This is a Validated Antibody Database (VAD) review about human PCSK9, based on 3 published articles (read how Labome selects the articles), using PCSK9 antibody in all methods. It is aimed to help Labome visitors find the most suited PCSK9 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
PCSK9 synonym: FH3; HCHOLA3; LDLCQ1; NARC-1; NARC1; PC9; proprotein convertase subtilisin/kexin type 9; convertase subtilisin/kexin type 9 preproprotein; neural apoptosis regulated convertase 1; subtilisin/kexin-like protease PC9

Abcam
rabbit monoclonal (EPR7627(2))
  • western blot; human; 1:3000; loading ...; fig 3a
Abcam PCSK9 antibody (Abcam, ab181142) was used in western blot on human samples at 1:3000 (fig 3a). Exp Ther Med (2017) ncbi
goat polyclonal
  • western blot; human; 0.5 ug/ml; fig 2
In order to test if proprotein convertase subtilisin/kexin type 9 modulates the levels of low-density lipoprotein receptor and other membrane-bound proteins in the adult mouse brain, Abcam PCSK9 antibody (Abcam, ab28770) was used in western blot on human samples at 0.5 ug/ml (fig 2). J Lipid Res (2010) ncbi
R&D Systems
sheep polyclonal
  • ELISA; human
R&D Systems PCSK9 antibody (R&D Systems, BAF3888) was used in ELISA on human samples . J Lipid Res (2014) ncbi
sheep polyclonal
  • ELISA; human
  • western blot; human
R&D Systems PCSK9 antibody (R&D Systems, AF3888) was used in ELISA on human samples and in western blot on human samples . J Lipid Res (2014) ncbi
Articles Reviewed
  1. Xu X, Cui Y, Cao L, Zhang Y, Yin Y, Hu X. PCSK9 regulates apoptosis in human lung adenocarcinoma A549 cells via endoplasmic reticulum stress and mitochondrial signaling pathways. Exp Ther Med. 2017;13:1993-1999 pubmed publisher
  2. Han B, Eacho P, Knierman M, Troutt J, Konrad R, Yu X, et al. Isolation and characterization of the circulating truncated form of PCSK9. J Lipid Res. 2014;55:1505-14 pubmed publisher
  3. Liu M, Wu G, Baysarowich J, Kavana M, Addona G, Bierilo K, et al. PCSK9 is not involved in the degradation of LDL receptors and BACE1 in the adult mouse brain. J Lipid Res. 2010;51:2611-8 pubmed publisher