This is a Validated Antibody Database (VAD) review about human PERK, based on 115 published articles (read how Labome selects the articles), using PERK antibody in all methods. It is aimed to help Labome visitors find the most suited PERK antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
PERK synonym: PEK; PERK; WRS

Knockout validation
Cell Signaling Technology
domestic rabbit monoclonal (C33E10)
  • western blot knockout validation; mouse; loading ...; fig 2b
Cell Signaling Technology PERK antibody (Cell Signaling, 3192) was used in western blot knockout validation on mouse samples (fig 2b). PLoS Biol (2021) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D11A8)
  • western blot knockout validation; human; 1:1000; loading ...; fig 1f, s4a
Cell Signaling Technology PERK antibody (CST, 5683) was used in western blot knockout validation on human samples at 1:1000 (fig 1f, s4a). Nat Commun (2020) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D11A8)
  • western blot knockout validation; human; fig 3
Cell Signaling Technology PERK antibody (Cell Signaling, 5683) was used in western blot knockout validation on human samples (fig 3). Cell Death Dis (2018) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (C33E10)
  • western blot knockout validation; mouse; 1:500; fig 6d
In order to examine the impact of the unfolded protein response in satellite cell homeostasis during regenerative myogenesis, Cell Signaling Technology PERK antibody (Cell signaling, 3192) was used in western blot knockout validation on mouse samples at 1:500 (fig 6d). elife (2017) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (C33E10)
  • western blot knockout validation; mouse; loading ...; fig 2b
Cell Signaling Technology PERK antibody (Cell signaling, 3192) was used in western blot knockout validation on mouse samples (fig 2b). Oncotarget (2016) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (C33E10)
  • western blot knockout validation; mouse; fig 5
In order to test if suppressing eIF2alpha kinases alleviates synaptic plasticity and memory deficits in a mouse model of Alzheimer's disease, Cell Signaling Technology PERK antibody (Cell Signaling, 3192) was used in western blot knockout validation on mouse samples (fig 5). Nat Neurosci (2013) ncbi
Santa Cruz Biotechnology
mouse monoclonal (B-5)
  • western blot; human; loading ...; fig 3e
Santa Cruz Biotechnology PERK antibody (Santa Cruz, sc-377400) was used in western blot on human samples (fig 3e). J Exp Clin Cancer Res (2022) ncbi
mouse monoclonal (B-5)
  • immunohistochemistry; human; fig 4e
Santa Cruz Biotechnology PERK antibody (Santa Cruz, sc-377400) was used in immunohistochemistry on human samples (fig 4e). Oncogene (2017) ncbi
mouse monoclonal (B-5)
  • western blot; mouse; loading ...; fig 3a
Santa Cruz Biotechnology PERK antibody (Santa Cruz, sc-377400) was used in western blot on mouse samples (fig 3a). Int J Mol Sci (2016) ncbi
mouse monoclonal (B-5)
  • western blot; mouse; 1:200; fig 3
Santa Cruz Biotechnology PERK antibody (Santa Cruz, sc-377400) was used in western blot on mouse samples at 1:200 (fig 3). Exp Ther Med (2016) ncbi
mouse monoclonal (B-5)
  • western blot; human; loading ...; fig 6b
Santa Cruz Biotechnology PERK antibody (Santa Cruz Biotechnology, sc-377400) was used in western blot on human samples (fig 6b). Oncotarget (2016) ncbi
mouse monoclonal (B-5)
  • western blot; human; 1:200; fig 7A
Santa Cruz Biotechnology PERK antibody (Santa Cruz, sc-377400) was used in western blot on human samples at 1:200 (fig 7A). PLoS ONE (2016) ncbi
mouse monoclonal (B-5)
  • western blot; human; fig 5
Santa Cruz Biotechnology PERK antibody (santa Cruz, sc-377400) was used in western blot on human samples (fig 5). Cell Death Dis (2016) ncbi
mouse monoclonal (B-5)
  • western blot; human; fig 5
Santa Cruz Biotechnology PERK antibody (santa Cruz, sc-377400) was used in western blot on human samples (fig 5). Sci Signal (2016) ncbi
Abcam
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:500; loading ...; fig 5d
Abcam PERK antibody (Abcam, ab192591) was used in immunohistochemistry on mouse samples at 1:500 (fig 5d). elife (2022) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 2f
Abcam PERK antibody (Abcam, ab192591) was used in western blot on human samples (fig 2f). Int J Mol Sci (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:80; loading ...; fig 2b
Abcam PERK antibody (Abcam, ab192591) was used in immunohistochemistry on mouse samples at 1:80 (fig 2b). Cancers (Basel) (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; loading ...; fig 4a
Abcam PERK antibody (Abcam, ab192591) was used in immunohistochemistry on mouse samples (fig 4a). Exp Ther Med (2021) ncbi
domestic rabbit polyclonal
  • western blot; rat; 1:1000; loading ...; fig 5b
Abcam PERK antibody (Abcam, ab79483) was used in western blot on rat samples at 1:1000 (fig 5b). Biosci Rep (2019) ncbi
domestic rabbit polyclonal
  • western blot; mouse; fig 7a
Abcam PERK antibody (Abcam, ab192591) was used in western blot on mouse samples (fig 7a). Int J Biol Sci (2019) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig s4e
Abcam PERK antibody (Abcam, ab217322) was used in immunohistochemistry - frozen section on mouse samples at 1:100 (fig s4e). Cell (2019) ncbi
domestic rabbit polyclonal
Abcam PERK antibody (Abcam, ab192591) was used . EMBO Mol Med (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:500; loading ...; fig 4a
In order to determine the effects of High mobility group box 1 on cytokine secretion from mesenchymal stem cells, Abcam PERK antibody (Abcam, ab65142) was used in western blot on human samples at 1:500 (fig 4a). Exp Ther Med (2016) ncbi
Invitrogen
domestic rabbit polyclonal
  • immunocytochemistry; rat; loading ...; fig 4a
Invitrogen PERK antibody (Thermo Fisher, PA5- 37773) was used in immunocytochemistry on rat samples (fig 4a). Anal Cell Pathol (Amst) (2021) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; loading ...; fig s8e
Cell Signaling Technology PERK antibody (Cell Signaling, 3192) was used in western blot on mouse samples (fig s8e). Leukemia (2022) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; loading ...; fig 9a
Cell Signaling Technology PERK antibody (Cell Signaling, C33E10) was used in western blot on mouse samples (fig 9a). Glia (2022) ncbi
domestic rabbit monoclonal (D11A8)
  • western blot; human; 1:1000; loading ...; fig 3m, e3e, e3f, e3g
Cell Signaling Technology PERK antibody (Cell Signaling, 5683) was used in western blot on human samples at 1:1000 (fig 3m, e3e, e3f, e3g). Nat Cancer (2022) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; 1:1000; loading ...; fig 4k
Cell Signaling Technology PERK antibody (Cell Signaling, 3192) was used in western blot on mouse samples at 1:1000 (fig 4k). Nat Cell Biol (2022) ncbi
domestic rabbit monoclonal (D11A8)
  • western blot; human; loading ...; fig 5i
