This is a Validated Antibody Database (VAD) review about human PDHA1, based on 49 published articles (read how Labome selects the articles), using PDHA1 antibody in all methods. It is aimed to help Labome visitors find the most suited PDHA1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
PDHA1 synonym: PDHA; PDHAD; PDHCE1A; PHE1A

Knockout validation
Abcam
domestic rabbit monoclonal (EPR12200)
  • immunohistochemistry knockout validation; human; 1:100; loading ...; fig 1c
Abcam PDHA1 antibody (Abcam, ab177461) was used in immunohistochemistry knockout validation on human samples at 1:100 (fig 1c). Onco Targets Ther (2019) ncbi
Abcam
mouse monoclonal (8D10E6)
  • western blot knockout validation; human; loading ...; fig 3a
Abcam PDHA1 antibody (Abcam, ab110334) was used in western blot knockout validation on human samples (fig 3a). Oncotarget (2016) ncbi
Proteintech Group
domestic rabbit polyclonal
  • western blot knockout validation; mouse; 1:1000; fig 4a
Proteintech Group PDHA1 antibody (Proteintech, 18068-1-AP) was used in western blot knockout validation on mouse samples at 1:1000 (fig 4a). Nat Cell Biol (2018) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (C54G1)
  • western blot knockout validation; human; loading ...; fig 2c
  • immunohistochemistry - paraffin section; human; loading ...; fig 6a
Cell Signaling Technology PDHA1 antibody (Cell signaling, C54G1) was used in western blot knockout validation on human samples (fig 2c) and in immunohistochemistry - paraffin section on human samples (fig 6a). Oncotarget (2017) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (C54G1)
  • western blot knockout validation; human; loading ...; fig 3a
Cell Signaling Technology PDHA1 antibody (Cell Signaling Technology, C54G1) was used in western blot knockout validation on human samples (fig 3a). Oncotarget (2016) ncbi
Abcam
domestic rabbit monoclonal (EPR12200)
  • immunohistochemistry knockout validation; human; 1:100; loading ...; fig 1c
Abcam PDHA1 antibody (Abcam, ab177461) was used in immunohistochemistry knockout validation on human samples at 1:100 (fig 1c). Onco Targets Ther (2019) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; Drosophila melanogaster; 1:200; loading ...; fig s6g
Abcam PDHA1 antibody (Abcam, ab92696) was used in immunohistochemistry on Drosophila melanogaster samples at 1:200 (fig s6g). Cell (2019) ncbi
mouse monoclonal (8D10E6)
  • immunohistochemistry; Drosophila melanogaster; fig 4f
Abcam PDHA1 antibody (Abcam, ab110334) was used in immunohistochemistry on Drosophila melanogaster samples (fig 4f). Nature (2019) ncbi
domestic rabbit monoclonal (EPR12200)
  • western blot; mouse; 1:1000; fig 5c
Abcam PDHA1 antibody (Abcam, ab177461) was used in western blot on mouse samples at 1:1000 (fig 5c). Nat Cell Biol (2018) ncbi
domestic rabbit monoclonal (EPR11098)
  • immunocytochemistry; human; loading ...; fig 5b
  • western blot; human; loading ...; fig 7c
Abcam PDHA1 antibody (Abcam, ab168379) was used in immunocytochemistry on human samples (fig 5b) and in western blot on human samples (fig 7c). J Biol Chem (2017) ncbi
mouse monoclonal (9H9AF5)
  • western blot; mouse; 1:1000; loading ...; fig s2n
Abcam PDHA1 antibody (Abcam, ab110330) was used in western blot on mouse samples at 1:1000 (fig s2n). Nature (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig s2n
Abcam PDHA1 antibody (Abcam, ab92696) was used in western blot on mouse samples at 1:1000 (fig s2n). Nature (2017) ncbi
mouse monoclonal (8D10E6)
  • other; Drosophila melanogaster; 1:500; loading ...; fig 4c
  • western blot; Drosophila melanogaster; 1:1000; fig s2
Abcam PDHA1 antibody (Abcam, ab110334) was used in other on Drosophila melanogaster samples at 1:500 (fig 4c) and in western blot on Drosophila melanogaster samples at 1:1000 (fig s2). Sci Rep (2017) ncbi
mouse monoclonal (9H9AF5)
  • western blot; mouse; loading ...; fig 7f
