This is a Validated Antibody Database (VAD) review about human PC2, based on 4 published articles (read how Labome selects the articles), using PC2 antibody in all methods. It is aimed to help Labome visitors find the most suited PC2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
PC2 synonym: NEC 2; NEC-2; NEC2; PC2; SPC2; neuroendocrine convertase 2; KEX2-like endoprotease 2; prohormone convertase 2

R&D Systems
sheep polyclonal
  • immunocytochemistry; human; 1:100; fig 2
In order to examine the osteoblast to osteocyte transition in regards to posttranslational processing, R&D Systems PC2 antibody (R&D Systems, AF6018) was used in immunocytochemistry on human samples at 1:100 (fig 2). Bone (2016) ncbi
Invitrogen
rabbit polyclonal
  • western blot; mouse; fig 4
  • western blot; human; fig 4
In order to identify alterations in the islet proteome that characterize the adaptive response, Invitrogen PC2 antibody (Thermo Fisher, PA1-058) was used in western blot on mouse samples (fig 4) and in western blot on human samples (fig 4). J Proteome Res (2015) ncbi
EMD Millipore
rabbit polyclonal
  • immunohistochemistry; mouse; fig s3
EMD Millipore PC2 antibody (EMD Millipore, AB15610) was used in immunohistochemistry on mouse samples (fig s3). Cell Metab (2014) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:200
EMD Millipore PC2 antibody (Millipore, ab15610) was used in immunohistochemistry - paraffin section on mouse samples at 1:200. PLoS ONE (2014) ncbi
Articles Reviewed
  1. Yamamoto H, Ramos Molina B, Lick A, Prideaux M, Albornoz V, Bonewald L, et al. Posttranslational processing of FGF23 in osteocytes during the osteoblast to osteocyte transition. Bone. 2016;84:120-130 pubmed publisher
  2. El Ouaamari A, Zhou J, Liew C, Shirakawa J, Dirice E, Gedeon N, et al. Compensatory Islet Response to Insulin Resistance Revealed by Quantitative Proteomics. J Proteome Res. 2015;14:3111-3122 pubmed publisher
  3. Kim Muller J, Zhao S, Srivastava S, Mugabo Y, Noh H, Kim Y, et al. Metabolic inflexibility impairs insulin secretion and results in MODY-like diabetes in triple FoxO-deficient mice. Cell Metab. 2014;20:593-602 pubmed publisher
  4. Moffett R, Vasu S, Thorens B, Drucker D, Flatt P. Incretin receptor null mice reveal key role of GLP-1 but not GIP in pancreatic beta cell adaptation to pregnancy. PLoS ONE. 2014;9:e96863 pubmed publisher