This is a Validated Antibody Database (VAD) review about human NFE2L2, based on 141 published articles (read how Labome selects the articles), using NFE2L2 antibody in all methods. It is aimed to help Labome visitors find the most suited NFE2L2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
NFE2L2 synonym: HEBP1; IMDDHH; NRF2; Nrf-2

Knockout validation
Abcam
domestic rabbit polyclonal
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 8c
  • western blot; human; 1:1000; loading ...; fig 2c
Abcam NFE2L2 antibody (Abcam, ab137550) was used in western blot knockout validation on mouse samples at 1:1000 (fig 8c) and in western blot on human samples at 1:1000 (fig 2c). Oxid Med Cell Longev (2021) ncbi
Abcam
domestic rabbit polyclonal
  • western blot knockout validation; mouse; loading ...; fig 4d
Abcam NFE2L2 antibody (Abcam, ab31163) was used in western blot knockout validation on mouse samples (fig 4d). Neuroscience (2018) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D1Z9C)
  • western blot knockout validation; mouse; 1:2000; loading ...; fig s1c
Cell Signaling Technology NFE2L2 antibody (Cell Signaling, 12721) was used in western blot knockout validation on mouse samples at 1:2000 (fig s1c). Front Oncol (2021) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D1Z9C)
  • western blot knockout validation; human; loading ...; fig 1g
Cell Signaling Technology NFE2L2 antibody (Cell Signaling Technology, 12721 S) was used in western blot knockout validation on human samples (fig 1g). iScience (2021) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D1Z9C)
  • western blot knockout validation; mouse; 1:500; fig 2
Cell Signaling Technology NFE2L2 antibody (Cell Signaling, D1Z9C) was used in western blot knockout validation on mouse samples at 1:500 (fig 2). Proc Natl Acad Sci U S A (2014) ncbi
Abcam
domestic rabbit monoclonal (EP1808Y)
  • western blot; human; loading ...; fig 1e
Abcam NFE2L2 antibody (Abcam, ab62352) was used in western blot on human samples (fig 1e). Int J Mol Sci (2022) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:100; loading ...; fig 4b
Abcam NFE2L2 antibody (Abcam, ab31163) was used in immunohistochemistry on mouse samples at 1:100 (fig 4b). Int J Mol Sci (2022) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 7i
  • western blot; mouse; 1:1000; loading ...; fig 7a
Abcam NFE2L2 antibody (Abcam, ab137550) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig 7i) and in western blot on mouse samples at 1:1000 (fig 7a). J Cell Mol Med (2022) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 4h
Abcam NFE2L2 antibody (Abcam, ab137550) was used in western blot on mouse samples (fig 4h). Sci Adv (2022) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:2000; loading ...; fig 2g
Abcam NFE2L2 antibody (Abcam, ab31163) was used in western blot on mouse samples at 1:2000 (fig 2g). Redox Biol (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig s9a
Abcam NFE2L2 antibody (Abcam, ab137550) was used in western blot on mouse samples at 1:1000 (fig s9a). Nat Commun (2021) ncbi
domestic rabbit monoclonal (EP1808Y)
  • western blot; mouse; 1:400; fig 2d
Abcam NFE2L2 antibody (Abcam, ab62352) was used in western blot on mouse samples at 1:400 (fig 2d). Antioxidants (Basel) (2021) ncbi
domestic rabbit monoclonal (EP1808Y)
  • immunohistochemistry; mouse; 1:200; loading ...; fig 3b
  • western blot; mouse; 1:1000; loading ...; fig 3a
Abcam NFE2L2 antibody (Abcam, ab62352) was used in immunohistochemistry on mouse samples at 1:200 (fig 3b) and in western blot on mouse samples at 1:1000 (fig 3a). EBioMedicine (2021) ncbi
domestic rabbit monoclonal (EP1808Y)
  • western blot; guinea pig; 1:1000; loading ...; fig 3d
Abcam NFE2L2 antibody (Abcam, ab62352) was used in western blot on guinea pig samples at 1:1000 (fig 3d). Antioxidants (Basel) (2021) ncbi
domestic rabbit monoclonal (EP1809Y)
  • immunohistochemistry; human; 1:400; loading ...; fig 1b
Abcam NFE2L2 antibody (abcam, EP1809Y) was used in immunohistochemistry on human samples at 1:400 (fig 1b). Acta Neuropathol Commun (2021) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 3c
Abcam NFE2L2 antibody (Abcam, Ab137550) was used in western blot on human samples (fig 3c). Antioxidants (Basel) (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; rat; loading ...; fig 5i
  • immunocytochemistry; rat; loading ...; fig 3j
  • western blot; rat; loading ...; fig 4j, 5k
Abcam NFE2L2 antibody (Abcam, ab137550) was used in immunohistochemistry - paraffin section on rat samples (fig 5i), in immunocytochemistry on rat samples (fig 3j) and in western blot on rat samples (fig 4j, 5k). Front Pharmacol (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 4a
Abcam NFE2L2 antibody (Abcam, ab137550) was used in western blot on mouse samples at 1:1000 (fig 4a). Mol Med Rep (2021) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 6j
Abcam NFE2L2 antibody (Abcam, ab137550) was used in western blot on human samples (fig 6j). Cell Death Dis (2021) ncbi
domestic rabbit monoclonal (EP1808Y)
  • western blot; human; 1:5000; loading ...; fig 5j, 5m
Abcam NFE2L2 antibody (Abcam, ab62352) was used in western blot on human samples at 1:5000 (fig 5j, 5m). J Cell Mol Med (2021) ncbi
domestic rabbit monoclonal (EP1809Y)
  • western blot; human; 1:5000; loading ...; fig 5j, 5m
Abcam NFE2L2 antibody (Abcam, ab76026) was used in western blot on human samples at 1:5000 (fig 5j, 5m). J Cell Mol Med (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 3a
Abcam NFE2L2 antibody (Abcam, Ab137550) was used in western blot on mouse samples at 1:1000 (fig 3a). Cell Death Dis (2021) ncbi
domestic rabbit monoclonal (EP1808Y)
  • western blot; mouse; 1:3000; loading ...; fig 7j
Abcam NFE2L2 antibody (Abcam, ab62352) was used in western blot on mouse samples at 1:3000 (fig 7j). Cell Death Dis (2021) ncbi
domestic rabbit monoclonal (EP1808Y)
  • western blot; human; loading ...
Abcam NFE2L2 antibody (Abcam, ab62352) was used in western blot on human samples . Theranostics (2021) ncbi
domestic rabbit monoclonal (EP1808Y)
  • western blot; human; loading ...; fig 3c
Abcam NFE2L2 antibody (Abcam, ab62352) was used in western blot on human samples (fig 3c). Oncol Rep (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 5a
  • western blot; human; 1:1000; loading ...; fig 4a
Abcam NFE2L2 antibody (Abcam, ab31163) was used in western blot on mouse samples at 1:1000 (fig 5a) and in western blot on human samples at 1:1000 (fig 4a). Aging (Albany NY) (2021) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 3c
  • western blot; rat; loading ...; fig 7c
Abcam NFE2L2 antibody (Abcam, ab137550) was used in western blot on human samples at 1:1000 (fig 3c) and in western blot on rat samples (fig 7c). Ann Transl Med (2021) ncbi
domestic rabbit polyclonal
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 8c
  • western blot; human; 1:1000; loading ...; fig 2c
Abcam NFE2L2 antibody (Abcam, ab137550) was used in western blot knockout validation on mouse samples at 1:1000 (fig 8c) and in western blot on human samples at 1:1000 (fig 2c). Oxid Med Cell Longev (2021) ncbi
domestic rabbit polyclonal
  • immunoprecipitation; mouse; loading ...; fig 3f
  • western blot; mouse; 1:600; loading ...; fig 3b
Abcam NFE2L2 antibody (Abcam, ab137550) was used in immunoprecipitation on mouse samples (fig 3f) and in western blot on mouse samples at 1:600 (fig 3b). Redox Biol (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 2j
Abcam NFE2L2 antibody (Abcam, ab31163) was used in western blot on mouse samples at 1:1000 (fig 2j). J Neurosci (2021) ncbi
domestic rabbit monoclonal (EP1808Y)
  • western blot; mouse; 1:1000; loading ...
