 pubmed publisher
  32. Huang Y, Lin C, Liao H, Liu C, Chen Y, Chiu W, et al. Cholesterol overload induces apoptosis in SH-SY5Y human neuroblastoma cells through the up regulation of flotillin-2 in the lipid raft and the activation of BDNF/Trkb signaling. Neuroscience. 2016;328:201-9 pubmed publisher
  33. Park J, Jung C, Seo M, Otto N, Grunwald D, Kim K, et al. The ULK1 complex mediates MTORC1 signaling to the autophagy initiation machinery via binding and phosphorylating ATG14. Autophagy. 2016;12:547-64 pubmed publisher
  34. Lynch J, McEwen R, Crafter C, McDermott U, Garnett M, Barry S, et al. Identification of differential PI3K pathway target dependencies in T-cell acute lymphoblastic leukemia through a large cancer cell panel screen. Oncotarget. 2016;7:22128-39 pubmed publisher
  35. Button R, Vincent J, Strang C, Luo S. Dual PI-3 kinase/mTOR inhibition impairs autophagy flux and induces cell death independent of apoptosis and necroptosis. Oncotarget. 2016;7:5157-75 pubmed publisher
  36. Menter T, Dickenmann M, Juskevicius D, Steiger J, Dirnhofer S, Tzankov A. Comprehensive phenotypic characterization of PTLD reveals potential reliance on EBV or NF-κB signalling instead of B-cell receptor signalling. Hematol Oncol. 2017;35:187-197 pubmed publisher
  37. Ketel K, Krauss M, Nicot A, Puchkov D, Wieffer M, Müller R, et al. A phosphoinositide conversion mechanism for exit from endosomes. Nature. 2016;529:408-12 pubmed publisher
  38. Li W, Zou J, Yue F, Song K, Chen Q, McKeehan W, et al. Defects in MAP1S-mediated autophagy cause reduction in mouse lifespans especially when fibronectin is overexpressed. Aging Cell. 2016;15:370-9 pubmed publisher
  39. Yan L, Liu Y, Xiang J, Wu Q, Xu L, Luo X, et al. PIK3R1 targeting by miR-21 suppresses tumor cell migration and invasion by reducing PI3K/AKT signaling and reversing EMT, and predicts clinical outcome of breast cancer. Int J Oncol. 2016;48:471-84 pubmed publisher
  40. Wang J, Cao Y, Li Q, Yang Y, Jin M, Chen D, et al. A pivotal role of FOS-mediated BECN1/Beclin 1 upregulation in dopamine D2 and D3 receptor agonist-induced autophagy activation. Autophagy. 2015;11:2057-2073 pubmed publisher
  41. Ampofo E, Später T, Müller I, Eichler H, Menger M, Laschke M. The Marine-Derived Kinase Inhibitor Fascaplysin Exerts Anti-Thrombotic Activity. Mar Drugs. 2015;13:6774-91 pubmed publisher
  42. Nemazanyy I, Montagnac G, Russell R, Morzyglod L, Burnol A, Guan K, et al. Class III PI3K regulates organismal glucose homeostasis by providing negative feedback on hepatic insulin signalling. Nat Commun. 2015;6:8283 pubmed publisher
  43. Pavon M, Arroyo Solera I, Tellez Gabriel M, Leon X, Virós D, Lopez M, et al. Enhanced cell migration and apoptosis resistance may underlie the association between high SERPINE1 expression and poor outcome in head and neck carcinoma patients. Oncotarget. 2015;6:29016-33 pubmed publisher
  44. Zarpelon A, Rodrigues F, Lopes A, Souza G, Carvalho T, Pinto L, et al. Spinal cord oligodendrocyte-derived alarmin IL-33 mediates neuropathic pain. FASEB J. 2016;30:54-65 pubmed publisher
  45. Chiang C, Uzoma I, Lane D, Memišević V, Alem F, Yao K, et al. A reverse-phase protein microarray-based screen identifies host signaling dynamics upon Burkholderia spp. infection. Front Microbiol. 2015;6:683 pubmed publisher
