This is a Validated Antibody Database (VAD) review about human Nurr1, based on 10 published articles (read how Labome selects the articles), using Nurr1 antibody in all methods. It is aimed to help Labome visitors find the most suited Nurr1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Nurr1 synonym: HZF-3; NOT; NURR1; RNR1; TINUR

Knockout validation
R&D Systems
domestic goat polyclonal
  • immunohistochemistry knockout validation; mouse; 1:50; loading ...; fig 3
R&D Systems Nurr1 antibody (R&D Systems, AF2156) was used in immunohistochemistry knockout validation on mouse samples at 1:50 (fig 3). Front Neuroanat (2021) ncbi
Santa Cruz Biotechnology
mouse monoclonal (F-5)
  • flow cytometry; mouse; 1:50; loading ...; fig 11b
Santa Cruz Biotechnology Nurr1 antibody (Santa Cruz, SC-376984) was used in flow cytometry on mouse samples at 1:50 (fig 11b). iScience (2022) ncbi
mouse monoclonal (447C2a)
  • western blot; mouse; loading ...; fig 2o
Santa Cruz Biotechnology Nurr1 antibody (Santa Cruz Biotechnology, sc-81345) was used in western blot on mouse samples (fig 2o). J Cell Mol Med (2021) ncbi
mouse monoclonal (F-5)
  • flow cytometry; mouse; loading ...; fig ex4c
Santa Cruz Biotechnology Nurr1 antibody (Santa, sc-376984) was used in flow cytometry on mouse samples (fig ex4c). Nature (2019) ncbi
mouse monoclonal (447C2a)
  • western blot; rat; loading ...; fig 3a
Santa Cruz Biotechnology Nurr1 antibody (SantaCruz, 447C2a) was used in western blot on rat samples (fig 3a). Brain Res (2016) ncbi
mouse monoclonal (447C2a)
  • immunohistochemistry - paraffin section; human; loading ...; fig 1a
  • western blot; human; loading ...; fig 1d
Santa Cruz Biotechnology Nurr1 antibody (SantaCruz, sc-81345) was used in immunohistochemistry - paraffin section on human samples (fig 1a) and in western blot on human samples (fig 1d). Reprod Fertil Dev (2016) ncbi
Abcam
mouse monoclonal (N1404)
  • western blot; human; loading ...; fig 7a
Abcam Nurr1 antibody (Abcam, N1404) was used in western blot on human samples (fig 7a). Endocr Relat Cancer (2018) ncbi
mouse monoclonal (N1404)
  • flow cytometry; mouse; 1:75; fig 4d
In order to understand the role of prostaglandin E2 in skeletal muscle stem-cell function, Abcam Nurr1 antibody (Abcam, ab41917) was used in flow cytometry on mouse samples at 1:75 (fig 4d). Proc Natl Acad Sci U S A (2017) ncbi
R&D Systems
domestic goat polyclonal
  • immunohistochemistry knockout validation; mouse; 1:50; loading ...; fig 3
R&D Systems Nurr1 antibody (R&D Systems, AF2156) was used in immunohistochemistry knockout validation on mouse samples at 1:50 (fig 3). Front Neuroanat (2021) ncbi
MilliporeSigma
domestic rabbit polyclonal
  • immunohistochemistry; human; 1:500
MilliporeSigma Nurr1 antibody (Sigma-Aldrich, N4663) was used in immunohistochemistry on human samples at 1:500. Nat Commun (2021) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; mouse; 1:1000; loading ...; fig 5a
  • western blot; mouse; 1:1000; loading ...; fig 6a
In order to assess the differentiation potential of hippocampal neural stem cells, MilliporeSigma Nurr1 antibody (Sigma, N4663) was used in immunocytochemistry on mouse samples at 1:1000 (fig 5a) and in western blot on mouse samples at 1:1000 (fig 6a). Mol Med Rep (2016) ncbi
Articles Reviewed
  1. Turcato F, Wegman E, Lu T, Ferguson N, Luo Y. Dopaminergic neurons are not a major Sonic hedgehog ligand source for striatal cholinergic or PV interneurons. iScience. 2022;25:105278 pubmed publisher
  2. Teng Y, Liu Z, Chen X, Liu Y, Geng F, Le W, et al. Conditional deficiency of m6A methyltransferase Mettl14 in substantia nigra alters dopaminergic neuron function. J Cell Mol Med. 2021;25:8567-8572 pubmed publisher
  3. Kummari E, Guo Ross S, Partington H, Nutter J, Eells J. Quantitative Immunohistochemistry to Measure Regional Expression of Nurr1 in the Brain and the Effect of the Nurr1 Heterozygous Genotype. Front Neuroanat. 2021;15:563854 pubmed publisher
  4. Inak G, Rybak Wolf A, Lisowski P, Pentimalli T, Jüttner R, Glažar P, et al. Defective metabolic programming impairs early neuronal morphogenesis in neural cultures and an organoid model of Leigh syndrome. Nat Commun. 2021;12:1929 pubmed publisher
  5. Chen J, López Moyado I, Seo H, Lio C, Hempleman L, Sekiya T, et al. NR4A transcription factors limit CAR T cell function in solid tumours. Nature. 2019;567:530-534 pubmed publisher
  6. Wang Z, Wu D, Ng C, Teoh J, Yu S, Wang Y, et al. Nuclear receptor profiling in prostatospheroids and castration-resistant prostate cancer. Endocr Relat Cancer. 2018;25:35-50 pubmed publisher
  7. Ho A, Palla A, Blake M, Yucel N, Wang Y, Magnusson K, et al. Prostaglandin E2 is essential for efficacious skeletal muscle stem-cell function, augmenting regeneration and strength. Proc Natl Acad Sci U S A. 2017;114:6675-6684 pubmed publisher
  8. Arredondo C, Gonzalez M, Andrés M, Gysling K. Opposite effects of acute and chronic amphetamine on Nurr1 and NF-?B p65 in the rat ventral tegmental area. Brain Res. 2016;1652:14-20 pubmed publisher
  9. Ding Y, Zhang Z, Ma J, Xia H, Wang Y, Liu Y, et al. Directed differentiation of postnatal hippocampal neural stem cells generates nuclear receptor related?1 protein? and tyrosine hydroxylase?expressing cells. Mol Med Rep. 2016;14:1993-9 pubmed publisher
  10. Lappas M. Effect of spontaneous term labour on the expression of the NR4A receptors nuclear receptor related 1 protein (Nurr1), neuron-derived clone 77 (Nur77) and neuron-derived orphan receptor 1 (NOR1) in human fetal membranes and myometrium. Reprod Fertil Dev. 2016;28:893-906 pubmed publisher