Abcam NFE2L2 antibody (Abcam, ab62352) was used in western blot on mouse samples at 1:1000. Cell Mol Gastroenterol Hepatol (2021) ncbi
domestic rabbit monoclonal (EP1808Y)
  • western blot; mouse; 1:1000; loading ...; fig 1k
Abcam NFE2L2 antibody (Abcam, ab62352) was used in western blot on mouse samples at 1:1000 (fig 1k). Commun Biol (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:200; loading ...; fig 4a
Abcam NFE2L2 antibody (Abcam, ab31163) was used in western blot on mouse samples at 1:200 (fig 4a). Antioxidants (Basel) (2020) ncbi
domestic rabbit monoclonal (EP1809Y)
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 9e
  • western blot; mouse; 1:1000; loading ...; fig 5a
Abcam NFE2L2 antibody (Abcam, ab76026) was used in immunohistochemistry - paraffin section on mouse samples (fig 9e) and in western blot on mouse samples at 1:1000 (fig 5a). Aging (Albany NY) (2020) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; human; 1:200; loading ...; fig 1a
Abcam NFE2L2 antibody (Abcam, ab137550) was used in immunohistochemistry on human samples at 1:200 (fig 1a). Aging (Albany NY) (2020) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 1c
  • western blot; human; 1:1000; loading ...; fig 1b
Abcam NFE2L2 antibody (Abcam, ab137550) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 1c) and in western blot on human samples at 1:1000 (fig 1b). EBioMedicine (2020) ncbi
domestic rabbit polyclonal
  • western blot; rat; loading ...; fig 4d
Abcam NFE2L2 antibody (Abcam, ab137550) was used in western blot on rat samples (fig 4d). Int J Mol Sci (2020) ncbi
domestic rabbit monoclonal (EP1808Y)
  • western blot; human; 1:1000; loading ...; fig 8e
Abcam NFE2L2 antibody (Abcam, ab62352) was used in western blot on human samples at 1:1000 (fig 8e). Int J Mol Med (2020) ncbi
domestic rabbit monoclonal (EP1808Y)
  • western blot; mouse; 1:1000; loading ...; fig 7a
Abcam NFE2L2 antibody (Abcam, Ab62352) was used in western blot on mouse samples at 1:1000 (fig 7a). elife (2020) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:2000; loading ...; fig 5b
Abcam NFE2L2 antibody (Abcam, ab31163) was used in western blot on mouse samples at 1:2000 (fig 5b). Antioxidants (Basel) (2020) ncbi
domestic rabbit polyclonal
  • western blot; rat; 1:1000; loading ...; fig 5e
Abcam NFE2L2 antibody (Abcam, ab31163) was used in western blot on rat samples at 1:1000 (fig 5e). Oxid Med Cell Longev (2020) ncbi
domestic rabbit monoclonal (EP1809Y)
  • immunocytochemistry; human; loading ...; fig 8c
  • western blot; human; loading ...; fig 8b
Abcam NFE2L2 antibody (Abcam, ab76026) was used in immunocytochemistry on human samples (fig 8c) and in western blot on human samples (fig 8b). J Clin Med (2020) ncbi
domestic rabbit polyclonal
  • western blot; rat; loading ...; fig 6f
Abcam NFE2L2 antibody (Abcam, ab137550) was used in western blot on rat samples (fig 6f). Aging (Albany NY) (2020) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 2d
Abcam NFE2L2 antibody (Abcam, ab31163) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 2d). Breast Cancer Res Treat (2020) ncbi
domestic rabbit monoclonal (EP1808Y)
  • western blot; mouse; loading ...; fig 3b
Abcam NFE2L2 antibody (Abcam, ab62352) was used in western blot on mouse samples (fig 3b). Exp Gerontol (2020) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; fig 1e
  • western blot; mouse; loading ...; fig 1f
Abcam NFE2L2 antibody (Abcam, ab31163) was used in immunohistochemistry on mouse samples (fig 1e) and in western blot on mouse samples (fig 1f). Cell Metab (2019) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:600; loading ...; fig 6f, 5f, 5s2b
Abcam NFE2L2 antibody (Abcam, ab137550) was used in immunohistochemistry - paraffin section on human samples at 1:600 (fig 6f, 5f, 5s2b). elife (2019) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:500; loading ...; fig s5b
Abcam NFE2L2 antibody (Abcam, ab137550) was used in immunohistochemistry - frozen section on mouse samples at 1:500 (fig s5b). Atherosclerosis (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 6a
Abcam NFE2L2 antibody (Abcam, ab137550) was used in western blot on human samples at 1:1000 (fig 6a). Cell Rep (2019) ncbi
domestic rabbit monoclonal (EP1808Y)
  • western blot; human; loading ...; fig 4d
Abcam NFE2L2 antibody (Abcam, ab62352) was used in western blot on human samples (fig 4d). Cancers (Basel) (2018) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 3h
Abcam NFE2L2 antibody (Abcam, ab31163) was used in western blot on mouse samples at 1:1000 (fig 3h). Biochem Biophys Res Commun (2018) ncbi
domestic rabbit monoclonal (EP1808Y)
  • western blot; human; loading ...; fig 6a
Abcam NFE2L2 antibody (Abcam, ab62352) was used in western blot on human samples (fig 6a). EMBO J (2018) ncbi
domestic rabbit polyclonal
  • western blot knockout validation; mouse; loading ...; fig 4d
Abcam NFE2L2 antibody (Abcam, ab31163) was used in western blot knockout validation on mouse samples (fig 4d). Neuroscience (2018) ncbi
domestic rabbit monoclonal (EP1808Y)
  • immunohistochemistry; mouse; loading ...; fig 1a
Abcam NFE2L2 antibody (Abcam, ab62352) was used in immunohistochemistry on mouse samples (fig 1a). Neuroscience (2018) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; fig 4h
Abcam NFE2L2 antibody (Abcam, ab137550) was used in western blot on mouse samples at 1:1000 (fig 4h). Biochem Biophys Res Commun (2018) ncbi
domestic rabbit monoclonal (EP1808Y)
  • western blot; human; loading ...; fig 4e
Abcam NFE2L2 antibody (Abcam, ab62352) was used in western blot on human samples (fig 4e). Oncogene (2017) ncbi
domestic rabbit monoclonal (EP1808Y)
  • western blot; human; 1:1000; loading ...; fig 3a
Abcam NFE2L2 antibody (Abcam, ab62352) was used in western blot on human samples at 1:1000 (fig 3a). Int J Mol Sci (2017) ncbi
domestic rabbit monoclonal (EP1808Y)
  • western blot; human; loading ...; fig 6a
Abcam NFE2L2 antibody (Abcam, ab62352) was used in western blot on human samples (fig 6a). Nat Chem Biol (2017) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:100; loading ...; fig 2a
  • western blot; mouse; 1:1000; loading ...; fig 2d
Abcam NFE2L2 antibody (Abcam, ab31163) was used in immunohistochemistry on mouse samples at 1:100 (fig 2a) and in western blot on mouse samples at 1:1000 (fig 2d). Endocrinology (2017) ncbi
domestic rabbit monoclonal (EP1808Y)
  • chromatin immunoprecipitation; human; fig 4b
Abcam NFE2L2 antibody (Abcam, ab62352) was used in chromatin immunoprecipitation on human samples (fig 4b). Mol Carcinog (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 5a
In order to find that continued 26S proteasome dysfunction in mouse brain cortical neurons causes paranuclear accumulation of fragmented dysfunctional mitochondria, associated with earlier recruitment of Parkin and lysine 48-linked ubiquitination of mitochond, Abcam NFE2L2 antibody (Abcam, ab31163) was used in western blot on mouse samples (fig 5a). Cell Death Dis (2017) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; mouse; 1:150; loading ...; fig 3e
  • western blot; mouse; 1:500; loading ...; fig 3b
Abcam NFE2L2 antibody (Abcam, ab31163) was used in immunocytochemistry on mouse samples at 1:150 (fig 3e) and in western blot on mouse samples at 1:500 (fig 3b). Sci Rep (2016) ncbi
domestic rabbit monoclonal (EP1809Y)
  • western blot; human; fig 5
In order to elucidate the mechanism by which esculetin induces cytotoxicity in cancer cells, Abcam NFE2L2 antibody (abcam, ab76026) was used in western blot on human samples (fig 5). Mol Cancer (2016) ncbi
domestic rabbit monoclonal (EP1808Y)
  • chromatin immunoprecipitation; human; loading ...; fig 9f
In order to research the oncogenic effect of NRF2 and its mechanism, Abcam NFE2L2 antibody (Abcam, ab62352) was used in chromatin immunoprecipitation on human samples (fig 9f). Oncotarget (2016) ncbi
domestic rabbit monoclonal (EP1808Y)
  • western blot; human; 1:1000; fig 5
Abcam NFE2L2 antibody (Abcam, ab62352) was used in western blot on human samples at 1:1000 (fig 5). J Hematol Oncol (2016) ncbi
domestic rabbit monoclonal (EP1809Y)
  • western blot; human; loading ...; fig s5
In order to test if blockade of glutathione and thioredoxin eliminates cancer stem cells using colorectal carcinoma samples, Abcam NFE2L2 antibody (Abcam, 76026) was used in western blot on human samples (fig s5). Cancer Med (2016) ncbi
domestic rabbit monoclonal (EP1808Y)
  • immunoprecipitation; human; loading ...; fig s5a
  • immunocytochemistry; human; loading ...; fig s5h, s5i
  • western blot; human; 1:500; loading ...; fig 5d
Abcam NFE2L2 antibody (Abcam, ab62352) was used in immunoprecipitation on human samples (fig s5a), in immunocytochemistry on human samples (fig s5h, s5i) and in western blot on human samples at 1:500 (fig 5d). Nat Cell Biol (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:500; fig 4g
In order to determine inhibition of acute liver failure by microRNA-125b-5p mimic, Abcam NFE2L2 antibody (Abcam, 31163) was used in western blot on mouse samples at 1:500 (fig 4g). Nat Commun (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; guinea pig; 1:100; fig 4
  • immunocytochemistry; human; 1:100; fig 7
Abcam NFE2L2 antibody (abcam, ab31163) was used in immunohistochemistry - frozen section on guinea pig samples at 1:100 (fig 4) and in immunocytochemistry on human samples at 1:100 (fig 7). Sci Rep (2016) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; rat; fig 7
  • western blot; rat; 1:200; fig 6
Abcam NFE2L2 antibody (Abcam, ab31163) was used in immunocytochemistry on rat samples (fig 7) and in western blot on rat samples at 1:200 (fig 6). Int J Mol Med (2016) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; mouse; 1:100; fig s2
Abcam NFE2L2 antibody (Abcam, ab31163) was used in immunocytochemistry on mouse samples at 1:100 (fig s2). Sci Rep (2016) ncbi
domestic rabbit monoclonal (EP1809Y)
  • RNA immunoprecipitation; human; loading ...; fig 3d
  • western blot; human; loading ...; fig 2d
Abcam NFE2L2 antibody (Abcam, EP1808Y) was used in RNA immunoprecipitation on human samples (fig 3d) and in western blot on human samples (fig 2d). Oncogene (2016) ncbi
domestic rabbit monoclonal (EP1809Y)
  • immunocytochemistry; human; fig 5
  • western blot; human; fig 4
Abcam NFE2L2 antibody (Abcam, ab76026) was used in immunocytochemistry on human samples (fig 5) and in western blot on human samples (fig 4). Oxid Med Cell Longev (2016) ncbi
domestic rabbit monoclonal (EP1808Y)
  • western blot; human; 1:1000; fig 4
Abcam NFE2L2 antibody (Abcam, ab62352) was used in western blot on human samples at 1:1000 (fig 4). Cell Res (2016) ncbi
domestic rabbit monoclonal (EP1808Y)
  • western blot; human; fig 1
In order to examine the effects of brusatol on the cellular proteome in a mutant non-small cell lung cancer cell line, Abcam NFE2L2 antibody (Abcam, ab62352) was used in western blot on human samples (fig 1). Mol Cell Proteomics (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:200; fig s5
