This is a Validated Antibody Database (VAD) review about human NLRP1, based on 6 published articles (read how Labome selects the articles), using NLRP1 antibody in all methods. It is aimed to help Labome visitors find the most suited NLRP1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
NLRP1 synonym: AIADK; CARD7; CIDED; CLR17.1; DEFCAP; DEFCAP-L/S; MSPC; NAC; NALP1; PP1044; SLEV1; VAMAS1; NACHT, LRR and PYD domains-containing protein 1; NACHT, LRR and PYD containing protein 1; NACHT, leucine rich repeat and PYD (pyrin domain) containing 1; NACHT, leucine rich repeat and PYD containing 1; caspase recruitment domain protein 7; caspase recruitment domain-containing protein 7; death effector filament-forming Ced-4-like apoptosis protein; nucleotide-binding domain and caspase recruitment domain; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 1

Abcam
rabbit polyclonal
  • immunohistochemistry; mouse; 1:200; fig 5
  • western blot; mouse; fig 3A
In order to study the amelioration of neuropathic pain by down-regulating spinal IL-1-beta via suppressing JAK2-STAT3 signaling and astroglial NALP1 inflammasome by curcumin, Abcam NLRP1 antibody (Abcam, ab98181) was used in immunohistochemistry on mouse samples at 1:200 (fig 5) and in western blot on mouse samples (fig 3A). Sci Rep (2016) ncbi
mouse monoclonal (Nalpy1-4)
  • immunohistochemistry - paraffin section; human; 1:50
Abcam NLRP1 antibody (Abcam, ab16091) was used in immunohistochemistry - paraffin section on human samples at 1:50. Br J Dermatol (2014) ncbi
R&D Systems
sheep polyclonal
  • western blot; human
R&D Systems NLRP1 antibody (R&D Systems, AF6788) was used in western blot on human samples . PLoS ONE (2015) ncbi
Cell Signaling Technology
rabbit polyclonal
  • western blot; human
Cell Signaling Technology NLRP1 antibody (Cell Signaling, 4990) was used in western blot on human samples . Biol Reprod (2014) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology NLRP1 antibody (Cell Signaling Technology, 4990S) was used in western blot on human samples . J Rheumatol (2014) ncbi
MBL International
monoclonal (5F7)
  • western blot; human; fig 4a
MBL International NLRP1 antibody (Medical and Biological Laboratories, M032-3) was used in western blot on human samples (fig 4a). Mol Cancer (2014) ncbi
Articles Reviewed
  1. Liu S, Li Q, Zhang M, Mao Ying Q, Hu L, Wu G, et al. Curcumin ameliorates neuropathic pain by down-regulating spinal IL-1β via suppressing astroglial NALP1 inflammasome and JAK2-STAT3 signalling. Sci Rep. 2016;6:28956 pubmed publisher
  2. D Osualdo A, Anania V, Yu K, Lill J, Kaufman R, Matsuzawa S, et al. Transcription Factor ATF4 Induces NLRP1 Inflammasome Expression during Endoplasmic Reticulum Stress. PLoS ONE. 2015;10:e0130635 pubmed publisher
  3. Harashima N, Minami T, Uemura H, Harada M. Transfection of poly(I:C) can induce reactive oxygen species-triggered apoptosis and interferon-β-mediated growth arrest in human renal cell carcinoma cells via innate adjuvant receptors and the 2-5A system. Mol Cancer. 2014;13:217 pubmed publisher
  4. Marie J, Kovacs D, Pain C, Jouary T, Cota C, Vergier B, et al. Inflammasome activation and vitiligo/nonsegmental vitiligo progression. Br J Dermatol. 2014;170:816-23 pubmed publisher
  5. Hoang M, Potter J, Gysler S, Han C, Guller S, Norwitz E, et al. Human fetal membranes generate distinct cytokine profiles in response to bacterial Toll-like receptor and nod-like receptor agonists. Biol Reprod. 2014;90:39 pubmed publisher
  6. Yang Q, Yu C, Yang Z, Wei Q, Mu K, Zhang Y, et al. Deregulated NLRP3 and NLRP1 inflammasomes and their correlations with disease activity in systemic lupus erythematosus. J Rheumatol. 2014;41:444-52 pubmed publisher