This is a Validated Antibody Database (VAD) review about human Mre11, based on 41 published articles (read how Labome selects the articles), using Mre11 antibody in all methods. It is aimed to help Labome visitors find the most suited Mre11 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Mre11 synonym: ATLD; HNGS1; MRE11A; MRE11B

GeneTex
mouse monoclonal (12D7)
  • immunocytochemistry; human; 1:500; loading ...; fig 4e
GeneTex Mre11 antibody (GeneTex, GTX70212) was used in immunocytochemistry on human samples at 1:500 (fig 4e). Nucleic Acids Res (2021) ncbi
mouse monoclonal (12D7)
  • western blot; human; loading ...; fig 4c
GeneTex Mre11 antibody (GeneTex, GTX70212) was used in western blot on human samples (fig 4c). Cell Host Microbe (2017) ncbi
mouse monoclonal (12D7)
  • western blot; human; loading ...; fig s2b
In order to test whether the attenuation of non-homologous end joining repair is sufficient to compromise homologous recombination in DEK knockout mice, GeneTex Mre11 antibody (GeneTex, GTX70212) was used in western blot on human samples (fig s2b). Sci Rep (2017) ncbi
mouse monoclonal (12D7)
  • immunocytochemistry; human; fig 2
In order to study how the Fanconi anemia pathway promotes homologous recombination at stalled replication forks, GeneTex Mre11 antibody (GeneTex, GTX70212) was used in immunocytochemistry on human samples (fig 2). Nucleic Acids Res (2016) ncbi
mouse monoclonal (12D7)
  • immunocytochemistry; human; fig 6
GeneTex Mre11 antibody (Genetex, GTX70212) was used in immunocytochemistry on human samples (fig 6). Viruses (2015) ncbi
mouse monoclonal (12D7)
  • western blot; human; fig 5
GeneTex Mre11 antibody (GeneTex, GTX70212) was used in western blot on human samples (fig 5). BMC Biol (2015) ncbi
mouse monoclonal (12D7)
  • western blot; human; fig 4
GeneTex Mre11 antibody (GeneTex, GTX70212) was used in western blot on human samples (fig 4). PLoS ONE (2015) ncbi
mouse monoclonal (12D7)
  • immunocytochemistry; human; 1:200; fig s6c
In order to assess the functionality of BRCA1 in the heterozygous state, GeneTex Mre11 antibody (Genetex, GTX70212) was used in immunocytochemistry on human samples at 1:200 (fig s6c). Nat Commun (2014) ncbi
mouse monoclonal (12D7)
  • western blot; human; fig 3
GeneTex Mre11 antibody (GeneTex, GTX70212) was used in western blot on human samples (fig 3). Oncogene (2015) ncbi
mouse monoclonal (12D7)
  • immunocytochemistry; mouse; 1:100; fig s3
GeneTex Mre11 antibody (GeneTex, GTX70212) was used in immunocytochemistry on mouse samples at 1:100 (fig s3). FASEB J (2014) ncbi
mouse monoclonal (12D7)
  • immunocytochemistry; human; fig 2d
  • western blot; human; fig 6a
GeneTex Mre11 antibody (GeneTex, GTX70212) was used in immunocytochemistry on human samples (fig 2d) and in western blot on human samples (fig 6a). Mol Cell (2014) ncbi
mouse monoclonal (12D7)
  • immunocytochemistry; human; 1:1000; fig 5
GeneTex Mre11 antibody (GeneTex, GTX70212) was used in immunocytochemistry on human samples at 1:1000 (fig 5). J Virol (2011) ncbi
mouse monoclonal (12D7)
  • western blot; human
GeneTex Mre11 antibody (GeneTex, #GTX70212) was used in western blot on human samples . Cancer Res (2011) ncbi
mouse monoclonal (12D7)
  • western blot; human
GeneTex Mre11 antibody (Genetex, GTX70212) was used in western blot on human samples . Cell Cycle (2010) ncbi
Abcam
mouse monoclonal (12D7)
  • western blot; human; 1:1000; loading ...; fig 1s1d
Abcam Mre11 antibody (abcam, ab214) was used in western blot on human samples at 1:1000 (fig 1s1d). elife (2020) ncbi
mouse monoclonal (12D7)
  • western blot; human; loading ...; fig s9a
  • western blot; mouse; loading ...; fig 4a
Abcam Mre11 antibody (Abcam, ab214) was used in western blot on human samples (fig s9a) and in western blot on mouse samples (fig 4a). Nat Struct Mol Biol (2018) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 4