Abcam NFE2L2 antibody (Abcam, ab137550) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig s5). Cancer Sci (2016) ncbi
domestic rabbit monoclonal (EP1808Y)
  • western blot; human; fig s6
Abcam NFE2L2 antibody (abcam, ab62352) was used in western blot on human samples (fig s6). Nature (2015) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human; loading ...; fig 4a
  • western blot; human; loading ...; fig 4e
Abcam NFE2L2 antibody (Abcam, ab31163) was used in immunocytochemistry on human samples (fig 4a) and in western blot on human samples (fig 4e). J Neurochem (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 3d
Abcam NFE2L2 antibody (Abcam, ab137550) was used in western blot on human samples at 1:1000 (fig 3d). J Pathol (2016) ncbi
domestic rabbit monoclonal (EP1808Y)
  • western blot; human; 1:1000; fig 1B
Abcam NFE2L2 antibody (Abcam, ab62352) was used in western blot on human samples at 1:1000 (fig 1B). Antioxid Redox Signal (2015) ncbi
domestic rabbit monoclonal (EP1809Y)
  • western blot; mouse; fig 7a
Abcam NFE2L2 antibody (Abcam, ab76026) was used in western blot on mouse samples (fig 7a). J Inflamm (Lond) (2015) ncbi
domestic rabbit monoclonal (EP1808Y)
  • immunohistochemistry - paraffin section; human; 1:100; fig 1
Abcam NFE2L2 antibody (Abcam, ab62352) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 1). Acta Neuropathol (2015) ncbi
domestic rabbit monoclonal (EP1808Y)
  • western blot; human; fig 4
Abcam NFE2L2 antibody (Abcam, ab62352) was used in western blot on human samples (fig 4). Oncotarget (2015) ncbi
domestic rabbit monoclonal (EP1808Y)
  • chromatin immunoprecipitation; human; loading ...; fig 5d
Abcam NFE2L2 antibody (Abcam, AB 62352) was used in chromatin immunoprecipitation on human samples (fig 5d). Mol Cell Biol (2015) ncbi
domestic rabbit monoclonal (EP1808Y)
  • western blot; human; fig 2
In order to investigate the roles and mechanisms of the RSPO-LGR system in oncogenesis, Abcam NFE2L2 antibody (Abcam, ab62352) was used in western blot on human samples (fig 2). Oncogene (2015) ncbi
domestic rabbit monoclonal (EP1809Y)
  • western blot; mouse; 1:500
In order to examine the role of insulin and IGF-1 on the mitochondria of striatal cells derived from HD knock-in mice, Abcam NFE2L2 antibody (Abcam, ab76026) was used in western blot on mouse samples at 1:500. Free Radic Biol Med (2014) ncbi
domestic rabbit monoclonal (EP1809Y)
  • western blot; rat
Abcam NFE2L2 antibody (Abcam, ab76026) was used in western blot on rat samples . Free Radic Biol Med (2014) ncbi
domestic rabbit monoclonal (EP1808Y)
  • western blot; mouse
Abcam NFE2L2 antibody (Abcam, ab62352) was used in western blot on mouse samples . J Biol Chem (2014) ncbi
Santa Cruz Biotechnology
mouse monoclonal (A-10)
  • western blot; mouse; loading ...; fig 3a
Santa Cruz Biotechnology NFE2L2 antibody (Santa, sc-365,949) was used in western blot on mouse samples (fig 3a). Redox Biol (2022) ncbi
mouse monoclonal (A-10)
  • western blot; mouse; 1:200; loading ...; fig 5a
Santa Cruz Biotechnology NFE2L2 antibody (Santa Cruz, sc-365949) was used in western blot on mouse samples at 1:200 (fig 5a). Antioxidants (Basel) (2021) ncbi
mouse monoclonal (A-10)
  • immunocytochemistry; human; 1:50; loading ...; fig 4a
Santa Cruz Biotechnology NFE2L2 antibody (Santa Cruz, sc-365949) was used in immunocytochemistry on human samples at 1:50 (fig 4a). Antioxidants (Basel) (2021) ncbi
mouse monoclonal (A-10)
  • western blot; mouse; 1:1000; loading ...; fig 2f
Santa Cruz Biotechnology NFE2L2 antibody (Santa Cruz, sc-365949) was used in western blot on mouse samples at 1:1000 (fig 2f). Antioxidants (Basel) (2021) ncbi
mouse monoclonal (A-10)
  • immunocytochemistry; mouse; loading ...; fig 5d
  • western blot; mouse; 1:1000; loading ...; fig 5a
Santa Cruz Biotechnology NFE2L2 antibody (Santa Cruz, sc-365949) was used in immunocytochemistry on mouse samples (fig 5d) and in western blot on mouse samples at 1:1000 (fig 5a). Aging (Albany NY) (2020) ncbi
mouse monoclonal (A-10)
  • immunocytochemistry; human; loading ...; fig 6b
  • western blot; human; loading ...; fig 6a
Santa Cruz Biotechnology NFE2L2 antibody (Santa Cruz Biotechnology, sc-365949) was used in immunocytochemistry on human samples (fig 6b) and in western blot on human samples (fig 6a). Antioxidants (Basel) (2020) ncbi
mouse monoclonal (A-10)
  • immunohistochemistry - paraffin section; mouse; 1:400; loading ...; fig 8c
  • western blot; mouse; 1:1000; loading ...; fig 8a
Santa Cruz Biotechnology NFE2L2 antibody (Santa Cruz, sc-365949) was used in immunohistochemistry - paraffin section on mouse samples at 1:400 (fig 8c) and in western blot on mouse samples at 1:1000 (fig 8a). Front Pharmacol (2019) ncbi
mouse monoclonal (A-10)
  • western blot; human; loading ...; fig s10
In order to identify compounds that inhibit the proteasome 19S subunit Rpn11, Santa Cruz Biotechnology NFE2L2 antibody (SantaCruz, sc-365949) was used in western blot on human samples (fig s10). Nat Chem Biol (2017) ncbi
mouse monoclonal (A-10)
  • western blot; mouse; 1:1500; loading ...; fig 8a
Santa Cruz Biotechnology NFE2L2 antibody (Santa Cruz, sc-365949) was used in western blot on mouse samples at 1:1500 (fig 8a). Exp Ther Med (2016) ncbi
mouse monoclonal (A-10)
  • western blot; rat; loading ...; fig 7a
Santa Cruz Biotechnology NFE2L2 antibody (Santa Cruz, sc-365949) was used in western blot on rat samples (fig 7a). Int J Mol Med (2016) ncbi
mouse monoclonal (A-10)
  • immunohistochemistry - paraffin section; human; 1:200; fig 2
  • western blot; human; 1:500; fig 1
Santa Cruz Biotechnology NFE2L2 antibody (Santa Cruz Biotechnology, sc-365949) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig 2) and in western blot on human samples at 1:500 (fig 1). BMC Cancer (2015) ncbi
mouse monoclonal (A-10)
  • western blot; human
Santa Cruz Biotechnology NFE2L2 antibody (Santa Cruz Biotechnology, sc-365949) was used in western blot on human samples . Biochim Biophys Acta (2014) ncbi
mouse monoclonal (A-10)
  • immunocytochemistry; human
  • western blot; human; 1:1000
Santa Cruz Biotechnology NFE2L2 antibody (Santa Cruz Biotechnology, sc-365949) was used in immunocytochemistry on human samples and in western blot on human samples at 1:1000. Biochim Biophys Acta (2014) ncbi
Invitrogen
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 3d
Invitrogen NFE2L2 antibody (ThermoFisher, PA5-67520) was used in western blot on mouse samples at 1:1000 (fig 3d). Redox Biol (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; loading ...; fig 1f
Invitrogen NFE2L2 antibody (Thermo Fisher, PA1-38312) was used in immunohistochemistry - paraffin section on human samples (fig 1f). Redox Biol (2020) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:200
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 7c
In order to identify NFE2L2/NRF2 as a regulator of autophagy gene expression and study its role in Alzheimer disease, Invitrogen NFE2L2 antibody (Thermo Fisher, PA13831) was used in immunohistochemistry on mouse samples at 1:200 and in immunohistochemistry - paraffin section on human samples at 1:200 (fig 7c). Autophagy (2016) ncbi
domestic rabbit polyclonal
In order to elucidate the molecular mechanism of fluoride-induced neurotoxicity using zebrafish, Invitrogen NFE2L2 antibody (Thermo, PA5-27882) was used . Environ Toxicol Pharmacol (2015) ncbi
domestic rabbit polyclonal
In order to prevent homocysteine-induced demethylation by administering acetyl-l-carnitine to human lens epithelial cells, Invitrogen NFE2L2 antibody (Thermo Fisher Scientific, PA5-27882) was used . Mol Med Rep (2015) ncbi
ProMab
mouse monoclonal (1A6G6)
  • western blot; human; 1:2000; fig 1c
ProMab NFE2L2 antibody (Promab Biotechnologies, 30597) was used in western blot on human samples at 1:2000 (fig 1c). Aging (Albany NY) (2020) ncbi
Novus Biologicals
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 2d
Novus Biologicals NFE2L2 antibody (Novus Biologicals, NBP1-32822) was used in western blot on mouse samples (fig 2d). Physiol Rep (2017) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D1Z9C)
  • western blot knockout validation; mouse; 1:2000; loading ...; fig s1c
Cell Signaling Technology NFE2L2 antibody (Cell Signaling, 12721) was used in western blot knockout validation on mouse samples at 1:2000 (fig s1c). Front Oncol (2021) ncbi
domestic rabbit monoclonal (D1Z9C)
  • western blot; mouse; 1:1000; loading ...; fig 4b
Cell Signaling Technology NFE2L2 antibody (CST, 12721) was used in western blot on mouse samples at 1:1000 (fig 4b). Front Pharmacol (2021) ncbi
domestic rabbit monoclonal (D1Z9C)
  • western blot knockout validation; human; loading ...; fig 1g
Cell Signaling Technology NFE2L2 antibody (Cell Signaling Technology, 12721 S) was used in western blot knockout validation on human samples (fig 1g). iScience (2021) ncbi
domestic rabbit monoclonal (D1Z9C)
  • immunohistochemistry; mouse; loading ...; fig 6b
Cell Signaling Technology NFE2L2 antibody (Cell Signaling Technology, 12721t) was used in immunohistochemistry on mouse samples (fig 6b). Oxid Med Cell Longev (2021) ncbi
domestic rabbit monoclonal (D1Z9C)
  • western blot; rat; 1:1000; loading ...; fig 6c
Cell Signaling Technology NFE2L2 antibody (Cell Signaling Technology, 12721) was used in western blot on rat samples at 1:1000 (fig 6c). Front Pharmacol (2021) ncbi
domestic rabbit monoclonal (D1Z9C)
  • immunocytochemistry; human; 1:1000; fig s10
  • western blot; human; 1:1000; fig s9e
Cell Signaling Technology NFE2L2 antibody (Cell Signaling Technology, 12721) was used in immunocytochemistry on human samples at 1:1000 (fig s10) and in western blot on human samples at 1:1000 (fig s9e). Nat Commun (2021) ncbi
domestic rabbit monoclonal (D1Z9C)
  • western blot; mouse; 1:1000; loading ...; fig 2d
Cell Signaling Technology NFE2L2 antibody (Cell Signaling Technology, 12721) was used in western blot on mouse samples at 1:1000 (fig 2d). Cell Death Discov (2021) ncbi
domestic rabbit monoclonal (D1Z9C)
  • western blot; human; fig 6a
Cell Signaling Technology NFE2L2 antibody (Cell Signaling Tech, 12721) was used in western blot on human samples (fig 6a). Aging (Albany NY) (2021) ncbi
domestic rabbit monoclonal (D1Z9C)
  • western blot; mouse; loading ...; fig 9c
Cell Signaling Technology NFE2L2 antibody (Cell Signaling Technology, 12721) was used in western blot on mouse samples (fig 9c). Redox Biol (2021) ncbi
domestic rabbit monoclonal (D1Z9C)
  • western blot; human; 1:200; fig 3j
Cell Signaling Technology NFE2L2 antibody (Cell Signaling Technology, 12721) was used in western blot on human samples at 1:200 (fig 3j). Mol Oncol (2021) ncbi
domestic rabbit monoclonal (D1Z9C)
  • western blot; human; loading ...