Cell Signaling Technology PERK antibody (CST, 5683) was used in western blot on human samples (fig 5i). Cell Rep (2022) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; loading ...; fig 2a, 6b
Cell Signaling Technology PERK antibody (Cell Signaling, 3192) was used in western blot on mouse samples (fig 2a, 6b). Theranostics (2022) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; human; fig 7b
  • western blot; mouse; fig s5j
Cell Signaling Technology PERK antibody (Cell Signaling, 3192) was used in western blot on human samples (fig 7b) and in western blot on mouse samples (fig s5j). J Exp Med (2022) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; loading ...; fig 4c
Cell Signaling Technology PERK antibody (Cell signaling, 3192) was used in western blot on mouse samples (fig 4c). iScience (2021) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; loading ...; fig 6f
Cell Signaling Technology PERK antibody (CST, 3192) was used in western blot on mouse samples (fig 6f). Cell Rep (2021) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; 1:1000; loading ...; fig 1b
Cell Signaling Technology PERK antibody (CST, 3192) was used in western blot on mouse samples at 1:1000 (fig 1b). Antioxidants (Basel) (2021) ncbi
domestic rabbit monoclonal (D11A8)
  • western blot; human; loading ...; fig 2f
Cell Signaling Technology PERK antibody (CST, 5683) was used in western blot on human samples (fig 2f). Int J Mol Sci (2021) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; 1:1000; loading ...; fig 5c
  • western blot; human; 1:1000; loading ...; fig 6h
Cell Signaling Technology PERK antibody (CST, 3192S) was used in western blot on mouse samples at 1:1000 (fig 5c) and in western blot on human samples at 1:1000 (fig 6h). J Genet Genomics (2021) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; human; 1:500; loading ...; fig 3d
Cell Signaling Technology PERK antibody (Cell Signaling, 3192) was used in western blot on human samples at 1:500 (fig 3d). Nucleic Acids Res (2021) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; 1:1000; loading ...; fig 5a
Cell Signaling Technology PERK antibody (Cell signaling, 3192) was used in western blot on mouse samples at 1:1000 (fig 5a). iScience (2021) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; loading ...; fig 7c
Cell Signaling Technology PERK antibody (Cell SignalingTechnology, 3192) was used in western blot on mouse samples (fig 7c). Cell Mol Gastroenterol Hepatol (2021) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; fig 1a
Cell Signaling Technology PERK antibody (Cell Signaling Technology, 3192) was used in western blot on mouse samples (fig 1a). Mol Brain (2021) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; loading ...; fig 6d
  • western blot; human; loading ...; fig 5a
Cell Signaling Technology PERK antibody (CST, 3192S) was used in western blot on mouse samples (fig 6d) and in western blot on human samples (fig 5a). J Biol Chem (2021) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; 1:1000; loading ...; fig 2a
Cell Signaling Technology PERK antibody (Cell Signaling Technology, 3,192) was used in western blot on mouse samples at 1:1000 (fig 2a). Front Pharmacol (2021) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot knockout validation; mouse; loading ...; fig 2b
Cell Signaling Technology PERK antibody (Cell Signaling, 3192) was used in western blot knockout validation on mouse samples (fig 2b). PLoS Biol (2021) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; 1:1000; loading ...; fig s8a, s9a, s9b, s9c
Cell Signaling Technology PERK antibody (CST, 3192) was used in western blot on mouse samples at 1:1000 (fig s8a, s9a, s9b, s9c). Nat Commun (2021) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; human; loading ...; fig 6a
Cell Signaling Technology PERK antibody (Cell Signaling, 3192) was used in western blot on human samples (fig 6a). Biomolecules (2021) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; human; loading ...; fig 3d
Cell Signaling Technology PERK antibody (Cell signalling, 3192) was used in western blot on human samples (fig 3d). BMC Biol (2020) ncbi
domestic rabbit monoclonal (D11A8)
  • western blot knockout validation; human; 1:1000; loading ...; fig 1f, s4a
Cell Signaling Technology PERK antibody (CST, 5683) was used in western blot knockout validation on human samples at 1:1000 (fig 1f, s4a). Nat Commun (2020) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; loading ...; fig s2a
Cell Signaling Technology PERK antibody (Cell Signaling, 3192) was used in western blot on mouse samples (fig s2a). Neuron (2020) ncbi
domestic rabbit monoclonal (D11A8)
  • western blot; human; loading ...; fig 1a, 5b
Cell Signaling Technology PERK antibody (Cell Signaling, 5683) was used in western blot on human samples (fig 1a, 5b). PLoS Pathog (2019) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; 1:1000; loading ...; fig s4c
Cell Signaling Technology PERK antibody (Cell Signaling Technology, 3192) was used in western blot on mouse samples at 1:1000 (fig s4c). Science (2019) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; loading ...; fig 5f
Cell Signaling Technology PERK antibody (Cell Signaling, 3192) was used in western blot on mouse samples (fig 5f). Cell (2019) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; loading ...; fig 5a
Cell Signaling Technology PERK antibody (CST, 3192) was used in western blot on mouse samples (fig 5a). Cell (2019) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; 1:10,000; loading ...; fig 5a
Cell Signaling Technology PERK antibody (Cell Signaling Technology, 3192S) was used in western blot on mouse samples at 1:10,000 (fig 5a). J Biol Chem (2019) ncbi
domestic rabbit monoclonal (D11A8)
  • western blot; human; 1:200; loading ...; fig s2a
Cell Signaling Technology PERK antibody (Cell Signaling, 5683S) was used in western blot on human samples at 1:200 (fig s2a). Sci Adv (2019) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; loading ...; fig 2b
Cell Signaling Technology PERK antibody (Cell Signaling, 3192) was used in western blot on mouse samples (fig 2b). Nature (2019) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; 1:1000; loading ...; fig 2c
Cell Signaling Technology PERK antibody (Cell Signaling Technology, 3192) was used in western blot on mouse samples at 1:1000 (fig 2c). Nat Commun (2019) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; 1:1000; loading ...; fig 5f
Cell Signaling Technology PERK antibody (Cell Signaling, 3192) was used in western blot on mouse samples at 1:1000 (fig 5f). Nat Commun (2019) ncbi
domestic rabbit monoclonal (D11A8)
  • western blot; mouse; loading ...; fig 1h
Cell Signaling Technology PERK antibody (Cell Signaling Technology, 5683) was used in western blot on mouse samples (fig 1h). Cancer Cell (2019) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; loading ...; fig 6d
Cell Signaling Technology PERK antibody (Cell Signaling, 3192) was used in western blot on mouse samples (fig 6d). Cell Discov (2019) ncbi
