This is a Validated Antibody Database (VAD) review about human NRG1, based on 7 published articles (read how Labome selects the articles), using NRG1 antibody in all methods. It is aimed to help Labome visitors find the most suited NRG1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
NRG1 synonym: ARIA; GGF; GGF2; HGL; HRG; HRG1; HRGA; MST131; MSTP131; NDF; NRG1-IT2; SMDF; pro-neuregulin-1, membrane-bound isoform; acetylcholine receptor-inducing activity; glial growth factor 2; heregulin, alpha (45kD, ERBB2 p185-activator); neu differentiation factor; pro-NRG1; sensory and motor neuron derived factor

R&D Systems
goat polyclonal
  • ELISA; human; fig 2b
In order to determine how hepatitis C virus activates a neuregulin-driven circuit to modify surface expression of growth factor receptors of the ErbB family, R&D Systems NRG1 antibody (R&D Systems, AF-396-NA) was used in ELISA on human samples (fig 2b). PLoS ONE (2016) ncbi
goat polyclonal
  • western blot; human; 1:500
R&D Systems NRG1 antibody (R&D, AF2015) was used in western blot on human samples at 1:500. Oncotarget (2014) ncbi
Invitrogen
mouse monoclonal (7D5)
  • western blot; mouse; 1:500; fig 2
In order to study the alterations of brain Neuregulin-1 signaling during neuroinflammation, Invitrogen NRG1 antibody (LabVision; Thermo Fisher Scientific, MS-272-P1) was used in western blot on mouse samples at 1:500 (fig 2). Mol Med Rep (2016) ncbi
Abcam
rabbit polyclonal
  • western blot; mouse; loading ...; fig 3f
In order to investigate the reemergence of hippocampal long-term potential in a mouse model of Alzheimer's disease, Abcam NRG1 antibody (Abcam, ab53104) was used in western blot on mouse samples (fig 3f). Sci Rep (2016) ncbi
Cell Signaling Technology
rabbit polyclonal
  • other; human; loading ...; fig 4c
Cell Signaling Technology NRG1 antibody (Cell Signaling, 2573) was used in other on human samples (fig 4c). Cancer Cell (2018) ncbi
rabbit polyclonal
  • reverse phase protein lysate microarray; human; loading ...; fig st6
In order to characterize the molecular identity of uterine carcinosarcomas., Cell Signaling Technology NRG1 antibody (CST, 2573) was used in reverse phase protein lysate microarray on human samples (fig st6). Cancer Cell (2017) ncbi
rabbit polyclonal
  • western blot; human; fig 1b
Cell Signaling Technology NRG1 antibody (Cell signaling, 2573) was used in western blot on human samples (fig 1b). J Biol Chem (2015) ncbi
Articles Reviewed
  1. Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  2. Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed publisher
  3. Huh S, Baek S, Lee K, Whitcomb D, Jo J, Choi S, et al. The reemergence of long-term potentiation in aged Alzheimer's disease mouse model. Sci Rep. 2016;6:29152 pubmed publisher
  4. Yang Z, Jiang Q, Chen S, Hu C, Shen H, Huang P, et al. Differential changes in Neuregulin-1 signaling in major brain regions in a lipopolysaccharide-induced neuroinflammation mouse model. Mol Med Rep. 2016;14:790-6 pubmed publisher
  5. Stindt S, Cebula P, Albrecht U, Keitel V, Schulte Am Esch J, Knoefel W, et al. Hepatitis C Virus Activates a Neuregulin-Driven Circuit to Modify Surface Expression of Growth Factor Receptors of the ErbB Family. PLoS ONE. 2016;11:e0148711 pubmed publisher
  6. Capparelli C, Rosenbaum S, Berger A, Aplin A. Fibroblast-derived neuregulin 1 promotes compensatory ErbB3 receptor signaling in mutant BRAF melanoma. J Biol Chem. 2015;290:24267-77 pubmed publisher
  7. Pajtler K, Mahlow E, Odersky A, Lindner S, Stephan H, Bendix I, et al. Neuroblastoma in dialog with its stroma: NTRK1 is a regulator of cellular cross-talk with Schwann cells. Oncotarget. 2014;5:11180-92 pubmed