This is a Validated Antibody Database (VAD) review about human P cadherin, based on 31 published articles (read how Labome selects the articles), using P cadherin antibody in all methods. It is aimed to help Labome visitors find the most suited P cadherin antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
P cadherin synonym: CDHP; HJMD; PCAD

Invitrogen
mouse monoclonal (6A9)
  • western blot; mouse; 1:5000; fig 7
In order to assess the transiently formed junctional nexuses during post-natal mammary gland development by E-cadherins, connexins, beta-catenin, and claudin-7, Invitrogen P cadherin antibody (Thermo Scientific, MA1-2003) was used in western blot on mouse samples at 1:5000 (fig 7). Dev Biol (2016) ncbi
mouse monoclonal (12H6)
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; tbl 2
In order to characterize 21 cases of biphasic squamoid alveolar renal cell carcinoma, Invitrogen P cadherin antibody (Zymed, 12H6) was used in immunohistochemistry - paraffin section on human samples at 1:200 (tbl 2). Am J Surg Pathol (2016) ncbi
mouse monoclonal (12H6)
  • western blot; human; 1:1000
In order to develop and characterize a novel three-dimensional cell culture model of ovarian endometriosis, Invitrogen P cadherin antibody (Invitrogen, 12H6) was used in western blot on human samples at 1:1000. J Ovarian Res (2014) ncbi
mouse monoclonal (12H6)
  • western blot; human; fig 4
In order to compare the histological, biological, and molecular features of 2D and 3D epithelial ovarian cancer cultures, Invitrogen P cadherin antibody (Invitrogen, 32-4000) was used in western blot on human samples (fig 4). Lab Invest (2013) ncbi
mouse monoclonal (12H6)
  • immunocytochemistry; mouse; fig 1
  • western blot; mouse; fig 1
  • immunocytochemistry; human; fig 1
In order to elucidate alveolar rhabdomyosarcoma pathogenesis, Invitrogen P cadherin antibody (Invitrogen, 32-4000) was used in immunocytochemistry on mouse samples (fig 1), in western blot on mouse samples (fig 1) and in immunocytochemistry on human samples (fig 1). Oncogene (2013) ncbi
mouse monoclonal (12H6)
  • immunohistochemistry - paraffin section; human; 1:200; fig 7
In order to study the clinicopathologic features of 14 cases of sporadic hybrid oncocytic/chromophobe tumor of the kidney, Invitrogen P cadherin antibody (Zymed, 12H6) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig 7). Virchows Arch (2010) ncbi
mouse monoclonal (NCC-CAD-299)
  • blocking or activating experiments; human; fig 2b
In order to study the invasive behavior of P-cadherin expressing breast tumors, Invitrogen P cadherin antibody (Zymed Laboratories, NCC-CAD-299) was used in blocking or activating experiments on human samples (fig 2b). Oncogene (2010) ncbi
mouse monoclonal (NCC-CAD-299)
  • immunohistochemistry - paraffin section; human
  • immunoprecipitation; human
  • immunocytochemistry; human; 1:10
  • western blot; human
In order to measure the soluble fragment of P-cadherin in milk, nipple aspirate fluid, and plasma from breast cancer patients, Invitrogen P cadherin antibody (Zymed Laboratories, NCC-CAD-299) was used in immunohistochemistry - paraffin section on human samples , in immunoprecipitation on human samples , in immunocytochemistry on human samples at 1:10 and in western blot on human samples . Cancer Sci (2008) ncbi
mouse monoclonal (NCC-CAD-299)
  • blocking or activating experiments; human