domestic rabbit monoclonal (D11A8)
  • western blot; human; 1:1000; loading ...; fig 3b
Cell Signaling Technology PERK antibody (Cell Signaling, 5683) was used in western blot on human samples at 1:1000 (fig 3b). Nat Commun (2018) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; loading ...; fig 3h
Cell Signaling Technology PERK antibody (Cell Signaling Technology, 3192) was used in western blot on mouse samples (fig 3h). FASEB J (2019) ncbi
domestic rabbit monoclonal (D11A8)
  • western blot knockout validation; human; fig 3
Cell Signaling Technology PERK antibody (Cell Signaling, 5683) was used in western blot knockout validation on human samples (fig 3). Cell Death Dis (2018) ncbi
domestic rabbit monoclonal (D11A8)
  • western blot; human; loading ...; fig s4c
Cell Signaling Technology PERK antibody (Cell Signaling, 5683) was used in western blot on human samples (fig s4c). Oncogene (2018) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; human; fig 3b
Cell Signaling Technology PERK antibody (CST, 3192S) was used in western blot on human samples (fig 3b). Nat Commun (2017) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; fig 2d
Cell Signaling Technology PERK antibody (Cell Signaling, 3192) was used in western blot on mouse samples (fig 2d). J Clin Invest (2018) ncbi
domestic rabbit monoclonal (D11A8)
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 5d
Cell Signaling Technology PERK antibody (Cell Signaling, 5683) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 5d). J Bone Miner Res (2017) ncbi
domestic rabbit monoclonal (D11A8)
  • western blot; human; 1:3000; loading ...; fig 5a
Cell Signaling Technology PERK antibody (Cell Signaling, 5683) was used in western blot on human samples at 1:3000 (fig 5a). Exp Ther Med (2017) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot knockout validation; mouse; 1:500; fig 6d
In order to examine the impact of the unfolded protein response in satellite cell homeostasis during regenerative myogenesis, Cell Signaling Technology PERK antibody (Cell signaling, 3192) was used in western blot knockout validation on mouse samples at 1:500 (fig 6d). elife (2017) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; 1:1000; loading ...; fig 3a
In order to determine the effect of ginsenoside Rg5 on adipose dysfunction and muscle insulin resistance, Cell Signaling Technology PERK antibody (Cell Signaling, 3192) was used in western blot on mouse samples at 1:1000 (fig 3a). Front Pharmacol (2017) ncbi
domestic rabbit monoclonal (D11A8)
  • western blot; human; loading ...; fig 3d
In order to identify compounds that inhibit the proteasome 19S subunit Rpn11, Cell Signaling Technology PERK antibody (Cell Signaling, 5683P) was used in western blot on human samples (fig 3d). Nat Chem Biol (2017) ncbi
domestic rabbit monoclonal (D11A8)
  • western blot; mouse; loading ...; fig s5e
Cell Signaling Technology PERK antibody (Cell Signaling, 5683) was used in western blot on mouse samples (fig s5e). Nature (2017) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; human; 1:1000; loading ...; fig 3a
Cell Signaling Technology PERK antibody (Cell Signaling, 3192S) was used in western blot on human samples at 1:1000 (fig 3a). Nat Commun (2017) ncbi
domestic rabbit monoclonal (D11A8)
  • western blot; human; fig 2a
Cell Signaling Technology PERK antibody (Cell Signaling, 5683) was used in western blot on human samples (fig 2a). Mediators Inflamm (2016) ncbi
domestic rabbit monoclonal (C33E10)
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 2
  • western blot; mouse; 1:500; loading ...; fig 1b
Cell Signaling Technology PERK antibody (Cell Signaling, 3192) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 2) and in western blot on mouse samples at 1:500 (fig 1b). Mol Reprod Dev (2017) ncbi
domestic rabbit monoclonal (C33E10)
  • immunohistochemistry; mouse; 1:100; loading ...; fig 7c
Cell Signaling Technology PERK antibody (CST, 3192) was used in immunohistochemistry on mouse samples at 1:100 (fig 7c). J Am Heart Assoc (2016) ncbi
domestic rabbit monoclonal (D11A8)
  • western blot; human; loading ...; fig s2e
In order to show that 2-hydroxyoleic acid treatment alters cell signaling and intracellular transport, Cell Signaling Technology PERK antibody (Cell Signaling, 5683) was used in western blot on human samples (fig s2e). Oncotarget (2016) ncbi
domestic rabbit monoclonal (D11A8)
  • western blot; rat; loading ...; fig 4a
  • western blot; mouse; loading ...; fig 3b
  • western blot; human; loading ...; fig 8a
Cell Signaling Technology PERK antibody (Cell Signaling, 5683) was used in western blot on rat samples (fig 4a), in western blot on mouse samples (fig 3b) and in western blot on human samples (fig 8a). J Neurosci (2016) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; loading ...; fig 3a
In order to assess cyclic alterations of lipid metabolism over a 24-hour period after binge in small heterodimer partner nuclear receptor knockout mice, Cell Signaling Technology PERK antibody (Cell Signaling, 3192) was used in western blot on mouse samples (fig 3a). Am J Pathol (2016) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; human; 1:1000; fig st1
In order to identify and characterize alterations in signal transduction that occur during the development Lapatinib resistance, Cell Signaling Technology PERK antibody (Cell Signaling, 3192) was used in western blot on human samples at 1:1000 (fig st1). Nat Commun (2016) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; fig 5
Cell Signaling Technology PERK antibody (Cell Signaling, C33E10) was used in western blot on mouse samples (fig 5). Sci Rep (2016) ncbi
domestic rabbit monoclonal (C33E10)
  • other; mouse; 1:500; fig 1
  • western blot; mouse; 1:500; fig 1
In order to assess the role of PERK to working memory, Cell Signaling Technology PERK antibody (cell signaling, 3192) was used in other on mouse samples at 1:500 (fig 1) and in western blot on mouse samples at 1:500 (fig 1). PLoS ONE (2016) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; rat; fig 3a
In order to test if thrombospondin-4 is induced in association with ATF6alpha activation and endoplasmic reticulum expansion, Cell Signaling Technology PERK antibody (Cell Signaling Technology, 3192) was used in western blot on rat samples (fig 3a). Sci Rep (2016) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; 1:1000; fig 2
Cell Signaling Technology PERK antibody (CST, 3192) was used in western blot on mouse samples at 1:1000 (fig 2). Biomed Res Int (2016) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; human; 1:500; loading ...; fig 1a
  • western blot; mouse; 1:500; loading ...; fig 1a
In order to propose that ER stress-induced CHOP activation in the brain links palmitate-induced regulation of leptin and IGF1, Cell Signaling Technology PERK antibody (Cell Signaling, 3192) was used in western blot on human samples at 1:500 (fig 1a) and in western blot on mouse samples at 1:500 (fig 1a). Cell Signal (2016) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; human; 1:500; fig 3
