This is a Validated Antibody Database (VAD) review about human NRP2, based on 12 published articles (read how Labome selects the articles), using NRP2 antibody in all methods. It is aimed to help Labome visitors find the most suited NRP2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
NRP2 synonym: NP2; NPN2; PRO2714; VEGF165R2

Knockout validation
Cell Signaling Technology
domestic rabbit monoclonal (D39A5)
  • western blot knockout validation; human; loading ...; fig 4g
  • western blot knockout validation; mouse; loading ...; fig 4c
Cell Signaling Technology NRP2 antibody (CST, D39A5) was used in western blot knockout validation on human samples (fig 4g) and in western blot knockout validation on mouse samples (fig 4c). Bone Res (2021) ncbi
Santa Cruz Biotechnology
mouse monoclonal (C-9)
  • western blot; human; fig 6b
Santa Cruz Biotechnology NRP2 antibody (SantaCruz, sc13117) was used in western blot on human samples (fig 6b). Cancer Cell (2017) ncbi
mouse monoclonal (C-9)
  • immunohistochemistry; rat; 1:50; fig 2
  • western blot; rat; fig 6
Santa Cruz Biotechnology NRP2 antibody (Santa Cruz biotechnology, sc-13117) was used in immunohistochemistry on rat samples at 1:50 (fig 2) and in western blot on rat samples (fig 6). Cardiovasc Res (2015) ncbi
mouse monoclonal (C-9)
  • immunocytochemistry; human; fig 2
  • western blot; human; fig 1
Santa Cruz Biotechnology NRP2 antibody (Santa Cruz Biotechnology, sc-13117) was used in immunocytochemistry on human samples (fig 2) and in western blot on human samples (fig 1). Mol Cancer (2015) ncbi
mouse monoclonal (C-9)
  • western blot; human
Santa Cruz Biotechnology NRP2 antibody (Santa Cruz Biotechnology, sc-13117) was used in western blot on human samples . J Neurooncol (2014) ncbi
R&D Systems
domestic goat polyclonal
  • immunohistochemistry; mouse; 1:200; loading ...; fig 3e
R&D Systems NRP2 antibody (R&D, AF2215) was used in immunohistochemistry on mouse samples at 1:200 (fig 3e). Sci Adv (2021) ncbi
Abcam
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; fig s5n
Abcam NRP2 antibody (Abcam, ab234821) was used in immunohistochemistry - paraffin section on human samples (fig s5n). J Clin Invest (2022) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D39A5)
  • immunohistochemistry - frozen section; mouse; 1:50; loading ...; fig 1b
Cell Signaling Technology NRP2 antibody (Cell Signaling, D39A5) was used in immunohistochemistry - frozen section on mouse samples at 1:50 (fig 1b). Front Genet (2021) ncbi
domestic rabbit monoclonal (D39A5)
  • immunohistochemistry; mouse; 1:500; loading ...; fig 5a
Cell Signaling Technology NRP2 antibody (Cell Signaling Technology, 3366) was used in immunohistochemistry on mouse samples at 1:500 (fig 5a). Nat Commun (2021) ncbi
domestic rabbit monoclonal (D39A5)
  • western blot knockout validation; human; loading ...; fig 4g
  • western blot knockout validation; mouse; loading ...; fig 4c
Cell Signaling Technology NRP2 antibody (CST, D39A5) was used in western blot knockout validation on human samples (fig 4g) and in western blot knockout validation on mouse samples (fig 4c). Bone Res (2021) ncbi
domestic rabbit monoclonal (D39A5)
  • immunohistochemistry; mouse; 1:500; fig 1
In order to analyze secreted semaphorin sink to facilitate commissural axon midline crossing by floor plate-derived neuropilin-2, Cell Signaling Technology NRP2 antibody (Cell Signaling Technology, D39A5) was used in immunohistochemistry on mouse samples at 1:500 (fig 1). Genes Dev (2015) ncbi