In order to identify posttranscriptional mechanisms that regulate mitochondrial protein expression, Abcam PDHA1 antibody (Abcam, ab110330) was used in western blot on mouse samples (fig 7f). J Cell Biol (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 6c
In order to examine whether proteins of energy metabolism can be used as biomarkers of inflammatory myopathies, Abcam PDHA1 antibody (Abcam, ab92696) was used in western blot on human samples at 1:1000 (fig 6c). J Transl Med (2017) ncbi
mouse monoclonal (8D10E6)
  • immunohistochemistry; mouse; 1:100; loading ...; fig 3k
In order to demonstrate that some mitochondrial enzymes associated with the tricarboxylic acid cycle are essential for epigenetic remodeling and transiently localize to the nucleus, Abcam PDHA1 antibody (Abcam, ab110334) was used in immunohistochemistry on mouse samples at 1:100 (fig 3k). Cell (2017) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:50; loading ...; fig 3g
In order to demonstrate that some mitochondrial enzymes associated with the tricarboxylic acid cycle are essential for epigenetic remodeling and transiently localize to the nucleus, Abcam PDHA1 antibody (Abcam, ab92696) was used in immunohistochemistry on mouse samples at 1:50 (fig 3g). Cell (2017) ncbi
mouse monoclonal (8D10E6)
  • western blot knockout validation; human; loading ...; fig 3a
Abcam PDHA1 antibody (Abcam, ab110334) was used in western blot knockout validation on human samples (fig 3a). Oncotarget (2016) ncbi
domestic rabbit monoclonal (EPR12200)
  • western blot; human; loading ...; fig 3k
Abcam PDHA1 antibody (Abcam, Ab177461) was used in western blot on human samples (fig 3k). Mol Metab (2016) ncbi
mouse monoclonal (8D10E6)
  • western blot; human; loading ...; fig 3k
Abcam PDHA1 antibody (Abcam, Ab110334) was used in western blot on human samples (fig 3k). Mol Metab (2016) ncbi
mouse monoclonal (9H9AF5)
  • western blot; mouse; 1:1000; loading ...; fig 1b
Abcam PDHA1 antibody (Abcam, ab110330) was used in western blot on mouse samples at 1:1000 (fig 1b). PLoS ONE (2016) ncbi
domestic rabbit monoclonal (EPR12200)
  • western blot; mouse; 1:10,000; loading ...; fig 1b
Abcam PDHA1 antibody (Abcam, ab177461) was used in western blot on mouse samples at 1:10,000 (fig 1b). PLoS ONE (2016) ncbi
domestic rabbit monoclonal (EPR12200)
  • western blot; human; fig 5b
In order to investigate the effect of nifurtimox on tumor metabolism, Abcam PDHA1 antibody (Abcam, ab177461) was used in western blot on human samples (fig 5b). Cancer Biol Ther (2015) ncbi
mouse monoclonal (8D10E6)
  • immunohistochemistry; Drosophila melanogaster
Abcam PDHA1 antibody (Abcam, ab110334) was used in immunohistochemistry on Drosophila melanogaster samples . Nat Cell Biol (2015) ncbi
mouse monoclonal (8D10E6)
  • western blot; mouse
Abcam PDHA1 antibody (Abcam, ab110334) was used in western blot on mouse samples . J Immunol (2014) ncbi
Invitrogen
mouse monoclonal (9H9AF5)
  • western blot; human; loading ...; fig 4b
Invitrogen PDHA1 antibody (Thermo Fisher Scientific, 459400) was used in western blot on human samples (fig 4b). Cell Rep (2019) ncbi
mouse monoclonal (9H9AF5)
  • western blot; human; 1:500; loading ...; fig 6c
In order to examine whether proteins of energy metabolism can be used as biomarkers of inflammatory myopathies, Invitrogen PDHA1 antibody (Invitrogen, 459400) was used in western blot on human samples at 1:500 (fig 6c). J Transl Med (2017) ncbi
mouse monoclonal (9H9AF5)
  • western blot; mouse; loading ...; fig 4a
In order to report the effects of taurine administration on glycogen repletion and carbohydrate metabolism in the tibialis anterior muscle after endurance exercise, Invitrogen PDHA1 antibody (Invitrogen, 459400) was used in western blot on mouse samples (fig 4a). J Nutr Sci Vitaminol (Tokyo) (2016) ncbi
mouse monoclonal (9H9AF5)
  • western blot; mouse; loading ...
