This is a Validated Antibody Database (VAD) review about human MSH6, based on 21 published articles (read how Labome selects the articles), using MSH6 antibody in all methods. It is aimed to help Labome visitors find the most suited MSH6 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
MSH6 synonym: GTBP; GTMBP; HNPCC5; HSAP; p160

Knockout validation
Cell Signaling Technology
domestic rabbit monoclonal (D60G2)
  • western blot knockout validation; human; 1:1000; loading ...; fig s1b
Cell Signaling Technology MSH6 antibody (Cell Signaling, D60G2) was used in western blot knockout validation on human samples at 1:1000 (fig s1b). Nat Commun (2018) ncbi
BD Biosciences
mouse monoclonal (44/MSH6)
  • western blot knockout validation; mouse; 1:1000; fig 4
BD Biosciences MSH6 antibody (BD Biosciences, 610918) was used in western blot knockout validation on mouse samples at 1:1000 (fig 4). PLoS Genet (2016) ncbi
Invitrogen
mouse monoclonal (44)
  • immunohistochemistry - paraffin section; human
In order to discuss the diagnosis of colorectal cancer and the need for genetic testing for Lynch Syndrome in young patients, Invitrogen MSH6 antibody (Zymed, 08-1374) was used in immunohistochemistry - paraffin section on human samples . BMC Surg (2014) ncbi
mouse monoclonal (44)
  • immunohistochemistry - paraffin section; human
In order to examine patients with renal medullary carcinoma with and without sickle cell anemia, Invitrogen MSH6 antibody (Zymed, 44) was used in immunohistochemistry - paraffin section on human samples . Hum Pathol (2011) ncbi
mouse monoclonal (44)
  • immunohistochemistry - paraffin section; human
In order to measure the frequency of mismatch repair deficiencies in women diagnosed with endometrial cancer who are at-risk for Lynch syndrome, Invitrogen MSH6 antibody (Zymed, 44) was used in immunohistochemistry - paraffin section on human samples . Fam Cancer (2010) ncbi
mouse monoclonal (44)
  • immunohistochemistry - paraffin section; human
In order to correlate microstellite instability and other clinicopathologic markers with survival of patients with high grade endometrial carcinoma, Invitrogen MSH6 antibody (Zymed, 44) was used in immunohistochemistry - paraffin section on human samples . Gynecol Oncol (2009) ncbi
mouse monoclonal (44)
  • immunohistochemistry - paraffin section; human
In order to detect expression of MMR gene products hMSH2 and hMSH6 in urothelial carcinoma of the bladder, Invitrogen MSH6 antibody (Zymed Laboratories, 44) was used in immunohistochemistry - paraffin section on human samples . APMIS (2008) ncbi
Abcam
domestic rabbit monoclonal (EPR3945)
  • western blot; human; loading ...; fig e8k
Abcam MSH6 antibody (Abcam, ab92471) was used in western blot on human samples (fig e8k). Nature (2019) ncbi
MilliporeSigma
  • immunocytochemistry; human
In order to assess if PC1 and PC2 facilitate cancer aggressiveness, MilliporeSigma MSH6 antibody (Ventana, 790-4455) was used in immunocytochemistry on human samples . Int J Cancer (2015) ncbi
Dako
domestic rabbit monoclonal (EP49)
  • immunohistochemistry - paraffin section; human; loading ...; fig 1
Dako MSH6 antibody (Dako, IR086) was used in immunohistochemistry - paraffin section on human samples (fig 1). Cancer Manag Res (2020) ncbi
domestic rabbit monoclonal (EP49)
  • immunohistochemistry; human; 1:1000; loading ...; fig 1f
Dako MSH6 antibody (Dako, EP49) was used in immunohistochemistry on human samples at 1:1000 (fig 1f). PLoS ONE (2020) ncbi
domestic rabbit monoclonal (EP49)
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; tbl 1
Dako MSH6 antibody (Dako, M3646) was used in immunohistochemistry - paraffin section on human samples at 1:100 (tbl 1). Br J Cancer (2016) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D60G2)
  • western blot knockout validation; human; 1:1000; loading ...; fig s1b
Cell Signaling Technology MSH6 antibody (Cell Signaling, D60G2) was used in western blot knockout validation on human samples at 1:1000 (fig s1b). Nat Commun (2018) ncbi
domestic rabbit monoclonal (D60G2)
  • western blot; human; fig s1
In order to analyze the divergent interactions with UNG2 and HLTF DNA repair proteins by HIV-1 and HIV-2, Cell Signaling Technology MSH6 antibody (Cell Signaling, 5424) was used in western blot on human samples (fig s1). Proc Natl Acad Sci U S A (2016) ncbi
BD Biosciences
mouse monoclonal (44/MSH6)
  • immunohistochemistry - paraffin section; human; loading ...; tbl 2
In order to determine the prognostic impact of parameters in peritoneal carcinomatosis from colorectal cancer, BD Biosciences MSH6 antibody (BD Transduction Laboratories, 44/MSH6) was used in immunohistochemistry - paraffin section on human samples (tbl 2). Am J Surg (2017) ncbi
mouse monoclonal (44/MSH6)
  • western blot knockout validation; mouse; 1:1000; fig 4
BD Biosciences MSH6 antibody (BD Biosciences, 610918) was used in western blot knockout validation on mouse samples at 1:1000 (fig 4). PLoS Genet (2016) ncbi
mouse monoclonal (44/MSH6)
  • immunohistochemistry; human; 1:800; fig s4b
In order to discuss mechanisms involved in the resistance of androgen receptor-targeted therapies, BD Biosciences MSH6 antibody (BD Biosciences, 610919) was used in immunohistochemistry on human samples at 1:800 (fig s4b). Nat Med (2016) ncbi
mouse monoclonal (44/MSH6)
  • immunohistochemistry; human; 1:100; loading ...
