This is a Validated Antibody Database (VAD) review about human NECTIN2, based on 18 published articles (read how Labome selects the articles), using NECTIN2 antibody in all methods. It is aimed to help Labome visitors find the most suited NECTIN2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
NECTIN2 synonym: CD112; HVEB; PRR2; PVRL2; PVRR2

BioLegend
mouse monoclonal (TX31)
  • flow cytometry; human; loading ...; fig 1
BioLegend NECTIN2 antibody (Biolegend, TX31) was used in flow cytometry on human samples (fig 1). Oncogene (2018) ncbi
mouse monoclonal (TX31)
  • flow cytometry; human; loading ...
In order to show T cell immunoglobulin and ITIM domain expression increases over time despite early initiation of antiretroviral treatment, BioLegend NECTIN2 antibody (Biolegend, TX31) was used in flow cytometry on human samples . Sci Rep (2017) ncbi
mouse monoclonal (TX31)
  • flow cytometry; human; fig 3
BioLegend NECTIN2 antibody (Biolegend, TX31) was used in flow cytometry on human samples (fig 3). Oncoimmunology (2016) ncbi
mouse monoclonal (TX31)
  • flow cytometry; human
BioLegend NECTIN2 antibody (Biolegend, 337410) was used in flow cytometry on human samples . Cancer Lett (2015) ncbi
mouse monoclonal (TX31)
  • flow cytometry; human; fig 7
In order to investigate the dynamics and characteristics of natural killer cell types in the human ocular mucosal surface in situ during infection with group D human adenoviruses, BioLegend NECTIN2 antibody (Biolegend, TX31) was used in flow cytometry on human samples (fig 7). Mucosal Immunol (2016) ncbi
R&D Systems
mouse monoclonal (610603)
  • flow cytometry; human; loading ...; fig 1b
R&D Systems NECTIN2 antibody (R&D, 610603) was used in flow cytometry on human samples (fig 1b). BMC Immunol (2019) ncbi
mouse monoclonal (610603)
  • flow cytometry; human; loading ...; fig 6g
R&D Systems NECTIN2 antibody (R&D Systems, 610603) was used in flow cytometry on human samples (fig 6g). J Immunol (2018) ncbi
Santa Cruz Biotechnology
mouse monoclonal (R2.525)
  • flow cytometry; human; fig 3b
Santa Cruz Biotechnology NECTIN2 antibody (Santa Cruz, sc-32804) was used in flow cytometry on human samples (fig 3b). Gene Ther (2016) ncbi
mouse monoclonal (R2.525)
  • flow cytometry; human; fig 3
  • immunocytochemistry; human; fig 3
  • western blot; human; fig 1
In order to characterize the influence on NK cell cytotoxicity by differential expression of ligands for DNAM-1 and NKG2D receptors by epithelial ovarian cancer-derived exosomes, Santa Cruz Biotechnology NECTIN2 antibody (Santa Cruz Biotechnology, R2.525) was used in flow cytometry on human samples (fig 3), in immunocytochemistry on human samples (fig 3) and in western blot on human samples (fig 1). Tumour Biol (2016) ncbi
brown rat monoclonal (6A606)
  • flow cytometry; mouse; fig 2
Santa Cruz Biotechnology NECTIN2 antibody (Santa Cruz, 6A606) was used in flow cytometry on mouse samples (fig 2). Cancer Immunol Immunother (2015) ncbi
mouse monoclonal (R2.525)
  • flow cytometry; human
Santa Cruz Biotechnology NECTIN2 antibody (Santa Cruz Biotechnology, sc-32804) was used in flow cytometry on human samples . Clin Cancer Res (2014) ncbi
Abcam
brown rat monoclonal (502-57)
  • immunohistochemistry - paraffin section; mouse; 1:100; fig 3
Abcam NECTIN2 antibody (Abcam, ab16912) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 3). J Histochem Cytochem (2015) ncbi
brown rat monoclonal (502-57)
  • immunocytochemistry; mouse; 1:50; fig 1
  • western blot; mouse
Abcam NECTIN2 antibody (Abcam, Ab16912) was used in immunocytochemistry on mouse samples at 1:50 (fig 1) and in western blot on mouse samples . Biochim Biophys Acta (2014) ncbi
Invitrogen
domestic rabbit polyclonal
  • flow cytometry; human; fig 3
  • immunocytochemistry; human; fig 3
  • western blot; human; fig 1
In order to characterize the influence on NK cell cytotoxicity by differential expression of ligands for DNAM-1 and NKG2D receptors by epithelial ovarian cancer-derived exosomes, Invitrogen NECTIN2 antibody (Pierce, PA5-29757) was used in flow cytometry on human samples (fig 3), in immunocytochemistry on human samples (fig 3) and in western blot on human samples (fig 1). Tumour Biol (2016) ncbi
Abnova
brown rat monoclonal (502-57)
  • flow cytometry; mouse; fig 4
In order to study how DNAM-1 controls NK cell-mediated cytotoxicity and cytokine production, Abnova NECTIN2 antibody (Abnova, MAB3387) was used in flow cytometry on mouse samples (fig 4). J Exp Med (2015) ncbi
BD Biosciences
mouse monoclonal (R2.525)
  • flow cytometry; human; fig 3h
BD Biosciences NECTIN2 antibody (BD Biosciences, 551057) was used in flow cytometry on human samples (fig 3h). Cell (2018) ncbi
mouse monoclonal (R2.525)