In order to show that E4F1 regulates pyruvate metabolism to maintain skin homeostasis, Invitrogen PDHA1 antibody (Life technologies, 459400) was used in western blot on mouse samples . Proc Natl Acad Sci U S A (2016) ncbi
mouse monoclonal (9H9AF5)
  • western blot; human; loading ...; fig 3e
In order to determine the role of reductive stress in mitochondrial pathogenesis, Invitrogen PDHA1 antibody (Invitrogen, 459400) was used in western blot on human samples (fig 3e). Science (2016) ncbi
mouse monoclonal (9H9AF5)
  • western blot; human; fig s2
In order to study the support of redox homeostasis during anchorage-independent growth by reductive carboxylation, Invitrogen PDHA1 antibody (Thermo Scientific, 459400) was used in western blot on human samples (fig s2). Nature (2016) ncbi
mouse monoclonal (9H9AF5)
  • western blot; mouse
In order to elucidate the mechanisms by which KRAS mutations contribute to lung cancer, Invitrogen PDHA1 antibody (Life Technologies, 459400) was used in western blot on mouse samples . Nature (2016) ncbi
mouse monoclonal (9H9AF5)
  • western blot; human
In order to discuss the metabolic programs that drive tumorigenesis, Invitrogen PDHA1 antibody (Invitrogen, 459400) was used in western blot on human samples . Neuro Oncol (2015) ncbi
mouse monoclonal (8D10E6)
  • western blot; mouse; 1:750; fig 2
In order to test if drugs that alter mitochondrial metabolism also modulate amyotrophic lateral sclerosis progression, Invitrogen PDHA1 antibody (Invitrogen, 456600) was used in western blot on mouse samples at 1:750 (fig 2). PLoS ONE (2012) ncbi
mouse monoclonal (9H9AF5)
  • western blot; human; 1:500; fig 6
In order to test if switching the metabolism from glycolysis towards mitochondrial respiration reduces the growth of colorectal cancer cells and explore the mechanism, Invitrogen PDHA1 antibody (Invitrogen, 459400) was used in western blot on human samples at 1:500 (fig 6). Br J Cancer (2010) ncbi
Santa Cruz Biotechnology
mouse monoclonal (D-6)
  • western blot; mouse; 1:1000; loading ...; fig 4s2c
Santa Cruz Biotechnology PDHA1 antibody (Santa Cruz Biotechnology, SC-377092) was used in western blot on mouse samples at 1:1000 (fig 4s2c). elife (2019) ncbi
mouse monoclonal (D-6)
  • western blot; human; loading ...; fig 2b
Santa Cruz Biotechnology PDHA1 antibody (Santa, sc-377092) was used in western blot on human samples (fig 2b). Autophagy (2019) ncbi
mouse monoclonal (D-6)
  • immunohistochemistry; mouse; 1:50; loading ...; fig 3h
In order to demonstrate that some mitochondrial enzymes associated with the tricarboxylic acid cycle are essential for epigenetic remodeling and transiently localize to the nucleus, Santa Cruz Biotechnology PDHA1 antibody (Santa Cruz, sc-377092) was used in immunohistochemistry on mouse samples at 1:50 (fig 3h). Cell (2017) ncbi
mouse monoclonal (D-6)
  • western blot; human; loading ...; fig 4b
Santa Cruz Biotechnology PDHA1 antibody (Santa Cruz, sc-377092) was used in western blot on human samples (fig 4b). Oncotarget (2016) ncbi
mouse monoclonal (D-6)
  • western blot; human; fig 4b
In order to study mechanisms by which chronic beta2-adrenergic stimulation enhances muscle force and power output during maximal cycle ergometer exercise in young men, Santa Cruz Biotechnology PDHA1 antibody (Santa Cruz Biotechnology, sc-377092) was used in western blot on human samples (fig 4b). J Appl Physiol (1985) (2015) ncbi
Proteintech Group
domestic rabbit polyclonal
  • western blot knockout validation; mouse; 1:1000; fig 4a
