This is a Validated Antibody Database (VAD) review about human MURR1, based on 3 published articles (read how Labome selects the articles), using MURR1 antibody in all methods. It is aimed to help Labome visitors find the most suited MURR1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
MURR1 synonym: C2orf5; MURR1; COMM domain-containing protein 1; copper metabolism (Murr1) domain containing 1; copper metabolism gene MURR1; protein Murr1

Knockout validation
R&D Systems
mouse monoclonal (762203)
  • immunocytochemistry knockout validation; mouse; 1:400; fig 3
In order to analyze how WASH- and CCC-mediated endosomal sorting of LDLr is needed for regular clearance of circulating LDL, R&D Systems MURR1 antibody (R&D Systems, MAB7526) was used in immunocytochemistry knockout validation on mouse samples at 1:400 (fig 3). Nat Commun (2016) ncbi
R&D Systems
mouse monoclonal (762203)
  • western blot knockout validation; human; fig 2
  • immunoprecipitation; human; fig 2
  • immunocytochemistry; human; 10 ug/ml; fig 3
  • immunocytochemistry knockout validation; mouse; 10 ug/ml; fig s7
  • western blot; mouse; fig s6
In order to elucidate the role of COMMD1 in copper homeostasis, R&D Systems MURR1 antibody (R & D systems, MAB7526) was used in western blot knockout validation on human samples (fig 2), in immunoprecipitation on human samples (fig 2), in immunocytochemistry on human samples at 10 ug/ml (fig 3), in immunocytochemistry knockout validation on mouse samples at 10 ug/ml (fig s7) and in western blot on mouse samples (fig s6). Mol Biol Cell (2015) ncbi
Proteintech Group
rabbit polyclonal
  • western blot; human; 1:1000; fig 3
  • western blot knockout validation; dog; 1:1000; fig 1
  • western blot knockout validation; mouse; 1:1000; fig 3
In order to analyze how WASH- and CCC-mediated endosomal sorting of LDLr is needed for regular clearance of circulating LDL, Proteintech Group MURR1 antibody (Proteintech, 11938-1-AP) was used in western blot on human samples at 1:1000 (fig 3), in western blot knockout validation on dog samples at 1:1000 (fig 1) and in western blot knockout validation on mouse samples at 1:1000 (fig 3). Nat Commun (2016) ncbi
R&D Systems
mouse monoclonal (762203)
  • immunocytochemistry knockout validation; mouse; 1:400; fig 3
In order to analyze how WASH- and CCC-mediated endosomal sorting of LDLr is needed for regular clearance of circulating LDL, R&D Systems MURR1 antibody (R&D Systems, MAB7526) was used in immunocytochemistry knockout validation on mouse samples at 1:400 (fig 3). Nat Commun (2016) ncbi
mouse monoclonal (762203)
  • western blot knockout validation; human; fig 2
  • immunoprecipitation; human; fig 2
  • immunocytochemistry; human; 10 ug/ml; fig 3
  • immunocytochemistry knockout validation; mouse; 10 ug/ml; fig s7
  • western blot; mouse; fig s6
In order to elucidate the role of COMMD1 in copper homeostasis, R&D Systems MURR1 antibody (R & D systems, MAB7526) was used in western blot knockout validation on human samples (fig 2), in immunoprecipitation on human samples (fig 2), in immunocytochemistry on human samples at 10 ug/ml (fig 3), in immunocytochemistry knockout validation on mouse samples at 10 ug/ml (fig s7) and in western blot on mouse samples (fig s6). Mol Biol Cell (2015) ncbi
Proteintech Group
rabbit polyclonal
  • western blot; human; 1:1000; fig 3
  • western blot knockout validation; dog; 1:1000; fig 1
  • western blot knockout validation; mouse; 1:1000; fig 3
In order to analyze how WASH- and CCC-mediated endosomal sorting of LDLr is needed for regular clearance of circulating LDL, Proteintech Group MURR1 antibody (Proteintech, 11938-1-AP) was used in western blot on human samples at 1:1000 (fig 3), in western blot knockout validation on dog samples at 1:1000 (fig 1) and in western blot knockout validation on mouse samples at 1:1000 (fig 3). Nat Commun (2016) ncbi
rabbit polyclonal
  • western blot; mouse
Proteintech Group MURR1 antibody (Proteintech Group, 11938-1-AP) was used in western blot on mouse samples . Biochim Biophys Acta (2014) ncbi
Articles Reviewed
  1. Bartuzi P, Billadeau D, Favier R, Rong S, Dekker D, Fedoseienko A, et al. CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL. Nat Commun. 2016;7:10961 pubmed publisher
  2. Phillips Krawczak C, Singla A, Starokadomskyy P, Deng Z, Osborne D, Li H, et al. COMMD1 is linked to the WASH complex and regulates endosomal trafficking of the copper transporter ATP7A. Mol Biol Cell. 2015;26:91-103 pubmed publisher
  3. Bartuzi P, Wijshake T, Dekker D, Fedoseienko A, Kloosterhuis N, Youssef S, et al. A cell-type-specific role for murine Commd1 in liver inflammation. Biochim Biophys Acta. 2014;1842:2257-65 pubmed publisher