Cell Signaling Technology PERK antibody (Cell Signaling, C33E10) was used in western blot on human samples at 1:500 (fig 3). elife (2016) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; fig 4
In order to analyze exacerbation of palmitate-induced steatosis and toxicity in hepatocytes by low density lipoprotein receptor-related protein-1 deficiency, Cell Signaling Technology PERK antibody (Cell signaling, 3192) was used in western blot on mouse samples (fig 4). J Biol Chem (2016) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; human; fig 1a
Cell Signaling Technology PERK antibody (Cell Signaling Technology, 3192) was used in western blot on human samples (fig 1a). Sci Rep (2016) ncbi
domestic rabbit monoclonal (C33E10)
  • immunohistochemistry; mouse; 1:1000; fig 2
Cell Signaling Technology PERK antibody (Cell Signaling, C33E10) was used in immunohistochemistry on mouse samples at 1:1000 (fig 2). Ann Clin Transl Neurol (2016) ncbi
domestic rabbit monoclonal (D11A8)
  • western blot; mouse; 1:1000; fig 5
Cell Signaling Technology PERK antibody (Cell signaling, 5683) was used in western blot on mouse samples at 1:1000 (fig 5). Diabetologia (2016) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; human; fig 2
Cell Signaling Technology PERK antibody (Cell signalling, C33E10) was used in western blot on human samples (fig 2). Oncogene (2016) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; fig s3
In order to analyze induction of efficient anti-tumor immunity by vaccination with necroptotic cancer cells, Cell Signaling Technology PERK antibody (Cell Signaling, 3192S) was used in western blot on mouse samples (fig s3). Cell Rep (2016) ncbi
domestic rabbit monoclonal (D11A8)
  • western blot; human; 1:1000; fig s5
Cell Signaling Technology PERK antibody (Cell Signaling Technologies, 5683) was used in western blot on human samples at 1:1000 (fig s5). Nat Commun (2016) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; loading ...; fig s5g
Cell Signaling Technology PERK antibody (Cell Signaling, 3192) was used in western blot on mouse samples (fig s5g). Cell (2016) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot knockout validation; mouse; loading ...; fig 2b
Cell Signaling Technology PERK antibody (Cell signaling, 3192) was used in western blot knockout validation on mouse samples (fig 2b). Oncotarget (2016) ncbi
domestic rabbit monoclonal (D11A8)
  • western blot; human; 1:1000; loading ...; fig 2a
Cell Signaling Technology PERK antibody (Cell Signaling, 5683S) was used in western blot on human samples at 1:1000 (fig 2a). Oncotarget (2016) ncbi
domestic rabbit monoclonal (D11A8)
  • western blot; human; fig 4
In order to determine the induction of transforming growth factor beta1 through activation of endoplasmic reticulum stress and the unfolded protein response due to HCV, Cell Signaling Technology PERK antibody (Cell signaling, 5683) was used in western blot on human samples (fig 4). Sci Rep (2016) ncbi
domestic rabbit monoclonal (D11A8)
  • western blot; rat; fig 3
In order to determine regulation of global protein synthesis by inactivating eukaryotic translation initiation factor 2-alpha by the small molecule '1-(4-biphenylylcarbonyl)-4-(5-bromo-2-methoxybenzyl) piperazine oxalate' and its derivatives, Cell Signaling Technology PERK antibody (Cell signaling, 5683) was used in western blot on rat samples (fig 3). Cell Stress Chaperones (2016) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; human; fig 5
In order to study the miR-424(322)-503 cluster in the unfolded protein response, Cell Signaling Technology PERK antibody (Cell signaling, C33E10) was used in western blot on human samples (fig 5). Sci Rep (2015) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; fig 1
Cell Signaling Technology PERK antibody (Cell Signaling, 3192) was used in western blot on mouse samples (fig 1). elife (2015) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; 1:2000; fig 1
Cell Signaling Technology PERK antibody (Cell Signaling, 3192) was used in western blot on mouse samples at 1:2000 (fig 1). Nat Cell Biol (2015) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; human; 1:1000; fig 3
Cell Signaling Technology PERK antibody (Cell signaling, 3192) was used in western blot on human samples at 1:1000 (fig 3). Oncotarget (2015) ncbi
domestic rabbit monoclonal (C33E10)
  • immunocytochemistry; human; 1:500; tbl 4
Cell Signaling Technology PERK antibody (Cell Signaling, 3192) was used in immunocytochemistry on human samples at 1:500 (tbl 4). Sci Rep (2015) ncbi
domestic rabbit monoclonal (D11A8)
  • western blot; human; 1:1000; fig 7
In order to study the role of transmembrane protein 33 in the unfolded protein response, Cell Signaling Technology PERK antibody (Cell Signaling Technology, 5683) was used in western blot on human samples at 1:1000 (fig 7). Breast Cancer Res Treat (2015) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; human; fig 6
Cell Signaling Technology PERK antibody (Cell Signaling, 3192) was used in western blot on human samples (fig 6). Autophagy (2015) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; human
Cell Signaling Technology PERK antibody (Cell Signaling Technology, 3192) was used in western blot on human samples . PLoS ONE (2015) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; fig 4,8
  • western blot; human; fig 4,8
Cell Signaling Technology PERK antibody (cell signaling, 3192) was used in western blot on mouse samples (fig 4,8) and in western blot on human samples (fig 4,8). Mol Cell Biol (2015) ncbi
domestic rabbit monoclonal (C33E10)
  • immunoprecipitation; human; fig 4
In order to elucidate the mechanism by which Ire1alpha cleaves mRNAs at the ER membrane, Cell Signaling Technology PERK antibody (Cell Signalling, 3192) was used in immunoprecipitation on human samples (fig 4). elife (2015) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; human; fig 2
In order to demonstrate that androgen receptor signaling modulates the unfolded protein response in prostate cancer cells, Cell Signaling Technology PERK antibody (Cell Signaling, 3192S) was used in western blot on human samples (fig 2). EMBO Mol Med (2015) ncbi
domestic rabbit monoclonal (D11A8)
  • western blot; rat; 1:500; fig 1
Cell Signaling Technology PERK antibody (Cell Signaling, 5683) was used in western blot on rat samples at 1:500 (fig 1). PLoS ONE (2015) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; 1:1000; fig 6a
Cell Signaling Technology PERK antibody (Cell Signaling Technology, 3192) was used in western blot on mouse samples at 1:1000 (fig 6a). PLoS ONE (2015) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; human
Cell Signaling Technology PERK antibody (CST, 3192) was used in western blot on human samples . Biochem Biophys Res Commun (2015) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; human; 1:1000
