This is a Validated Antibody Database (VAD) review about human MTHFD2, based on 4 published articles (read how Labome selects the articles), using MTHFD2 antibody in all methods. It is aimed to help Labome visitors find the most suited MTHFD2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
MTHFD2 synonym: NMDMC

Knockout validation
Invitrogen
domestic rabbit polyclonal
  • western blot knockout validation; human; 1:1000; loading ...; fig 3a
Invitrogen MTHFD2 antibody (Thermo Fisher Scientific, PA5-28169) was used in western blot knockout validation on human samples at 1:1000 (fig 3a). Exp Ther Med (2021) ncbi
Abcam
domestic rabbit polyclonal
  • western blot knockout validation; human; loading ...; fig 1d
Abcam MTHFD2 antibody (Abcam, ab151447) was used in western blot knockout validation on human samples (fig 1d). Nature (2018) ncbi
Invitrogen
domestic rabbit polyclonal
  • western blot knockout validation; human; 1:1000; loading ...; fig 3a
Invitrogen MTHFD2 antibody (Thermo Fisher Scientific, PA5-28169) was used in western blot knockout validation on human samples at 1:1000 (fig 3a). Exp Ther Med (2021) ncbi
domestic rabbit polyclonal
In order to study the effect of Taz-knockdown on the mitochondrial processes in cardiac tissues, Invitrogen MTHFD2 antibody (Pierce, PA5-28169) was used . PLoS ONE (2015) ncbi
Abnova
mouse monoclonal (4G7-2G3)
  • immunohistochemistry - paraffin section; human; fig 4
Abnova MTHFD2 antibody (Abnova, H00010797-M01) was used in immunohistochemistry - paraffin section on human samples (fig 4). Sci Rep (2015) ncbi
Abcam
domestic rabbit polyclonal
  • western blot knockout validation; human; loading ...; fig 1d
Abcam MTHFD2 antibody (Abcam, ab151447) was used in western blot knockout validation on human samples (fig 1d). Nature (2018) ncbi
Articles Reviewed
  1. Huang J, Qin Y, Lin C, Huang X, Zhang F. MTHFD2 facilitates breast cancer cell proliferation via the AKT signaling pathway. Exp Ther Med. 2021;22:703 pubmed publisher
  2. Morscher R, Ducker G, Li S, Mayer J, Gitai Z, Sperl W, et al. Mitochondrial translation requires folate-dependent tRNA methylation. Nature. 2018;554:128-132 pubmed publisher
  3. Gustafsson Sheppard N, Jarl L, Mahadessian D, Strittmatter L, Schmidt A, Madhusudan N, et al. The folate-coupled enzyme MTHFD2 is a nuclear protein and promotes cell proliferation. Sci Rep. 2015;5:15029 pubmed publisher
  4. Huang Y, Powers C, Madala S, Greis K, Haffey W, Towbin J, et al. Cardiac metabolic pathways affected in the mouse model of barth syndrome. PLoS ONE. 2015;10:e0128561 pubmed publisher