This is a Validated Antibody Database (VAD) review about human PGAM5, based on 4 published articles (read how Labome selects the articles), using PGAM5 antibody in all methods. It is aimed to help Labome visitors find the most suited PGAM5 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
PGAM5 synonym: BXLBV68; serine/threonine-protein phosphatase PGAM5, mitochondrial; Bcl-XL-binding protein v68; PGAM family member 5, serine/threonine protein phosphatase, mitochondrial; phosphoglycerate mutase family member 5

Knockout validation
Abcam
rabbit polyclonal
  • western blot knockout validation; mouse; fig 1
Abcam PGAM5 antibody (Abcam, ab126534) was used in western blot knockout validation on mouse samples (fig 1). J Immunol (2016) ncbi
Abcam
rabbit polyclonal
  • western blot knockout validation; mouse; fig s1f
Abcam PGAM5 antibody (Abcam, Ab126534) was used in western blot knockout validation on mouse samples (fig s1f). Nat Commun (2014) ncbi
Abcam
rabbit polyclonal
  • western blot; mouse; loading ...; fig 7a
Abcam PGAM5 antibody (Abcam, ab126534) was used in western blot on mouse samples (fig 7a). J Cell Biol (2017) ncbi
rabbit polyclonal
  • immunocytochemistry; common platanna; loading ...; fig 6c
  • western blot; common platanna; 1:1000; loading ...; fig s4c
  • western blot; human; 1:1000; loading ...; fig s6b
Abcam PGAM5 antibody (Abcam, ab126534) was used in immunocytochemistry on common platanna samples (fig 6c), in western blot on common platanna samples at 1:1000 (fig s4c) and in western blot on human samples at 1:1000 (fig s6b). Development (2017) ncbi
rabbit polyclonal
  • western blot knockout validation; mouse; fig 1
Abcam PGAM5 antibody (Abcam, ab126534) was used in western blot knockout validation on mouse samples (fig 1). J Immunol (2016) ncbi
rabbit polyclonal
  • western blot knockout validation; mouse; fig s1f
Abcam PGAM5 antibody (Abcam, Ab126534) was used in western blot knockout validation on mouse samples (fig s1f). Nat Commun (2014) ncbi
Articles Reviewed
  1. Hos N, Ganesan R, Gutierrez S, Hos D, Klimek J, Abdullah Z, et al. Type I interferon enhances necroptosis of Salmonella Typhimurium-infected macrophages by impairing antioxidative stress responses. J Cell Biol. 2017;216:4107-4121 pubmed publisher
  2. Rauschenberger V, Bernkopf D, Krenn S, Jalal K, Heller J, Behrens J, et al. The phosphatase Pgam5 antagonizes Wnt/?-Catenin signaling in embryonic anterior-posterior axis patterning. Development. 2017;144:2234-2247 pubmed publisher
  3. Moriwaki K, Farias Luz N, Balaji S, De Rosa M, O Donnell C, Gough P, et al. The Mitochondrial Phosphatase PGAM5 Is Dispensable for Necroptosis but Promotes Inflammasome Activation in Macrophages. J Immunol. 2016;196:407-15 pubmed publisher
  4. Lu W, Karuppagounder S, Springer D, Allen M, Zheng L, Chao B, et al. Genetic deficiency of the mitochondrial protein PGAM5 causes a Parkinson's-like movement disorder. Nat Commun. 2014;5:4930 pubmed publisher