Cell Signaling Technology PERK antibody (Cell Signaling, 3192) was used in western blot on human samples at 1:1000. FEBS Lett (2014) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse
In order to study PERK signaling using an analog-sensitive PERK allele that accepts N(6)-alkylated ATP analogs, Cell Signaling Technology PERK antibody (Cell Signaling, 3192) was used in western blot on mouse samples . Cancer Biol Ther (2014) ncbi
domestic rabbit monoclonal (D11A8)
  • western blot; human; 1:1000
Cell Signaling Technology PERK antibody (Cell Signaling Technology, 5683) was used in western blot on human samples at 1:1000. Head Neck (2015) ncbi
domestic rabbit monoclonal (D11A8)
  • western blot; mouse; 1:1000
In order to discuss the role of the unfolded protein response in obesity pathogenesis, Cell Signaling Technology PERK antibody (Cell Signaling Technology, 5683) was used in western blot on mouse samples at 1:1000. Methods Enzymol (2014) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; human
Cell Signaling Technology PERK antibody (Cell Signaling Technology, 3192) was used in western blot on human samples . Int J Oncol (2014) ncbi
domestic rabbit monoclonal (D11A8)
  • western blot; human; 1:500
Cell Signaling Technology PERK antibody (Cell Signaling, 5683) was used in western blot on human samples at 1:500. Autophagy (2013) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot knockout validation; mouse; fig 5
In order to test if suppressing eIF2alpha kinases alleviates synaptic plasticity and memory deficits in a mouse model of Alzheimer's disease, Cell Signaling Technology PERK antibody (Cell Signaling, 3192) was used in western blot knockout validation on mouse samples (fig 5). Nat Neurosci (2013) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse
In order to study the pathogenesis of cardiomyopathy in Friedreich ataxia, Cell Signaling Technology PERK antibody (Cell Signaling Technology, 3192) was used in western blot on mouse samples . Am J Pathol (2013) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; 1:1000
Cell Signaling Technology PERK antibody (Cell Signaling, 3192) was used in western blot on mouse samples at 1:1000. Transl Psychiatry (2013) ncbi
MilliporeSigma
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 2a
MilliporeSigma PERK antibody (Sigma, P0074) was used in western blot on mouse samples (fig 2a). Cell (2019) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; fig 9e
MilliporeSigma PERK antibody (Sigma-Aldrich, P0074) was used in western blot on mouse samples at 1:1000 (fig 9e). Nat Commun (2017) ncbi
Articles Reviewed
  1. Lee A, Pingali S, Pinilla Ibarz J, Atchison M, Koumenis C, Argon Y, et al. Loss of AID exacerbates the malignant progression of CLL. Leukemia. 2022;36:2430-2442 pubmed publisher
  2. Yoshioka N, Kurose M, Yano M, Tran D, Okuda S, Mori Ochiai Y, et al. Isoform-specific mutation in Dystonin-b gene causes late-onset protein aggregate myopathy and cardiomyopathy. elife. 2022;11: pubmed publisher
  3. Bradford B, McGuire L, Hume D, Pridans C, Mabbott N. Microglia deficiency accelerates prion disease but does not enhance prion accumulation in the brain. Glia. 2022;70:2169-2187 pubmed publisher
  4. Liu X, Viswanadhapalli S, Kumar S, Lee T, Moore A, Ma S, et al. Targeting LIPA independent of its lipase activity is a therapeutic strategy in solid tumors via induction of endoplasmic reticulum stress. Nat Cancer. 2022;: pubmed publisher
  5. Verginadis I, Avgousti H, Monslow J, Skoufos G, Chinga F, Kim K, et al. A stromal Integrated Stress Response activates perivascular cancer-associated fibroblasts to drive angiogenesis and tumour progression. Nat Cell Biol. 2022;24:940-953 pubmed publisher
  6. Pillai S, Mahmud I, Mahar R, Griffith C, Langsen M, Nguyen J, et al. Lipogenesis mediated by OGR1 regulates metabolic adaptation to acid stress in cancer cells via autophagy. Cell Rep. 2022;39:110796 pubmed publisher
  7. Liu C, Chen Q, Shang Y, Chen L, Myers J, Awadallah A, et al. Endothelial PERK-ATF4-JAG1 axis activated by T-ALL remodels bone marrow vascular niche. Theranostics. 2022;12:2894-2907 pubmed publisher
  8. Liu M, Wu C, Luo S, Hua Q, Chen H, Weng Y, et al. PERK reprograms hematopoietic progenitor cells to direct tumor-promoting myelopoiesis in the spleen. J Exp Med. 2022;219: pubmed publisher
  9. Salaroglio I, Belisario D, Bironzo P, Ananthanarayanan P, Ricci L, Digiovanni S, et al. SKP2 drives the sensitivity to neddylation inhibitors and cisplatin in malignant pleural mesothelioma. J Exp Clin Cancer Res. 2022;41:75 pubmed publisher
  10. Sugiyama T, Murao N, Kadowaki H, Takao K, Miyakawa T, Matsushita Y, et al. ERAD components Derlin-1 and Derlin-2 are essential for postnatal brain development and motor function. iScience. 2021;24:102758 pubmed publisher
  11. Wani A, Zhu J, ULRICH J, Eteleeb A, Sauerbeck A, Reitz S, et al. Neuronal VCP loss of function recapitulates FTLD-TDP pathology. Cell Rep. 2021;36:109399 pubmed publisher
  12. Cho J, Lee J, Kim H, Lee H, Fang Z, Kwon H, et al. Ethyl Acetate Fraction of Amomum villosum var. xanthioides Attenuates Hepatic Endoplasmic Reticulum Stress-Induced Non-Alcoholic Steatohepatitis via Improvement of Antioxidant Capacities. Antioxidants (Basel). 2021;10: pubmed publisher
  13. Ko P, Choi J, Song S, Keum S, Jeong J, Hwang Y, et al. Microtubule Acetylation Controls MDA-MB-231 Breast Cancer Cell Invasion through the Modulation of Endoplasmic Reticulum Stress. Int J Mol Sci. 2021;22: pubmed publisher
  14. Zhou Y, Ye X, Zhang C, Wang J, Guan Z, Yan J, et al. Ufl1 deficiency causes kidney atrophy associated with disruption of endoplasmic reticulum homeostasis. J Genet Genomics. 2021;48:403-410 pubmed publisher
  15. Torres A, Rodríguez Escribà M, Marcet Houben M, Santos Vieira H, Camacho N, Catena H, et al. Human tRNAs with inosine 34 are essential to efficiently translate eukarya-specific low-complexity proteins. Nucleic Acids Res. 2021;49:7011-7034 pubmed publisher
  16. Li Y, Chen L, Li L, Sottas C, Petrillo S, Lazaris A, et al. Cholesterol-binding translocator protein TSPO regulates steatosis and bile acid synthesis in nonalcoholic fatty liver disease. iScience. 2021;24:102457 pubmed publisher
  17. Cao X, Shu Y, Chen Y, Xu Q, Guo G, Wu Z, et al. Mettl14-Mediated m6A Modification Facilitates Liver Regeneration by Maintaining Endoplasmic Reticulum Homeostasis. Cell Mol Gastroenterol Hepatol. 2021;12:633-651 pubmed publisher
  18. Lim Y, Kim S, Kim E. Palmitate reduces starvation-induced ER stress by inhibiting ER-phagy in hypothalamic cells. Mol Brain. 2021;14:65 pubmed publisher
  19. Chen Y, Hu W, Li Q, Zhao S, Zhao D, Zhang S, et al. NGBR is required to ameliorate type 2 diabetes in mice by enhancing insulin sensitivity. J Biol Chem. 2021;296:100624 pubmed publisher