In order to investigate the role of P-cadherin in bladder transitional cell carcinomas, Invitrogen P cadherin antibody (Zymed, 13-5800) was used in blocking or activating experiments on human samples . J Pathol (2008) ncbi
mouse monoclonal (12H6)
  • western blot; human; fig 6
In order to find that basic fibroblast growth factor downregulates typical cadherin expression on the surface of human umbilical vein endothelial cells via FGF receptor 1 signaling, Invitrogen P cadherin antibody (Zymed, 12H6) was used in western blot on human samples (fig 6). Exp Cell Res (2008) ncbi
mouse monoclonal (12H6)
  • western blot; human; 1:1000; fig 2
In order to assess if selective loss of progesterone receptor A or B affects the invasive capacity of endometrial cancer cells, Invitrogen P cadherin antibody (Zymed, 12H6) was used in western blot on human samples at 1:1000 (fig 2). J Soc Gynecol Investig (2005) ncbi
mouse monoclonal (NCC-CAD-299)
  • western blot; human
In order to investigate cisplatin-induced apoptosis in human embryo retinoblasts, Invitrogen P cadherin antibody (Zymed, NCC-CAD-299) was used in western blot on human samples . Cell Death Differ (1999) ncbi
R&D Systems
domestic goat polyclonal
  • immunohistochemistry; mouse; 1:300-1:600; loading ...; fig s7-1d
R&D Systems P cadherin antibody (R&D Systems, AF761) was used in immunohistochemistry on mouse samples at 1:300-1:600 (fig s7-1d). elife (2020) ncbi
mouse monoclonal (104805)
  • immunohistochemistry; human; 1:100; loading ...; fig 1e
R&D Systems P cadherin antibody (R&D Systems, MAB861) was used in immunohistochemistry on human samples at 1:100 (fig 1e). J Cell Biol (2020) ncbi
Abcam
mouse monoclonal (mAbcam22744)
  • western blot; human; 1:10,000; loading ...; fig 1c
  • western blot; mouse; 1:10,000; loading ...; fig s2b
Abcam P cadherin antibody (Abcam, AB22744) was used in western blot on human samples at 1:10,000 (fig 1c) and in western blot on mouse samples at 1:10,000 (fig s2b). Proc Natl Acad Sci U S A (2018) ncbi
mouse monoclonal (mAbcam22744)
  • immunocytochemistry; human; loading ...; fig s5d
In order to research the role of manganese efflux transporters in the maintenance of manganese homeostasis, Abcam P cadherin antibody (Abcam, ab22744) was used in immunocytochemistry on human samples (fig s5d). PLoS Genet (2017) ncbi
mouse monoclonal (mAbcam22744)
  • western blot; rat; loading ...; fig 3b
In order to ask if SK channels in the mitochondria inner membrane play an important role in regulating mitochondrial function in chronic cardiac diseases, Abcam P cadherin antibody (Abcam, ab22744) was used in western blot on rat samples (fig 3b). Cardiovasc Res (2017) ncbi
Santa Cruz Biotechnology
mouse monoclonal (CH-19)
  • western blot; mouse; loading ...; fig 4a
Santa Cruz Biotechnology P cadherin antibody (Santa Cruz, sc-59876) was used in western blot on mouse samples (fig 4a). J Clin Invest (2017) ncbi
mouse monoclonal (CH-19)
  • western blot; mouse; 1:4000; loading ...; fig 5c
Santa Cruz Biotechnology P cadherin antibody (Santa Cruz Biotechnology, sc-59876) was used in western blot on mouse samples at 1:4000 (fig 5c). Nat Neurosci (2014) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:200; loading ...; fig e9c
Cell Signaling Technology P cadherin antibody (Cell Signaling, 2130) was used in immunohistochemistry on mouse samples at 1:200 (fig e9c). Nature (2018) ncbi
domestic rabbit polyclonal
