This is a Validated Antibody Database (VAD) review about human NBR1, based on 20 published articles (read how Labome selects the articles), using NBR1 antibody in all methods. It is aimed to help Labome visitors find the most suited NBR1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
NBR1 synonym: 1A1-3B; IAI3B; M17S2; MIG19

Santa Cruz Biotechnology
mouse monoclonal (4BR)
  • immunohistochemistry - paraffin section; rat; 1:50; fig s2e
  • western blot; rat; 1:400; loading ...; fig s2b
  • immunohistochemistry - paraffin section; human; 1:50; fig s2e
Santa Cruz Biotechnology NBR1 antibody (Santa Cruz, sc-130380) was used in immunohistochemistry - paraffin section on rat samples at 1:50 (fig s2e), in western blot on rat samples at 1:400 (fig s2b) and in immunohistochemistry - paraffin section on human samples at 1:50 (fig s2e). Theranostics (2021) ncbi
mouse monoclonal (4BR)
  • western blot; human; 1:500; loading ...; fig 2g
Santa Cruz Biotechnology NBR1 antibody (Santa Cruz, 4BR) was used in western blot on human samples at 1:500 (fig 2g). Nature (2020) ncbi
mouse monoclonal (4BR)
  • western blot; human; loading ...; fig s1d
Santa Cruz Biotechnology NBR1 antibody (Santa Cruz, sc-130380) was used in western blot on human samples (fig s1d). Dev Cell (2019) ncbi
mouse monoclonal (4BR)
  • western blot; human; loading ...; fig s6b
Santa Cruz Biotechnology NBR1 antibody (Santa, sc-130380) was used in western blot on human samples (fig s6b). Autophagy (2019) ncbi
mouse monoclonal (4BR)
  • immunocytochemistry; human; 1:100; loading ...; fig s3b
In order to recognize the inner mitochondrial membrane protein, prohibitin 2, as a crucial mitophagy receptor involved in targeting mitochondria for autophagic degradation, Santa Cruz Biotechnology NBR1 antibody (Santa Cruz, sc-130380) was used in immunocytochemistry on human samples at 1:100 (fig s3b). Cell (2017) ncbi
mouse monoclonal (4BR)
  • western blot; human; fig 2
  • western blot; mouse; fig 4
Santa Cruz Biotechnology NBR1 antibody (Santa Cruz, sc-130380) was used in western blot on human samples (fig 2) and in western blot on mouse samples (fig 4). Cell Death Dis (2015) ncbi
mouse monoclonal (4BR)
  • western blot; human
Santa Cruz Biotechnology NBR1 antibody (Santa Cruz Biotechnology, sc-130380) was used in western blot on human samples . Cell Death Differ (2014) ncbi
Abnova
mouse monoclonal (6B11)
  • western blot; human; 1:1000; loading ...; fig 4e
Abnova NBR1 antibody (Abnova, H00004077-M01) was used in western blot on human samples at 1:1000 (fig 4e). Autophagy (2017) ncbi
mouse polyclonal
  • western blot; human; 1:500; fig s3
Abnova NBR1 antibody (Abnova, H00004077-A01) was used in western blot on human samples at 1:500 (fig s3). J Cell Biol (2016) ncbi
mouse monoclonal (6B11)
  • western blot; human; fig 2
In order to determine stress resistance to breast cancer cells and neuroblastoma by BAG3 function and estrogen receptor alpha that regulates non-canonical autophagy, Abnova NBR1 antibody (Abnova, 00004077-M01) was used in western blot on human samples (fig 2). Cell Death Dis (2015) ncbi
mouse monoclonal (6B11)
  • western blot; human; 1:5000; fig 3
Abnova NBR1 antibody (Abnova, H00004077-M01) was used in western blot on human samples at 1:5000 (fig 3). Nat Cell Biol (2014) ncbi
Abcam
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 4a
Abcam NBR1 antibody (Abcam, ab126175) was used in western blot on human samples (fig 4a). Autophagy (2020) ncbi
mouse monoclonal
  • western blot; mouse; 1:1000; loading ...; fig s1b
Abcam NBR1 antibody (Abcam, ab55474) was used in western blot on mouse samples at 1:1000 (fig s1b). Nat Commun (2020) ncbi
Novus Biologicals
domestic rabbit polyclonal
  • immunocytochemistry; human; 1:200; fig s3
Novus Biologicals NBR1 antibody (Novus, 71703) was used in immunocytochemistry on human samples at 1:200 (fig s3). J Cell Biol (2016) ncbi
domestic rabbit polyclonal
In order to uncover a role for ATG12-ATG3 in late endosome function that is distinct from autophagy, Novus Biologicals NBR1 antibody (Novus, 71703) was used . Nat Cell Biol (2015) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D2E6)
  • western blot; mouse; 1:2000; loading ...; fig s1e
Cell Signaling Technology NBR1 antibody (CST, 9891) was used in western blot on mouse samples at 1:2000 (fig s1e). PLoS Genet (2021) ncbi
domestic rabbit monoclonal (D2E6)
  • western blot; human; loading ...; fig 2f
Cell Signaling Technology NBR1 antibody (Cell Signaling, 9891) was used in western blot on human samples (fig 2f). Sci Adv (2019) ncbi
domestic rabbit monoclonal (D2E6)
  • western blot; human; loading ...; fig 3c
Cell Signaling Technology NBR1 antibody (Cell Signaling, 9891s) was used in western blot on human samples (fig 3c). Oncogene (2017) ncbi
