This is a Validated Antibody Database (VAD) review about human MTAP, based on 6 published articles (read how Labome selects the articles), using MTAP antibody in all methods. It is aimed to help Labome visitors find the most suited MTAP antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
MTAP synonym: BDMF; DMSFH; DMSMFH; HEL-249; LGMBF; MSAP; c86fus

Knockout validation
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot knockout validation; human; loading ...; fig 7c
  • immunohistochemistry; human; 1:400; loading ...; fig 7a
Cell Signaling Technology MTAP antibody (Cell Signaling, 4158) was used in western blot knockout validation on human samples (fig 7c) and in immunohistochemistry on human samples at 1:400 (fig 7a). Nat Commun (2021) ncbi
Abnova
mouse monoclonal (2G4)
  • western blot; human; loading ...; fig 1c
Abnova MTAP antibody (Abnova, 2G4) was used in western blot on human samples (fig 1c). EMBO Rep (2022) ncbi
mouse monoclonal (2G4)
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; tbl 2
Abnova MTAP antibody (Abnova, H00004507-M01) was used in immunohistochemistry - paraffin section on human samples at 1:100 (tbl 2). Neurol Med Chir (Tokyo) (2020) ncbi
mouse monoclonal (2G4)
  • immunohistochemistry; human; 1:2000
Abnova MTAP antibody (Abnova, 2G4) was used in immunohistochemistry on human samples at 1:2000. Cancer Res (2011) ncbi
Santa Cruz Biotechnology
mouse monoclonal (42-T)
  • western blot; mouse; loading ...; fig 3p
  • western blot; human; loading ...; fig 3g
Santa Cruz Biotechnology MTAP antibody (Santa Cruz, sc-100782) was used in western blot on mouse samples (fig 3p) and in western blot on human samples (fig 3g). Cell (2020) ncbi
mouse monoclonal (42-T)
  • western blot; human; loading ...; fig 2a
Santa Cruz Biotechnology MTAP antibody (Santa Cruz, 42-T) was used in western blot on human samples (fig 2a). Cancer Chemother Pharmacol (2015) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot knockout validation; human; loading ...; fig 7c
  • immunohistochemistry; human; 1:400; loading ...; fig 7a
Cell Signaling Technology MTAP antibody (Cell Signaling, 4158) was used in western blot knockout validation on human samples (fig 7c) and in immunohistochemistry on human samples at 1:400 (fig 7a). Nat Commun (2021) ncbi
Articles Reviewed
  1. Chang W, Chen Y, Hsiao Y, Chiang C, Wang C, Chang Y, et al. Reduced symmetric dimethylation stabilizes vimentin and promotes metastasis in MTAP-deficient lung cancer. EMBO Rep. 2022;23:e54265 pubmed publisher
  2. Bruce J, To K, Lui V, Chung G, Chan Y, Tsang C, et al. Whole-genome profiling of nasopharyngeal carcinoma reveals viral-host co-operation in inflammatory NF-κB activation and immune escape. Nat Commun. 2021;12:4193 pubmed publisher
  3. Cader M, de Almeida Rodrigues R, West J, Sewell G, Md Ibrahim M, Reikine S, et al. FAMIN Is a Multifunctional Purine Enzyme Enabling the Purine Nucleotide Cycle. Cell. 2020;180:278-295.e23 pubmed publisher
  4. Enomoto T, Aoki M, Hamasaki M, Abe H, Nonaka M, Inoue T, et al. Midline Glioma in Adults: Clinicopathological, Genetic, and Epigenetic Analysis. Neurol Med Chir (Tokyo). 2020;60:136-146 pubmed publisher
  5. Tedeschi P, Kathari Y, Johnson Farley N, Bertino J. Methylthioadenosine phosphorylase (MTAP)-deficient T-cell ALL xenografts are sensitive to pralatrexate and 6-thioguanine alone and in combination. Cancer Chemother Pharmacol. 2015;75:1247-52 pubmed publisher
  6. Rose A, Poliseno L, Wang J, Clark M, Pearlman A, Wang G, et al. Integrative genomics identifies molecular alterations that challenge the linear model of melanoma progression. Cancer Res. 2011;71:2561-71 pubmed publisher