This is a Validated Antibody Database (VAD) review about human PDE4A, based on 7 published articles (read how Labome selects the articles), using PDE4A antibody in all methods. It is aimed to help Labome visitors find the most suited PDE4A antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
PDE4A synonym: DPDE2; PDE4; PDE46; cAMP-specific 3',5'-cyclic phosphodiesterase 4A; phosphodiesterase 4A, cAMP-specific (dunce; phosphodiesterase E2 dunce homolog, Drosophila; phosphodiesterase isozyme 4

Abcam
rabbit polyclonal
  • western blot; human; fig 2
Abcam PDE4A antibody (Abcam, ab14628) was used in western blot on human samples (fig 2). Cell Death Dis (2016) ncbi
rabbit polyclonal
  • western blot; rat; 1:2000; fig 1
Abcam PDE4A antibody (Abcam, ab42094) was used in western blot on rat samples at 1:2000 (fig 1). Front Syst Neurosci (2016) ncbi
rabbit polyclonal
  • immunohistochemistry - frozen section; Rhesus monkey; 1:300; loading ...; fig 4
  • western blot; Rhesus monkey; loading ...; fig 5a
  • western blot; mouse; loading ...; fig s6a
Abcam PDE4A antibody (Abcam, ab14607) was used in immunohistochemistry - frozen section on Rhesus monkey samples at 1:300 (fig 4), in western blot on Rhesus monkey samples (fig 5a) and in western blot on mouse samples (fig s6a). Proc Natl Acad Sci U S A (2014) ncbi
rabbit polyclonal
  • western blot; human; 1:500
Abcam PDE4A antibody (Abcam, ab14607) was used in western blot on human samples at 1:500. Mediators Inflamm (2013) ncbi
rabbit polyclonal
  • western blot; mouse
Abcam PDE4A antibody (Abcam, ab14607) was used in western blot on mouse samples . Br J Pharmacol (2013) ncbi
rabbit polyclonal
  • western blot; rat; 1:2000
Abcam PDE4A antibody (Abcam, ab42094) was used in western blot on rat samples at 1:2000. J Neurochem (2012) ncbi
Santa Cruz Biotechnology
mouse monoclonal (H-7)
  • immunohistochemistry - paraffin section; human; loading ...; fig 5b
Santa Cruz Biotechnology PDE4A antibody (Santa Cruz, SC-74428) was used in immunohistochemistry - paraffin section on human samples (fig 5b). BMC Cancer (2016) ncbi
Articles Reviewed
  1. Mahmood B, Damm M, Jensen T, Backe M, Dahllöf M, Poulsen S, et al. Phosphodiesterases in non-neoplastic appearing colonic mucosa from patients with colorectal neoplasia. BMC Cancer. 2016;16:938 pubmed
  2. Taniguchi T, Iizumi Y, Watanabe M, Masuda M, Morita M, Aono Y, et al. Resveratrol directly targets DDX5 resulting in suppression of the mTORC1 pathway in prostate cancer. Cell Death Dis. 2016;7:e2211 pubmed publisher
  3. Wilson N, Titus D, Oliva A, Furones C, Atkins C. Traumatic Brain Injury Upregulates Phosphodiesterase Expression in the Hippocampus. Front Syst Neurosci. 2016;10:5 pubmed publisher
  4. Carlyle B, Nairn A, Wang M, Yang Y, Jin L, Simen A, et al. cAMP-PKA phosphorylation of tau confers risk for degeneration in aging association cortex. Proc Natl Acad Sci U S A. 2014;111:5036-41 pubmed publisher
  5. Fang Q, Ma Y, Wang J, Michalski J, Rennard S, Liu X. PGE 2 desensitizes ? -agonist effect on human lung fibroblast-mediated collagen gel contraction through upregulating PDE4. Mediators Inflamm. 2013;2013:145197 pubmed publisher
  6. Korhonen R, Hömmö T, Keränen T, Laavola M, Hamalainen M, Vuolteenaho K, et al. Attenuation of TNF production and experimentally induced inflammation by PDE4 inhibitor rolipram is mediated by MAPK phosphatase-1. Br J Pharmacol. 2013;169:1525-36 pubmed publisher
  7. Oliva A, Kang Y, Furones C, Alonso O, Bruno O, Dietrich W, et al. Phosphodiesterase isoform-specific expression induced by traumatic brain injury. J Neurochem. 2012;123:1019-29 pubmed publisher