domestic rabbit monoclonal (D2E6)
  • western blot; human; loading ...; fig 5a
In order to Investigate the regulation of GABARAP ubiquitination and GABARAP-mediated autophagy, Cell Signaling Technology NBR1 antibody (Cell signaling, 9891) was used in western blot on human samples (fig 5a). Curr Biol (2017) ncbi
domestic rabbit monoclonal (D2E6)
  • western blot; human; loading ...; fig 4f
Cell Signaling Technology NBR1 antibody (Cell Signaling, 9891) was used in western blot on human samples (fig 4f). Free Radic Biol Med (2017) ncbi
domestic rabbit monoclonal (D2E6)
  • western blot; mouse; loading ...; fig 2c
Cell Signaling Technology NBR1 antibody (Cell Signaling, 9891) was used in western blot on mouse samples (fig 2c). Autophagy (2017) ncbi
Articles Reviewed
  1. Yamamuro T, Nakamura S, Yamano Y, Endo T, Yanagawa K, Tokumura A, et al. Rubicon prevents autophagic degradation of GATA4 to promote Sertoli cell function. PLoS Genet. 2021;17:e1009688 pubmed publisher
  2. Zheng Q, Shen H, Tong Z, Cheng L, Xu Y, Feng Z, et al. A thermosensitive, reactive oxygen species-responsive, MR409-encapsulated hydrogel ameliorates disc degeneration in rats by inhibiting the secretory autophagy pathway. Theranostics. 2021;11:147-163 pubmed publisher
  3. Yamamoto K, Venida A, Yano J, Biancur D, Kakiuchi M, Gupta S, et al. Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I. Nature. 2020;581:100-105 pubmed publisher
  4. Jo D, Park S, Kim A, Park N, Kim J, Bae J, et al. Loss of HSPA9 induces peroxisomal degradation by increasing pexophagy. Autophagy. 2020;:1-15 pubmed publisher
  5. Cassidy L, Young A, Young C, Soilleux E, Fielder E, Weigand B, et al. Temporal inhibition of autophagy reveals segmental reversal of ageing with increased cancer risk. Nat Commun. 2020;11:307 pubmed publisher
  6. Yang M, Chen P, Liu J, Zhu S, Kroemer G, Klionsky D, et al. Clockophagy is a novel selective autophagy process favoring ferroptosis. Sci Adv. 2019;5:eaaw2238 pubmed publisher
  7. Princely Abudu Y, Pankiv S, Mathai B, Håkon Lystad A, Bindesbøll C, Brenne H, et al. NIPSNAP1 and NIPSNAP2 Act as "Eat Me" Signals for Mitophagy. Dev Cell. 2019;49:509-525.e12 pubmed publisher
  8. Birgisdottir A, Mouilleron S, Bhujabal Z, Wirth M, Sjøttem E, Evjen G, et al. Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs. Autophagy. 2019;15:1333-1355 pubmed publisher
  9. Jiang X, Bao Y, Liu H, Kou X, Zhang Z, Sun F, et al. VPS34 stimulation of p62 phosphorylation for cancer progression. Oncogene. 2017;36:6850-6862 pubmed publisher
  10. Joachim J, Razi M, Judith D, Wirth M, Calamita E, Encheva V, et al. Centriolar Satellites Control GABARAP Ubiquitination and GABARAP-Mediated Autophagy. Curr Biol. 2017;27:2123-2136.e7 pubmed publisher
  11. Potes Y, de Luxán Delgado B, Rodríguez González S, Guimarães M, Solano J, Fernández Fernández M, et al. Overweight in elderly people induces impaired autophagy in skeletal muscle. Free Radic Biol Med. 2017;110:31-41 pubmed publisher
  12. Law K, Bronte Tinkew D, Di Pietro E, Snowden A, Jones R, Moser A, et al. The peroxisomal AAA ATPase complex prevents pexophagy and development of peroxisome biogenesis disorders. Autophagy. 2017;13:868-884 pubmed publisher
  13. Liu J, Wang H, Gu J, Deng T, Yuan Z, Hu B, et al. BECN1-dependent CASP2 incomplete autophagy induction by binding to rabies virus phosphoprotein. Autophagy. 2017;13:739-753 pubmed publisher
  14. Wei Y, Chiang W, Sumpter R, Mishra P, Levine B. Prohibitin 2 Is an Inner Mitochondrial Membrane Mitophagy Receptor. Cell. 2017;168:224-238.e10 pubmed publisher
  15. Kenific C, Stehbens S, Goldsmith J, Leidal A, Faure N, Ye J, et al. NBR1 enables autophagy-dependent focal adhesion turnover. J Cell Biol. 2016;212:577-90 pubmed publisher
  16. Shi J, Fung G, Deng H, Zhang J, Fiesel F, Springer W, et al. NBR1 is dispensable for PARK2-mediated mitophagy regardless of the presence or absence of SQSTM1. Cell Death Dis. 2015;6:e1943 pubmed publisher
  17. Felzen V, Hiebel C, Koziollek Drechsler I, Reißig S, Wolfrum U, Kögel D, et al. Estrogen receptor α regulates non-canonical autophagy that provides stress resistance to neuroblastoma and breast cancer cells and involves BAG3 function. Cell Death Dis. 2015;6:e1812 pubmed publisher
  18. Murrow L, Malhotra R, Debnath J. ATG12-ATG3 interacts with Alix to promote basal autophagic flux and late endosome function. Nat Cell Biol. 2015;17:300-10 pubmed publisher
  19. Dowdle W, Nyfeler B, Nagel J, Elling R, Liu S, Triantafellow E, et al. Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo. Nat Cell Biol. 2014;16:1069-79 pubmed publisher
  20. Shi J, Fung G, Piesik P, Zhang J, Luo H. Dominant-negative function of the C-terminal fragments of NBR1 and SQSTM1 generated during enteroviral infection. Cell Death Differ. 2014;21:1432-41 pubmed publisher