  • other; human; loading ...; fig 4c
Cell Signaling Technology P cadherin antibody (Cell Signaling, 2130) was used in other on human samples (fig 4c). Cancer Cell (2018) ncbi
domestic rabbit polyclonal
  • reverse phase protein lysate microarray; human; loading ...; fig st6
In order to characterize the molecular identity of uterine carcinosarcomas., Cell Signaling Technology P cadherin antibody (CST, 2130) was used in reverse phase protein lysate microarray on human samples (fig st6). Cancer Cell (2017) ncbi
domestic rabbit monoclonal (C13F9)
  • western blot; human; 1:1000; loading ...; fig 2a
In order to report how PTEN alters breast cancer metastatic behavior, Cell Signaling Technology P cadherin antibody (Cell Signaling, 2189) was used in western blot on human samples at 1:1000 (fig 2a). Anticancer Res (2016) ncbi
domestic rabbit monoclonal (C13F9)
  • western blot; human; 1:1000; fig 4
In order to characterize attenuation of triple negative breast cancer cells metastatic potential by the vitamin D analog, MART-10, Cell Signaling Technology P cadherin antibody (Cell Signaling Technology, 2189) was used in western blot on human samples at 1:1000 (fig 4). Int J Mol Sci (2016) ncbi
domestic rabbit monoclonal (C13F9)
  • western blot; human; 1:1000
In order to study the effect of epithelial cadherin expression on the induction of entosis, Cell Signaling Technology P cadherin antibody (Cell Signaling, 2189) was used in western blot on human samples at 1:1000. Cell Res (2014) ncbi
BD Biosciences
mouse monoclonal (56/P-Cadherin)
  • immunohistochemistry; human; 1:100; loading ...; fig 2b
BD Biosciences P cadherin antibody (BD Transduction Laboratories, 56) was used in immunohistochemistry on human samples at 1:100 (fig 2b). Mod Pathol (2020) ncbi
mouse monoclonal (56/P-Cadherin)
  • western blot; hamsters; loading ...; fig 6f
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 4c
  • western blot; mouse; loading ...; fig 5c
  • immunohistochemistry - paraffin section; human; loading ...; fig 7d
In order to describe how epithelial polarity proteins suppress malignant outgrowth, BD Biosciences P cadherin antibody (BD, 610228) was used in western blot on hamsters samples (fig 6f), in immunohistochemistry - paraffin section on mouse samples (fig 4c), in western blot on mouse samples (fig 5c) and in immunohistochemistry - paraffin section on human samples (fig 7d). J Exp Med (2017) ncbi
mouse monoclonal (56/P-Cadherin)
  • immunocytochemistry; human; fig 6
In order to analyze control of MT1-MMP endocytic and E-cadherin polarized golgi trafficking to promote invasive breast cancer programs by RAB2A, BD Biosciences P cadherin antibody (BD Transduction Laboratories, 610228) was used in immunocytochemistry on human samples (fig 6). EMBO Rep (2016) ncbi
mouse monoclonal (56/P-Cadherin)
  • immunohistochemistry - paraffin section; human; 1:400
In order to characterize aggressive tumors in African breast cancer and the strong expression of hypoxia-inducible factor-1 alpha (HIF-1alpha) and its association with Axl expression, BD Biosciences P cadherin antibody (BD Biosciences, 610227) was used in immunohistochemistry - paraffin section on human samples at 1:400. PLoS ONE (2016) ncbi
mouse monoclonal (56/P-Cadherin)
  • immunohistochemistry; human; loading ...; fig 2c
  • western blot; human; 1:1000; loading ...; fig 6b