BD Biosciences MSH6 antibody (BD Pharmingen, 44) was used in immunohistochemistry on human samples at 1:100. JAMA Oncol (2016) ncbi
mouse monoclonal (44/MSH6)
  • western blot; mouse; 1:2500; loading ...; fig 4a
In order to study the role of Pms2 ATPase domain in male fertility, BD Biosciences MSH6 antibody (BD Biosciences, 610918) was used in western blot on mouse samples at 1:2500 (fig 4a). DNA Repair (Amst) (2016) ncbi
mouse monoclonal (44/MSH6)
  • immunohistochemistry; human; 1:200
BD Biosciences MSH6 antibody (BD Transduction Laboratories, 44/MSH6) was used in immunohistochemistry on human samples at 1:200. Virchows Arch (2015) ncbi
mouse monoclonal (44/MSH6)
  • immunohistochemistry - paraffin section; human
BD Biosciences MSH6 antibody (BD Pharmingen, 610919) was used in immunohistochemistry - paraffin section on human samples . Cancer Genet (2014) ncbi
mouse monoclonal (44/MSH6)
  • immunohistochemistry; human; 1:100; fig 1
In order to identify and characterize BRAF mutation from patients with metanephric adenomas, BD Biosciences MSH6 antibody (BD Biosciences, 44/MSH6) was used in immunohistochemistry on human samples at 1:100 (fig 1). Cancer Genet (2013) ncbi
mouse monoclonal (44/MSH6)
  • immunocytochemistry; human
  • western blot; human
BD Biosciences MSH6 antibody (BD Bioscience, 610919) was used in immunocytochemistry on human samples and in western blot on human samples . PLoS ONE (2013) ncbi
Articles Reviewed
  1. Shao W, Wang C, Wang L, Xiao F, Xiao D, Yang H, et al. A Hereditable Mutation of MSH2 Gene Associated with Lynch Syndrome in a Five Generation Chinese Family. Cancer Manag Res. 2020;12:1469-1482 pubmed publisher
  2. Rübben A, Wahl R, Eggermann T, Dahl E, Ortiz Brüchle N, Cacchi C. Mutation analysis of multiple pilomatricomas in a patient with myotonic dystrophy type 1 suggests a DM1-associated hypermutation phenotype. PLoS ONE. 2020;15:e0230003 pubmed publisher
  3. Wang J, Liu Y, Liu Y, Zheng S, Wang X, Zhao J, et al. Time-resolved protein activation by proximal decaging in living systems. Nature. 2019;569:509-513 pubmed publisher
  4. Zou X, Owusu M, Harris R, Jackson S, Loizou J, Nik Zainal S. Validating the concept of mutational signatures with isogenic cell models. Nat Commun. 2018;9:1744 pubmed publisher
  5. Massalou D, Benizri E, Chevallier A, Duranton Tanneur V, Pedeutour F, Benchimol D, et al. Peritoneal carcinomatosis of colorectal cancer: novel clinical and molecular outcomes. Am J Surg. 2017;213:377-387 pubmed publisher
  6. Zhao X, Lokanga R, Allette K, Gazy I, Wu D, Usdin K. A MutS?-Dependent Contribution of MutS? to Repeat Expansions in Fragile X Premutation Mice?. PLoS Genet. 2016;12:e1006190 pubmed publisher
  7. Hrecka K, Hao C, Shun M, Kaur S, Swanson S, Florens L, et al. HIV-1 and HIV-2 exhibit divergent interactions with HLTF and UNG2 DNA repair proteins. Proc Natl Acad Sci U S A. 2016;113:E3921-30 pubmed publisher
  8. Park J, Powell A, Roxburgh C, Horgan P, McMillan D, Edwards J. Mismatch repair status in patients with primary operable colorectal cancer: associations with the local and systemic tumour environment. Br J Cancer. 2016;114:562-70 pubmed publisher