domestic rabbit monoclonal (D39A5)
  • immunocytochemistry; mouse; fig s4
  • immunohistochemistry; mouse; loading ...; fig 1d
In order to study the polysialylation of CCR7, Cell Signaling Technology NRP2 antibody (cell signalling, D29A5) was used in immunocytochemistry on mouse samples (fig s4) and in immunohistochemistry on mouse samples (fig 1d). Science (2016) ncbi
domestic rabbit monoclonal (D39A5)
  • western blot; rat
Cell Signaling Technology NRP2 antibody (Cell signalling technology, 3366) was used in western blot on rat samples . Cardiovasc Res (2015) ncbi
domestic rabbit monoclonal (D39A5)
  • western blot; mouse; fig 4
In order to study Shh signaling during oncogenesis and hindbrain development due to Eya1 phosphate promotion, Cell Signaling Technology NRP2 antibody (Cell Signaling, 3366) was used in western blot on mouse samples (fig 4). Dev Cell (2015) ncbi
Articles Reviewed
  1. Luo Y, Li Z, Kong Y, He W, Zheng H, An M, et al. KRAS mutant-driven SUMOylation controls extracellular vesicle transmission to trigger lymphangiogenesis in pancreatic cancer. J Clin Invest. 2022;132: pubmed publisher
  2. Kalisch Smith J, Morris E, Strevens M, Redpath A, Klaourakis K, Szumska D, et al. Analysis of Placental Arteriovenous Formation Reveals New Insights Into Embryos With Congenital Heart Defects. Front Genet. 2021;12:806136 pubmed publisher
  3. Aoki M, Gamayun I, Wyatt A, Grünewald R, Simon Thomas M, Philipp S, et al. Prolactin-sensitive olfactory sensory neurons regulate male preference in female mice by modulating responses to chemosensory cues. Sci Adv. 2021;7:eabg4074 pubmed publisher
  4. Kalisch Smith J, Ved N, Szumska D, Munro J, Troup M, Harris S, et al. Maternal iron deficiency perturbs embryonic cardiovascular development in mice. Nat Commun. 2021;12:3447 pubmed publisher
  5. Polavaram N, Dutta S, Islam R, Bag A, Roy S, Poitz D, et al. Tumor- and osteoclast-derived NRP2 in prostate cancer bone metastases. Bone Res. 2021;9:24 pubmed publisher
  6. Agrawal P, Fontanals Cirera B, Sokolova E, Jacob S, Vaiana C, Argibay D, et al. A Systems Biology Approach Identifies FUT8 as a Driver of Melanoma Metastasis. Cancer Cell. 2017;31:804-819.e7 pubmed publisher
  7. Hernández Enríquez B, Wu Z, Martinez E, Olsen O, Kaprielian Z, Maness P, et al. Floor plate-derived neuropilin-2 functions as a secreted semaphorin sink to facilitate commissural axon midline crossing. Genes Dev. 2015;29:2617-32 pubmed publisher
  8. Kiermaier E, Moussion C, Veldkamp C, Gerardy Schahn R, de Vries I, Williams L, et al. Polysialylation controls dendritic cell trafficking by regulating chemokine recognition. Science. 2016;351:186-90 pubmed publisher
  9. Pellet Many C, Mehta V, Fields L, Mahmoud M, Lowe V, Evans I, et al. Neuropilins 1 and 2 mediate neointimal hyperplasia and re-endothelialization following arterial injury. Cardiovasc Res. 2015;108:288-98 pubmed publisher
  10. Ji T, Guo Y, Kim K, McQueen P, Ghaffar S, Christ A, et al. Neuropilin-2 expression is inhibited by secreted Wnt antagonists and its down-regulation is associated with reduced tumor growth and metastasis in osteosarcoma. Mol Cancer. 2015;14:86 pubmed publisher
  11. Eisner A, Pazyra Murphy M, Durresi E, Zhou P, Zhao X, Chadwick E, et al. The Eya1 phosphatase promotes Shh signaling during hindbrain development and oncogenesis. Dev Cell. 2015;33:22-35 pubmed publisher
  12. Epis M, Giles K, Candy P, Webster R, Leedman P. miR-331-3p regulates expression of neuropilin-2 in glioblastoma. J Neurooncol. 2014;116:67-75 pubmed publisher