Proteintech Group PDHA1 antibody (Proteintech, 18068-1-AP) was used in western blot knockout validation on mouse samples at 1:1000 (fig 4a). Nat Cell Biol (2018) ncbi
mouse monoclonal (2B3C10)
  • western blot; human; loading ...; fig s3j
Proteintech Group PDHA1 antibody (ProteinTech, 66119-1-Ig) was used in western blot on human samples (fig s3j). J Cell Biol (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 3e
Proteintech Group PDHA1 antibody (Proteintech, 18068) was used in western blot on mouse samples (fig 3e). Cell Metab (2016) ncbi
Novus Biologicals
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 2a, 3b
Novus Biologicals PDHA1 antibody (Novus, NB110-93479) was used in western blot on human samples at 1:1000 (fig 2a, 3b). Oncogenesis (2020) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; fig s4e
Novus Biologicals PDHA1 antibody (Novus Biological, NB110-93479) was used in western blot on human samples at 1:1000 (fig s4e). Nat Cell Biol (2018) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 5a
In order to research the role of ORP4L for T-cell acute lymphoblastic leukemia cell survival, Novus Biologicals PDHA1 antibody (Novus Biologicals, NB110?C93479) was used in western blot on human samples at 1:1000 (fig 5a). Nat Commun (2016) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (C54G1)
  • western blot; human; 1:1000; loading ...; fig 2a, 3b
Cell Signaling Technology PDHA1 antibody (Cell Signaling, 3205) was used in western blot on human samples at 1:1000 (fig 2a, 3b). Oncogenesis (2020) ncbi
domestic rabbit monoclonal (C54G1)
  • western blot; human; loading ...; fig 3f
Cell Signaling Technology PDHA1 antibody (Cell Signaling, 3205) was used in western blot on human samples (fig 3f). Cell (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 2f, e2e
Cell Signaling Technology PDHA1 antibody (Cell Signaling, 2784) was used in western blot on human samples (fig 2f, e2e). Nature (2019) ncbi
domestic rabbit monoclonal (C54G1)
  • western blot; human; fig 5f
Cell Signaling Technology PDHA1 antibody (Cell Signaling, 3205) was used in western blot on human samples (fig 5f). Sci Rep (2017) ncbi
domestic rabbit monoclonal (C54G1)
  • western blot; human; loading ...; fig 5e
Cell Signaling Technology PDHA1 antibody (Cell Signaling, 3205) was used in western blot on human samples (fig 5e). Sci Rep (2017) ncbi
domestic rabbit monoclonal (C54G1)
  • western blot knockout validation; human; loading ...; fig 2c
  • immunohistochemistry - paraffin section; human; loading ...; fig 6a
Cell Signaling Technology PDHA1 antibody (Cell signaling, C54G1) was used in western blot knockout validation on human samples (fig 2c) and in immunohistochemistry - paraffin section on human samples (fig 6a). Oncotarget (2017) ncbi
domestic rabbit monoclonal (C54G1)
  • western blot; human; fig 7
In order to describe the effects of long- and short-term exposure to erythropoietin on white adipose tissue, Cell Signaling Technology PDHA1 antibody (Cell signaling, 3205) was used in western blot on human samples (fig 7). Lipids Health Dis (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 5a
In order to research the role of ORP4L for T-cell acute lymphoblastic leukemia cell survival, Cell Signaling Technology PDHA1 antibody (cell signalling, 2784) was used in western blot on human samples at 1:1000 (fig 5a). Nat Commun (2016) ncbi
domestic rabbit monoclonal (C54G1)
  • western blot; mouse; loading ...; fig 3g
In order to test if LKB1 mutations contribute to cervical cancer initiation and progress, Cell Signaling Technology PDHA1 antibody (Cell signaling, 3205) was used in western blot on mouse samples (fig 3g). Oncogene (2017) ncbi
