This is a Validated Antibody Database (VAD) review about human NPRL2, based on 4 published articles (read how Labome selects the articles), using NPRL2 antibody in all methods. It is aimed to help Labome visitors find the most suited NPRL2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
NPRL2 synonym: FFEVF2; NPR2; NPR2L; TUSC4; GATOR complex protein NPRL2; 2810446G01Rik; G21 protein; NPR2-like protein; gene 21 protein; homologous to yeast nitrogen permease (candidate tumor suppressor); nitrogen permease regulator 2-like protein; tumor suppressor candidate 4

Knockout validation
Santa Cruz Biotechnology
mouse monoclonal (F-3)
  • western blot knockout validation; mouse; fig 2
Santa Cruz Biotechnology NPRL2 antibody (Santa Cruz, sc-376986) was used in western blot knockout validation on mouse samples (fig 2). Cell Rep (2015) ncbi
Santa Cruz Biotechnology
mouse monoclonal (F-3)
  • western blot; human; loading ...; fig 2b
Santa Cruz Biotechnology NPRL2 antibody (Santa Cruz, sc-376986) was used in western blot on human samples (fig 2b). Nature (2017) ncbi
mouse monoclonal (F-3)
  • western blot knockout validation; mouse; fig 2
Santa Cruz Biotechnology NPRL2 antibody (Santa Cruz, sc-376986) was used in western blot knockout validation on mouse samples (fig 2). Cell Rep (2015) ncbi
mouse monoclonal (F-3)
  • western blot; human; fig 3
Santa Cruz Biotechnology NPRL2 antibody (Santa Cruz, sc-376986) was used in western blot on human samples (fig 3). Sci Rep (2015) ncbi
Proteintech Group
rabbit polyclonal
  • immunohistochemistry - paraffin section; human
  • western blot; human
Proteintech Group NPRL2 antibody (Proteintech, 10157-1-AP) was used in immunohistochemistry - paraffin section on human samples and in western blot on human samples . Cancer Res (2015) ncbi
Articles Reviewed
  1. Peng M, Yin N, Li M. SZT2 dictates GATOR control of mTORC1 signalling. Nature. 2017;543:433-437 pubmed publisher
  2. Dutchak P, Laxman S, Estill S, Wang C, Wang Y, Wang Y, et al. Regulation of Hematopoiesis and Methionine Homeostasis by mTORC1 Inhibitor NPRL2. Cell Rep. 2015;12:371-9 pubmed publisher
  3. Kim J, Ro S, Kim M, Park H, Semple I, Park H, et al. Sestrin2 inhibits mTORC1 through modulation of GATOR complexes. Sci Rep. 2015;5:9502 pubmed publisher
  4. Peng Y, Dai H, Wang E, Lin C, Mo W, Peng G, et al. TUSC4 functions as a tumor suppressor by regulating BRCA1 stability. Cancer Res. 2015;75:378-86 pubmed publisher