  • flow cytometry; human; fig st1
In order to find cell-surface markers specific to human neutrophils, BD Biosciences NECTIN2 antibody (BD, 551057) was used in flow cytometry on human samples (fig st1). Exp Cell Res (2016) ncbi
mouse monoclonal (R2.525)
  • flow cytometry; human; fig s2
BD Biosciences NECTIN2 antibody (BD Biosciences, R2.525) was used in flow cytometry on human samples (fig s2). BMC Cancer (2015) ncbi
mouse monoclonal (R2.525)
  • flow cytometry; human; tbl 1
BD Biosciences NECTIN2 antibody (BD Pharmingen, 551057) was used in flow cytometry on human samples (tbl 1). Cell Transplant (2014) ncbi
Articles Reviewed
  1. Tremblay McLean A, Coenraads S, Kiani Z, Dupuy F, Bernard N. Expression of ligands for activating natural killer cell receptors on cell lines commonly used to assess natural killer cell function. BMC Immunol. 2019;20:8 pubmed publisher
  2. Walwyn Brown K, Guldevall K, Saeed M, Pende D, Önfelt B, MacDonald A, et al. Human NK Cells Lyse Th2-Polarizing Dendritic Cells via NKp30 and DNAM-1. J Immunol. 2018;201:2028-2041 pubmed publisher
  3. Stamm H, Klingler F, Grossjohann E, Muschhammer J, Vettorazzi E, Heuser M, et al. Immune checkpoints PVR and PVRL2 are prognostic markers in AML and their blockade represents a new therapeutic option. Oncogene. 2018;37:5269-5280 pubmed publisher
  4. Barrow A, Edeling M, Trifonov V, Luo J, Goyal P, Bohl B, et al. Natural Killer Cells Control Tumor Growth by Sensing a Growth Factor. Cell. 2018;172:534-548.e19 pubmed publisher
  5. Tauriainen J, Scharf L, Frederiksen J, Naji A, Ljunggren H, Sonnerborg A, et al. Perturbed CD8+ T cell TIGIT/CD226/PVR axis despite early initiation of antiretroviral treatment in HIV infected individuals. Sci Rep. 2017;7:40354 pubmed publisher
  6. Acebes Huerta A, Lorenzo Herrero S, Folgueras A, Huergo Zapico L, Lopez Larrea C, Lopez Soto A, et al. Drug-induced hyperploidy stimulates an antitumor NK cell response mediated by NKG2D and DNAM-1 receptors. Oncoimmunology. 2016;5:e1074378 pubmed
  7. Lakschevitz F, Hassanpour S, Rubin A, Fine N, Sun C, Glogauer M. Identification of neutrophil surface marker changes in health and inflammation using high-throughput screening flow cytometry. Exp Cell Res. 2016;342:200-9 pubmed publisher
  8. Wang P, Swain H, Kunkler A, Chen C, Hutzen B, Arnold M, et al. Neuroblastomas vary widely in their sensitivities to herpes simplex virotherapy unrelated to virus receptors and susceptibility. Gene Ther. 2016;23:135-43 pubmed publisher
  9. Labani Motlagh A, Israelsson P, Ottander U, Lundin E, Nagaev I, Nagaeva O, et al. Differential expression of ligands for NKG2D and DNAM-1 receptors by epithelial ovarian cancer-derived exosomes and its influence on NK cell cytotoxicity. Tumour Biol. 2016;37:5455-66 pubmed publisher
  10. Zhang Z, Wu N, Lu Y, Davidson D, Colonna M, Veillette A. DNAM-1 controls NK cell activation via an ITT-like motif. J Exp Med. 2015;212:2165-82 pubmed publisher
  11. Fernandez L, Valentin J, Zalacain M, Leung W, Patino Garcia A, Perez Martinez A. Activated and expanded natural killer cells target osteosarcoma tumor initiating cells in an NKG2D-NKG2DL dependent manner. Cancer Lett. 2015;368:54-63 pubmed publisher
  12. Yawata N, Selva K, Liu Y, Tan K, Lee A, Siak J, et al. Dynamic change in natural killer cell type in the human ocular mucosa in situ as means of immune evasion by adenovirus infection. Mucosal Immunol. 2016;9:159-70 pubmed publisher
  13. Fionda C, Abruzzese M, Zingoni A, Soriani A, Ricci B, Molfetta R, et al. Nitric oxide donors increase PVR/CD155 DNAM-1 ligand expression in multiple myeloma cells: role of DNA damage response activation. BMC Cancer. 2015;15:17 pubmed publisher
  14. Wu M, Zhang T, Alcon A, Sentman C. DNAM-1-based chimeric antigen receptors enhance T cell effector function and exhibit in vivo efficacy against melanoma. Cancer Immunol Immunother. 2015;64:409-18 pubmed publisher
  15. Nakata H, Wakayama T, Takai Y, Iseki S. Quantitative analysis of the cellular composition in seminiferous tubules in normal and genetically modified infertile mice. J Histochem Cytochem. 2015;63:99-113 pubmed publisher
  16. Bolyard C, Yoo J, Wang P, Saini U, Rath K, Cripe T, et al. Doxorubicin synergizes with 34.5ENVE to enhance antitumor efficacy against metastatic ovarian cancer. Clin Cancer Res. 2014;20:6479-94 pubmed publisher
  17. Zhang X, Lui W. Dysregulation of nectin-2 in the testicular cells: an explanation of cadmium-induced male infertility. Biochim Biophys Acta. 2014;1839:873-84 pubmed publisher
  18. Jacobs S, Plessers J, Pinxteren J, Roobrouck V, Verfaillie C, Van Gool S. Mutual interaction between human multipotent adult progenitor cells and NK cells. Cell Transplant. 2014;23:1099-110 pubmed publisher