This is a Validated Antibody Database (VAD) review about human OTX2, based on 7 published articles (read how Labome selects the articles), using OTX2 antibody in all methods. It is aimed to help Labome visitors find the most suited OTX2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
OTX2 synonym: CPHD6; MCOPS5

Knockout validation
R&D Systems
domestic goat polyclonal
  • immunohistochemistry knockout validation; mouse; loading ...; fig 1a
R&D Systems OTX2 antibody (R&D Systems, AF1979) was used in immunohistochemistry knockout validation on mouse samples (fig 1a). Eneuro (2021) ncbi
Santa Cruz Biotechnology
mouse monoclonal
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 2d
Santa Cruz Biotechnology OTX2 antibody (Santa Cruz, sc-514195) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 2d). Nat Commun (2020) ncbi
mouse monoclonal
  • western blot; human; loading ...; fig 1b
Santa Cruz Biotechnology OTX2 antibody (SantaCruz, sc-514195) was used in western blot on human samples (fig 1b). Cell Biol Int (2018) ncbi
R&D Systems
domestic goat polyclonal
  • immunohistochemistry knockout validation; mouse; loading ...; fig 1a
R&D Systems OTX2 antibody (R&D Systems, AF1979) was used in immunohistochemistry knockout validation on mouse samples (fig 1a). Eneuro (2021) ncbi
domestic goat polyclonal
  • immunohistochemistry - frozen section; chicken; 1:500; loading ...; fig 3a
R&D Systems OTX2 antibody (R&D, AF1979) was used in immunohistochemistry - frozen section on chicken samples at 1:500 (fig 3a). Sci Rep (2021) ncbi
domestic goat polyclonal
  • immunohistochemistry; mouse; 1:400; loading ...; fig 7h
R&D Systems OTX2 antibody (R&D, BAF1979) was used in immunohistochemistry on mouse samples at 1:400 (fig 7h). Front Cell Dev Biol (2021) ncbi
Invitrogen
mouse monoclonal (1H12C4B5)
  • immunohistochemistry; mouse; 1:200; loading ...; fig s4
Invitrogen OTX2 antibody (Thermo Fisher Scientific, #MA5-15854) was used in immunohistochemistry on mouse samples at 1:200 (fig s4). Proc Natl Acad Sci U S A (2020) ncbi
Abcam
domestic rabbit polyclonal
  • western blot; mouse; 1:500; fig 4b
Abcam OTX2 antibody (Abcam, ab114138) was used in western blot on mouse samples at 1:500 (fig 4b). BMC Biol (2016) ncbi
Articles Reviewed
  1. Pensieri P, Mantilleri A, Plassard D, Furukawa T, Moya K, Prochiantz A, et al. Photoreceptor cKO of OTX2 Enhances OTX2 Intercellular Transfer in the Retina and Causes Photophobia. Eneuro. 2021;8: pubmed publisher
  2. Chen X, Emerson M. Notch signaling represses cone photoreceptor formation through the regulation of retinal progenitor cell states. Sci Rep. 2021;11:14525 pubmed publisher
  3. Völkner M, Kurth T, Schor J, Ebner L, Bardtke L, Kavak C, et al. Mouse Retinal Organoid Growth and Maintenance in Longer-Term Culture. Front Cell Dev Biol. 2021;9:645704 pubmed publisher
  4. Ballabio C, Anderle M, Gianesello M, Lago C, Miele E, Cardano M, et al. Modeling medulloblastoma in vivo and with human cerebellar organoids. Nat Commun. 2020;11:583 pubmed publisher
  5. Su J, Charalambakis N, Sabbagh U, Somaiya R, Monavarfeshani A, Guido W, et al. Retinal inputs signal astrocytes to recruit interneurons into visual thalamus. Proc Natl Acad Sci U S A. 2020;117:2671-2682 pubmed publisher
  6. Fukuda T, Ishizawa Y, Donai K, Sugano E, Tomita H. The poly-cistronic expression of four transcriptional factors (CRX, RAX, NEURO-D, OTX2) in fibroblasts via retro- or lentivirus causes partial reprogramming into photoreceptor cells. Cell Biol Int. 2018;42:608-614 pubmed publisher
  7. Navarra A, Musto A, Gargiulo A, Petrosino G, Pierantoni G, Fusco A, et al. Hmga2 is necessary for Otx2-dependent exit of embryonic stem cells from the pluripotent ground state. BMC Biol. 2016;14:24 pubmed publisher