This is a Validated Antibody Database (VAD) review about human NRBF 2, based on 2 published articles (read how Labome selects the articles), using NRBF 2 antibody in all methods. It is aimed to help Labome visitors find the most suited NRBF 2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
NRBF 2 synonym: COPR; COPR1; COPR2; NRBF-2; nuclear receptor-binding factor 2; comodulator of PPAR and RXR 1; comodulator of PPAR and RXR 2

Knockout validation
Cell Signaling Technology
rabbit monoclonal (D8G1)
  • western blot knockout validation; mouse; 1:500; fig s1
In order to identify mechanisms that control of PI3K-III activity, Cell Signaling Technology NRBF 2 antibody (Cell Signaling Technology, 8633) was used in western blot knockout validation on mouse samples at 1:500 (fig s1). Nat Commun (2014) ncbi
Bethyl
rabbit polyclonal
  • western blot; human; 1:5000
In order to identify and characterize the Nrbf2-Beclin 1 interaction, Bethyl NRBF 2 antibody (Bethyl, A301-852A) was used in western blot on human samples at 1:5000. J Biol Chem (2014) ncbi
rabbit polyclonal
  • immunoprecipitation; mouse; 1:100
In order to identify mechanisms that control of PI3K-III activity, Bethyl NRBF 2 antibody (Bethyl, A301-852A) was used in immunoprecipitation on mouse samples at 1:100. Nat Commun (2014) ncbi
Cell Signaling Technology
rabbit monoclonal (D8G1)
  • western blot knockout validation; mouse; 1:500; fig s1
In order to identify mechanisms that control of PI3K-III activity, Cell Signaling Technology NRBF 2 antibody (Cell Signaling Technology, 8633) was used in western blot knockout validation on mouse samples at 1:500 (fig s1). Nat Commun (2014) ncbi
Articles Reviewed
  1. Zhong Y, Morris D, Jin L, Patel M, Karunakaran S, Fu Y, et al. Nrbf2 protein suppresses autophagy by modulating Atg14L protein-containing Beclin 1-Vps34 complex architecture and reducing intracellular phosphatidylinositol-3 phosphate levels. J Biol Chem. 2014;289:26021-37 pubmed publisher
  2. Lu J, He L, Behrends C, Araki M, Araki K, Jun Wang Q, et al. NRBF2 regulates autophagy and prevents liver injury by modulating Atg14L-linked phosphatidylinositol-3 kinase III activity. Nat Commun. 2014;5:3920 pubmed publisher