Abcam Mre11 antibody (Abcam, ab33125) was used in western blot on human samples (fig 4). Nucleic Acids Res (2016) ncbi
domestic rabbit polyclonal
  • immunoprecipitation; human; fig 3
  • immunocytochemistry; human; fig 3
  • western blot; human; fig 1
Abcam Mre11 antibody (Abcam, ab33125) was used in immunoprecipitation on human samples (fig 3), in immunocytochemistry on human samples (fig 3) and in western blot on human samples (fig 1). BMC Cancer (2016) ncbi
mouse monoclonal (12D7)
  • immunoprecipitation; human; fig 5a
Abcam Mre11 antibody (Abcam, ab214) was used in immunoprecipitation on human samples (fig 5a). Nat Commun (2015) ncbi
mouse monoclonal (12D7)
  • western blot; human; fig s1c
  • western blot; mouse; fig 5a
Abcam Mre11 antibody (Abcam, ab214) was used in western blot on human samples (fig s1c) and in western blot on mouse samples (fig 5a). Cell Death Differ (2016) ncbi
mouse monoclonal (12D7)
  • western blot; human; 1:500; fig s2
Abcam Mre11 antibody (Abcam, ab214) was used in western blot on human samples at 1:500 (fig s2). Nat Cell Biol (2014) ncbi
mouse monoclonal (12D7)
  • immunocytochemistry; mouse
Abcam Mre11 antibody (Abcam, ab214) was used in immunocytochemistry on mouse samples . PLoS ONE (2014) ncbi
mouse monoclonal (12D7)
  • immunocytochemistry; human; 1:200 and 1:750
  • western blot; human
Abcam Mre11 antibody (Abcam, ab214) was used in immunocytochemistry on human samples at 1:200 and 1:750 and in western blot on human samples . PLoS ONE (2014) ncbi
mouse monoclonal (12D7)
  • western blot; human
Abcam Mre11 antibody (Abcam, AB214) was used in western blot on human samples . Oncotarget (2014) ncbi
mouse monoclonal (12D7)
  • immunocytochemistry; human; 1:1000
  • western blot; human; 1:500-1:1000
Abcam Mre11 antibody (Abcam, ab214) was used in immunocytochemistry on human samples at 1:1000 and in western blot on human samples at 1:500-1:1000. PLoS ONE (2013) ncbi
mouse monoclonal (12D7)
  • immunohistochemistry - paraffin section; human; 1:200
Abcam Mre11 antibody (Abcam, ab214) was used in immunohistochemistry - paraffin section on human samples at 1:200. World J Gastroenterol (2013) ncbi
Novus Biologicals
domestic rabbit polyclonal (OTI2B3)
  • western blot; human; 1:5000; loading ...; fig s1a
  • ChIP-Seq; mouse; loading ...; fig s3a
  • western blot; mouse; 1:5000; loading ...; fig s1a, s1b
Novus Biologicals Mre11 antibody (Novus, NB100-142) was used in western blot on human samples at 1:5000 (fig s1a), in ChIP-Seq on mouse samples (fig s3a) and in western blot on mouse samples at 1:5000 (fig s1a, s1b). Science (2019) ncbi
domestic rabbit polyclonal (OTI2B3)
  • western blot; human; 1:1000; loading ...; fig s2f
Novus Biologicals Mre11 antibody (Novus Biological, NB100-C142) was used in western blot on human samples at 1:1000 (fig s2f). Nucleic Acids Res (2019) ncbi
domestic rabbit polyclonal (OTI2B3)
  • immunocytochemistry; human; loading ...; fig s5l
  • western blot; human; loading ...; fig s5a
Novus Biologicals Mre11 antibody (Novus, NB 100-142) was used in immunocytochemistry on human samples (fig s5l) and in western blot on human samples (fig s5a). Cell (2019) ncbi
Santa Cruz Biotechnology
mouse monoclonal (18)
  • western blot; human; 1:100; loading ...; fig s12e
  • immunocytochemistry; mouse; 1:500; loading ...; fig s9a
  • western blot; mouse; 1:100; loading ...; fig s13a
Santa Cruz Biotechnology Mre11 antibody (Santa Cruz, SC-135992) was used in western blot on human samples at 1:100 (fig s12e), in immunocytochemistry on mouse samples at 1:500 (fig s9a) and in western blot on mouse samples at 1:100 (fig s13a). Science (2016) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot; human; loading ...