  20. Kakehashi A, Chariyakornkul A, Suzuki S, Khuanphram N, Tatsumi K, Yamano S, et al. Cache Domain Containing 1 Is a Novel Marker of Non-Alcoholic Steatohepatitis-Associated Hepatocarcinogenesis. Cancers (Basel). 2021;13: pubmed publisher
  21. Yin S, Li L, Tao Y, Yu J, Wei S, Liu M, et al. The Inhibitory Effect of Artesunate on Excessive Endoplasmic Reticulum Stress Alleviates Experimental Colitis in Mice. Front Pharmacol. 2021;12:629798 pubmed publisher
  22. Lu Y, Kavianpour S, Zhang T, Zhang X, Nguyen D, Thombre R, et al. MARK2 phosphorylates eIF2α in response to proteotoxic stress. PLoS Biol. 2021;19:e3001096 pubmed publisher
  23. Yi S, Shi W, Zuo M, Wang S, Ma R, Bi H, et al. Endoplasmic Reticulum Stress Is Involved in Glucocorticoid-Induced Apoptosis in PC12 Cells. Anal Cell Pathol (Amst). 2021;2021:5565671 pubmed publisher
  24. Persaud A, Nair S, Rahman M, Raj R, Weadick B, Nayak D, et al. Facilitative lysosomal transport of bile acids alleviates ER stress in mouse hematopoietic precursors. Nat Commun. 2021;12:1248 pubmed publisher
  25. Obert D, Wolpert A, Grimm N, Korff S. ER stress preconditioning ameliorates liver damage after hemorrhagic shock and reperfusion. Exp Ther Med. 2021;21:248 pubmed publisher
  26. Wanschel A, Guizoni D, Lorza Gil E, Salerno A, Paiva A, Dorighello G, et al. The Presence of Cholesteryl Ester Transfer Protein (CETP) in Endothelial Cells Generates Vascular Oxidative Stress and Endothelial Dysfunction. Biomolecules. 2021;11: pubmed publisher
  27. Clementi E, Inglin L, Beebe E, Gsell C, Garajova Z, Markkanen E. Persistent DNA damage triggers activation of the integrated stress response to promote cell survival under nutrient restriction. BMC Biol. 2020;18:36 pubmed publisher
  28. Mahameed M, Boukeileh S, Obiedat A, Darawshi O, Dipta P, Rimon A, et al. Pharmacological induction of selective endoplasmic reticulum retention as a strategy for cancer therapy. Nat Commun. 2020;11:1304 pubmed publisher
  29. Smith H, Freeman O, Butcher A, Holmqvist S, Humoud I, Schätzl T, et al. Astrocyte Unfolded Protein Response Induces a Specific Reactivity State that Causes Non-Cell-Autonomous Neuronal Degeneration. Neuron. 2020;: pubmed publisher
  30. Johnston B, Pringle E, McCormick C. KSHV activates unfolded protein response sensors but suppresses downstream transcriptional responses to support lytic replication. PLoS Pathog. 2019;15:e1008185 pubmed publisher
  31. Zhu P, Khatiwada S, Cui Y, Reineke L, Dooling S, Kim J, et al. Activation of the ISR mediates the behavioral and neurophysiological abnormalities in Down syndrome. Science. 2019;366:843-849 pubmed publisher
  32. Wang Y, Chiang I, Ohara T, Fujii S, Cheng J, Muegge B, et al. Long-Term Culture Captures Injury-Repair Cycles of Colonic Stem Cells. Cell. 2019;179:1144-1159.e15 pubmed publisher
  33. Li J, Liu Z, Wang L, Xu H, Wang Y. Thousand and one kinase 1 protects MCAO-induced cerebral ischemic stroke in rats by decreasing apoptosis and pro-inflammatory factors. Biosci Rep. 2019;39: pubmed publisher
  34. Hernández Alvarez M, Sebastian D, Vives S, Ivanova S, Bartoccioni P, Kakimoto P, et al. Deficient Endoplasmic Reticulum-Mitochondrial Phosphatidylserine Transfer Causes Liver Disease. Cell. 2019;177:881-895.e17 pubmed publisher
  35. Mogilenko D, Haas J, L homme L, Fleury S, Quemener S, Levavasseur M, et al. Metabolic and Innate Immune Cues Merge into a Specific Inflammatory Response via the UPR. Cell. 2019;177:1201-1216.e19 pubmed publisher
  36. Brody M, Vanhoutte D, Bakshi C, Liu R, Correll R, Sargent M, et al. Disruption of valosin-containing protein activity causes cardiomyopathy and reveals pleiotropic functions in cardiac homeostasis. J Biol Chem. 2019;294:8918-8929 pubmed publisher
  37. Simic M, Moehle E, Schinzel R, Lorbeer F, Halloran J, Heydari K, et al. Transient activation of the UPRER is an essential step in the acquisition of pluripotency during reprogramming. Sci Adv. 2019;5:eaaw0025 pubmed publisher
  38. Schiattarella G, Altamirano F, Tong D, French K, Villalobos E, Kim S, et al. Nitrosative stress drives heart failure with preserved ejection fraction. Nature. 2019;568:351-356 pubmed publisher
  39. Cao Y, Trillo Tinoco J, Sierra R, Anadon C, Dai W, Mohamed E, et al. ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression. Nat Commun. 2019;10:1280 pubmed publisher
  40. Zhu H, Bhatt B, Sivaprakasam S, Cai Y, Liu S, Kodeboyina S, et al. Ufbp1 promotes plasma cell development and ER expansion by modulating distinct branches of UPR. Nat Commun. 2019;10:1084 pubmed publisher
  41. Carugo A, Minelli R, Sapio L, Soeung M, Carbone F, Robinson F, et al. p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors. Cancer Cell. 2019;35:204-220.e9 pubmed publisher
  42. Liu J, Zhu G, Jia N, Wang W, Wang Y, Yin M, et al. CD9 regulates keratinocyte migration by negatively modulating the sheddase activity of ADAM17. Int J Biol Sci. 2019;15:493-506 pubmed publisher
  43. Cai Y, Zhu G, Liu S, Pan Z, Quintero M, Poole C, et al. Indispensable role of the Ubiquitin-fold modifier 1-specific E3 ligase in maintaining intestinal homeostasis and controlling gut inflammation. Cell Discov. 2019;5:7 pubmed publisher
  44. Wheeler M, Jaronen M, Covacu R, Zandee S, Scalisi G, Rothhammer V, et al. Environmental Control of Astrocyte Pathogenic Activities in CNS Inflammation. Cell. 2019;176:581-596.e18 pubmed publisher
  45. Westergard T, McAvoy K, Russell K, Wen X, Pang Y, Morris B, et al. Repeat-associated non-AUG translation in C9orf72-ALS/FTD is driven by neuronal excitation and stress. EMBO Mol Med. 2019;11: pubmed publisher
  46. Jeon Y, Kim T, Park D, Nuovo G, Rhee S, Joshi P, et al. miRNA-mediated TUSC3 deficiency enhances UPR and ERAD to promote metastatic potential of NSCLC. Nat Commun. 2018;9:5110 pubmed publisher
  47. Gallot Y, Bohnert K, Straughn A, Xiong G, Hindi S, Kumar A. PERK regulates skeletal muscle mass and contractile function in adult mice. FASEB J. 2019;33:1946-1962 pubmed publisher
  48. Makhov P, Naito S, Haifler M, Kutikov A, Boumber Y, Uzzo R, et al. The convergent roles of NF-κB and ER stress in sunitinib-mediated expression of pro-tumorigenic cytokines and refractory phenotype in renal cell carcinoma. Cell Death Dis. 2018;9:374 pubmed publisher
  49. Liang H, Xiao J, Zhou Z, Wu J, Ge F, Li Z, et al. Hypoxia induces miR-153 through the IRE1α-XBP1 pathway to fine tune the HIF1α/VEGFA axis in breast cancer angiogenesis. Oncogene. 2018;37:1961-1975 pubmed publisher
  50. Green K, Glineburg M, Kearse M, Flores B, Linsalata A, Fedak S, et al. RAN translation at C9orf72-associated repeat expansions is selectively enhanced by the integrated stress response. Nat Commun. 2017;8:2005 pubmed publisher
  51. Ersoy B, Maner Smith K, Li Y, Alpertunga I, Cohen D. Thioesterase-mediated control of cellular calcium homeostasis enables hepatic ER stress. J Clin Invest. 2018;128:141-156 pubmed publisher
  52. Lüningschrör P, Binotti B, Dombert B, Heimann P, Pérez Lara A, Slotta C, et al. Plekhg5-regulated autophagy of synaptic vesicles reveals a pathogenic mechanism in motoneuron disease. Nat Commun. 2017;8:678 pubmed publisher
