This is a Validated Antibody Database (VAD) review about human NEK7, based on 6 published articles (read how Labome selects the articles), using NEK7 antibody in all methods. It is aimed to help Labome visitors find the most suited NEK7 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Abcam
domestic rabbit monoclonal (EPR4900)
  • western blot; mouse; loading ...; fig ex6a
Abcam NEK7 antibody (Abcam, ab133514) was used in western blot on mouse samples (fig ex6a). Nature (2019) ncbi
domestic rabbit monoclonal (EPR4900)
  • western blot; mouse; loading ...; fig 1e
Abcam NEK7 antibody (Abcam, ab133514) was used in western blot on mouse samples (fig 1e). Nat Commun (2017) ncbi
domestic rabbit monoclonal (EPR4900)
  • immunoprecipitation; human; 1:100; fig 1
  • western blot; human; fig 1
Abcam NEK7 antibody (Abcam, ab133514) was used in immunoprecipitation on human samples at 1:100 (fig 1) and in western blot on human samples (fig 1). Nature (2016) ncbi
Invitrogen
domestic rabbit monoclonal (H.691.4)
  • western blot; human; 1:1000
Invitrogen NEK7 antibody (Thermo Scientific, H.691.4) was used in western blot on human samples at 1:1000. Mol Cancer Res (2015) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (C34C3)
  • western blot; human; 1:1000; loading ...; fig 3
Cell Signaling Technology NEK7 antibody (Cell Signaling Technolog, 3057) was used in western blot on human samples at 1:1000 (fig 3). J Inflamm (Lond) (2018) ncbi
domestic rabbit monoclonal (C34C3)
  • western blot; dogs; 1:500; fig 5c
In order to assess the contribution of aPKC to epithelial cell transformation, Cell Signaling Technology NEK7 antibody (Cell Signaling Technology, 3057S) was used in western blot on dogs samples at 1:500 (fig 5c). Mol Biol Cell (2015) ncbi
Articles Reviewed
  1. Samir P, Kesavardhana S, Patmore D, Gingras S, Malireddi R, Karki R, et al. DDX3X acts as a live-or-die checkpoint in stressed cells by regulating NLRP3 inflammasome. Nature. 2019;573:590-594 pubmed publisher
  2. Ma Z, Sun H, Lv J, Guo L, Yang Q. Expression and clinical significance of the NEK7-NLRP3 inflammasome signaling pathway in patients with systemic lupus erythematosus. J Inflamm (Lond). 2018;15:16 pubmed publisher
  3. Li X, Thome S, Ma X, Amrute Nayak M, Finigan A, Kitt L, et al. MARK4 regulates NLRP3 positioning and inflammasome activation through a microtubule-dependent mechanism. Nat Commun. 2017;8:15986 pubmed publisher
  4. He Y, Zeng M, Yang D, Motro B, Núñez G. NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux. Nature. 2016;530:354-7 pubmed publisher
  5. Archibald A, Al Masri M, Liew Spilger A, McCaffrey L. Atypical protein kinase C induces cell transformation by disrupting Hippo/Yap signaling. Mol Biol Cell. 2015;26:3578-95 pubmed publisher
  6. Saloura V, Cho H, Kiyotani K, Alachkar H, Zuo Z, Nakakido M, et al. WHSC1 promotes oncogenesis through regulation of NIMA-related kinase-7 in squamous cell carcinoma of the head and neck. Mol Cancer Res. 2015;13:293-304 pubmed publisher