This is a Validated Antibody Database (VAD) review about human NSD2, based on 8 published articles (read how Labome selects the articles), using NSD2 antibody in all methods. It is aimed to help Labome visitors find the most suited NSD2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
NSD2 synonym: KMT3F; KMT3G; MMSET; REIIBP; TRX5; WHS; WHSC1

Abcam
mouse monoclonal (29D1)
  • immunohistochemistry - paraffin section; human; loading ...; fig 2e, 7f
  • immunoprecipitation; human; loading ...; fig 3d
  • western blot; human; loading ...; fig 2a, 2b
Abcam NSD2 antibody (Abcam, ab75359) was used in immunohistochemistry - paraffin section on human samples (fig 2e, 7f), in immunoprecipitation on human samples (fig 3d) and in western blot on human samples (fig 2a, 2b). Clin Transl Med (2022) ncbi
mouse monoclonal (29D1)
  • immunohistochemistry; mouse; loading ...
  • chromatin immunoprecipitation; human; loading ...; fig 7h
  • immunohistochemistry; human; loading ...; fig 5l
In order to demonstrate that WHSC1 drives indolent PTEN-null tumors to become metastatic prostate cancer, Abcam NSD2 antibody (Abcam, ab75359) was used in immunohistochemistry on mouse samples , in chromatin immunoprecipitation on human samples (fig 7h) and in immunohistochemistry on human samples (fig 5l). J Clin Invest (2017) ncbi
mouse monoclonal (29D1)
  • western blot; human; loading ...
Abcam NSD2 antibody (Abcam, ab75359) was used in western blot on human samples . Science (2016) ncbi
mouse monoclonal (29D1)
  • western blot; human; fig 1
Abcam NSD2 antibody (Abcam, ab75359) was used in western blot on human samples (fig 1). Mol Cancer Ther (2016) ncbi
mouse monoclonal (29D1)
  • immunohistochemistry - paraffin section; human; 1:400
  • western blot; human
Abcam NSD2 antibody (Abcam, ab75359) was used in immunohistochemistry - paraffin section on human samples at 1:400 and in western blot on human samples . Mol Cancer Res (2015) ncbi
mouse monoclonal (29D1)
  • immunoprecipitation; human
  • western blot; human
Abcam NSD2 antibody (Abcam, ab75359) was used in immunoprecipitation on human samples and in western blot on human samples . Cell Res (2014) ncbi
mouse monoclonal (29D1)
  • chromatin immunoprecipitation; mouse
Abcam NSD2 antibody (Abcam, ab75359) was used in chromatin immunoprecipitation on mouse samples . J Immunol (2013) ncbi
Active Motif
mouse monoclonal (29D1)
  • western blot; human; fig 3
Active Motif NSD2 antibody (Active Motif, 39879) was used in western blot on human samples (fig 3). Sci Rep (2016) ncbi
Articles Reviewed
  1. Jiang H, Wang Y, Wang J, Wang Y, Wang S, He E, et al. Posttranslational modification of Aurora A-NSD2 loop contributes to drug resistance in t(4;14) multiple myeloma. Clin Transl Med. 2022;12:e744 pubmed publisher
  2. Li N, Xue W, Yuan H, Dong B, Ding Y, Liu Y, et al. AKT-mediated stabilization of histone methyltransferase WHSC1 promotes prostate cancer metastasis. J Clin Invest. 2017;127:1284-1302 pubmed publisher
  3. García Carpizo V, Sarmentero J, Han B, Grana O, Ruiz Llorente S, Pisano D, et al. NSD2 contributes to oncogenic RAS-driven transcription in lung cancer cells through long-range epigenetic activation. Sci Rep. 2016;6:32952 pubmed publisher
  4. Fang D, Gan H, Lee J, Han J, Wang Z, Riester S, et al. The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas. Science. 2016;352:1344-8 pubmed publisher
  5. Hernando H, Gelato K, Lesche R, Beckmann G, Koehr S, Otto S, et al. EZH2 Inhibition Blocks Multiple Myeloma Cell Growth through Upregulation of Epithelial Tumor Suppressor Genes. Mol Cancer Ther. 2016;15:287-98 pubmed publisher
  6. Saloura V, Cho H, Kiyotani K, Alachkar H, Zuo Z, Nakakido M, et al. WHSC1 promotes oncogenesis through regulation of NIMA-related kinase-7 in squamous cell carcinoma of the head and neck. Mol Cancer Res. 2015;13:293-304 pubmed publisher
  7. Feng Q, Zhang Z, Shea M, Creighton C, Coarfa C, Hilsenbeck S, et al. An epigenomic approach to therapy for tamoxifen-resistant breast cancer. Cell Res. 2014;24:809-19 pubmed publisher
  8. Pei H, Wu X, Liu T, Yu K, Jelinek D, Lou Z. The histone methyltransferase MMSET regulates class switch recombination. J Immunol. 2013;190:756-63 pubmed publisher