  53. Feigenson M, Shull L, Taylor E, Camilleri E, Riester S, Van Wijnen A, et al. Histone Deacetylase 3 Deletion in Mesenchymal Progenitor Cells Hinders Long Bone Development. J Bone Miner Res. 2017;32:2453-2465 pubmed publisher
  54. Xu X, Cui Y, Cao L, Zhang Y, Yin Y, Hu X. PCSK9 regulates apoptosis in human lung adenocarcinoma A549 cells via endoplasmic reticulum stress and mitochondrial signaling pathways. Exp Ther Med. 2017;13:1993-1999 pubmed publisher
  55. Xiong G, Hindi S, Mann A, Gallot Y, Bohnert K, Cavener D, et al. The PERK arm of the unfolded protein response regulates satellite cell-mediated skeletal muscle regeneration. elife. 2017;6: pubmed publisher
  56. Xiao N, Yang L, Yang Y, Liu L, Li J, Liu B, et al. Ginsenoside Rg5 Inhibits Succinate-Associated Lipolysis in Adipose Tissue and Prevents Muscle Insulin Resistance. Front Pharmacol. 2017;8:43 pubmed publisher
  57. Li J, Yakushi T, Parlati F, MacKinnon A, Pérez C, Ma Y, et al. Capzimin is a potent and specific inhibitor of proteasome isopeptidase Rpn11. Nat Chem Biol. 2017;13:486-493 pubmed publisher
  58. Genovese G, Carugo A, TEPPER J, Robinson F, Li L, Svelto M, et al. Synthetic vulnerabilities of mesenchymal subpopulations in pancreatic cancer. Nature. 2017;542:362-366 pubmed publisher
  59. Liu J, Wang Y, Song L, Zeng L, Yi W, Liu T, et al. A critical role of DDRGK1 in endoplasmic reticulum homoeostasis via regulation of IRE1α stability. Nat Commun. 2017;8:14186 pubmed publisher
  60. Feng L, Xue D, Chen E, Zhang W, Gao X, Yu J, et al. HMGB1 promotes the secretion of multiple cytokines and potentiates the osteogenic differentiation of mesenchymal stem cells through the Ras/MAPK signaling pathway. Exp Ther Med. 2016;12:3941-3947 pubmed publisher
  61. Geraghty P, Baumlin N, SALATHE M, Foronjy R, D Armiento J. Glutathione Peroxidase-1 Suppresses the Unfolded Protein Response upon Cigarette Smoke Exposure. Mediators Inflamm. 2016;2016:9461289 pubmed publisher
  62. Yoon J, Park K, Hwang D, Rhee K. Importance of eIF2α phosphorylation as a protective mechanism against heat stress in mouse male germ cells. Mol Reprod Dev. 2017;84:265-274 pubmed publisher
  63. Chao M, Guo J, Cheng W, Zhu X, She Z, Huang Z, et al. Loss of Caspase-Activated DNase Protects Against Atherosclerosis in Apolipoprotein E-Deficient Mice. J Am Heart Assoc. 2016;5: pubmed publisher
  64. Torgersen M, Klokk T, Kavaliauskiene S, Klose C, Simons K, Skotland T, et al. The anti-tumor drug 2-hydroxyoleic acid (Minerval) stimulates signaling and retrograde transport. Oncotarget. 2016;7:86871-86888 pubmed publisher
  65. Sareddy G, Viswanadhapalli S, Surapaneni P, Suzuki T, Brenner A, Vadlamudi R. Novel KDM1A inhibitors induce differentiation and apoptosis of glioma stem cells via unfolded protein response pathway. Oncogene. 2017;36:2423-2434 pubmed publisher
  66. Li S, Yang B, Teguh D, Zhou L, Xu J, Rong L. Amyloid ? Peptide Enhances RANKL-Induced Osteoclast Activation through NF-?B, ERK, and Calcium Oscillation Signaling. Int J Mol Sci. 2016;17: pubmed
  67. Beauvais G, Bode N, Watson J, Wen H, Glenn K, Kawano H, et al. Disruption of Protein Processing in the Endoplasmic Reticulum of DYT1 Knock-in Mice Implicates Novel Pathways in Dystonia Pathogenesis. J Neurosci. 2016;36:10245-10256 pubmed
  68. Yang Z, Tsuchiya H, Zhang Y, Lee S, Liu C, Huang Y, et al. REV-ERB? Activates C/EBP Homologous Protein to Control Small Heterodimer Partner-Mediated Oscillation of Alcoholic Fatty Liver. Am J Pathol. 2016;186:2909-2920 pubmed publisher
  69. Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed publisher
  70. Taniuchi S, Miyake M, Tsugawa K, Oyadomari M, Oyadomari S. Integrated stress response of vertebrates is regulated by four eIF2? kinases. Sci Rep. 2016;6:32886 pubmed publisher
  71. Zhu S, Henninger K, McGrath B, Cavener D. PERK Regulates Working Memory and Protein Synthesis-Dependent Memory Flexibility. PLoS ONE. 2016;11:e0162766 pubmed publisher
  72. Krawczyk K, Ekman M, Rippe C, Grossi M, Nilsson B, Albinsson S, et al. Assessing the contribution of thrombospondin-4 induction and ATF6? activation to endoplasmic reticulum expansion and phenotypic modulation in bladder outlet obstruction. Sci Rep. 2016;6:32449 pubmed publisher
  73. Liu J, Ma Y, Sun C, Li S, Wang J. High Mobility Group Box1 Protein Is Involved in Endoplasmic Reticulum Stress Induced by Clostridium difficile Toxin A. Biomed Res Int. 2016;2016:4130834 pubmed publisher
  74. Marwarha G, Claycombe K, Schommer J, Collins D, Ghribi O. Palmitate-induced Endoplasmic Reticulum stress and subsequent C/EBP? Homologous Protein activation attenuates leptin and Insulin-like growth factor 1 expression in the brain. Cell Signal. 2016;28:1789-805 pubmed publisher
  75. Wang J, Li H, Li B, Gong Q, Chen X, Wang Q. Co-culture of bone marrow stem cells and macrophages indicates intermediate mechanism between local inflammation and innate immune system in diabetic periodontitis. Exp Ther Med. 2016;12:567-572 pubmed
  76. Gallagher C, Garri C, Cain E, Ang K, Wilson C, Chen S, et al. Ceapins are a new class of unfolded protein response inhibitors, selectively targeting the ATF6α branch. elife. 2016;5: pubmed publisher
  77. Madureira P, Bharadwaj A, Bydoun M, Garant K, O Connell P, Lee P, et al. Cell surface protease activation during RAS transformation: Critical role of the plasminogen receptor, S100A10. Oncotarget. 2016;7:47720-47737 pubmed publisher
  78. Hamlin A, Basford J, Jaeschke A, Hui D. LRP1 Protein Deficiency Exacerbates Palmitate-induced Steatosis and Toxicity in Hepatocytes. J Biol Chem. 2016;291:16610-9 pubmed publisher
  79. Zhou X, Wei Y, Qiu S, Xu Y, Zhang T, Zhang S. Propofol Decreases Endoplasmic Reticulum Stress-Mediated Apoptosis in Retinal Pigment Epithelial Cells. PLoS ONE. 2016;11:e0157590 pubmed publisher
  80. Chaveroux C, Sarcinelli C, Barbet V, Belfeki S, Barthelaix A, Ferraro Peyret C, et al. Nutrient shortage triggers the hexosamine biosynthetic pathway via the GCN2-ATF4 signalling pathway. Sci Rep. 2016;6:27278 pubmed publisher
  81. Genç B, Jara J, Schultz M, Manuel M, Stanford M, Gautam M, et al. Absence of UCHL 1 function leads to selective motor neuropathy. Ann Clin Transl Neurol. 2016;3:331-45 pubmed publisher
  82. Plucińska K, Dekeryte R, Koss D, Shearer K, Mody N, Whitfield P, et al. Neuronal human BACE1 knockin induces systemic diabetes in mice. Diabetologia. 2016;59:1513-1523 pubmed publisher
  83. Gupta A, Hossain M, Miller N, Kerin M, Callagy G, Gupta S. NCOA3 coactivator is a transcriptional target of XBP1 and regulates PERK-eIF2α-ATF4 signalling in breast cancer. Oncogene. 2016;35:5860-5871 pubmed publisher
  84. Aaes T, Kaczmarek A, Delvaeye T, De Craene B, De Koker S, Heyndrickx L, et al. Vaccination with Necroptotic Cancer Cells Induces Efficient Anti-tumor Immunity. Cell Rep. 2016;15:274-87 pubmed publisher