Cell Signaling Technology NFE2L2 antibody (Cell Signaling Technology, 12721) was used in western blot on human samples . Nat Commun (2020) ncbi
domestic rabbit monoclonal (D1Z9C)
  • western blot; mouse; loading ...; fig s5a
Cell Signaling Technology NFE2L2 antibody (CST, 12721S) was used in western blot on mouse samples (fig s5a). Theranostics (2020) ncbi
domestic rabbit monoclonal (D1Z9C)
  • western blot; rat; loading ...; fig 4a
Cell Signaling Technology NFE2L2 antibody (Cell Signaling, 12721S) was used in western blot on rat samples (fig 4a). Biol Sex Differ (2020) ncbi
domestic rabbit monoclonal (D1Z9C)
  • chromatin immunoprecipitation; mouse; loading ...; fig 3f
  • western blot; mouse; 1:1000; loading ...; fig 1j
Cell Signaling Technology NFE2L2 antibody (Cell Signaling, 12721) was used in chromatin immunoprecipitation on mouse samples (fig 3f) and in western blot on mouse samples at 1:1000 (fig 1j). Nat Commun (2020) ncbi
domestic rabbit monoclonal (D1Z9C)
  • western blot; mouse; 1:1000; loading ...; fig 3a
Cell Signaling Technology NFE2L2 antibody (Cell Signaling, DIZ9C) was used in western blot on mouse samples at 1:1000 (fig 3a). Aging (Albany NY) (2019) ncbi
domestic rabbit monoclonal (D1Z9C)
  • western blot; mouse; loading ...; fig 5c
Cell Signaling Technology NFE2L2 antibody (Cell Signaling, D1Z9C) was used in western blot on mouse samples (fig 5c). Redox Biol (2020) ncbi
domestic rabbit monoclonal (D1Z9C)
  • western blot; human; 1:200; loading ...; fig s2r
Cell Signaling Technology NFE2L2 antibody (Cell Signaling Technology, 12721) was used in western blot on human samples at 1:200 (fig s2r). Cell (2019) ncbi
domestic rabbit monoclonal (D1Z9C)
  • immunohistochemistry - paraffin section; human; 1:1000; loading ...; fig 2e
Cell Signaling Technology NFE2L2 antibody (Cell Signaling, 12721S) was used in immunohistochemistry - paraffin section on human samples at 1:1000 (fig 2e). Cell (2019) ncbi
domestic rabbit monoclonal (D1Z9C)
  • western blot; mouse; 1:1000; loading ...; fig 1b
Cell Signaling Technology NFE2L2 antibody (Cell Signaling, 12721) was used in western blot on mouse samples at 1:1000 (fig 1b). elife (2019) ncbi
domestic rabbit monoclonal (D1Z9C)
  • western blot; mouse; 1:1000; loading ...; fig 3i
Cell Signaling Technology NFE2L2 antibody (Cell Signaling, 12721) was used in western blot on mouse samples at 1:1000 (fig 3i). Biochem Biophys Res Commun (2018) ncbi
domestic rabbit monoclonal (D1Z9C)
  • western blot; mouse; loading ...; fig 1b
Cell Signaling Technology NFE2L2 antibody (cst, D1Z9C) was used in western blot on mouse samples (fig 1b). Biochem Biophys Res Commun (2018) ncbi
domestic rabbit monoclonal (D1Z9C)
  • western blot; human; 1:2000; loading ...; fig 6a
Cell Signaling Technology NFE2L2 antibody (Cell Signaling, 12721S) was used in western blot on human samples at 1:2000 (fig 6a). EMBO J (2018) ncbi
domestic rabbit monoclonal (D1Z9C)
  • western blot; human; loading ...; fig 2b
Cell Signaling Technology NFE2L2 antibody (Cell Signaling Technology, D1Z9C) was used in western blot on human samples (fig 2b). Oncogene (2018) ncbi
domestic rabbit monoclonal (D1Z9C)
  • western blot; mouse; loading ...; fig 3d
Cell Signaling Technology NFE2L2 antibody (Cell Signaling Technology, 12721) was used in western blot on mouse samples (fig 3d). J Exp Med (2017) ncbi
domestic rabbit monoclonal (D1Z9C)
  • western blot; human; loading ...; fig 3d
Cell Signaling Technology NFE2L2 antibody (Cell Signaling, 12721) was used in western blot on human samples (fig 3d). J Clin Invest (2017) ncbi
domestic rabbit monoclonal (D1Z9C)
  • western blot; human; loading ...; fig 4c
Cell Signaling Technology NFE2L2 antibody (Cell Signaling, 12721P) was used in western blot on human samples (fig 4c). J Biol Chem (2017) ncbi
domestic rabbit monoclonal (D1Z9C)
  • immunohistochemistry; human; 1:20
  • western blot; human; 1:200; loading ...; fig 1a
In order to find primary biliary cholangitis is associated with reduced nuclear factor (erythroid-derived 2)-like 2 expression, Cell Signaling Technology NFE2L2 antibody (Cell Signalling, 12721) was used in immunohistochemistry on human samples at 1:20 and in western blot on human samples at 1:200 (fig 1a). Sci Rep (2017) ncbi
domestic rabbit monoclonal (D1Z9C)
  • western blot; human; loading ...; fig s8j
Cell Signaling Technology NFE2L2 antibody (CST, 12721) was used in western blot on human samples (fig s8j). Nature (2017) ncbi
domestic rabbit monoclonal (D1Z9C)
  • western blot; human; loading ...; fig 6C
Cell Signaling Technology NFE2L2 antibody (Cell Signaling, 12721) was used in western blot on human samples (fig 6C). Oncotarget (2017) ncbi
domestic rabbit monoclonal (D1Z9C)
  • western blot; human; loading ...; fig 5a
Cell Signaling Technology NFE2L2 antibody (cell signalling, 12721) was used in western blot on human samples (fig 5a). Oncotarget (2017) ncbi
domestic rabbit monoclonal (D1Z9C)
  • western blot; human; loading ...; fig 7e
Cell Signaling Technology NFE2L2 antibody (Cell Signaling, 12721) was used in western blot on human samples (fig 7e). Int J Mol Sci (2016) ncbi
domestic rabbit monoclonal (D1Z9C)
  • western blot; human; 1:1000; loading ...; fig 2f
In order to identify and characterize an inhibitor of the COP9 signalosome, Cell Signaling Technology NFE2L2 antibody (Cell Signaling, 12721) was used in western blot on human samples at 1:1000 (fig 2f). Nat Commun (2016) ncbi
domestic rabbit monoclonal (D1Z9C)
  • western blot; human; loading ...; fig 2b
In order to research the oncogenic effect of NRF2 and its mechanism, Cell Signaling Technology NFE2L2 antibody (Cell Signaling, 12721) was used in western blot on human samples (fig 2b). Oncotarget (2016) ncbi
domestic rabbit monoclonal (D1Z9C)
  • western blot; human; loading ...; fig 2g
In order to determine the rotavirus NSP1-host protein interaction network, Cell Signaling Technology NFE2L2 antibody (CST, D1Z9C) was used in western blot on human samples (fig 2g). PLoS Pathog (2016) ncbi
domestic rabbit monoclonal (D1Z9C)
  • chromatin immunoprecipitation; mouse; 1:250; fig 4
Cell Signaling Technology NFE2L2 antibody (Cell Signaling technology, D1Z9C) was used in chromatin immunoprecipitation on mouse samples at 1:250 (fig 4). Nat Commun (2016) ncbi
domestic rabbit monoclonal (D1Z9C)
  • immunocytochemistry; rat; 1:250; fig 5
  • western blot; rat; fig 6
  • immunocytochemistry; mouse; 1:250; fig 5
  • western blot; mouse; fig 11
In order to decipher activation of TFEB and Nrf2 transcription factors and stimulation by Fisetin for autophagic degradation of phosphorylated tau, Cell Signaling Technology NFE2L2 antibody (Cell Signaling Technology, 12721) was used in immunocytochemistry on rat samples at 1:250 (fig 5), in western blot on rat samples (fig 6), in immunocytochemistry on mouse samples at 1:250 (fig 5) and in western blot on mouse samples (fig 11). Sci Rep (2016) ncbi
domestic rabbit monoclonal (D1Z9C)
  • western blot; mouse; 1:1000; loading ...; fig 5h
  • western blot; human; 1:1000; loading ...; fig 5h
Cell Signaling Technology NFE2L2 antibody (Cell Signaling, D1Z9C) was used in western blot on mouse samples at 1:1000 (fig 5h) and in western blot on human samples at 1:1000 (fig 5h). PLoS ONE (2016) ncbi
domestic rabbit monoclonal (D1Z9C)
  • immunoprecipitation; mouse; fig 8
  • western blot; mouse; 1:1000; fig 7
  • western blot; human; 1:1000; fig 7
In order to characterize the induction by activator protein 1 in colorectal cancer by glutathione S-transferase alpha 4, Cell Signaling Technology NFE2L2 antibody (Cell signaling, 12721) was used in immunoprecipitation on mouse samples (fig 8), in western blot on mouse samples at 1:1000 (fig 7) and in western blot on human samples at 1:1000 (fig 7). Oncogene (2016) ncbi
domestic rabbit monoclonal (D1Z9C)
  • ChIP-Seq; mouse; loading ...; fig 10a
In order to investigate the molecular mechanisms by which Nrf2 contributes to glucose homeostasis, Cell Signaling Technology NFE2L2 antibody (Cell Signaling, D1Z9C) was used in ChIP-Seq on mouse samples (fig 10a). Mol Cell Biol (2016) ncbi
domestic rabbit monoclonal (D1Z9C)
  • western blot; human; 1:500; fig 3, 4
Cell Signaling Technology NFE2L2 antibody (Cell Signaling, 12721) was used in western blot on human samples at 1:500 (fig 3, 4). Mol Med Rep (2016) ncbi
