This is a Validated Antibody Database (VAD) review about human Nedd8, based on 11 published articles (read how Labome selects the articles), using Nedd8 antibody in all methods. It is aimed to help Labome visitors find the most suited Nedd8 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Nedd8 synonym: NEDD-8; NEDD8; neddylin; ubiquitin-like protein Nedd8

Invitrogen
rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...
In order to test if increased NUB1 protein levels reduces mutant huntingtin levels through a proteasome dependent mechanism, Invitrogen Nedd8 antibody (Pierce, PA5-17476) was used in western blot on mouse samples at 1:1000. J Huntingtons Dis (2016) ncbi
rabbit polyclonal
  • western blot; human
In order to study the effect of neddylation on COP9-Signalosome deneddylase activity, Invitrogen Nedd8 antibody (Invitrogen, 34-1400) was used in western blot on human samples . Cell Div (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 4
In order to elucidate how cycle inhibiting factor modulates NEDD8-dependent signaling, Invitrogen Nedd8 antibody (Invitrogen, 34-1400) was used in western blot on human samples (fig 4). J Biol Chem (2013) ncbi
rabbit polyclonal
  • western blot; human; fig 1
In order to elucidate resistance to MLN4924, Invitrogen Nedd8 antibody (Invitrogen, 34-1400) was used in western blot on human samples (fig 1). Cell Rep (2012) ncbi
rabbit polyclonal
  • western blot; human; fig 5
In order to generate a protein microarray-based assay to measure post-translational modifications, Invitrogen Nedd8 antibody (Zymed, 34-1400) was used in western blot on human samples (fig 5). PLoS ONE (2010) ncbi
Abcam
rabbit monoclonal (Y297)
  • western blot; human; fig s9
In order to analyze tamoxifen-resistance in ERalpha-positive breast cancer by degradation of NCoR due to COPS5 amplification and overexpression, Abcam Nedd8 antibody (Abcam, ab81264) was used in western blot on human samples (fig s9). Nat Commun (2016) ncbi
Cell Signaling Technology
rabbit monoclonal (19E3)
  • western blot; human; loading ...; fig 4b
Cell Signaling Technology Nedd8 antibody (Cell Signaling, 2754) was used in western blot on human samples (fig 4b). Nat Struct Mol Biol (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 1
Cell Signaling Technology Nedd8 antibody (Cell signaling, 2745) was used in western blot on human samples (fig 1). J Virol (2016) ncbi
rabbit monoclonal (19E3)
  • western blot; mouse; 1:150; fig 3
Cell Signaling Technology Nedd8 antibody (Cell Signaling, 2754) was used in western blot on mouse samples at 1:150 (fig 3). Dis Model Mech (2015) ncbi
rabbit monoclonal (19E3)
  • western blot; human; fig 6
Cell Signaling Technology Nedd8 antibody (Cell Signaling Technology, 2754) was used in western blot on human samples (fig 6). Oncotarget (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 6
Cell Signaling Technology Nedd8 antibody (Cell Signaling Technology, 2745) was used in western blot on human samples (fig 6). Oncotarget (2015) ncbi
rabbit monoclonal (19E3)
  • western blot; human; fig 2
Cell Signaling Technology Nedd8 antibody (Cell Signaling Technology, 19E3) was used in western blot on human samples (fig 2). J Biol Chem (2015) ncbi
Articles Reviewed
  1. Lu R, Hu X, Zhou J, Sun J, Zhu A, Xu X, et al. COPS5 amplification and overexpression confers tamoxifen-resistance in ER?-positive breast cancer by degradation of NCoR. Nat Commun. 2016;7:12044 pubmed publisher
  2. Mo Z, Zhang Q, Liu Z, Lauer J, Shi Y, Sun L, et al. Neddylation requires glycyl-tRNA synthetase to protect activated E2. Nat Struct Mol Biol. 2016;23:730-7 pubmed publisher
  3. Vodicka P, Chase K, Iuliano M, Valentine D, Sapp E, Lu B, et al. Effects of Exogenous NUB1 Expression in the Striatum of HDQ175/Q7 Mice. J Huntingtons Dis. 2016;5:163-74 pubmed publisher
  4. Gilson T, Blanchette P, Ballmann M, Papp T, Pénzes J, Benkő M, et al. Using the E4orf6-Based E3 Ubiquitin Ligase as a Tool To Analyze the Evolution of Adenoviruses. J Virol. 2016;90:7350-7367 pubmed publisher
  5. Tateossian H, Morse S, Simon M, Dean C, Brown S. Interactions between the otitis media gene, Fbxo11, and p53 in the mouse embryonic lung. Dis Model Mech. 2015;8:1531-42 pubmed publisher
  6. Bornstein G, Grossman C. COP9-Signalosome deneddylase activity is enhanced by simultaneous neddylation: insights into the regulation of an enzymatic protein complex. Cell Div. 2015;10:5 pubmed publisher
  7. Pulvino M, Chen L, Oleksyn D, Li J, Compitello G, Rossi R, et al. Inhibition of COP9-signalosome (CSN) deneddylating activity and tumor growth of diffuse large B-cell lymphomas by doxycycline. Oncotarget. 2015;6:14796-813 pubmed
  8. Ibeawuchi S, Agbor L, Quelle F, Sigmund C. Hypertension-causing Mutations in Cullin3 Protein Impair RhoA Protein Ubiquitination and Augment the Association with Substrate Adaptors. J Biol Chem. 2015;290:19208-17 pubmed publisher
  9. Toro T, Toth J, Petroski M. The cyclomodulin cycle inhibiting factor (CIF) alters cullin neddylation dynamics. J Biol Chem. 2013;288:14716-26 pubmed publisher
  10. Toth J, Yang L, Dahl R, Petroski M. A gatekeeper residue for NEDD8-activating enzyme inhibition by MLN4924. Cell Rep. 2012;1:309-16 pubmed publisher
  11. Del Rincón S, Rogers J, Widschwendter M, Sun D, Sieburg H, Spruck C. Development and validation of a method for profiling post-translational modification activities using protein microarrays. PLoS ONE. 2010;5:e11332 pubmed publisher