This is a Validated Antibody Database (VAD) review about human PCK1, based on 12 published articles (read how Labome selects the articles), using PCK1 antibody in all methods. It is aimed to help Labome visitors find the most suited PCK1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
PCK1 synonym: PCKDC; PEPCK-C; PEPCK1; PEPCKC

Knockout validation
Abcam
domestic rabbit monoclonal
  • western blot knockout validation; human; fig 4b
  • immunohistochemistry; human; loading ...; fig 1f
Abcam PCK1 antibody (Abcam, ab133603) was used in western blot knockout validation on human samples (fig 4b) and in immunohistochemistry on human samples (fig 1f). Cell Death Dis (2021) ncbi
Santa Cruz Biotechnology
mouse monoclonal (F-3)
  • western blot; mouse; loading ...; fig 4i
Santa Cruz Biotechnology PCK1 antibody (Santa Cruz, sc-271029) was used in western blot on mouse samples (fig 4i). J Nutr Biochem (2021) ncbi
mouse monoclonal (F-3)
  • western blot; mouse; 1:1000; loading ...; fig 2e
Santa Cruz Biotechnology PCK1 antibody (Santa, sc-271029) was used in western blot on mouse samples at 1:1000 (fig 2e). Mol Metab (2020) ncbi
mouse monoclonal (E-1)
  • western blot; mouse; loading ...; fig 5
Santa Cruz Biotechnology PCK1 antibody (SantaCruz, sc-271204) was used in western blot on mouse samples (fig 5). J Physiol Sci (2018) ncbi
mouse monoclonal (F-2)
  • western blot; mouse; loading ...; fig 5b
In order to determine the role of forkhead box O1 in cannabinoid receptor type-mediated insulin resistance, Santa Cruz Biotechnology PCK1 antibody (Santa Cruz, 166778) was used in western blot on mouse samples (fig 5b). Int J Mol Med (2016) ncbi
mouse monoclonal (E-1)
  • western blot; rat; 1:200; loading ...; fig 3a
Santa Cruz Biotechnology PCK1 antibody (Santa Cruz, sc-271204) was used in western blot on rat samples at 1:200 (fig 3a). Mol Med Rep (2016) ncbi
mouse monoclonal (E-1)
  • western blot; mouse; fig 6
Santa Cruz Biotechnology PCK1 antibody (santa Cruz, SC271204) was used in western blot on mouse samples (fig 6). PLoS ONE (2015) ncbi
mouse monoclonal (F-11)
  • western blot; zebrafish ; 1:1000; fig 2
Santa Cruz Biotechnology PCK1 antibody (santa Cruz, sc-377027) was used in western blot on zebrafish samples at 1:1000 (fig 2). Int J Biol Sci (2015) ncbi
mouse monoclonal (G-9)
  • western blot; rat; 1:200; fig 6
Santa Cruz Biotechnology PCK1 antibody (Santa Cruz, sc-377136) was used in western blot on rat samples at 1:200 (fig 6). Nat Commun (2015) ncbi
Abcam
domestic rabbit monoclonal
  • western blot knockout validation; human; fig 4b
  • immunohistochemistry; human; loading ...; fig 1f
Abcam PCK1 antibody (Abcam, ab133603) was used in western blot knockout validation on human samples (fig 4b) and in immunohistochemistry on human samples (fig 1f). Cell Death Dis (2021) ncbi
Invitrogen
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 1g
In order to investigate the effect of testosterone supplementation on hepatic insulin responsiveness and glucose homeostasis through liver in male high-fat diet-induced type II diabetes mice, Invitrogen PCK1 antibody (Thermo Fischer, PA5-15364) was used in western blot on mouse samples (fig 1g). Nutr Diabetes (2016) ncbi
Abnova
mouse monoclonal (3E4)
  • western blot; mouse; loading ...; fig 1c
  • western blot; human; loading ...; fig 6a
