This is a Validated Antibody Database (VAD) review about human NR1H4, based on 5 published articles (read how Labome selects the articles), using NR1H4 antibody in all methods. It is aimed to help Labome visitors find the most suited NR1H4 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
NR1H4 synonym: BAR; FXR; HRR-1; HRR1; PFIC5; RIP14

Knockout validation
Invitrogen
mouse monoclonal (A9033A)
  • western blot knockout validation; mouse; loading ...; fig s1
Invitrogen NR1H4 antibody (Invitrogen, A9033A) was used in western blot knockout validation on mouse samples (fig s1). JHEP Rep (2021) ncbi
R&D Systems
mouse monoclonal (A9033A)
  • immunohistochemistry - paraffin section; human; loading ...; fig s4b
R&D Systems NR1H4 antibody (R&D, PP-A9033A-00) was used in immunohistochemistry - paraffin section on human samples (fig s4b). J Biol Chem (2022) ncbi
mouse monoclonal (A9033A)
  • immunohistochemistry - paraffin section; human; 1:300; fig 1e
R&D Systems NR1H4 antibody (R&D Systems, PP-A9033A-00) was used in immunohistochemistry - paraffin section on human samples at 1:300 (fig 1e). Virchows Arch (2021) ncbi
Invitrogen
mouse monoclonal (A9033A)
  • western blot knockout validation; mouse; loading ...; fig s1
Invitrogen NR1H4 antibody (Invitrogen, A9033A) was used in western blot knockout validation on mouse samples (fig s1). JHEP Rep (2021) ncbi
mouse monoclonal (A9033A)
  • immunocytochemistry; rat
  • western blot; rat
In order to study the effect of bile acids on mesenchymal stem cells in liver, Invitrogen NR1H4 antibody (Invitrogen, 417200) was used in immunocytochemistry on rat samples and in western blot on rat samples . Sci Rep (2015) ncbi
Santa Cruz Biotechnology
mouse monoclonal (D-3)
  • immunohistochemistry - paraffin section; human; loading ...; fig 2a
  • immunocytochemistry; human; 1:100; loading ...; fig 4b
  • western blot; human; loading ...; fig 1c
Santa Cruz Biotechnology NR1H4 antibody (Santa Cruz, sc-25309) was used in immunohistochemistry - paraffin section on human samples (fig 2a), in immunocytochemistry on human samples at 1:100 (fig 4b) and in western blot on human samples (fig 1c). Cell Death Dis (2022) ncbi
Articles Reviewed
  1. Wang X, Xie C, Libby A, Ranjit S, Levi J, Myakala K, et al. The role of FXR and TGR5 in reversing and preventing progression of Western diet-induced hepatic steatosis, inflammation, and fibrosis in mice. J Biol Chem. 2022;298:102530 pubmed publisher
  2. Yu J, Yang K, Zheng J, Zhao P, Xia J, Sun X, et al. Activation of FXR and inhibition of EZH2 synergistically inhibit colorectal cancer through cooperatively accelerating FXR nuclear location and upregulating CDX2 expression. Cell Death Dis. 2022;13:388 pubmed publisher
  3. Ijssennagger N, van Rooijen K, Magnúsdóttir S, Ramos Pittol J, Willemsen E, de Zoete M, et al. Ablation of liver Fxr results in an increased colonic mucus barrier in mice. JHEP Rep. 2021;3:100344 pubmed publisher
  4. Nortunen M, V xe4 kiparta N, Porvari K, Saarnio J, Karttunen T, Huhta H. Pathophysiology of reflux oesophagitis: role of Toll-like receptors 2 and 4 and Farnesoid X receptor. Virchows Arch. 2021;479:285-293 pubmed publisher
  5. Sawitza I, Kordes C, Götze S, Herebian D, Häussinger D. Bile acids induce hepatic differentiation of mesenchymal stem cells. Sci Rep. 2015;5:13320 pubmed publisher