This is a Validated Antibody Database (VAD) review about human PIAS4, based on 9 published articles (read how Labome selects the articles), using PIAS4 antibody in all methods. It is aimed to help Labome visitors find the most suited PIAS4 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
PIAS4 synonym: PIAS-gamma; PIASY; Piasg; ZMIZ6; E3 SUMO-protein ligase PIAS4; RING-type E3 ubiquitin transferase PIAS4; protein inhibitor of activated STAT protein 4; protein inhibitor of activated STAT protein PIASy; protein inhibitor of activated STAT protein gamma; zinc finger, MIZ-type containing 6

Santa Cruz Biotechnology
mouse monoclonal (C-11)
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 3d
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 3c
Santa Cruz Biotechnology PIAS4 antibody (Santa Cruz, sc-166706) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig 3d) and in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig 3c). Sci Rep (2016) ncbi
mouse monoclonal (F-9)
  • western blot; human; fig 3e
Santa Cruz Biotechnology PIAS4 antibody (Santa Cruz Biotechnology, sc-166744) was used in western blot on human samples (fig 3e). Nucleic Acids Res (2015) ncbi
LifeSpan Biosciences
rabbit polyclonal
  • immunocytochemistry; human; fig 1
  • western blot; human
LifeSpan Biosciences PIAS4 antibody (LsBio, LS-C108719) was used in immunocytochemistry on human samples (fig 1) and in western blot on human samples . J Virol (2016) ncbi
rabbit polyclonal
  • immunocytochemistry; human; fig 2
  • western blot; human; fig 3
LifeSpan Biosciences PIAS4 antibody (LsBio, LS-C108719) was used in immunocytochemistry on human samples (fig 2) and in western blot on human samples (fig 3). J Virol (2016) ncbi
Abcam
rabbit polyclonal
  • western blot; mouse; 1:1000; fig 2a
In order to determine how reuglations of m TORC1 signalling occurs by SUMOylation of AMPK alpha 1 through PIAS4, Abcam PIAS4 antibody (Abcam, ab58416) was used in western blot on mouse samples at 1:1000 (fig 2a). Nat Commun (2015) ncbi
Proteintech Group
rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 7c
Proteintech Group PIAS4 antibody (Proteintech, 14242-1-AP) was used in western blot on human samples at 1:1000 (fig 7c). Nat Commun (2016) ncbi
MilliporeSigma
rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig s8a
MilliporeSigma PIAS4 antibody (Sigma-Aldrich, AV33011) was used in western blot on human samples at 1:1000 (fig s8a). Nat Commun (2018) ncbi
Cell Signaling Technology
rabbit monoclonal (D2F12)
  • western blot; human; loading ...; fig 4b
In order to investigate the oncogenic effect of miR-210-3p in prostate cancer and bone metastasis and its mechanism, Cell Signaling Technology PIAS4 antibody (cell signalling, 4392) was used in western blot on human samples (fig 4b). Mol Cancer (2017) ncbi
rabbit monoclonal (D2F12)
  • western blot; rat; 1:1000; loading ...; fig s2a
Cell Signaling Technology PIAS4 antibody (Cell Signaling, 4392) was used in western blot on rat samples at 1:1000 (fig s2a). Cell Death Differ (2017) ncbi
Articles Reviewed
  1. He Z, Zhang J, Huang Z, Du Q, Li N, Zhang Q, et al. Sumoylation of RORγt regulates TH17 differentiation and thymocyte development. Nat Commun. 2018;9:4870 pubmed publisher
  2. Ren D, Yang Q, Dai Y, Guo W, Du H, Song L, et al. Oncogenic miR-210-3p promotes prostate cancer cell EMT and bone metastasis via NF-?B signaling pathway. Mol Cancer. 2017;16:117 pubmed publisher
  3. Tao C, Hsu W, Ma Y, Cheng S, Lee E. Epigenetic regulation of HDAC1 SUMOylation as an endogenous neuroprotection against Aβ toxicity in a mouse model of Alzheimer's disease. Cell Death Differ. 2017;24:597-614 pubmed publisher
  4. Yan C, Yu C, Zhang D, Cui Y, Zhou J, Cui S. Protein Inhibitor of Activated STAT Y (PIASy) Regulates Insulin Secretion by Interacting with LIM Homeodomain Transcription Factor Isl1. Sci Rep. 2016;6:39308 pubmed publisher
  5. Despras E, Sittewelle M, Pouvelle C, Delrieu N, Cordonnier A, Kannouche P. Rad18-dependent SUMOylation of human specialized DNA polymerase eta is required to prevent under-replicated DNA. Nat Commun. 2016;7:13326 pubmed publisher
  6. Brown J, Conn K, Wasson P, Charman M, Tong L, Grant K, et al. SUMO Ligase Protein Inhibitor of Activated STAT1 (PIAS1) Is a Constituent Promyelocytic Leukemia Nuclear Body Protein That Contributes to the Intrinsic Antiviral Immune Response to Herpes Simplex Virus 1. J Virol. 2016;90:5939-5952 pubmed publisher
  7. Conn K, Wasson P, McFarlane S, Tong L, Brown J, Grant K, et al. Novel Role for Protein Inhibitor of Activated STAT 4 (PIAS4) in the Restriction of Herpes Simplex Virus 1 by the Cellular Intrinsic Antiviral Immune Response. J Virol. 2016;90:4807-4826 pubmed publisher
  8. Yan Y, Ollila S, Wong I, Vallenius T, Palvimo J, Vaahtomeri K, et al. SUMOylation of AMPKα1 by PIAS4 specifically regulates mTORC1 signalling. Nat Commun. 2015;6:8979 pubmed publisher
  9. Wu Z, Wang C, Bai M, Li X, Mei Q, Li X, et al. An LRP16-containing preassembly complex contributes to NF-κB activation induced by DNA double-strand breaks. Nucleic Acids Res. 2015;43:3167-79 pubmed publisher