BD Biosciences P cadherin antibody (BD Bioscience, 610227) was used in immunohistochemistry on human samples (fig 2c) and in western blot on human samples at 1:1000 (fig 6b). PLoS ONE (2015) ncbi
mouse monoclonal (56/P-Cadherin)
  • western blot; human; 1:500
BD Biosciences P cadherin antibody (BD Transduction Biosciences, 56) was used in western blot on human samples at 1:500. BMC Cancer (2014) ncbi
Articles Reviewed
  1. Xi L, Carroll T, Matos I, Luo J, Polak L, Pasolli H, et al. m6A RNA methylation impacts fate choices during skin morphogenesis. elife. 2020;9: pubmed publisher
  2. Christgen M, Bartels S, van Luttikhuizen J, Bublitz J, Rieger L, Christgen H, et al. E-cadherin to P-cadherin switching in lobular breast cancer with tubular elements. Mod Pathol. 2020;33:2483-2498 pubmed publisher
  3. Belote R, Simon S. Ca2+ transients in melanocyte dendrites and dendritic spine-like structures evoked by cell-to-cell signaling. J Cell Biol. 2020;219: pubmed publisher
  4. Seo B, Cho T, Lee D, Lee J, Lee B, Kim S, et al. LARGE, an intellectual disability-associated protein, regulates AMPA-type glutamate receptor trafficking and memory. Proc Natl Acad Sci U S A. 2018;115:7111-7116 pubmed publisher
  5. Liakath Ali K, Mills E, Sequeira I, Lichtenberger B, Pisco A, Sipilä K, et al. An evolutionarily conserved ribosome-rescue pathway maintains epidermal homeostasis. Nature. 2018;556:376-380 pubmed publisher
  6. Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  7. Rong X, Wang B, Palladino E, de Aguiar Vallim T, Ford D, Tontonoz P. ER phospholipid composition modulates lipogenesis during feeding and in obesity. J Clin Invest. 2017;127:3640-3651 pubmed publisher
  8. Xia Z, Wei J, Li Y, Wang J, Li W, Wang K, et al. Zebrafish slc30a10 deficiency revealed a novel compensatory mechanism of Atp2c1 in maintaining manganese homeostasis. PLoS Genet. 2017;13:e1006892 pubmed publisher
  9. Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed publisher
  10. Mescher M, Jeong P, Knapp S, Rübsam M, Saynisch M, Kranen M, et al. The epidermal polarity protein Par3 is a non-cell autonomous suppressor of malignant melanoma. J Exp Med. 2017;214:339-358 pubmed publisher
  11. Kim T, Terentyeva R, Roder K, Li W, Liu M, Greener I, et al. SK channel enhancers attenuate Ca2+-dependent arrhythmia in hypertrophic hearts by regulating mito-ROS-dependent oxidation and activity of RyR. Cardiovasc Res. 2017;113:343-353 pubmed publisher
  12. Chiang K, Hsu S, Lin S, Yeh C, Pang J, Wang S, et al. PTEN Insufficiency Increases Breast Cancer Cell Metastasis In Vitro and In Vivo in a Xenograft Zebrafish Model. Anticancer Res. 2016;36:3997-4005 pubmed
  13. Dianati E, Poiraud J, Weber Ouellette A, Plante I. Connexins, E-cadherin, Claudin-7 and ?-catenin transiently form junctional nexuses during the post-natal mammary gland development. Dev Biol. 2016;416:52-68 pubmed publisher
  14. Kajiho H, Kajiho Y, Frittoli E, Confalonieri S, Bertalot G, Viale G, et al. RAB2A controls MT1-MMP endocytic and E-cadherin polarized Golgi trafficking to promote invasive breast cancer programs. EMBO Rep. 2016;17:1061-80 pubmed publisher
  15. Chiang K, Yeh T, Chen S, Pang J, Yeh C, Hsu J, et al. The Vitamin D Analog, MART-10, Attenuates Triple Negative Breast Cancer Cells Metastatic Potential. Int J Mol Sci. 2016;17: pubmed publisher
  16. Hes O, Condom Mundo E, Peckova K, Lopez J, Martinek P, Vanecek T, et al. Biphasic Squamoid Alveolar Renal Cell Carcinoma: A Distinctive Subtype of Papillary Renal Cell Carcinoma?. Am J Surg Pathol. 2016;40:664-75 pubmed publisher