domestic rabbit monoclonal (C54G1)
  • western blot knockout validation; human; loading ...; fig 3a
Cell Signaling Technology PDHA1 antibody (Cell Signaling Technology, C54G1) was used in western blot knockout validation on human samples (fig 3a). Oncotarget (2016) ncbi
domestic rabbit monoclonal (C54G1)
  • western blot; human; fig 3
Cell Signaling Technology PDHA1 antibody (Cell Signaling, C54G1) was used in western blot on human samples (fig 3). Sci Rep (2016) ncbi
domestic rabbit monoclonal (C54G1)
  • western blot; human; 1:1000; loading ...; tbl 1
In order to examine the effect of ghrelin in human Sertoli cells metabolism, Cell Signaling Technology PDHA1 antibody (Cell Signaling, 3205) was used in western blot on human samples at 1:1000 (tbl 1). Mol Cell Endocrinol (2016) ncbi
domestic rabbit monoclonal (C54G1)
  • western blot; mouse; 1:1000; loading ...; fig 1c
In order to develop a method to assess mitochondrial pyruvate carrier activity, Cell Signaling Technology PDHA1 antibody (Cell Signaling, 3205S) was used in western blot on mouse samples at 1:1000 (fig 1c). J Biol Chem (2016) ncbi
domestic rabbit monoclonal (C54G1)
  • western blot; rat; 1:1000; fig 8
In order to investigate thyroid hormone-mediated autophagy in skeletal muscle, Cell Signaling Technology PDHA1 antibody (Cell Signaling Technology, 3205) was used in western blot on rat samples at 1:1000 (fig 8). Endocrinology (2016) ncbi
domestic rabbit monoclonal (C54G1)
  • western blot; human; 1:1000; loading ...; fig 4b
Cell Signaling Technology PDHA1 antibody (Cell Signaling, 3205) was used in western blot on human samples at 1:1000 (fig 4b). Oncotarget (2015) ncbi
domestic rabbit monoclonal (C54G1)
  • western blot; rat; 1:10000
In order to investigate the role of mitochondria-associated miRNAs in traumatic brain injury, Cell Signaling Technology PDHA1 antibody (Cell Signaling, 3205) was used in western blot on rat samples at 1:10000. Exp Neurol (2015) ncbi
domestic rabbit monoclonal (C54G1)
  • western blot; mouse; fig 2
Cell Signaling Technology PDHA1 antibody (Cell Signaling Tech, 3205) was used in western blot on mouse samples (fig 2). Autophagy (2014) ncbi
EMD Millipore
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 2a
In order to report that E4F1 is a master regulator of the pyruvate dehydrogenase complex, EMD Millipore PDHA1 antibody (Millipore, ABS 204) was used in western blot on mouse samples (fig 2a). Proc Natl Acad Sci U S A (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 3e
In order to determine the role of reductive stress in mitochondrial pathogenesis, EMD Millipore PDHA1 antibody (EMD Millipore, AP1064) was used in western blot on human samples (fig 3e). Science (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig s2
In order to study the support of redox homeostasis during anchorage-independent growth by reductive carboxylation, EMD Millipore PDHA1 antibody (Millipore, AP1062) was used in western blot on human samples (fig s2). Nature (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 3e
EMD Millipore PDHA1 antibody (Calbiochem, AP1062) was used in western blot on mouse samples (fig 3e). Cell Metab (2016) ncbi
Articles Reviewed
  1. Siu M, Jiang Y, Wang J, Leung T, Ngu S, Cheung A, et al. PDK1 promotes ovarian cancer metastasis by modulating tumor-mesothelial adhesion, invasion, and angiogenesis via α5β1 integrin and JNK/IL-8 signaling. Oncogenesis. 2020;9:24 pubmed publisher
