This is a Validated Antibody Database (VAD) review about human NOD2, based on 5 published articles (read how Labome selects the articles), using NOD2 antibody in all methods. It is aimed to help Labome visitors find the most suited NOD2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
NOD2 synonym: ACUG; BLAU; BLAUS; CARD15; CD; CLR16.3; IBD1; NLRC2; NOD2B; PSORAS1; YAOS

Santa Cruz Biotechnology
mouse monoclonal (2D9)
  • western blot; human; 1:250; loading ...; fig 1c
Santa Cruz Biotechnology NOD2 antibody (Santa Cruz, sc-56168) was used in western blot on human samples at 1:250 (fig 1c). Nat Commun (2018) ncbi
mouse monoclonal (2D9)
  • flow cytometry; human; fig 2
Santa Cruz Biotechnology NOD2 antibody (Santa Cruz, sc-56168) was used in flow cytometry on human samples (fig 2). PLoS ONE (2016) ncbi
mouse monoclonal (2D9)
  • immunohistochemistry - paraffin section; human; 1:600; fig S1
Santa Cruz Biotechnology NOD2 antibody (Santa Cruz, sc 56168) was used in immunohistochemistry - paraffin section on human samples at 1:600 (fig S1). Biomed Res Int (2015) ncbi
Invitrogen
mouse monoclonal (2D9)
  • western blot; mouse; 1:1000; loading ...; fig 1h
  • western blot; human; 1:1000; loading ...; fig s1k
Invitrogen NOD2 antibody (Thermo Fisher, MA1-16611) was used in western blot on mouse samples at 1:1000 (fig 1h) and in western blot on human samples at 1:1000 (fig s1k). Science (2019) ncbi
EMD Millipore
mouse monoclonal (2D9)
  • immunohistochemistry - paraffin section; human; 1:500
  • western blot; human
EMD Millipore NOD2 antibody (Millipore, 2D9) was used in immunohistochemistry - paraffin section on human samples at 1:500 and in western blot on human samples . J Biol Chem (2012) ncbi
Articles Reviewed
  1. Lu Y, Zheng Y, Coyaud E, Zhang C, Selvabaskaran A, Yu Y, et al. Palmitoylation of NOD1 and NOD2 is required for bacterial sensing. Science. 2019;366:460-467 pubmed publisher
  2. Normand S, Waldschmitt N, Neerincx A, Martinez Torres R, Chauvin C, Couturier Maillard A, et al. Proteasomal degradation of NOD2 by NLRP12 in monocytes promotes bacterial tolerance and colonization by enteropathogens. Nat Commun. 2018;9:5338 pubmed publisher
  3. Dagil Y, Arbatsky N, Alkhazova B, L vov V, Mazurov D, Pashenkov M. The Dual NOD1/NOD2 Agonism of Muropeptides Containing a Meso-Diaminopimelic Acid Residue. PLoS ONE. 2016;11:e0160784 pubmed publisher
  4. Leichtle A, Klenke C, Ebmeyer J, Daerr M, Bruchhage K, Hoffmann A, et al. NOD-Like Receptor Signaling in Cholesteatoma. Biomed Res Int. 2015;2015:408169 pubmed publisher
  5. Lecat A, Di Valentin E, Somja J, Jourdan S, Fillet M, Kufer T, et al. The c-Jun N-terminal kinase (JNK)-binding protein (JNKBP1) acts as a negative regulator of NOD2 protein signaling by inhibiting its oligomerization process. J Biol Chem. 2012;287:29213-26 pubmed publisher