domestic rabbit monoclonal (D1Z9C)
  • western blot; human; loading ...; fig 8a
In order to study triterpenoid RTA 408, human retinal pigment epithelial cells, and H2O2-induced cell injury via NF-E2-related factor 2, Cell Signaling Technology NFE2L2 antibody (Cell Signaling, 12721) was used in western blot on human samples (fig 8a). Redox Biol (2016) ncbi
domestic rabbit monoclonal (D1Z9C)
  • immunohistochemistry; human; loading ...; fig 4a
  • western blot; human; loading ...; fig 4b
Cell Signaling Technology NFE2L2 antibody (Cell Signaling Technologies, 12721) was used in immunohistochemistry on human samples (fig 4a) and in western blot on human samples (fig 4b). Free Radic Biol Med (2016) ncbi
domestic rabbit monoclonal (D1Z9C)
  • chromatin immunoprecipitation; human; fig 10
Cell Signaling Technology NFE2L2 antibody (Cell signaling, D1Z9C-XP) was used in chromatin immunoprecipitation on human samples (fig 10). Mol Cell Biol (2016) ncbi
domestic rabbit monoclonal (D1Z9C)
  • western blot; mouse; loading ...; fig 2f
Cell Signaling Technology NFE2L2 antibody (Cell Signaling, D1Z9C) was used in western blot on mouse samples (fig 2f). Mol Cell Proteomics (2016) ncbi
domestic rabbit monoclonal (D1Z9C)
  • western blot knockout validation; mouse; 1:500; fig 2
Cell Signaling Technology NFE2L2 antibody (Cell Signaling, D1Z9C) was used in western blot knockout validation on mouse samples at 1:500 (fig 2). Proc Natl Acad Sci U S A (2014) ncbi
Articles Reviewed
  1. Chen F, Xiao M, Feng J, Wufur R, Liu K, Hu S, et al. Different Inhibition of Nrf2 by Two Keap1 Isoforms α and β to Shape Malignant Behaviour of Human Hepatocellular Carcinoma. Int J Mol Sci. 2022;23: pubmed publisher
  2. Stancic A, Velickovic K, Markelic M, Grigorov I, Saksida T, Savić N, et al. Involvement of Ferroptosis in Diabetes-Induced Liver Pathology. Int J Mol Sci. 2022;23: pubmed publisher
  3. Wrublewsky S, Glas J, Carlein C, Nalbach L, Hoffmann M, Pack M, et al. The loss of pancreatic islet NADPH oxidase (NOX)2 improves islet transplantation. Redox Biol. 2022;55:102419 pubmed publisher
  4. He S, Gao Q, Wu X, Shi J, Zhang Y, Yang J, et al. NAD+ ameliorates endotoxin-induced acute kidney injury in a sirtuin1-dependent manner via GSK-3β/Nrf2 signalling pathway. J Cell Mol Med. 2022;26:1979-1993 pubmed publisher
  5. Kumar B, Adebayo A, Prasad M, Capitano M, Wang R, Bhat Nakshatri P, et al. Tumor collection/processing under physioxia uncovers highly relevant signaling networks and drug sensitivity. Sci Adv. 2022;8:eabh3375 pubmed publisher
  6. Zhang C, Zhao M, Wang B, Su Z, Guo B, Qin L, et al. The Nrf2-NLRP3-caspase-1 axis mediates the neuroprotective effects of Celastrol in Parkinson's disease. Redox Biol. 2021;47:102134 pubmed publisher
  7. Cui M, Atmanli A, Morales M, Tan W, Chen K, Xiao X, et al. Nrf1 promotes heart regeneration and repair by regulating proteostasis and redox balance. Nat Commun. 2021;12:5270 pubmed publisher
  8. Rossino M, Amato R, Amadio M, Rosini M, Basagni F, Cammalleri M, et al. A Nature-Inspired Nrf2 Activator Protects Retinal Explants from Oxidative Stress and Neurodegeneration. Antioxidants (Basel). 2021;10: pubmed publisher
  9. Kang C, Song C, Kim N, Nam R, Choi S, Yu J, et al. The Enhanced Inhibitory Effect of Estrogen on PD-L1 Expression Following Nrf2 Deficiency in the AOM/DSS Model of Colitis-Associated Cancer. Front Oncol. 2021;11:679324 pubmed publisher
  10. Hou K, Shen J, Yan J, Zhai C, Zhang J, Pan J, et al. Loss of TRIM21 alleviates cardiotoxicity by suppressing ferroptosis induced by the chemotherapeutic agent doxorubicin. EBioMedicine. 2021;69:103456 pubmed publisher
  11. Wang L, Lavier J, Hua W, Wang Y, Gong L, Wei H, et al. High-Intensity Interval Training and Moderate-Intensity Continuous Training Attenuate Oxidative Damage and Promote Myokine Response in the Skeletal Muscle of ApoE KO Mice on High-Fat Diet. Antioxidants (Basel). 2021;10: pubmed publisher
  12. Teixeira V, Mohamed I, Lavoie J. Neonatal Vitamin C and Cysteine Deficiencies Program Adult Hepatic Glutathione and Specific Activities of Glucokinase, Phosphofructokinase, and Acetyl-CoA Carboxylase in Guinea Pigs' Livers. Antioxidants (Basel). 2021;10: pubmed publisher
  13. Cores A, Abril S, Michalska P, Duarte P, Olives A, Martín M, et al. Bisavenathramide Analogues as Nrf2 Inductors and Neuroprotectors in In Vitro Models of Oxidative Stress and Hyperphosphorylation. Antioxidants (Basel). 2021;10: pubmed publisher
  14. Li S, Jin H, Sun G, Zhang C, Wang J, Xu H, et al. Dietary Inorganic Nitrate Protects Hepatic Ischemia-Reperfusion Injury Through NRF2-Mediated Antioxidative Stress. Front Pharmacol. 2021;12:634115 pubmed publisher
  15. Koppula P, Olszewski K, Zhang Y, Kondiparthi L, Liu X, Lei G, et al. KEAP1 deficiency drives glucose dependency and sensitizes lung cancer cells and tumors to GLUT inhibition. iScience. 2021;24:102649 pubmed publisher
  16. Delaidelli A, Richner M, Jiang L, van der Laan A, Bergholdt Jul Christiansen I, Ferreira N, et al. α-Synuclein pathology in Parkinson disease activates homeostatic NRF2 anti-oxidant response. Acta Neuropathol Commun. 2021;9:105 pubmed publisher
  17. Lee S, Kim J, Choi Y, Gong J, Park S, Douangdeuane B, et al. Therapeutic Effects of Dipterocarpus tuberculatus with High Antioxidative Activity Against UV-Induced Photoaging of NHDF Cells and Nude Mice. Antioxidants (Basel). 2021;10: pubmed publisher
  18. Choi E, Jeong J, Jang H, Ahn Y, Kim K, An H, et al. Skeletal Lipocalin-2 Is Associated with Iron-Related Oxidative Stress in ob/ob Mice with Sarcopenia. Antioxidants (Basel). 2021;10: pubmed publisher
  19. Li S, Lei Z, Zhao M, Hou Y, Wang D, Xu X, et al. Propofol Inhibits Ischemia/Reperfusion-Induced Cardiotoxicity Through the Protein Kinase C/Nuclear Factor Erythroid 2-Related Factor Pathway. Front Pharmacol. 2021;12:655726 pubmed publisher
  20. Su Y, Wang Y, Liu M, Chen H. Hydrogen sulfide attenuates renal I/R‑induced activation of the inflammatory response and apoptosis via regulating Nrf2‑mediated NLRP3 signaling pathway inhibition. Mol Med Rep. 2021;24: pubmed publisher
  21. Shang L, Ren H, Wang S, Liu H, Hu A, Gou P, et al. SS-31 Protects Liver from Ischemia-Reperfusion Injury via Modulating Macrophage Polarization. Oxid Med Cell Longev. 2021;2021:6662156 pubmed publisher
  22. Hou M, Zhang Y, Zhou X, Liu T, Yang H, Chen X, et al. Kartogenin prevents cartilage degradation and alleviates osteoarthritis progression in mice via the miR-146a/NRF2 axis. Cell Death Dis. 2021;12:483 pubmed publisher
  23. Hu J, Wang J, Li C, Shang Y. Fructose-1,6-bisphosphatase aggravates oxidative stress-induced apoptosis in asthma by suppressing the Nrf2 pathway. J Cell Mol Med. 2021;25:5001-5014 pubmed publisher
  24. Park G, Lee J, Han H, An H, Jin Z, Jeong E, et al. Ablation of dynamin-related protein 1 promotes diabetes-induced synaptic injury in the hippocampus. Cell Death Dis. 2021;12:445 pubmed publisher
  25. Wang Q, Bin C, Xue Q, Gao Q, Huang A, Wang K, et al. GSTZ1 sensitizes hepatocellular carcinoma cells to sorafenib-induced ferroptosis via inhibition of NRF2/GPX4 axis. Cell Death Dis. 2021;12:426 pubmed publisher
  26. Zhang X, Yu K, Ma L, Qian Z, Tian X, Miao Y, et al. Endogenous glutamate determines ferroptosis sensitivity via ADCY10-dependent YAP suppression in lung adenocarcinoma. Theranostics. 2021;11:5650-5674 pubmed publisher
  27. Wang Z, Zhang X, Tian X, Yang Y, Ma L, Wang J, et al. CREB stimulates GPX4 transcription to inhibit ferroptosis in lung adenocarcinoma. Oncol Rep. 2021;45: pubmed publisher
  28. Zhou F, Zou X, Zhang J, Wang Z, Yang Y, Wang D. Jian-Pi-Yi-Shen Formula Ameliorates Oxidative Stress, Inflammation, and Apoptosis by Activating the Nrf2 Signaling in 5/6 Nephrectomized Rats. Front Pharmacol. 2021;12:630210 pubmed publisher
  29. Li Q, Xu Q, Tan J, Hu L, Ge C, Xu M. Carminic acid supplementation protects against fructose-induced kidney injury mainly through suppressing inflammation and oxidative stress via improving Nrf-2 signaling. Aging (Albany NY). 2021;13:10326-10353 pubmed publisher
  30. Goldfarb A, Freeman K, Sahu R, Elagib K, Holy M, Arneja A, et al. Iron control of erythroid microtubule cytoskeleton as a potential target in treatment of iron-restricted anemia. Nat Commun. 2021;12:1645 pubmed publisher