  2. Liu L, Cao J, Zhao J, Li X, Suo Z, Li H. PDHA1 Gene Knockout In Human Esophageal Squamous Cancer Cells Resulted In Greater Warburg Effect And Aggressive Features In Vitro And In Vivo. Onco Targets Ther. 2019;12:9899-9913 pubmed publisher
  3. Hudry B, de Goeij E, Mineo A, Gaspar P, Hadjieconomou D, Studd C, et al. Sex Differences in Intestinal Carbohydrate Metabolism Promote Food Intake and Sperm Maturation. Cell. 2019;178:901-918.e16 pubmed publisher
  4. Sharma A, Oonthonpan L, Sheldon R, Rauckhorst A, Zhu Z, Tompkins S, et al. Impaired skeletal muscle mitochondrial pyruvate uptake rewires glucose metabolism to drive whole-body leanness. elife. 2019;8: pubmed publisher
  5. Park S, Safi R, Liu X, Baldi R, Liu W, Liu J, et al. Inhibition of ERRα Prevents Mitochondrial Pyruvate Uptake Exposing NADPH-Generating Pathways as Targetable Vulnerabilities in Breast Cancer. Cell Rep. 2019;27:3587-3601.e4 pubmed publisher
  6. Zhang W, Wang G, Xu Z, Tu H, Hu F, Dai J, et al. Lactate Is a Natural Suppressor of RLR Signaling by Targeting MAVS. Cell. 2019;: pubmed publisher
  7. Lieber T, Jeedigunta S, Palozzi J, Lehmann R, Hurd T. Mitochondrial fragmentation drives selective removal of deleterious mtDNA in the germline. Nature. 2019;: pubmed publisher
  8. Lee J, Yesilkanal A, Wynne J, Frankenberger C, Liu J, Yan J, et al. Effective breast cancer combination therapy targeting BACH1 and mitochondrial metabolism. Nature. 2019;568:254-258 pubmed publisher
  9. Huang X, Gan G, Wang X, Xu T, Xie W. The HGF-MET axis coordinates liver cancer metabolism and autophagy for chemotherapeutic resistance. Autophagy. 2019;15:1258-1279 pubmed publisher
  10. Chhipa R, Fan Q, Anderson J, Muraleedharan R, Huang Y, Ciraolo G, et al. AMP kinase promotes glioblastoma bioenergetics and tumour growth. Nat Cell Biol. 2018;20:823-835 pubmed publisher
  11. Yang Z, Wang Y, Zhang Y, He X, Zhong C, Ni H, et al. RIP3 targets pyruvate dehydrogenase complex to increase aerobic respiration in TNF-induced necroptosis. Nat Cell Biol. 2018;20:186-197 pubmed publisher
  12. Kumazoe M, Takai M, Hiroi S, Takeuchi C, Kadomatsu M, Nojiri T, et al. The FOXO3/PGC-1? signaling axis is essential for cancer stem cell properties of pancreatic ductal adenocarcinoma. J Biol Chem. 2017;292:10813-10823 pubmed publisher
  13. Luongo T, Lambert J, Gross P, Nwokedi M, Lombardi A, Shanmughapriya S, et al. The mitochondrial Na+/Ca2+ exchanger is essential for Ca2+ homeostasis and viability. Nature. 2017;545:93-97 pubmed publisher
  14. Zhao X, Sun K, Lan Z, Song W, Cheng L, Chi W, et al. Tenofovir and adefovir down-regulate mitochondrial chaperone TRAP1 and succinate dehydrogenase subunit B to metabolically reprogram glucose metabolism and induce nephrotoxicity. Sci Rep. 2017;7:46344 pubmed publisher
  15. Jiang Y, Lin S, Chen J, Tsai H, Hsieh T, Fu C. Electron tomographic analysis reveals ultrastructural features of mitochondrial cristae architecture which reflect energetic state and aging. Sci Rep. 2017;7:45474 pubmed publisher
  16. Møller A, Kampmann U, Hedegaard J, Thorsen K, Nordentoft I, Vendelbo M, et al. Altered gene expression and repressed markers of autophagy in skeletal muscle of insulin resistant patients with type 2 diabetes. Sci Rep. 2017;7:43775 pubmed publisher
  17. Schatton D, Pla Martín D, Marx M, Hansen H, Mourier A, Nemazanyy I, et al. CLUH regulates mitochondrial metabolism by controlling translation and decay of target mRNAs. J Cell Biol. 2017;216:675-693 pubmed publisher