  17. Nalwoga H, Ahmed L, Arnes J, Wabinga H, Akslen L. Strong Expression of Hypoxia-Inducible Factor-1α (HIF-1α) Is Associated with Axl Expression and Features of Aggressive Tumors in African Breast Cancer. PLoS ONE. 2016;11:e0146823 pubmed publisher
  18. Lee Y, Han M, Baek S, Kim S, Oh S. MED30 Regulates the Proliferation and Motility of Gastric Cancer Cells. PLoS ONE. 2015;10:e0130826 pubmed publisher
  19. Lee Y, Ehninger D, Zhou M, Oh J, Kang M, Kwak C, et al. Mechanism and treatment for learning and memory deficits in mouse models of Noonan syndrome. Nat Neurosci. 2014;17:1736-43 pubmed publisher
  20. Sun Q, Cibas E, Huang H, Hodgson L, Overholtzer M. Induction of entosis by epithelial cadherin expression. Cell Res. 2014;24:1288-98 pubmed publisher
  21. Sousa B, Ribeiro A, Nobre A, Lopes N, Martins D, Pinheiro C, et al. The basal epithelial marker P-cadherin associates with breast cancer cell populations harboring a glycolytic and acid-resistant phenotype. BMC Cancer. 2014;14:734 pubmed publisher
  22. Brueggmann D, Templeman C, Starzinski Powitz A, Rao N, Gayther S, Lawrenson K. Novel three-dimensional in vitro models of ovarian endometriosis. J Ovarian Res. 2014;7:17 pubmed publisher
  23. Lee J, Mhawech Fauceglia P, Lee N, Parsanian L, Lin Y, Gayther S, et al. A three-dimensional microenvironment alters protein expression and chemosensitivity of epithelial ovarian cancer cells in vitro. Lab Invest. 2013;93:528-42 pubmed publisher
  24. Thuault S, Hayashi S, Lagirand Cantaloube J, Plutoni C, Comunale F, Delattre O, et al. P-cadherin is a direct PAX3-FOXO1A target involved in alveolar rhabdomyosarcoma aggressiveness. Oncogene. 2013;32:1876-87 pubmed publisher
  25. Petersson F, Gatalica Z, Grossmann P, Perez Montiel M, Alvarado Cabrero I, Bulimbasic S, et al. Sporadic hybrid oncocytic/chromophobe tumor of the kidney: a clinicopathologic, histomorphologic, immunohistochemical, ultrastructural, and molecular cytogenetic study of 14 cases. Virchows Arch. 2010;456:355-65 pubmed publisher
  26. Ribeiro A, Albergaria A, Sousa B, Correia A, Bracke M, Seruca R, et al. Extracellular cleavage and shedding of P-cadherin: a mechanism underlying the invasive behaviour of breast cancer cells. Oncogene. 2010;29:392-402 pubmed publisher
  27. Mannello F, Tonti G, Medda V, Pederzoli A, Sauter E. Increased shedding of soluble fragments of P-cadherin in nipple aspirate fluids from women with breast cancer. Cancer Sci. 2008;99:2160-9 pubmed publisher
  28. Bryan R, Atherfold P, Yeo Y, Jones L, Harrison R, Wallace D, et al. Cadherin switching dictates the biology of transitional cell carcinoma of the bladder: ex vivo and in vitro studies. J Pathol. 2008;215:184-94 pubmed publisher
  29. Wu J, Yan H, Chen W, Chen W, Wang C, Chi Y, et al. JNK signaling pathway is required for bFGF-mediated surface cadherin downregulation on HUVEC. Exp Cell Res. 2008;314:421-9 pubmed publisher
  30. Hanekamp E, Gielen S, De Ruiter P, Chadha Ajwani S, Huikeshoven F, Burger C, et al. Differences in invasive capacity of endometrial cancer cell lines expressing different progesterone receptor isotypes: possible involvement of cadherins. J Soc Gynecol Investig. 2005;12:278-84 pubmed
  31. Schmeiser K, Grand R. The fate of E- and P-cadherin during the early stages of apoptosis. Cell Death Differ. 1999;6:377-86 pubmed