  31. Xu J, Ma L, Fu P. Eriocitrin attenuates ischemia reperfusion-induced oxidative stress and inflammation in rats with acute kidney injury by regulating the dual-specificity phosphatase 14 (DUSP14)-mediated Nrf2 and nuclear factor-κB (NF-κB) pathways. Ann Transl Med. 2021;9:350 pubmed publisher
  32. Zhang J, Zhang J, Ni H, Wang Y, Katwal G, Zhao Y, et al. Downregulation of XBP1 protects kidney against ischemia-reperfusion injury via suppressing HRD1-mediated NRF2 ubiquitylation. Cell Death Discov. 2021;7:44 pubmed publisher
  33. Cheng Y, Liu M, Tang H, Chen B, Yang G, Zhao W, et al. iTRAQ-Based Quantitative Proteomics Indicated Nrf2/OPTN-Mediated Mitophagy Inhibits NLRP3 Inflammasome Activation after Intracerebral Hemorrhage. Oxid Med Cell Longev. 2021;2021:6630281 pubmed publisher
  34. Naguib S, Backstrom J, Gil M, Calkins D, Rex T. Retinal oxidative stress activates the NRF2/ARE pathway: An early endogenous protective response to ocular hypertension. Redox Biol. 2021;42:101883 pubmed publisher
  35. Ryan B, Bengoa Vergniory N, Williamson M, Kirkiz E, Roberts R, Corda G, et al. REST protects dopaminergic neurons from mitochondrial and α-synuclein oligomer pathology in an alpha synuclein overexpressing BAC-transgenic mouse model. J Neurosci. 2021;: pubmed publisher
  36. Huang D, Dai C, Li S, Li X. Obacunone protects retinal pigment epithelium cells from ultra-violet radiation-induced oxidative injury. Aging (Albany NY). 2021;13:11010-11025 pubmed publisher
  37. Wang F, Zhang Y, Shen J, Yang B, Dai W, Yan J, et al. The Ubiquitin E3 Ligase TRIM21 Promotes Hepatocarcinogenesis by Suppressing the p62-Keap1-Nrf2 Antioxidant Pathway. Cell Mol Gastroenterol Hepatol. 2021;11:1369-1385 pubmed publisher
  38. Li S, Zhu Z, Xue M, Pan X, Tong G, Yi X, et al. The protective effects of fibroblast growth factor 10 against hepatic ischemia-reperfusion injury in mice. Redox Biol. 2021;40:101859 pubmed publisher
  39. Stojakovic A, Trushin S, Sheu A, Khalili L, Chang S, Li X, et al. Partial inhibition of mitochondrial complex I ameliorates Alzheimer's disease pathology and cognition in APP/PS1 female mice. Commun Biol. 2021;4:61 pubmed publisher
  40. Mota M, Metge B, Hinshaw D, Alsheikh H, Chen D, Samant R, et al. Merlin deficiency alters the redox management program in breast cancer. Mol Oncol. 2021;15:942-956 pubmed publisher
  41. Guo C, Sileikaite I, Davies M, Hawkins C. Myeloperoxidase Modulates Hydrogen Peroxide Mediated Cellular Damage in Murine Macrophages. Antioxidants (Basel). 2020;9: pubmed publisher
  42. Brockway S, Wang G, Jackson J, Amici D, Takagishi S, Clutter M, et al. Quantitative and multiplexed chemical-genetic phenotyping in mammalian cells with QMAP-Seq. Nat Commun. 2020;11:5722 pubmed publisher
  43. Chung L, Liu S, Huang S, Salter D, Lee H, Hsu Y. High phosphate induces skeletal muscle atrophy and suppresses myogenic differentiation by increasing oxidative stress and activating Nrf2 signaling. Aging (Albany NY). 2020;12:21446-21468 pubmed publisher
  44. Cai L, Jin X, Zhang J, Li L, Zhao J. Metformin suppresses Nrf2-mediated chemoresistance in hepatocellular carcinoma cells by increasing glycolysis. Aging (Albany NY). 2020;12:17582-17600 pubmed publisher
  45. Song H, Xu T, Feng X, Lai Y, Yang Y, Zheng H, et al. Itaconate prevents abdominal aortic aneurysm formation through inhibiting inflammation via activation of Nrf2. EBioMedicine. 2020;57:102832 pubmed publisher
  46. Busceti C, Cotugno M, Bianchi F, Forte M, Stanzione R, Marchitti S, et al. Brain Overexpression of Uncoupling Protein-2 (UCP2) Delays Renal Damage and Stroke Occurrence in Stroke-Prone Spontaneously Hypertensive Rats. Int J Mol Sci. 2020;21: pubmed publisher
  47. Kong Y, Xu S. Juglanin administration protects skin against UVB‑induced injury by reducing Nrf2‑dependent ROS generation. Int J Mol Med. 2020;46:67-82 pubmed publisher
  48. Sun K, Li Y, Meliton A, Woods P, Kimmig L, Cetin Atalay R, et al. Endogenous itaconate is not required for particulate matter-induced NRF2 expression or inflammatory response. elife. 2020;9: pubmed publisher
  49. Li X, Wu Y, Zhao J, Wang H, Tan J, Yang M, et al. Distinct cardiac energy metabolism and oxidative stress adaptations between obese and non-obese type 2 diabetes mellitus. Theranostics. 2020;10:2675-2695 pubmed publisher
  50. Rafikova O, James J, Eccles C, Kurdyukov S, Niihori M, Varghese M, et al. Early progression of pulmonary hypertension in the monocrotaline model in males is associated with increased lung permeability. Biol Sex Differ. 2020;11:11 pubmed publisher
  51. Pinterić M, Podgorski I, Hadžija M, Bujak I, Dekanic A, Bagarić R, et al. Role of Sirt3 in Differential Sex-Related Responses to a High-Fat Diet in Mice. Antioxidants (Basel). 2020;9: pubmed publisher
  52. Wei Y, Lu M, Mei M, Wang H, Han Z, Chen M, et al. Pyridoxine induces glutathione synthesis via PKM2-mediated Nrf2 transactivation and confers neuroprotection. Nat Commun. 2020;11:941 pubmed publisher
  53. Yu J, Wang W, Matei N, Li X, Pang J, Mo J, et al. Ezetimibe Attenuates Oxidative Stress and Neuroinflammation via the AMPK/Nrf2/TXNIP Pathway after MCAO in Rats. Oxid Med Cell Longev. 2020;2020:4717258 pubmed publisher
  54. Lin C, Lin W, Cho R, Yang C, Yeh Y, Hsiao L, et al. Induction of HO-1 by Mevastatin Mediated via a Nox/ROS-Dependent c-Src/PDGFRα/PI3K/Akt/Nrf2/ARE Cascade Suppresses TNF-α-Induced Lung Inflammation. J Clin Med. 2020;9: pubmed publisher
  55. Molagoda I, Lee K, Choi Y, Kim G. Anthocyanins from Hibiscus syriacus L. Inhibit Oxidative Stress-Mediated Apoptosis by Activating the Nrf2/HO-1 Signaling Pathway. Antioxidants (Basel). 2020;9: pubmed publisher
  56. Escoll M, Lastra D, Pajares M, Robledinos Antón N, Rojo A, Fernández Ginés R, et al. Transcription factor NRF2 uses the Hippo pathway effector TAZ to induce tumorigenesis in glioblastomas. Redox Biol. 2020;30:101425 pubmed publisher
  57. Sarker M, Lee J, Lee D, Chun K, Jun H. Attenuation of diabetic kidney injury in DPP4-deficient rats; role of GLP-1 on the suppression of AGE formation by inducing glyoxalase 1. Aging (Albany NY). 2020;12:593-610 pubmed publisher
  58. Yuan Z, Yang L, Zhang X, Ji P, Hua Y, Wei Y. Huang-Lian-Jie-Du Decoction Ameliorates Acute Ulcerative Colitis in Mice via Regulating NF-κB and Nrf2 Signaling Pathways and Enhancing Intestinal Barrier Function. Front Pharmacol. 2019;10:1354 pubmed publisher
  59. Griñan Ferré C, Marsal García L, Bellver Sanchis A, Kondengaden S, Turga R, Vazquez S, et al. Pharmacological inhibition of G9a/GLP restores cognition and reduces oxidative stress, neuroinflammation and β-Amyloid plaques in an early-onset Alzheimer's disease mouse model. Aging (Albany NY). 2019;11:11591-11608 pubmed publisher
  60. Tracey N, Creedon H, Kemp A, Culley J, Muir M, Klinowska T, et al. HO-1 drives autophagy as a mechanism of resistance against HER2-targeted therapies. Breast Cancer Res Treat. 2020;179:543-555 pubmed publisher
  61. Berry A, Marconi M, Musillo C, Chiarotti F, Bellisario V, Matarrese P, et al. Trehalose administration in C57BL/6N old mice affects healthspan improving motor learning and brain anti-oxidant defences in a sex-dependent fashion: a pilot study. Exp Gerontol. 2020;129:110755 pubmed publisher
  62. Casares L, Garcia V, Garrido Rodríguez M, Millán E, Collado J, Garcia Martin A, et al. Cannabidiol induces antioxidant pathways in keratinocytes by targeting BACH1. Redox Biol. 2020;28:101321 pubmed publisher
  63. Choi W, Kim H, Kim M, Cinar R, Yi H, Eun H, et al. Glutamate Signaling in Hepatic Stellate Cells Drives Alcoholic Steatosis. Cell Metab. 2019;30:877-889.e7 pubmed publisher
  64. Wiel C, Le Gal K, Ibrahim M, Jahangir C, Kashif M, Yao H, et al. BACH1 Stabilization by Antioxidants Stimulates Lung Cancer Metastasis. Cell. 2019;: pubmed publisher
  65. Lignitto L, LeBoeuf S, Homer H, Jiang S, Askenazi M, Karakousi T, et al. Nrf2 Activation Promotes Lung Cancer Metastasis by Inhibiting the Degradation of Bach1. Cell. 2019;: pubmed publisher
  66. Kang Y, Torrente L, Falzone A, Elkins C, Liu M, Asara J, et al. Cysteine dioxygenase 1 is a metabolic liability for non-small cell lung cancer. elife. 2019;8: pubmed publisher
