This is a Validated Antibody Database (VAD) review about human NLGN2, based on 13 published articles (read how Labome selects the articles), using NLGN2 antibody in all methods. It is aimed to help Labome visitors find the most suited NLGN2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
NLGN2 synonym: neuroligin-2

Synaptic Systems
mouse monoclonal (5E6)
  • western blot; mouse; 1:1000; fig 2c
Synaptic Systems NLGN2 antibody (Synaptic Systems, 129511) was used in western blot on mouse samples at 1:1000 (fig 2c). Mol Neurobiol (2018) ncbi
mouse monoclonal (5E6)
  • western blot; mouse; 1:3000; loading ...; fig 4c
Synaptic Systems NLGN2 antibody (Synaptic Systems, 129 511) was used in western blot on mouse samples at 1:3000 (fig 4c). Nat Commun (2017) ncbi
rabbit polyclonal (/)
  • western blot; mouse; loading ...; fig 1
Synaptic Systems NLGN2 antibody (Synaptic Systems, 129 202) was used in western blot on mouse samples (fig 1). elife (2017) ncbi
mouse monoclonal (5E6)
  • western blot; rat; 1 ug/ml; loading ...; tbl 1
In order to develop a novel synaptic junction preparation to characterize components of the synaptic cleft, Synaptic Systems NLGN2 antibody (Synaptic Systems, 129 511) was used in western blot on rat samples at 1 ug/ml (tbl 1). PLoS ONE (2017) ncbi
rabbit polyclonal (/)
  • western blot; rat; 1:10,000; loading ...; fig 7b
Synaptic Systems NLGN2 antibody (Synaptic Systems, 129203) was used in western blot on rat samples at 1:10,000 (fig 7b). Front Mol Neurosci (2017) ncbi
rabbit polyclonal (/)
  • western blot; mouse; 1:1000; fig 11
In order to demonstrate that synGAP-alpha1 regulates postsynaptic density composition by restricting binding to the PDZ domains of PSD-95, Synaptic Systems NLGN2 antibody (Synaptic Systems, 129202) was used in western blot on mouse samples at 1:1000 (fig 11). elife (2016) ncbi
rabbit polyclonal (/)
  • western blot; mouse; 1:500; loading ...; fig 8a
Synaptic Systems NLGN2 antibody (Synaptic Systems, 129203) was used in western blot on mouse samples at 1:500 (fig 8a). J Neurosci (2016) ncbi
rabbit polyclonal (/)
  • immunohistochemistry - free floating section; mouse; 1:5000; fig 3
Synaptic Systems NLGN2 antibody (Synaptic Systems, 129203) was used in immunohistochemistry - free floating section on mouse samples at 1:5000 (fig 3). Front Synaptic Neurosci (2015) ncbi
rabbit polyclonal (/)
  • western blot; rat
In order to test if synaptic contacts between neurons aid propagation of Tau pathology, Synaptic Systems NLGN2 antibody (Synaptic Systems, 129203) was used in western blot on rat samples . Cell Rep (2015) ncbi
rabbit polyclonal (/)
  • immunohistochemistry - free floating section; mouse; 1:1000; loading ...; fig 3f
Synaptic Systems NLGN2 antibody (Synaptic Systems, 129202) was used in immunohistochemistry - free floating section on mouse samples at 1:1000 (fig 3f). Psychoneuroendocrinology (2015) ncbi
rabbit polyclonal (/)
  • western blot; human; fig 5
Synaptic Systems NLGN2 antibody (Synaptic System, 129202) was used in western blot on human samples (fig 5). Nat Commun (2014) ncbi
Abcam
rabbit polyclonal
  • western blot; mouse; loading ...; fig 5f
Abcam NLGN2 antibody (Abcam, ab177107) was used in western blot on mouse samples (fig 5f). EMBO J (2018) ncbi
EMD Millipore
rabbit polyclonal
  • western blot; mouse; fig 7
In order to analyze selective partitioning into complexes and supercomplexes during synapse maturation by NMDA receptors, EMD Millipore NLGN2 antibody (Millipore, ab15510) was used in western blot on mouse samples (fig 7). Nat Commun (2016) ncbi
Articles Reviewed
  1. Chmielewska J, Kuzniewska B, Milek J, Urbanska K, Dziembowska M. Neuroligin 1, 2, and 3 Regulation at the Synapse: FMRP-Dependent Translation and Activity-Induced Proteolytic Cleavage. Mol Neurobiol. 2018;: pubmed publisher
  2. Kanellopoulos A, Koenig J, Huang H, Pyrski M, Millet Q, Lolignier S, et al. Mapping protein interactions of sodium channel NaV1.7 using epitope-tagged gene-targeted mice. EMBO J. 2018;37:427-445 pubmed publisher
  3. Tanabe Y, Naito Y, Vasuta C, Lee A, Soumounou Y, Linhoff M, et al. IgSF21 promotes differentiation of inhibitory synapses via binding to neurexin2?. Nat Commun. 2017;8:408 pubmed publisher
  4. Martenson J, Yamasaki T, Chaudhury N, Albrecht D, Tomita S. Assembly rules for GABAA receptor complexes in the brain. elife. 2017;6: pubmed publisher
  5. Burch A, Tao Cheng J, Dosemeci A. A novel synaptic junction preparation for the identification and characterization of cleft proteins. PLoS ONE. 2017;12:e0174895 pubmed publisher
  6. Li J, Xie X, Li Y, Liu X, Liao X, Su Y, et al. Differential Behavioral and Neurobiological Effects of Chronic Corticosterone Treatment in Adolescent and Adult Rats. Front Mol Neurosci. 2017;10:25 pubmed publisher
  7. Walkup W, Mastro T, Schenker L, Vielmetter J, Hu R, Iancu A, et al. A model for regulation by SynGAP-?1 of binding of synaptic proteins to PDZ-domain 'Slots' in the postsynaptic density. elife. 2016;5: pubmed publisher
  8. Zhang B, Sudhof T. Neuroligins Are Selectively Essential for NMDAR Signaling in Cerebellar Stellate Interneurons. J Neurosci. 2016;36:9070-83 pubmed publisher
  9. Frank R, Komiyama N, Ryan T, Zhu F, O Dell T, Grant S. NMDA receptors are selectively partitioned into complexes and supercomplexes during synapse maturation. Nat Commun. 2016;7:11264 pubmed publisher
  10. Ye R, Quinlan M, Iwamoto H, Wu H, Green N, Jetter C, et al. Physical Interactions and Functional Relationships of Neuroligin 2 and Midbrain Serotonin Transporters. Front Synaptic Neurosci. 2015;7:20 pubmed publisher
  11. Calafate S, Buist A, Miskiewicz K, Vijayan V, Daneels G, De Strooper B, et al. Synaptic Contacts Enhance Cell-to-Cell Tau Pathology Propagation. Cell Rep. 2015;11:1176-83 pubmed publisher
  12. Kohl C, Wang X, Grosse J, Fournier C, Harbich D, Westerholz S, et al. Hippocampal neuroligin-2 links early-life stress with impaired social recognition and increased aggression in adult mice. Psychoneuroendocrinology. 2015;55:128-43 pubmed publisher
  13. Antonelli R, Pizzarelli R, Pedroni A, Fritschy J, Del Sal G, Cherubini E, et al. Pin1-dependent signalling negatively affects GABAergic transmission by modulating neuroligin2/gephyrin interaction. Nat Commun. 2014;5:5066 pubmed publisher