This is a Validated Antibody Database (VAD) review about human PALB2, based on 7 published articles (read how Labome selects the articles), using PALB2 antibody in all methods. It is aimed to help Labome visitors find the most suited PALB2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
PALB2 synonym: FANCN; PNCA3; partner and localizer of BRCA2; mutant partner and localizer of BRCA2

Bethyl
rabbit polyclonal
  • chromatin immunoprecipitation; human; fig 5a
  • western blot; human; 1:1000; loading ...; fig s1b
In order to research the protective effect of MRG15 and PALB2 from genotoxic stress, Bethyl PALB2 antibody (Bethyl, A301-246A) was used in chromatin immunoprecipitation on human samples (fig 5a) and in western blot on human samples at 1:1000 (fig s1b). Proc Natl Acad Sci U S A (2017) ncbi
rabbit polyclonal
  • EMSA; human; loading ...; fig 2
  • immunocytochemistry; human; loading ...; fig 3a
  • western blot; human; loading ...; fig 3c
Bethyl PALB2 antibody (Bethyl, A301-246A) was used in EMSA on human samples (fig 2), in immunocytochemistry on human samples (fig 3a) and in western blot on human samples (fig 3c). Nucleic Acids Res (2017) ncbi
rabbit polyclonal
  • immunoprecipitation; human; 1:5000; loading ...; fig 2e
  • western blot; human; 1:2500; loading ...; fig 2e
In order to describe a role for APRIN in homologous recombination, Bethyl PALB2 antibody (Bethyl, A301-246A) was used in immunoprecipitation on human samples at 1:5000 (fig 2e) and in western blot on human samples at 1:2500 (fig 2e). Nucleic Acids Res (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 6
Bethyl PALB2 antibody (Bethyl Laboratories, A301-247A) was used in western blot on human samples (fig 6). PLoS Genet (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 6
Bethyl PALB2 antibody (Bethyl Laboratories, A301-246A) was used in western blot on human samples (fig 6). PLoS Genet (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:2000; fig 3f
Bethyl PALB2 antibody (Bethyl Lab, A301-246) was used in western blot on human samples at 1:2000 (fig 3f). Nucleic Acids Res (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 2
Bethyl PALB2 antibody (Bethyl, A301-246A) was used in western blot on human samples (fig 2). Nucleic Acids Res (2015) ncbi
OriGene
rabbit polyclonal
  • immunoprecipitation; human
OriGene PALB2 antibody (Origene, TA306814) was used in immunoprecipitation on human samples . Hum Mol Genet (2015) ncbi
Articles Reviewed
  1. Bleuyard J, Fournier M, Nakato R, Couturier A, Katou Y, Ralf C, et al. MRG15-mediated tethering of PALB2 to unperturbed chromatin protects active genes from genotoxic stress. Proc Natl Acad Sci U S A. 2017;114:7671-7676 pubmed publisher
  2. Pauty J, Couturier A, Rodrigue A, Caron M, Coulombe Y, Dellaire G, et al. Cancer-causing mutations in the tumor suppressor PALB2 reveal a novel cancer mechanism using a hidden nuclear export signal in the WD40 repeat motif. Nucleic Acids Res. 2017;45:2644-2657 pubmed publisher
  3. Couturier A, Fleury H, Patenaude A, Bentley V, Rodrigue A, Coulombe Y, et al. Roles for APRIN (PDS5B) in homologous recombination and in ovarian cancer prediction. Nucleic Acids Res. 2016;44:10879-10897 pubmed
  4. Byrd P, Stewart G, Smith A, Eaton C, Taylor A, Guy C, et al. A Hypomorphic PALB2 Allele Gives Rise to an Unusual Form of FA-N Associated with Lymphoid Tumour Development. PLoS Genet. 2016;12:e1005945 pubmed publisher
  5. Parplys A, Zhao W, Sharma N, Groesser T, Liang F, Maranon D, et al. NUCKS1 is a novel RAD51AP1 paralog important for homologous recombination and genome stability. Nucleic Acids Res. 2015;43:9817-34 pubmed publisher
  6. Zuazua Villar P, Ganesh A, Phear G, Gagou M, Meuth M. Extensive RPA2 hyperphosphorylation promotes apoptosis in response to DNA replication stress in CHK1 inhibited cells. Nucleic Acids Res. 2015;43:9776-87 pubmed publisher
  7. Loke J, Pearlman A, Upadhyay K, Tesfa L, Shao Y, Ostrer H. Functional variant analyses (FVAs) predict pathogenicity in the BRCA1 DNA double-strand break repair pathway. Hum Mol Genet. 2015;24:3030-7 pubmed publisher