  67. Basnet H, Tian L, Ganesh K, Huang Y, Macalinao D, Brogi E, et al. Flura-seq identifies organ-specific metabolic adaptations during early metastatic colonization. elife. 2019;8: pubmed publisher
  68. Zhu Y, Zhang Y, Huang X, Xie Y, Qu Y, Long H, et al. Z-Ligustilide protects vascular endothelial cells from oxidative stress and rescues high fat diet-induced atherosclerosis by activating multiple NRF2 downstream genes. Atherosclerosis. 2019;284:110-120 pubmed publisher
  69. Cao J, Poddar A, Magtanong L, Lumb J, Mileur T, Reid M, et al. A Genome-wide Haploid Genetic Screen Identifies Regulators of Glutathione Abundance and Ferroptosis Sensitivity. Cell Rep. 2019;26:1544-1556.e8 pubmed publisher
  70. Qiu L, Wang M, Hu S, Ru X, Ren Y, Zhang Z, et al. Oncogenic Activation of Nrf2, Though as a Master Antioxidant Transcription Factor, Liberated by Specific Knockout of the Full-Length Nrf1α that Acts as a Dominant Tumor Repressor. Cancers (Basel). 2018;10: pubmed publisher
  71. Li C, Liu Q, Xie L. Suppressing NLRP2 expression accelerates hepatic steatosis: A mechanism involving inflammation and oxidative stress. Biochem Biophys Res Commun. 2018;507:22-29 pubmed publisher
  72. Inouye S, Hatori Y, Kubo T, Saito S, Kitamura H, Akagi R. NRF2 and HSF1 coordinately regulate heme oxygenase-1 expression. Biochem Biophys Res Commun. 2018;506:7-11 pubmed publisher
  73. Gong F, Gu J, Wang H. Up regulated Tmbim1 activation promotes high fat diet (HFD)-induced cardiomyopathy by enhancement of inflammation and oxidative stress. Biochem Biophys Res Commun. 2018;504:797-804 pubmed publisher
  74. Jena K, Kolapalli S, Mehto S, Nath P, Das B, Sahoo P, et al. TRIM16 controls assembly and degradation of protein aggregates by modulating the p62-NRF2 axis and autophagy. EMBO J. 2018;37: pubmed publisher
  75. Zhu B, Tang L, Chen S, Yin C, Peng S, Li X, et al. Targeting the upstream transcriptional activator of PD-L1 as an alternative strategy in melanoma therapy. Oncogene. 2018;37:4941-4954 pubmed publisher
  76. Lv W, Deng B, Duan W, Li Y, Liu Y, Li Z, et al. Schwann Cell Plasticity is Regulated by a Weakened Intrinsic Antioxidant Defense System in Acute Peripheral Nerve Injury. Neuroscience. 2018;382:1-13 pubmed publisher
  77. Li Y, Lou C, Wang W. STIM1 deficiency protects the liver from ischemia/reperfusion injury in mice. Biochem Biophys Res Commun. 2018;496:422-428 pubmed publisher
  78. Niwa Kawakita M, Ferhi O, Soilihi H, Le Bras M, Lallemand Breitenbach V, de Thé H. PML is a ROS sensor activating p53 upon oxidative stress. J Exp Med. 2017;214:3197-3206 pubmed publisher
  79. Caino M, Seo J, Wang Y, Rivadeneira D, Gabrilovich D, Kim E, et al. Syntaphilin controls a mitochondrial rheostat for proliferation-motility decisions in cancer. J Clin Invest. 2017;127:3755-3769 pubmed publisher
  80. Jiang X, Bao Y, Liu H, Kou X, Zhang Z, Sun F, et al. VPS34 stimulation of p62 phosphorylation for cancer progression. Oncogene. 2017;36:6850-6862 pubmed publisher
  81. Skowron M, Niegisch G, Albrecht P, Van Koeveringe G, Romano A, Albers P, et al. Various Mechanisms Involve the Nuclear Factor (Erythroid-Derived 2)-Like (NRF2) to Achieve Cytoprotection in Long-Term Cisplatin-Treated Urothelial Carcinoma Cell Lines. Int J Mol Sci. 2017;18: pubmed publisher
  82. Perez Leal O, Barrero C, Merali S. Pharmacological stimulation of nuclear factor (erythroid-derived 2)-like 2 translation activates antioxidant responses. J Biol Chem. 2017;292:14108-14121 pubmed publisher
  83. Scott D, Hammill J, Min J, Rhee D, Connelly M, Sviderskiy V, et al. Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase. Nat Chem Biol. 2017;13:850-857 pubmed publisher
  84. Wasik U, Milkiewicz M, Kempińska Podhorodecka A, Milkiewicz P. Protection against oxidative stress mediated by the Nrf2/Keap1 axis is impaired in Primary Biliary Cholangitis. Sci Rep. 2017;7:44769 pubmed publisher
  85. Ghosh A, Abdo S, Zhao S, Wu C, Shi Y, Lo C, et al. Insulin Inhibits Nrf2 Gene Expression via Heterogeneous Nuclear Ribonucleoprotein F/K in Diabetic Mice. Endocrinology. 2017;158:903-919 pubmed publisher
  86. Chung E, Joiner H, Skelton T, Looten K, Manczak M, Reddy P. Maternal exercise upregulates mitochondrial gene expression and increases enzyme activity of fetal mouse hearts. Physiol Rep. 2017;5: pubmed publisher
  87. Li J, Yakushi T, Parlati F, MacKinnon A, Pérez C, Ma Y, et al. Capzimin is a potent and specific inhibitor of proteasome isopeptidase Rpn11. Nat Chem Biol. 2017;13:486-493 pubmed publisher
  88. Bao L, Wu J, Dodson M, Rojo de la Vega E, Ning Y, Zhang Z, et al. ABCF2, an Nrf2 target gene, contributes to cisplatin resistance in ovarian cancer cells. Mol Carcinog. 2017;56:1543-1553 pubmed publisher
  89. Dey P, Baddour J, Muller F, Wu C, Wang H, Liao W, et al. Genomic deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer. Nature. 2017;542:119-123 pubmed publisher
  90. Cheng L, Li K, Yi N, Li X, Wang F, Xue B, et al. miRNA-141 attenuates UV-induced oxidative stress via activating Keap1-Nrf2 signaling in human retinal pigment epithelium cells and retinal ganglion cells. Oncotarget. 2017;8:13186-13194 pubmed publisher
  91. Ugun Klusek A, Tatham M, Elkharaz J, Constantin Teodosiu D, Lawler K, Mohamed H, et al. Continued 26S proteasome dysfunction in mouse brain cortical neurons impairs autophagy and the Keap1-Nrf2 oxidative defence pathway. Cell Death Dis. 2017;8:e2531 pubmed publisher
  92. Wang M, Li G, Yang Z, Wang L, Zhang L, Wang T, et al. Uncoupling protein 2 downregulation by hypoxia through repression of peroxisome proliferator-activated receptor γ promotes chemoresistance of non-small cell lung cancer. Oncotarget. 2017;8:8083-8094 pubmed publisher
  93. Duan W, Chen J, Wu Y, Zhang Y, Xu Y. Protective effect of higenamine ameliorates collagen-induced arthritis through heme oxygenase-1 and PI3K/Akt/Nrf-2 signaling pathways. Exp Ther Med. 2016;12:3107-3112 pubmed
  94. Liu X, Xavier C, Jann J, Wu H. Salvianolic Acid B (Sal B) Protects Retinal Pigment Epithelial Cells from Oxidative Stress-Induced Cell Death by Activating Glutaredoxin 1 (Grx1). Int J Mol Sci. 2016;17: pubmed
  95. Zhou J, Ge L, Jia C, Zheng X, Cui H, Zong R, et al. ROS-mediated Different Homeostasis of Murine Corneal Epithelial Progenitor Cell Line under Oxidative Stress. Sci Rep. 2016;6:36481 pubmed publisher
  96. Schlierf A, Altmann E, Quancard J, Jefferson A, Assenberg R, Renatus M, et al. Targeted inhibition of the COP9 signalosome for treatment of cancer. Nat Commun. 2016;7:13166 pubmed publisher
  97. Arora R, Sawney S, Saini V, Steffi C, Tiwari M, Saluja D. Esculetin induces antiproliferative and apoptotic response in pancreatic cancer cells by directly binding to KEAP1. Mol Cancer. 2016;15:64 pubmed
  98. Zhang C, Wang H, Bao Q, Wang L, Guo T, Chen W, et al. NRF2 promotes breast cancer cell proliferation and metastasis by increasing RhoA/ROCK pathway signal transduction. Oncotarget. 2016;7:73593-73606 pubmed publisher
  99. Ding S, Mooney N, Li B, Kelly M, Feng N, Loktev A, et al. Comparative Proteomics Reveals Strain-Specific β-TrCP Degradation via Rotavirus NSP1 Hijacking a Host Cullin-3-Rbx1 Complex. PLoS Pathog. 2016;12:e1005929 pubmed publisher
  100. Tian Y, Wu K, Liu Q, Han N, Zhang L, Chu Q, et al. Modification of platinum sensitivity by KEAP1/NRF2 signals in non-small cell lung cancer. J Hematol Oncol. 2016;9:83 pubmed publisher
  101. Tanaka G, Inoue K, Shimizu T, Akimoto K, Kubota K. Dual pharmacological inhibition of glutathione and thioredoxin systems synergizes to kill colorectal carcinoma stem cells. Cancer Med. 2016;5:2544-57 pubmed publisher
  102. Pajares M, Jiménez Moreno N, García Yagüe A, Escoll M, De Ceballos M, Van Leuven F, et al. Transcription factor NFE2L2/NRF2 is a regulator of macroautophagy genes. Autophagy. 2016;12:1902-1916 pubmed
  103. Walerych D, Lisek K, Sommaggio R, Piazza S, Ciani Y, Dalla E, et al. Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer. Nat Cell Biol. 2016;18:897-909 pubmed publisher
  104. Yang D, Yuan Q, Balakrishnan A, Bantel H, Klusmann J, Manns M, et al. MicroRNA-125b-5p mimic inhibits acute liver failure. Nat Commun. 2016;7:11916 pubmed publisher
  105. Han B, Poppinga W, Zuo H, Zuidhof A, Bos I, Smit M, et al. The novel compound Sul-121 inhibits airway inflammation and hyperresponsiveness in experimental models of chronic obstructive pulmonary disease. Sci Rep. 2016;6:26928 pubmed publisher