  9. Beltran H, Prandi D, Mosquera J, Benelli M, Puca L, Cyrta J, et al. Divergent clonal evolution of castration-resistant neuroendocrine prostate cancer. Nat Med. 2016;22:298-305 pubmed publisher
  10. Taieb J, Zaanan A, Le Malicot K, Julie C, Blons H, Mineur L, et al. Prognostic Effect of BRAF and KRAS Mutations in Patients With Stage III Colon Cancer Treated With Leucovorin, Fluorouracil, and Oxaliplatin With or Without Cetuximab: A Post Hoc Analysis of the PETACC-8 Trial. JAMA Oncol. 2016;2:643-653 pubmed publisher
  11. Fischer J, Dudley S, Miller A, Liskay R. An intact Pms2 ATPase domain is not essential for male fertility. DNA Repair (Amst). 2016;39:46-51 pubmed publisher
  12. Vanoli A, Argenti F, Vinci A, La Rosa S, Viglio A, Riboni R, et al. Hepatoid carcinoma of the pancreas with lymphoid stroma: first description of the clinical, morphological, immunohistochemical, and molecular characteristics of an unusual pancreatic carcinoma. Virchows Arch. 2015;467:237-45 pubmed publisher
  13. Vilar E, Mork M, Cuddy A, Borràs E, Bannon S, Taggart M, et al. Role of microsatellite instability-low as a diagnostic biomarker of Lynch syndrome in colorectal cancer. Cancer Genet. 2014;207:495-502 pubmed publisher
  14. Gargalionis A, Korkolopoulou P, Farmaki E, Piperi C, Dalagiorgou G, Adamopoulos C, et al. Polycystin-1 and polycystin-2 are involved in the acquisition of aggressive phenotypes in colorectal cancer. Int J Cancer. 2015;136:1515-27 pubmed publisher
  15. Baiocchi G, Portolani N, Vermi W, Baronchelli C, Gheza F, Zogno C, et al. Lynch syndrome from a surgeon perspective: retrospective study of clinical impact of mismatch repair protein expression analysis in colorectal cancer patients less than 50 years old. BMC Surg. 2014;14:9 pubmed publisher
  16. Dadone B, Ambrosetti D, Carpentier X, Duranton Tanneur V, Burel Vandenbos F, Amiel J, et al. A renal metanephric adenoma showing both a 2p16e24 deletion and BRAF V600E mutation: a synergistic role for a tumor suppressor gene on chromosome 2p and BRAF activation?. Cancer Genet. 2013;206:347-52 pubmed
  17. Gupte M, Tuck A, Sharma V, Williams K. Major differences between tumor and normal human cell fates after exposure to chemotherapeutic monofunctional alkylator. PLoS ONE. 2013;8:e74071 pubmed publisher
  18. Gatalica Z, Lilleberg S, Monzon F, Koul M, Bridge J, Knezetic J, et al. Renal medullary carcinomas: histopathologic phenotype associated with diverse genotypes. Hum Pathol. 2011;42:1979-88 pubmed publisher
  19. Cossio S, Koehler Santos P, Pessini S, Mónego H, Edelweiss M, Meurer L, et al. Clinical and histomolecular endometrial tumor characterization of patients at-risk for Lynch syndrome in South of Brazil. Fam Cancer. 2010;9:131-9 pubmed publisher
  20. Arabi H, Guan H, Kumar S, Cote M, Bandyopadhyay S, Bryant C, et al. Impact of microsatellite instability (MSI) on survival in high grade endometrial carcinoma. Gynecol Oncol. 2009;113:153-8 pubmed publisher
  21. Mylona E, Zarogiannos A, Nomikos A, Giannopoulou I, Nikolaou I, Zervas A, et al. Prognostic value of microsatellite instability determined by immunohistochemical staining of hMSH2 and hMSH6 in urothelial carcinoma of the bladder. APMIS. 2008;116:59-65 pubmed publisher