This is a Validated Antibody Database (VAD) review about human MRPL12, based on 4 published articles (read how Labome selects the articles), using MRPL12 antibody in all methods. It is aimed to help Labome visitors find the most suited MRPL12 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
MRPL12 synonym: 5c5-2; L12mt; MRP-L31/34; MRPL7; MRPL7/L12; RPML12; 39S ribosomal protein L12, mitochondrial; MRP-L12; mitochondrial large ribosomal subunit protein bL12m

Proteintech Group
rabbit polyclonal
  • western blot; rat; 1:3000; loading ...
In order to investigate 2-methylcitrate-induced brain toxicity, Proteintech Group MRPL12 antibody (Proteintech, 14795-1-AP) was used in western blot on rat samples at 1:3000. Mol Genet Metab (2016) ncbi
rabbit polyclonal
  • western blot; mouse; fig 1
  • western blot; human; fig 3
In order to determine the requirement of mitochondrial ribosomal protein L12 for POLRMT stability and exists as two forms generated by alternative proteolysis during import, Proteintech Group MRPL12 antibody (Protein Tech, 14795-1-AP) was used in western blot on mouse samples (fig 1) and in western blot on human samples (fig 3). J Biol Chem (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (397.1)
  • western blot; mouse; fig 8f
Santa Cruz Biotechnology MRPL12 antibody (santa cruz, 397.1) was used in western blot on mouse samples (fig 8f). Front Endocrinol (Lausanne) (2015) ncbi
MilliporeSigma
rabbit polyclonal
  • western blot; human; fig 3g
MilliporeSigma MRPL12 antibody (sigma, HPA022853) was used in western blot on human samples (fig 3g). Nucleic Acids Res (2018) ncbi
Articles Reviewed
  1. Maiti P, Kim H, Tu Y, Barrientos A. Human GTPBP10 is required for mitoribosome maturation. Nucleic Acids Res. 2018;46:11423-11437 pubmed publisher
  2. Cudré Cung H, Zavadakova P, Do Vale Pereira S, Remacle N, Henry H, Ivanisevic J, et al. Ammonium accumulation is a primary effect of 2-methylcitrate exposure in an in vitro model for brain damage in methylmalonic aciduria. Mol Genet Metab. 2016;119:57-67 pubmed publisher
  3. Martin B, Chadwick W, Janssens J, Premont R, Schmalzigaug R, Becker K, et al. GIT2 Acts as a Systems-Level Coordinator of Neurometabolic Activity and Pathophysiological Aging. Front Endocrinol (Lausanne). 2015;6:191 pubmed publisher
  4. Nouws J, Goswami A, Bestwick M, McCann B, Surovtseva Y, Shadel G. Mitochondrial Ribosomal Protein L12 Is Required for POLRMT Stability and Exists as Two Forms Generated by Alternative Proteolysis during Import. J Biol Chem. 2016;291:989-97 pubmed publisher