  106. Shi X, Li Y, Hu J, Yu B. Tert-butylhydroquinone attenuates the ethanol-induced apoptosis of and activates the Nrf2 antioxidant defense pathway in H9c2 cardiomyocytes. Int J Mol Med. 2016;38:123-30 pubmed publisher
  107. Kobayashi E, Suzuki T, Funayama R, Nagashima T, Hayashi M, Sekine H, et al. Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription. Nat Commun. 2016;7:11624 pubmed publisher
  108. Moshfegh C, Aires L, Kisielow M, Vogel V. A gonogenic stimulated transition of mouse embryonic stem cells with enhanced control of diverse differentiation pathways. Sci Rep. 2016;6:25104 pubmed publisher
  109. Kim S, Choi K, Cho S, Yun S, Jeon J, Koh Y, et al. Fisetin stimulates autophagic degradation of phosphorylated tau via the activation of TFEB and Nrf2 transcription factors. Sci Rep. 2016;6:24933 pubmed publisher
  110. Zanotto Filho A, Dashnamoorthy R, Loranc E, de Souza L, Moreira J, Suresh U, et al. Combined Gene Expression and RNAi Screening to Identify Alkylation Damage Survival Pathways from Fly to Human. PLoS ONE. 2016;11:e0153970 pubmed publisher
  111. Yang Y, Huycke M, Herman T, Wang X. Glutathione S-transferase alpha 4 induction by activator protein 1 in colorectal cancer. Oncogene. 2016;35:5795-5806 pubmed publisher
  112. Uruno A, Yagishita Y, Katsuoka F, Kitajima Y, Nunomiya A, Nagatomi R, et al. Nrf2-Mediated Regulation of Skeletal Muscle Glycogen Metabolism. Mol Cell Biol. 2016;36:1655-72 pubmed publisher
  113. Yang W, Yang Y, Yang J, Liang M, Song J. Treatment with bone marrow mesenchymal stem cells combined with plumbagin alleviates spinal cord injury by affecting oxidative stress, inflammation, apoptotis and the activation of the Nrf2 pathway. Int J Mol Med. 2016;37:1075-82 pubmed publisher
  114. Sakurai T, Isogaya K, Sakai S, Morikawa M, Morishita Y, Ehata S, et al. RNA-binding motif protein 47 inhibits Nrf2 activity to suppress tumor growth in lung adenocarcinoma. Oncogene. 2016;35:5000-9 pubmed publisher
  115. Tu G, Zhang Y, Wei W, Li L, Zhang Y, Yang J, et al. Allicin attenuates Hâ‚‚Oâ‚‚-induced cytotoxicity in retinal pigmented epithelial cells by regulating the levels of reactive oxygen species. Mol Med Rep. 2016;13:2320-6 pubmed publisher
  116. Liu X, Ward K, Xavier C, Jann J, Clark A, Pang I, et al. The novel triterpenoid RTA 408 protects human retinal pigment epithelial cells against H2O2-induced cell injury via NF-E2-related factor 2 (Nrf2) activation. Redox Biol. 2016;8:98-109 pubmed publisher
  117. Khalil H, Langdon S, Kankia I, Bown J, Deeni Y. NRF2 Regulates HER2 and HER3 Signaling Pathway to Modulate Sensitivity to Targeted Immunotherapies. Oxid Med Cell Longev. 2016;2016:4148791 pubmed publisher
  118. Pan H, Guan D, Liu X, Li J, Wang L, Wu J, et al. SIRT6 safeguards human mesenchymal stem cells from oxidative stress by coactivating NRF2. Cell Res. 2016;26:190-205 pubmed publisher
  119. Vartanian S, Ma T, Lee J, Haverty P, Kirkpatrick D, Yu K, et al. Application of Mass Spectrometry Profiling to Establish Brusatol as an Inhibitor of Global Protein Synthesis. Mol Cell Proteomics. 2016;15:1220-31 pubmed publisher
  120. Yamano S, Gi M, Tago Y, Doi K, Okada S, Hirayama Y, et al. Role of deltaNp63(pos)CD44v(pos) cells in the development of N-nitroso-tris-chloroethylurea-induced peripheral-type mouse lung squamous cell carcinomas. Cancer Sci. 2016;107:123-32 pubmed publisher
  121. Orthwein A, Noordermeer S, Wilson M, Landry S, Enchev R, Sherker A, et al. A mechanism for the suppression of homologous recombination in G1 cells. Nature. 2015;528:422-6 pubmed publisher
  122. Pettersen K, Monsen V, Hakvåg Pettersen C, Overland H, Pettersen G, Samdal H, et al. DHA-induced stress response in human colon cancer cells - Focus on oxidative stress and autophagy. Free Radic Biol Med. 2016;90:158-72 pubmed publisher
  123. Sekine H, Okazaki K, Ota N, Shima H, Katoh Y, Suzuki N, et al. The Mediator Subunit MED16 Transduces NRF2-Activating Signals into Antioxidant Gene Expression. Mol Cell Biol. 2016;36:407-20 pubmed publisher
  124. Ivankovic D, Chau K, Schapira A, Gegg M. Mitochondrial and lysosomal biogenesis are activated following PINK1/parkin-mediated mitophagy. J Neurochem. 2016;136:388-402 pubmed publisher
  125. Abu Alainin W, Gana T, Liloglou T, Olayanju A, Barrera L, Ferguson R, et al. UHRF1 regulation of the Keap1-Nrf2 pathway in pancreatic cancer contributes to oncogenesis. J Pathol. 2016;238:423-33 pubmed publisher
  126. Pehar M, Ball L, Sharma D, Harlan B, Comte Walters S, Neely B, et al. Changes in Protein Expression and Lysine Acetylation Induced by Decreased Glutathione Levels in Astrocytes. Mol Cell Proteomics. 2016;15:493-505 pubmed publisher
  127. Konzack A, Jakupovic M, Kubaichuk K, Görlach A, Dombrowski F, Miinalainen I, et al. Mitochondrial Dysfunction Due to Lack of Manganese Superoxide Dismutase Promotes Hepatocarcinogenesis. Antioxid Redox Signal. 2015;23:1059-75 pubmed publisher
  128. Min S, Yan M, Kim S, Ravikumar S, Kwon S, Vanarsa K, et al. Green Tea Epigallocatechin-3-Gallate Suppresses Autoimmune Arthritis Through Indoleamine-2,3-Dioxygenase Expressing Dendritic Cells and the Nuclear Factor, Erythroid 2-Like 2 Antioxidant Pathway. J Inflamm (Lond). 2015;12:53 pubmed publisher
  129. Mukhopadhyay D, Priya P, Chattopadhyay A. Sodium fluoride affects zebrafish behaviour and alters mRNA expressions of biomarker genes in the brain: Role of Nrf2/Keap1. Environ Toxicol Pharmacol. 2015;40:352-9 pubmed publisher
  130. Licht Mayer S, Wimmer I, Traffehn S, Metz I, Brück W, Bauer J, et al. Cell type-specific Nrf2 expression in multiple sclerosis lesions. Acta Neuropathol. 2015;130:263-77 pubmed publisher
  131. Sachweh M, Stafford W, Drummond C, McCarthy A, Higgins M, Campbell J, et al. Redox effects and cytotoxic profiles of MJ25 and auranofin towards malignant melanoma cells. Oncotarget. 2015;6:16488-506 pubmed
  132. Bakkar N, Kousari A, Kovalik T, Li Y, Bowser R. RBM45 Modulates the Antioxidant Response in Amyotrophic Lateral Sclerosis through Interactions with KEAP1. Mol Cell Biol. 2015;35:2385-99 pubmed publisher
  133. Yang S, Yang X, Cao G. Acetyl-l-carnitine prevents homocysteine-induced suppression of Nrf2/Keap1 mediated antioxidation in human lens epithelial cells. Mol Med Rep. 2015;12:1145-50 pubmed publisher
  134. Kawasaki Y, Ishigami S, Arigami T, Uenosono Y, Yanagita S, Uchikado Y, et al. Clinicopathological significance of nuclear factor (erythroid-2)-related factor 2 (Nrf2) expression in gastric cancer. BMC Cancer. 2015;15:5 pubmed publisher
  135. Gong X, Yi J, Carmon K, Crumbley C, Xiong W, Thomas A, et al. Aberrant RSPO3-LGR4 signaling in Keap1-deficient lung adenocarcinomas promotes tumor aggressiveness. Oncogene. 2015;34:4692-701 pubmed publisher
  136. Ishaq M, Evans M, Ostrikov K. Atmospheric pressure gas plasma-induced colorectal cancer cell death is mediated by Nox2-ASK1 apoptosis pathways and oxidative stress is mitigated by Srx-Nrf2 anti-oxidant system. Biochim Biophys Acta. 2014;1843:2827-37 pubmed publisher
  137. Ribeiro M, Rosenstock T, Oliveira A, Oliveira C, Rego A. Insulin and IGF-1 improve mitochondrial function in a PI-3K/Akt-dependent manner and reduce mitochondrial generation of reactive oxygen species in Huntington's disease knock-in striatal cells. Free Radic Biol Med. 2014;74:129-44 pubmed publisher
  138. Buelna Chontal M, Guevara Chávez J, Silva Palacios A, Medina Campos O, Pedraza Chaverri J, Zazueta C. Nrf2-regulated antioxidant response is activated by protein kinase C in postconditioned rat hearts. Free Radic Biol Med. 2014;74:145-56 pubmed publisher
  139. Zhao C, Gillette D, Li X, Zhang Z, Wen H. Nuclear factor E2-related factor-2 (Nrf2) is required for NLRP3 and AIM2 inflammasome activation. J Biol Chem. 2014;289:17020-9 pubmed publisher
  140. Deighton R, Márkus N, Al Mubarak B, Bell K, Papadia S, Meakin P, et al. Nrf2 target genes can be controlled by neuronal activity in the absence of Nrf2 and astrocytes. Proc Natl Acad Sci U S A. 2014;111:E1818-20 pubmed publisher
  141. Ramyaa P, Krishnaswamy R, Padma V. Quercetin modulates OTA-induced oxidative stress and redox signalling in HepG2 cells - up regulation of Nrf2 expression and down regulation of NF-?B and COX-2. Biochim Biophys Acta. 2014;1840:681-92 pubmed publisher