  18. Santacatterina F, Sánchez Aragó M, Catalán García M, Garrabou G, de Arenas C, Grau J, et al. Pyruvate kinase M2 and the mitochondrial ATPase Inhibitory Factor 1 provide novel biomarkers of dermatomyositis: a metabolic link to oncogenesis. J Transl Med. 2017;15:29 pubmed publisher
  19. Nagaraj R, Sharpley M, Chi F, Braas D, Zhou Y, Kim R, et al. Nuclear Localization of Mitochondrial TCA Cycle Enzymes as a Critical Step in Mammalian Zygotic Genome Activation. Cell. 2017;168:210-223.e11 pubmed publisher
  20. Zhong Y, Li X, Ji Y, Li X, Li Y, Yu D, et al. Pyruvate dehydrogenase expression is negatively associated with cell stemness and worse clinical outcome in prostate cancers. Oncotarget. 2017;8:13344-13356 pubmed publisher
  21. Takahashi Y, Tamura Y, Matsunaga Y, Kitaoka Y, Terada S, Hatta H. Effects of Taurine Administration on Carbohydrate Metabolism in Skeletal Muscle during the Post-Exercise Phase. J Nutr Sci Vitaminol (Tokyo). 2016;62:257-264 pubmed
  22. Christensen B, Nellemann B, Jørgensen J, Pedersen S, Jessen N. Erythropoietin does not activate erythropoietin receptor signaling or lipolytic pathways in human subcutaneous white adipose tissue in vivo. Lipids Health Dis. 2016;15:160 pubmed publisher
  23. Lacroix M, Rodier G, Kirsh O, Houles T, Delpech H, Seyran B, et al. E4F1 controls a transcriptional program essential for pyruvate dehydrogenase activity. Proc Natl Acad Sci U S A. 2016;113:10998-1003 pubmed publisher
  24. Goguet Rubio P, Seyran B, Gayte L, Bernex F, Sutter A, Delpech H, et al. E4F1-mediated control of pyruvate dehydrogenase activity is essential for skin homeostasis. Proc Natl Acad Sci U S A. 2016;113:11004-9 pubmed publisher
  25. Zhong W, Yi Q, Xu B, Li S, Wang T, Liu F, et al. ORP4L is essential for T-cell acute lymphoblastic leukemia cell survival. Nat Commun. 2016;7:12702 pubmed publisher
  26. Zeng Q, Chen J, Li Y, Werle K, Zhao R, Quan C, et al. LKB1 inhibits HPV-associated cancer progression by targeting cellular metabolism. Oncogene. 2017;36:1245-1255 pubmed publisher
  27. Li Y, Li X, Li X, Zhong Y, Ji Y, Yu D, et al. PDHA1 gene knockout in prostate cancer cells results in metabolic reprogramming towards greater glutamine dependence. Oncotarget. 2016;7:53837-53852 pubmed publisher
  28. Ma T, Fan B, Zhang C, Zhao H, Han C, Gao C, et al. Metabonomics applied in exploring the antitumour mechanism of physapubenolide on hepatocellular carcinoma cells by targeting glycolysis through the Akt-p53 pathway. Sci Rep. 2016;6:29926 pubmed publisher
  29. Martins A, Sá R, Monteiro M, Barros A, Sousa M, Carvalho R, et al. Ghrelin acts as energy status sensor of male reproduction by modulating Sertoli cells glycolytic metabolism and mitochondrial bioenergetics. Mol Cell Endocrinol. 2016;434:199-209 pubmed publisher
  30. Yin C, He D, Chen S, Tan X, Sang N. Exogenous pyruvate facilitates cancer cell adaptation to hypoxia by serving as an oxygen surrogate. Oncotarget. 2016;7:47494-47510 pubmed publisher
  31. Titov D, Cracan V, Goodman R, Peng J, Grabarek Z, Mootha V. Complementation of mitochondrial electron transport chain by manipulation of the NAD+/NADH ratio. Science. 2016;352:231-5 pubmed publisher
  32. Barquissau V, Beuzelin D, Pisani D, Beranger G, Mairal A, Montagner A, et al. White-to-brite conversion in human adipocytes promotes metabolic reprogramming towards fatty acid anabolic and catabolic pathways. Mol Metab. 2016;5:352-365 pubmed publisher
  33. Pryde K, Smith H, Chau K, Schapira A. PINK1 disables the anti-fission machinery to segregate damaged mitochondria for mitophagy. J Cell Biol. 2016;213:163-71 pubmed publisher