  46. Felzen V, Hiebel C, Koziollek Drechsler I, Reißig S, Wolfrum U, Kögel D, et al. Estrogen receptor α regulates non-canonical autophagy that provides stress resistance to neuroblastoma and breast cancer cells and involves BAG3 function. Cell Death Dis. 2015;6:e1812 pubmed publisher
  47. Nishida H, Ikegami A, Kaneko C, Kakuma H, Nishi H, Tanaka N, et al. Dexamethasone and BCAA Failed to Modulate Muscle Mass and mTOR Signaling in GH-Deficient Rats. PLoS ONE. 2015;10:e0128805 pubmed publisher
  48. Sun T, Li X, Zhang P, Chen W, Zhang H, Li D, et al. Acetylation of Beclin 1 inhibits autophagosome maturation and promotes tumour growth. Nat Commun. 2015;6:7215 pubmed publisher
  49. Zou J, Li W, Misra A, Yue F, Song K, Chen Q, et al. The viral restriction factor tetherin prevents leucine-rich pentatricopeptide repeat-containing protein (LRPPRC) from association with beclin 1 and B-cell CLL/lymphoma 2 (Bcl-2) and enhances autophagy and mitophagy. J Biol Chem. 2015;290:7269-79 pubmed publisher
  50. Aki S, Yoshioka K, Okamoto Y, Takuwa N, Takuwa Y. Phosphatidylinositol 3-kinase class II α-isoform PI3K-C2α is required for transforming growth factor β-induced Smad signaling in endothelial cells. J Biol Chem. 2015;290:6086-105 pubmed publisher
  51. Liu H, Xie Q, Xin B, Liu J, Liu Y, Li Y, et al. Inhibition of autophagy recovers cardiac dysfunction and atrophy in response to tail-suspension. Life Sci. 2015;121:1-9 pubmed publisher
  52. Gasser J, Inuzuka H, Lau A, Wei W, Beroukhim R, Toker A. SGK3 mediates INPP4B-dependent PI3K signaling in breast cancer. Mol Cell. 2014;56:595-607 pubmed publisher
  53. Gassen N, Hartmann J, Zschocke J, Stepan J, Häfner K, Zellner A, et al. Association of FKBP51 with priming of autophagy pathways and mediation of antidepressant treatment response: evidence in cells, mice, and humans. PLoS Med. 2014;11:e1001755 pubmed publisher
  54. Wang Y, Kuramitsu Y, Tokuda K, Baron B, Kitagawa T, Akada J, et al. Gemcitabine induces poly (ADP-ribose) polymerase-1 (PARP-1) degradation through autophagy in pancreatic cancer. PLoS ONE. 2014;9:e109076 pubmed publisher
  55. Zhong Y, Morris D, Jin L, Patel M, Karunakaran S, Fu Y, et al. Nrbf2 protein suppresses autophagy by modulating Atg14L protein-containing Beclin 1-Vps34 complex architecture and reducing intracellular phosphatidylinositol-3 phosphate levels. J Biol Chem. 2014;289:26021-37 pubmed publisher
  56. Padiya R, Chowdhury D, Borkar R, Srinivas R, Pal Bhadra M, Banerjee S. Garlic attenuates cardiac oxidative stress via activation of PI3K/AKT/Nrf2-Keap1 pathway in fructose-fed diabetic rat. PLoS ONE. 2014;9:e94228 pubmed publisher
  57. Morabito M, Berman D, Schneider R, Zhang Y, Leibel R, Small S. Hyperleucinemia causes hippocampal retromer deficiency linking diabetes to Alzheimer's disease. Neurobiol Dis. 2014;65:188-92 pubmed publisher
  58. Bauckman K, Haller E, Flores I, Nanjundan M. Iron modulates cell survival in a Ras- and MAPK-dependent manner in ovarian cells. Cell Death Dis. 2013;4:e592 pubmed publisher
  59. van der Vorst E, Vanags L, Dunn L, Prosser H, Rye K, Bursill C. High-density lipoproteins suppress chemokine expression and proliferation in human vascular smooth muscle cells. FASEB J. 2013;27:1413-25 pubmed publisher
  60. Harris D, Vogel P, Wims M, Moberg K, Humphries J, Jhaver K, et al. Requirement for class II phosphoinositide 3-kinase C2alpha in maintenance of glomerular structure and function. Mol Cell Biol. 2011;31:63-80 pubmed publisher