This is a Validated Antibody Database (VAD) review about human PELI1, based on 4 published articles (read how Labome selects the articles), using PELI1 antibody in all methods. It is aimed to help Labome visitors find the most suited PELI1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
PELI1 synonym: E3 ubiquitin-protein ligase pellino homolog 1; RING-type E3 ubiquitin transferase pellino homolog 1; pellino homolog 1; pellino-1; pellino-related intracellular-signaling molecule; protein pellino homolog 1

Knockout validation
Abcam
rabbit monoclonal (EPR19302)
  • western blot knockout validation; human; loading ...; fig 1e
  • immunocytochemistry; human; loading ...; fig 1g
Abcam PELI1 antibody (Abcam, ab199336) was used in western blot knockout validation on human samples (fig 1e) and in immunocytochemistry on human samples (fig 1g). Proc Natl Acad Sci U S A (2017) ncbi
Abcam
rabbit monoclonal (EPR19302)
  • western blot knockout validation; human; loading ...; fig 1e
  • immunocytochemistry; human; loading ...; fig 1g
Abcam PELI1 antibody (Abcam, ab199336) was used in western blot knockout validation on human samples (fig 1e) and in immunocytochemistry on human samples (fig 1g). Proc Natl Acad Sci U S A (2017) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 4a
In order to discover that Bid is a positive regulator of mutant SOD1-induced Toll like receptor-nuclear factor-kappa-b signaling in microglia, Abcam PELI1 antibody (Abcam, ab13812) was used in western blot on mouse samples at 1:1000 (fig 4a). Eneuro (2016) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000
Abcam PELI1 antibody (Abcam, ab13812) was used in western blot on mouse samples at 1:1000. Carcinogenesis (2013) ncbi
Santa Cruz Biotechnology
mouse monoclonal (F-7)
  • western blot; mouse; loading ...; fig 6g
Santa Cruz Biotechnology PELI1 antibody (Santa, SC-271065) was used in western blot on mouse samples (fig 6g). Nat Commun (2018) ncbi
Articles Reviewed
  1. Liu J, Huang X, Hao S, Wang Y, Liu M, Xu J, et al. Peli1 negatively regulates noncanonical NF-κB signaling to restrain systemic lupus erythematosus. Nat Commun. 2018;9:1136 pubmed publisher
  2. Wang H, Meng H, Li X, Zhu K, Dong K, Mookhtiar A, et al. PELI1 functions as a dual modulator of necroptosis and apoptosis by regulating ubiquitination of RIPK1 and mRNA levels of c-FLIP. Proc Natl Acad Sci U S A. 2017;114:11944-11949 pubmed publisher
  3. Kinsella S, König H, Prehn J. Bid Promotes K63-Linked Polyubiquitination of Tumor Necrosis Factor Receptor Associated Factor 6 (TRAF6) and Sensitizes to Mutant SOD1-Induced Proinflammatory Signaling in Microglia. Eneuro. 2016;3: pubmed publisher
  4. Ma X, Choudhury S, Hua X, Dai Z, Li Y. Interaction of the oncogenic miR-21 microRNA and the p53 tumor suppressor pathway. Carcinogenesis. 2013;34:1216-23 pubmed publisher