Abnova PCK1 antibody (Abnova, H00005105-M01) was used in western blot on mouse samples (fig 1c) and in western blot on human samples (fig 6a). FASEB J (2014) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D12F5)
  • western blot; human; loading ...; fig 2a
In order to identify homologous to the E6-AP carboxyl terminus as a ubiquitin ligase for modulator of apoptosis protein 1, Cell Signaling Technology PCK1 antibody (Cell Signaling, 12940) was used in western blot on human samples (fig 2a). Oncogene (2017) ncbi
Articles Reviewed
  1. Zhu X, Peng S, Wang L, Chen X, Feng C, Liu Y, et al. Identification of phosphoenolpyruvate carboxykinase 1 as a potential therapeutic target for pancreatic cancer. Cell Death Dis. 2021;12:918 pubmed publisher
  2. Zhang G, Li R, Li W, Yang S, Sun Q, Yin H, et al. Toll-like receptor 3 ablation prevented high-fat diet-induced obesity and metabolic disorder. J Nutr Biochem. 2021;95:108761 pubmed publisher
  3. Xu M, Ge C, Qin Y, Lou D, Li Q, Feng J, et al. Functional loss of inactive rhomboid-like protein 2 mitigates obesity by suppressing pro-inflammatory macrophage activation-triggered adipose inflammation. Mol Metab. 2020;34:112-123 pubmed publisher
  4. Muñoz V, Gaspar R, Crisol B, Formigari G, Sant Ana M, Botezelli J, et al. Physical exercise reduces pyruvate carboxylase (PCB) and contributes to hyperglycemia reduction in obese mice. J Physiol Sci. 2018;68:493-501 pubmed publisher
  5. Pal M, Gupta S. Testosterone supplementation improves glucose homeostasis despite increasing hepatic insulin resistance in male mouse model of type 2 diabetes mellitus. Nutr Diabetes. 2016;6:e236 pubmed publisher
  6. Matsuura K, Huang N, Cocce K, Zhang L, Kornbluth S. Downregulation of the proapoptotic protein MOAP-1 by the UBR5 ubiquitin ligase and its role in ovarian cancer resistance to cisplatin. Oncogene. 2017;36:1698-1706 pubmed publisher
  7. Chen C, Lee T, Kwok C, Hsu Y, Shih K, Lin Y, et al. Cannabinoid receptor type 1 mediates high-fat diet-induced insulin resistance by increasing forkhead box O1 activity in a mouse model of obesity. Int J Mol Med. 2016;37:743-54 pubmed publisher
  8. Zhang H, Wang X, Wu Z, Liu H, Chen W, Zhang Z, et al. Beneficial effect of farnesoid X receptor activation on metabolism in a diabetic rat model. Mol Med Rep. 2016;13:2135-42 pubmed publisher
  9. da Rocha A, Pereira B, Pauli J, Cintra D, De Souza C, Ropelle E, et al. Downhill Running-Based Overtraining Protocol Improves Hepatic Insulin Signaling Pathway without Concomitant Decrease of Inflammatory Proteins. PLoS ONE. 2015;10:e0140020 pubmed publisher
  10. Furukawa F, Tseng Y, Liu S, Chou Y, Lin C, Sung P, et al. Induction of Phosphoenolpyruvate Carboxykinase (PEPCK) during Acute Acidosis and Its Role in Acid Secretion by V-ATPase-Expressing Ionocytes. Int J Biol Sci. 2015;11:712-25 pubmed publisher
  11. Perry R, Lee S, Ma L, Zhang D, Schlessinger J, Shulman G. FGF1 and FGF19 reverse diabetes by suppression of the hypothalamic-pituitary-adrenal axis. Nat Commun. 2015;6:6980 pubmed publisher
  12. Cicerchi C, Li N, Kratzer J, Garcia G, Roncal Jimenez C, Tanabe K, et al. Uric acid-dependent inhibition of AMP kinase induces hepatic glucose production in diabetes and starvation: evolutionary implications of the uricase loss in hominids. FASEB J. 2014;28:3339-50 pubmed publisher