This is a Validated Antibody Database (VAD) review about human NR1D1, based on 8 published articles (read how Labome selects the articles), using NR1D1 antibody in all methods. It is aimed to help Labome visitors find the most suited NR1D1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
NR1D1 synonym: EAR1; REVERBA; REVERBalpha; THRA1; THRAL; ear-1; hRev; nuclear receptor subfamily 1 group D member 1; Rev-ErbAalpha; V-erbA-related protein 1; nuclear receptor Rev-ErbA-alpha; rev-erbA-alpha

Knockout validation
Santa Cruz Biotechnology
mouse monoclonal (RS-14)
  • immunohistochemistry knockout validation; mouse; loading ...; fig 3
  • western blot knockout validation; mouse; 1:200; loading ...; fig 2c
Santa Cruz Biotechnology NR1D1 antibody (Santa Cruz, sc-100910) was used in immunohistochemistry knockout validation on mouse samples (fig 3) and in western blot knockout validation on mouse samples at 1:200 (fig 2c). J Cell Sci (2016) ncbi
Abcam
rabbit monoclonal (EPR10376)
  • immunohistochemistry; mouse; loading ...; fig 1c
  • immunohistochemistry; human; loading ...; fig 1b
In order to study circadian rhythmicity in cultured chondrocytes and determine the role of NR1D1 and BMAL1 in regulating chondrocyte functions, Abcam NR1D1 antibody (Abcam, ab174309) was used in immunohistochemistry on mouse samples (fig 1c) and in immunohistochemistry on human samples (fig 1b). Osteoarthritis Cartilage (2017) ncbi
rabbit monoclonal (EPR10376)
  • immunohistochemistry; mouse; 1:100; loading ...; fig 3
Abcam NR1D1 antibody (abcam, ab174309) was used in immunohistochemistry on mouse samples at 1:100 (fig 3). J Cell Sci (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (RS-14)
  • immunohistochemistry knockout validation; mouse; loading ...; fig 3
  • western blot knockout validation; mouse; 1:200; loading ...; fig 2c
Santa Cruz Biotechnology NR1D1 antibody (Santa Cruz, sc-100910) was used in immunohistochemistry knockout validation on mouse samples (fig 3) and in western blot knockout validation on mouse samples at 1:200 (fig 2c). J Cell Sci (2016) ncbi
Invitrogen
rabbit polyclonal
  • western blot; mouse; fig 2d
Invitrogen NR1D1 antibody (ThermoFisher, PA5-29865) was used in western blot on mouse samples (fig 2d). Science (2017) ncbi
rabbit polyclonal
  • chromatin immunoprecipitation; mouse; fig 8c
  • western blot; mouse; fig 3b
In order to test if Rev-erbalpha contributes to brown fat formation, Invitrogen NR1D1 antibody (Thermo Scientific, PA5-29865) was used in chromatin immunoprecipitation on mouse samples (fig 8c) and in western blot on mouse samples (fig 3b). Sci Rep (2015) ncbi
Abnova
mouse monoclonal (4F6)
  • western blot; human; fig s4a
Abnova NR1D1 antibody (Abnova, 4F6) was used in western blot on human samples (fig s4a). Proc Natl Acad Sci U S A (2015) ncbi
Sigma-Aldrich
rabbit polyclonal
  • immunoprecipitation; mouse; 1:50; loading ...; fig 3
Sigma-Aldrich NR1D1 antibody (Sigma, SAB2101632) was used in immunoprecipitation on mouse samples at 1:50 (fig 3). Biol Open (2017) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 3a
In order to assess cyclic alterations of lipid metabolism over a 24-hour period after binge in small heterodimer partner nuclear receptor knockout mice, Sigma-Aldrich NR1D1 antibody (Sigma, SAB2101632) was used in western blot on mouse samples (fig 3a). Am J Pathol (2016) ncbi
EMD Millipore
rabbit polyclonal
  • immunoprecipitation; mouse; loading ...; fig 3a
  • western blot; mouse; loading ...; fig 3a
EMD Millipore NR1D1 antibody (Millipore, AB10130) was used in immunoprecipitation on mouse samples (fig 3a) and in western blot on mouse samples (fig 3a). J Immunol (2014) ncbi
Articles Reviewed
  1. Wang Y, Kuang Z, Yu X, Ruhn K, Kubo M, Hooper L. The intestinal microbiota regulates body composition through NFIL3 and the circadian clock. Science. 2017;357:912-916 pubmed publisher
  2. Akagi R, Akatsu Y, Fisch K, Alvarez Garcia O, Teramura T, Muramatsu Y, et al. Dysregulated circadian rhythm pathway in human osteoarthritis: NR1D1 and BMAL1 suppression alters TGF-? signaling in chondrocytes. Osteoarthritis Cartilage. 2017;25:943-951 pubmed publisher
  3. Chavan R, Preitner N, Okabe T, Strittmatter L, Xu C, Ripperger J, et al. REV-ERB? regulates Fgf21 expression in the liver via hepatic nuclear factor 6. Biol Open. 2017;6:1-7 pubmed publisher
  4. Okabe T, Chavan R, Fonseca Costa S, Brenna A, Ripperger J, Albrecht U. REV-ERB? influences the stability and nuclear localization of the glucocorticoid receptor. J Cell Sci. 2016;129:4143-4154 pubmed
  5. Yang Z, Tsuchiya H, Zhang Y, Lee S, Liu C, Huang Y, et al. REV-ERB? Activates C/EBP Homologous Protein to Control Small Heterodimer Partner-Mediated Oscillation of Alcoholic Fatty Liver. Am J Pathol. 2016;186:2909-2920 pubmed publisher
  6. Debruyne J, Baggs J, Sato T, Hogenesch J. Ubiquitin ligase Siah2 regulates RevErbα degradation and the mammalian circadian clock. Proc Natl Acad Sci U S A. 2015;112:12420-5 pubmed publisher
  7. Nam D, Chatterjee S, Yin H, Liu R, Lee J, Yechoor V, et al. Novel Function of Rev-erbα in Promoting Brown Adipogenesis. Sci Rep. 2015;5:11239 pubmed publisher
  8. Sato S, Sakurai T, Ogasawara J, Takahashi M, Izawa T, Imaizumi K, et al. A circadian clock gene, Rev-erb?, modulates the inflammatory function of macrophages through the negative regulation of Ccl2 expression. J Immunol. 2014;192:407-17 pubmed publisher