  34. Jiang L, Shestov A, Swain P, Yang C, Parker S, Wang Q, et al. Reductive carboxylation supports redox homeostasis during anchorage-independent growth. Nature. 2016;532:255-8 pubmed publisher
  35. Zhang Y, Zhao Z, Ke B, Wan L, Wang H, Ye J. Induction of Posttranslational Modifications of Mitochondrial Proteins by ATP Contributes to Negative Regulation of Mitochondrial Function. PLoS ONE. 2016;11:e0150454 pubmed publisher
  36. Kerr E, Gaude E, Turrell F, Frezza C, Martins C. Mutant Kras copy number defines metabolic reprogramming and therapeutic susceptibilities. Nature. 2016;531:110-3 pubmed publisher
  37. Davidson S, Papagiannakopoulos T, Olenchock B, Heyman J, Keibler M, Luengo A, et al. Environment Impacts the Metabolic Dependencies of Ras-Driven Non-Small Cell Lung Cancer. Cell Metab. 2016;23:517-28 pubmed publisher
  38. Gray L, Rauckhorst A, Taylor E. A Method for Multiplexed Measurement of Mitochondrial Pyruvate Carrier Activity. J Biol Chem. 2016;291:7409-17 pubmed publisher
  39. Lesmana R, Sinha R, Singh B, Zhou J, Ohba K, Wu Y, et al. Thyroid Hormone Stimulation of Autophagy Is Essential for Mitochondrial Biogenesis and Activity in Skeletal Muscle. Endocrinology. 2016;157:23-38 pubmed publisher
  40. Cabanillas Stanchi K, Bruchelt G, Handgretinger R, Holzer U. Nifurtimox reduces N-Myc expression and aerobic glycolysis in neuroblastoma. Cancer Biol Ther. 2015;16:1353-63 pubmed publisher
  41. Hostrup M, Kalsen A, Onslev J, Jessen S, Haase C, Habib S, et al. Mechanisms underlying enhancements in muscle force and power output during maximal cycle ergometer exercise induced by chronic β2-adrenergic stimulation in men. J Appl Physiol (1985). 2015;119:475-86 pubmed publisher
  42. Loureiro R, Magalhães Novais S, Mesquita K, Baldeiras I, Sousa I, Tavares L, et al. Melatonin antiproliferative effects require active mitochondrial function in embryonal carcinoma cells. Oncotarget. 2015;6:17081-96 pubmed
  43. Teixeira F, Sanchez C, Hurd T, Seifert J, Czech B, Preall J, et al. ATP synthase promotes germ cell differentiation independent of oxidative phosphorylation. Nat Cell Biol. 2015;17:689-96 pubmed publisher
  44. Prabhu A, Sarcar B, Miller C, Kim S, Nakano I, Forsyth P, et al. Ras-mediated modulation of pyruvate dehydrogenase activity regulates mitochondrial reserve capacity and contributes to glioblastoma tumorigenesis. Neuro Oncol. 2015;17:1220-30 pubmed publisher
  45. Wang W, Visavadiya N, Pandya J, Nelson P, Sullivan P, Springer J. Mitochondria-associated microRNAs in rat hippocampus following traumatic brain injury. Exp Neurol. 2015;265:84-93 pubmed publisher
  46. Caro Maldonado A, Wang R, Nichols A, Kuraoka M, Milasta S, Sun L, et al. Metabolic reprogramming is required for antibody production that is suppressed in anergic but exaggerated in chronically BAFF-exposed B cells. J Immunol. 2014;192:3626-36 pubmed publisher
  47. Furuya N, Ikeda S, Sato S, Soma S, Ezaki J, Oliva Trejo J, et al. PARK2/Parkin-mediated mitochondrial clearance contributes to proteasome activation during slow-twitch muscle atrophy via NFE2L1 nuclear translocation. Autophagy. 2014;10:631-41 pubmed publisher
  48. Miquel E, Cassina A, Martinez Palma L, Bolatto C, Trias E, Gandelman M, et al. Modulation of astrocytic mitochondrial function by dichloroacetate improves survival and motor performance in inherited amyotrophic lateral sclerosis. PLoS ONE. 2012;7:e34776 pubmed publisher
  49. Madhok B, Yeluri S, Perry S, Hughes T, Jayne D. Dichloroacetate induces apoptosis and cell-cycle arrest in colorectal cancer cells. Br J Cancer. 2010;102:1746-52 pubmed publisher