Cell Signaling Technology Mre11 antibody (Cell Signalling Technologies, 4895S) was used in western blot on human samples . elife (2020) ncbi
domestic rabbit monoclonal (31H4)
  • western blot; human; loading ...; fig 6b
Cell Signaling Technology Mre11 antibody (Cell Signaling, 4847) was used in western blot on human samples (fig 6b). J Cancer Res Clin Oncol (2020) ncbi
domestic rabbit monoclonal (31H4)
  • reverse phase protein lysate microarray; human; loading ...; fig st6
In order to characterize the molecular identity of uterine carcinosarcomas., Cell Signaling Technology Mre11 antibody (CST, 4847) was used in reverse phase protein lysate microarray on human samples (fig st6). Cancer Cell (2017) ncbi
domestic rabbit monoclonal (31H4)
  • western blot; human; fig 4b
Cell Signaling Technology Mre11 antibody (Cell Signaling Technology, 4847) was used in western blot on human samples (fig 4b). Sci Rep (2017) ncbi
domestic rabbit monoclonal (31H4)
  • reverse phase protein lysate microarray; human; loading ...; fig 3a
In order to describe the features of 228 primary cervical cancers, Cell Signaling Technology Mre11 antibody (Cell Signaling, 4847) was used in reverse phase protein lysate microarray on human samples (fig 3a). Nature (2017) ncbi
domestic rabbit monoclonal (31H4)
  • immunocytochemistry; human; loading ...; fig 3e
In order to clarify the role of T cell aging in rheumatoid arthritis, Cell Signaling Technology Mre11 antibody (Cell signaling, 4847P) was used in immunocytochemistry on human samples (fig 3e). Immunity (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; fig 2
Cell Signaling Technology Mre11 antibody (Cell Signaling, 4895S) was used in western blot on human samples at 1:1000 (fig 2). Sci Rep (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 1
Cell Signaling Technology Mre11 antibody (Cell Signaling, 4895) was used in western blot on human samples (fig 1). Mol Cancer Res (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; fig 6
Cell Signaling Technology Mre11 antibody (Cell Signaling Technology, 4895) was used in western blot on mouse samples (fig 6). Oncogene (2016) ncbi
BD Biosciences
mouse monoclonal (18/MRE11)
  • other; human; loading ...; fig st1
In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, BD Biosciences Mre11 antibody (BD, 18) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi
mouse monoclonal (18/MRE11)
  • western blot; human; 1:1000; fig 3
BD Biosciences Mre11 antibody (BD Biosciences, 611366) was used in western blot on human samples at 1:1000 (fig 3). Nucleic Acids Res (2016) ncbi
Articles Reviewed
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  2. Lochab S, Singh Y, Sengupta S, Nandicoori V. Mycobacterium tuberculosis exploits host ATM kinase for survival advantage through SecA2 secretome. elife. 2020;9: pubmed publisher
  3. Onn L, Portillo M, Ilic S, Cleitman G, Stein D, Kaluski S, et al. SIRT6 is a DNA double-strand break sensor. elife. 2020;9: pubmed publisher
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  6. Alfano L, Caporaso A, Altieri A, Dell Aquila M, Landi C, Bini L, et al. Depletion of the RNA binding protein HNRNPD impairs homologous recombination by inhibiting DNA-end resection and inducing R-loop accumulation. Nucleic Acids Res. 2019;47:4068-4085 pubmed publisher
  7. Jachimowicz R, Beleggia F, Isensee J, Velpula B, Goergens J, Bustos M, et al. UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors. Cell. 2019;176:505-519.e22 pubmed publisher
  8. Lei L, Chen H, Xue W, Yang B, Hu B, Wei J, et al. APOBEC3 induces mutations during repair of CRISPR-Cas9-generated DNA breaks. Nat Struct Mol Biol. 2018;25:45-52 pubmed publisher
  9. Meyerson N, Zhou L, Guo Y, Zhao C, Tao Y, Krug R, et al. Nuclear TRIM25 Specifically Targets Influenza Virus Ribonucleoproteins to Block the Onset of RNA Chain Elongation. Cell Host Microbe. 2017;22:627-638.e7 pubmed publisher