  85. Gandin V, Masvidal L, Cargnello M, Gyenis L, McLaughlan S, Cai Y, et al. mTORC1 and CK2 coordinate ternary and eIF4F complex assembly. Nat Commun. 2016;7:11127 pubmed publisher
  86. Llambi F, Wang Y, Victor B, Yang M, Schneider D, Gingras S, et al. BOK Is a Non-canonical BCL-2 Family Effector of Apoptosis Regulated by ER-Associated Degradation. Cell. 2016;165:421-33 pubmed publisher
  87. Saveljeva S, Cleary P, Mnich K, Ayo A, Pakos Zebrucka K, Patterson J, et al. Endoplasmic reticulum stress-mediated induction of SESTRIN 2 potentiates cell survival. Oncotarget. 2016;7:12254-66 pubmed publisher
  88. Tibullo D, Barbagallo I, Giallongo C, Vanella L, Conticello C, Romano A, et al. Heme oxygenase-1 nuclear translocation regulates bortezomibinduced cytotoxicity and mediates genomic instability in myeloma cells. Oncotarget. 2016;7:28868-80 pubmed publisher
  89. Chusri P, Kumthip K, Hong J, Zhu C, Duan X, Jilg N, et al. HCV induces transforming growth factor β1 through activation of endoplasmic reticulum stress and the unfolded protein response. Sci Rep. 2016;6:22487 pubmed publisher
  90. Colangelo T, Polcaro G, Ziccardi P, Muccillo L, Galgani M, Pucci B, et al. The miR-27a-calreticulin axis affects drug-induced immunogenic cell death in human colorectal cancer cells. Cell Death Dis. 2016;7:e2108 pubmed publisher
  91. Kline C, van den Heuvel A, Allen J, Prabhu V, Dicker D, El Deiry W. ONC201 kills solid tumor cells by triggering an integrated stress response dependent on ATF4 activation by specific eIF2α kinases. Sci Signal. 2016;9:ra18 pubmed publisher
  92. Hong M, Nam K, Kim K, Kim S, Kim I. The small molecule '1-(4-biphenylylcarbonyl)-4-(5-bromo-2-methoxybenzyl) piperazine oxalate' and its derivatives regulate global protein synthesis by inactivating eukaryotic translation initiation factor 2-alpha. Cell Stress Chaperones. 2016;21:485-97 pubmed publisher
  93. Gupta A, Hossain M, Read D, Hetz C, Samali A, Gupta S. PERK regulated miR-424(322)-503 cluster fine-tunes activation of IRE1 and ATF6 during Unfolded Protein Response. Sci Rep. 2015;5:18304 pubmed publisher
  94. Gao X, Krokowski D, Guan B, Bederman I, Majumder M, Parisien M, et al. Quantitative H2S-mediated protein sulfhydration reveals metabolic reprogramming during the integrated stress response. elife. 2015;4:e10067 pubmed publisher
  95. Sun S, Shi G, Sha H, Ji Y, Han X, Shu X, et al. IRE1α is an endogenous substrate of endoplasmic-reticulum-associated degradation. Nat Cell Biol. 2015;17:1546-55 pubmed publisher
  96. Patel M, Jacobson B, Ji Y, Drees J, Tang S, Xiong K, et al. Vesicular stomatitis virus expressing interferon-β is oncolytic and promotes antitumor immune responses in a syngeneic murine model of non-small cell lung cancer. Oncotarget. 2015;6:33165-77 pubmed publisher
  97. Nath A, Li I, Roberts L, Chan C. Elevated free fatty acid uptake via CD36 promotes epithelial-mesenchymal transition in hepatocellular carcinoma. Sci Rep. 2015;5:14752 pubmed publisher
  98. Sakabe I, Hu R, Jin L, Clarke R, Kasid U. TMEM33: a new stress-inducible endoplasmic reticulum transmembrane protein and modulator of the unfolded protein response signaling. Breast Cancer Res Treat. 2015;153:285-97 pubmed publisher
  99. Artero Castro A, Perez Alea M, Feliciano A, Leal J, Genestar M, Castellvi J, et al. Disruption of the ribosomal P complex leads to stress-induced autophagy. Autophagy. 2015;11:1499-519 pubmed publisher
  100. D Osualdo A, Anania V, Yu K, Lill J, Kaufman R, Matsuzawa S, et al. Transcription Factor ATF4 Induces NLRP1 Inflammasome Expression during Endoplasmic Reticulum Stress. PLoS ONE. 2015;10:e0130635 pubmed publisher
  101. So J, Cho S, Min S, Kimball S, Lee A. IRE1α-Dependent Decay of CReP/Ppp1r15b mRNA Increases Eukaryotic Initiation Factor 2α Phosphorylation and Suppresses Protein Synthesis. Mol Cell Biol. 2015;35:2761-70 pubmed publisher
  102. Plumb R, Zhang Z, Appathurai S, Mariappan M. A functional link between the co-translational protein translocation pathway and the UPR. elife. 2015;4: pubmed publisher
  103. Sheng X, Arnoldussen Y, Storm M, Tesikova M, Nenseth H, Zhao S, et al. Divergent androgen regulation of unfolded protein response pathways drives prostate cancer. EMBO Mol Med. 2015;7:788-801 pubmed publisher
  104. Wong M, Nicholson C, Holloway A, Hardy D. Maternal nicotine exposure leads to impaired disulfide bond formation and augmented endoplasmic reticulum stress in the rat placenta. PLoS ONE. 2015;10:e0122295 pubmed publisher
  105. Dametto P, Lakkaraju A, Bridel C, Villiger L, O CONNOR T, Herrmann U, et al. Neurodegeneration and unfolded-protein response in mice expressing a membrane-tethered flexible tail of PrP. PLoS ONE. 2015;10:e0117412 pubmed publisher
  106. Deegan S, Koryga I, Glynn S, Gupta S, Gorman A, Samali A. A close connection between the PERK and IRE arms of the UPR and the transcriptional regulation of autophagy. Biochem Biophys Res Commun. 2015;456:305-11 pubmed publisher
  107. Le Pape S, Dimitrova E, Hannaert P, Konovalov A, Volmer R, Ron D, et al. Polynomial algebra reveals diverging roles of the unfolded protein response in endothelial cells during ischemia-reperfusion injury. FEBS Lett. 2014;588:3062-7 pubmed publisher
  108. Maas N, Singh N, Diehl J. Generation and characterization of an analog-sensitive PERK allele. Cancer Biol Ther. 2014;15:1106-11 pubmed publisher
  109. Nagelkerke A, Sweep F, Stegeman H, Grenman R, Kaanders J, Bussink J, et al. Hypoxic regulation of the PERK/ATF4/LAMP3-arm of the unfolded protein response in head and neck squamous cell carcinoma. Head Neck. 2015;37:896-905 pubmed publisher
  110. Han J, Kaufman R. Measurement of the unfolded protein response to investigate its role in adipogenesis and obesity. Methods Enzymol. 2014;538:135-50 pubmed publisher
  111. Sisinni L, Maddalena F, Lettini G, Condelli V, Matassa D, Esposito F, et al. TRAP1 role in endoplasmic reticulum stress protection favors resistance to anthracyclins in breast carcinoma cells. Int J Oncol. 2014;44:573-82 pubmed publisher
  112. Peng Y, Shi Y, Ding Z, Ke A, Gu C, Hui B, et al. Autophagy inhibition suppresses pulmonary metastasis of HCC in mice via impairing anoikis resistance and colonization of HCC cells. Autophagy. 2013;9:2056-68 pubmed publisher
  113. Ma T, Trinh M, Wexler A, Bourbon C, Gatti E, Pierre P, et al. Suppression of eIF2? kinases alleviates Alzheimer's disease-related plasticity and memory deficits. Nat Neurosci. 2013;16:1299-305 pubmed publisher
  114. Huang M, Sivagurunathan S, Ting S, Jansson P, Austin C, Kelly M, et al. Molecular and functional alterations in a mouse cardiac model of Friedreich ataxia: activation of the integrated stress response, eIF2? phosphorylation, and the induction of downstream targets. Am J Pathol. 2013;183:745-57 pubmed publisher
  115. Devi L, Ohno M. Mechanisms that lessen benefits of ?-secretase reduction in a mouse model of Alzheimer's disease. Transl Psychiatry. 2013;3:e284 pubmed publisher