This is a Validated Antibody Database (VAD) review about human NCOA4, based on 8 published articles (read how Labome selects the articles), using NCOA4 antibody in all methods. It is aimed to help Labome visitors find the most suited NCOA4 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
NCOA4 synonym: ARA70; ELE1; PTC3; RFG

Knockout validation
Santa Cruz Biotechnology
mouse monoclonal (C-4)
  • western blot knockout validation; mouse; 1:100; loading ...; fig s1b
Santa Cruz Biotechnology NCOA4 antibody (Santa Cruz, sc-373739) was used in western blot knockout validation on mouse samples at 1:100 (fig s1b). Haematologica (2019) ncbi
Santa Cruz Biotechnology
mouse monoclonal (C-4)
  • western blot knockout validation; human; 1:1000; loading ...; fig 3j
Santa Cruz Biotechnology NCOA4 antibody (SantaCruz, sc-373739) was used in western blot knockout validation on human samples at 1:1000 (fig 3j). Cell Rep (2017) ncbi
Santa Cruz Biotechnology
mouse monoclonal (C-4)
  • western blot knockout validation; mouse; loading ...; fig 5a
  • ChIP-Seq; human; loading ...; fig 4c
  • western blot; human; loading ...; fig s3b
Santa Cruz Biotechnology NCOA4 antibody (SantaCruz, sc-373739) was used in western blot knockout validation on mouse samples (fig 5a), in ChIP-Seq on human samples (fig 4c) and in western blot on human samples (fig s3b). Proc Natl Acad Sci U S A (2017) ncbi
Santa Cruz Biotechnology
mouse monoclonal (C-4)
  • western blot knockout validation; mouse; 1:100; loading ...; fig s1b
Santa Cruz Biotechnology NCOA4 antibody (Santa Cruz, sc-373739) was used in western blot knockout validation on mouse samples at 1:100 (fig s1b). Haematologica (2019) ncbi
mouse monoclonal (C-4)
  • western blot knockout validation; human; 1:1000; loading ...; fig 3j
Santa Cruz Biotechnology NCOA4 antibody (SantaCruz, sc-373739) was used in western blot knockout validation on human samples at 1:1000 (fig 3j). Cell Rep (2017) ncbi
mouse monoclonal (C-4)
  • western blot knockout validation; mouse; loading ...; fig 5a
  • ChIP-Seq; human; loading ...; fig 4c
  • western blot; human; loading ...; fig s3b
Santa Cruz Biotechnology NCOA4 antibody (SantaCruz, sc-373739) was used in western blot knockout validation on mouse samples (fig 5a), in ChIP-Seq on human samples (fig 4c) and in western blot on human samples (fig s3b). Proc Natl Acad Sci U S A (2017) ncbi
mouse monoclonal (C-4)
  • western blot; human; 1:200
  • immunohistochemistry - paraffin section; mouse; 1:100
Santa Cruz Biotechnology NCOA4 antibody (Santa Cruz, 373739) was used in western blot on human samples at 1:200 and in immunohistochemistry - paraffin section on mouse samples at 1:100. Nat Cell Biol (2014) ncbi
Abcam
domestic rabbit polyclonal
  • western blot; human; loading ...
Abcam NCOA4 antibody (Abcam, ab86707) was used in western blot on human samples . Theranostics (2021) ncbi
MilliporeSigma
mouse monoclonal (1F11)
  • western blot; human; loading ...; fig 2f
MilliporeSigma NCOA4 antibody (Sigma, SAB1404569) was used in western blot on human samples (fig 2f). Sci Adv (2019) ncbi
mouse monoclonal (1F11)
  • western blot; human
MilliporeSigma NCOA4 antibody (Sigma, SAB1404569) was used in western blot on human samples . J Biol Chem (2014) ncbi
mouse monoclonal (1F11)
  • western blot; human; 1:1000
MilliporeSigma NCOA4 antibody (Sigma, SAB1404569) was used in western blot on human samples at 1:1000. Nature (2014) ncbi
Articles Reviewed
  1. Zhang X, Yu K, Ma L, Qian Z, Tian X, Miao Y, et al. Endogenous glutamate determines ferroptosis sensitivity via ADCY10-dependent YAP suppression in lung adenocarcinoma. Theranostics. 2021;11:5650-5674 pubmed publisher
  2. Yang M, Chen P, Liu J, Zhu S, Kroemer G, Klionsky D, et al. Clockophagy is a novel selective autophagy process favoring ferroptosis. Sci Adv. 2019;5:eaaw2238 pubmed publisher
  3. Santana Codina N, Gableske S, Quiles Del Rey M, Małachowska B, Jedrychowski M, Biancur D, et al. NCOA4 maintains murine erythropoiesis via cell autonomous and non-autonomous mechanisms. Haematologica. 2019;: pubmed publisher
  4. Goodwin J, Dowdle W, Dejesus R, Wang Z, Bergman P, Kobylarz M, et al. Autophagy-Independent Lysosomal Targeting Regulated by ULK1/2-FIP200 and ATG9. Cell Rep. 2017;20:2341-2356 pubmed publisher
  5. Gao X, Lee H, Li W, Platt R, Barrasa M, Ma Q, et al. Thyroid hormone receptor beta and NCOA4 regulate terminal erythrocyte differentiation. Proc Natl Acad Sci U S A. 2017;114:10107-10112 pubmed publisher
  6. Dowdle W, Nyfeler B, Nagel J, Elling R, Liu S, Triantafellow E, et al. Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo. Nat Cell Biol. 2014;16:1069-79 pubmed publisher
  7. Yang N, Tan S, Ng S, Shi Y, Zhou J, Tan K, et al. Artesunate induces cell death in human cancer cells via enhancing lysosomal function and lysosomal degradation of ferritin. J Biol Chem. 2014;289:33425-41 pubmed publisher
  8. Mancias J, Wang X, Gygi S, Harper J, Kimmelman A. Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy. Nature. 2014;509:105-9 pubmed publisher