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  12. Yamauchi M, Shibata A, Suzuki K, Suzuki M, Niimi A, Kondo H, et al. Regulation of pairing between broken DNA-containing chromatin regions by Ku80, DNA-PKcs, ATM, and 53BP1. Sci Rep. 2017;7:41812 pubmed publisher
  13. . Integrated genomic and molecular characterization of cervical cancer. Nature. 2017;543:378-384 pubmed publisher
  14. Li Y, Shen Y, Hohensinner P, Ju J, Wen Z, Goodman S, et al. Deficient Activity of the Nuclease MRE11A Induces T Cell Aging and Promotes Arthritogenic Effector Functions in Patients with Rheumatoid Arthritis. Immunity. 2016;45:903-916 pubmed publisher
  15. Kanakkanthara A, Jeganathan K, Limzerwala J, Baker D, Hamada M, Nam H, et al. Cyclin A2 is an RNA binding protein that controls Mre11 mRNA translation. Science. 2016;353:1549-1552 pubmed
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  22. Ortega Atienza S, Wong V, Deloughery Z, Luczak M, Zhitkovich A. ATM and KAT5 safeguard replicating chromatin against formaldehyde damage. Nucleic Acids Res. 2016;44:198-209 pubmed publisher
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  27. Harten S, Oey H, Bourke L, Bharti V, Isbel L, Daxinger L, et al. The recently identified modifier of murine metastable epialleles, Rearranged L-Myc Fusion, is involved in maintaining epigenetic marks at CpG island shores and enhancers. BMC Biol. 2015;13:21 pubmed publisher
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  29. Pathania S, Bade S, Le Guillou M, Burke K, Reed R, Bowman Colin C, et al. BRCA1 haploinsufficiency for replication stress suppression in primary cells. Nat Commun. 2014;5:5496 pubmed publisher
  30. Hühn D, Kousholt A, Sørensen C, Sartori A. miR-19, a component of the oncogenic miR-17∼92 cluster, targets the DNA-end resection factor CtIP. Oncogene. 2015;34:3977-84 pubmed publisher
  31. Larsen D, Hari F, Clapperton J, Gwerder M, Gutsche K, Altmeyer M, et al. The NBS1-Treacle complex controls ribosomal RNA transcription in response to DNA damage. Nat Cell Biol. 2014;16:792-803 pubmed publisher
  32. Clynes D, Jelinska C, Xella B, Ayyub H, Taylor S, Mitson M, et al. ATRX dysfunction induces replication defects in primary mouse cells. PLoS ONE. 2014;9:e92915 pubmed publisher
  33. Becker A, Durante M, Taucher Scholz G, Jakob B. ATM alters the otherwise robust chromatin mobility at sites of DNA double-strand breaks (DSBs) in human cells. PLoS ONE. 2014;9:e92640 pubmed publisher
  34. Martin R, Kerr M, Teo M, Jevons S, Koritzinsky M, Wouters B, et al. Post-transcriptional regulation of MRE11 expression in muscle-invasive bladder tumours. Oncotarget. 2014;5:993-1003 pubmed
  35. Schröder Heurich B, Wieland B, Lavin M, Schindler D, Dork T. Protective role of RAD50 on chromatin bridges during abnormal cytokinesis. FASEB J. 2014;28:1331-41 pubmed publisher
  36. Shibata A, Moiani D, Arvai A, Perry J, Harding S, Genois M, et al. DNA double-strand break repair pathway choice is directed by distinct MRE11 nuclease activities. Mol Cell. 2014;53:7-18 pubmed publisher
  37. Birkenkamp Demtroder K, Hahn S, Mansilla F, Thorsen K, Maghnouj A, Christensen R, et al. Keratin23 (KRT23) knockdown decreases proliferation and affects the DNA damage response of colon cancer cells. PLoS ONE. 2013;8:e73593 pubmed publisher
  38. Zhang Z, Liu Y, Yin X, Zhan P, Gu Y, Ni X. Loss of BRCA1 expression leads to worse survival in patients with gastric carcinoma. World J Gastroenterol. 2013;19:1968-74 pubmed publisher
  39. Karen K, Hearing P. Adenovirus core protein VII protects the viral genome from a DNA damage response at early times after infection. J Virol. 2011;85:4135-42 pubmed publisher
  40. Anderson V, Walton M, Eve P, Boxall K, Antoni L, Caldwell J, et al. CCT241533 is a potent and selective inhibitor of CHK2 that potentiates the cytotoxicity of PARP inhibitors. Cancer Res. 2011;71:463-72 pubmed publisher
  41. Guo Z, Deshpande R, Paull T. ATM activation in the presence of oxidative stress. Cell Cycle. 2010;9:4805-11 pubmed