This is a Validated Antibody Database (VAD) review about human MRP2, based on 29 published articles (read how Labome selects the articles), using MRP2 antibody in all methods. It is aimed to help Labome visitors find the most suited MRP2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
MRP2 synonym: ABC30; CMOAT; DJS; MRP2; cMRP

Abcam
mouse monoclonal (M2 III-6)
  • immunocytochemistry; human; 1:200; loading ...; fig 6s1d
Abcam MRP2 antibody (Abcam, ab3373) was used in immunocytochemistry on human samples at 1:200 (fig 6s1d). elife (2019) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; brown rat; 1:100; fig 2c
  • western blot; brown rat; 1:100; fig 2b
In order to develop a method to increase the intestinal transport of octreotide, Abcam MRP2 antibody (Abcam, ab203397) was used in immunohistochemistry - frozen section on brown rat samples at 1:100 (fig 2c) and in western blot on brown rat samples at 1:100 (fig 2b). Exp Ther Med (2016) ncbi
mouse monoclonal (M2 III-6)
  • immunocytochemistry; human; loading ...; fig 1a
Abcam MRP2 antibody (Abcam, ab3373) was used in immunocytochemistry on human samples (fig 1a). Alcohol Clin Exp Res (2016) ncbi
mouse monoclonal (M2 III-6)
  • immunohistochemistry; human; 1:200; loading ...; fig 2a
Abcam MRP2 antibody (Abcam, 3373) was used in immunohistochemistry on human samples at 1:200 (fig 2a). Sci Rep (2016) ncbi
mouse monoclonal (M2 III-6)
  • immunocytochemistry; human; 1:100; fig 2
In order to utilize the model system of primary human hepatocyte spheroids for drug-induced liver injury, disease, and liver function, Abcam MRP2 antibody (Abcam, ab3373) was used in immunocytochemistry on human samples at 1:100 (fig 2). Sci Rep (2016) ncbi
mouse monoclonal (M2 III-6)
  • western blot; human; 1:100; fig 3
Abcam MRP2 antibody (Abcam, ab3373) was used in western blot on human samples at 1:100 (fig 3). Exp Ther Med (2015) ncbi
mouse monoclonal (M2 III-6)
  • flow cytometry; human; 1:20; fig 1b
Abcam MRP2 antibody (Abcam, M2III-6) was used in flow cytometry on human samples at 1:20 (fig 1b). Curr Cancer Drug Targets (2016) ncbi
mouse monoclonal (M2 III-6)
  • immunocytochemistry; human; 1:50; loading ...; fig 4a
Abcam MRP2 antibody (abcam, ab3373) was used in immunocytochemistry on human samples at 1:50 (fig 4a). Sci Rep (2015) ncbi
mouse monoclonal (M2 III-6)
  • western blot; human; 1:100; fig s1
  • western blot; mouse; fig s1
In order to analyze multidrug resistant human cancer cells and autocrime cytokine/JAK/STAT-signaling induces kynurenin synthesis, Abcam MRP2 antibody (Abcam, ab3373) was used in western blot on human samples at 1:100 (fig s1) and in western blot on mouse samples (fig s1). PLoS ONE (2015) ncbi
mouse monoclonal (M2 III-6)
  • immunohistochemistry - frozen section; human; 1:50; loading ...; fig 2
In order to compare tricellulin expression in normal and cirrhotic liver with that of primary hepatic neoplasms, Abcam MRP2 antibody (Abcam, M2III-6) was used in immunohistochemistry - frozen section on human samples at 1:50 (fig 2). Pathol Oncol Res (2014) ncbi
mouse monoclonal (M2 III-6)
  • western blot; human
Abcam MRP2 antibody (Abcam, ab3373) was used in western blot on human samples . Biochim Biophys Acta (2014) ncbi
mouse monoclonal (M2 III-6)
  • immunohistochemistry - paraffin section; human
Abcam MRP2 antibody (Abcam, AB3373) was used in immunohistochemistry - paraffin section on human samples . Arch Toxicol (2014) ncbi
mouse monoclonal (M2 III-6)
  • immunocytochemistry; human; 1:100
In order to evaluate a culture method for the maturation of induced pluripotent stem cell derived hepatocytes, Abcam MRP2 antibody (Abcam, ab3373) was used in immunocytochemistry on human samples at 1:100. PLoS ONE (2014) ncbi
Enzo Life Sciences
mouse monoclonal (M2I-4)
  • immunocytochemistry; human; loading ...; fig 3a
Enzo Life Sciences MRP2 antibody (Alexis Biochemicals, M2-I-4) was used in immunocytochemistry on human samples (fig 3a). Hepatology (2017) ncbi
mouse monoclonal (M2III-6)
  • western blot; human; fig 7a
Enzo Life Sciences MRP2 antibody (Enzo Life Sciences, M2III-6) was used in western blot on human samples (fig 7a). Toxicology (2016) ncbi
mouse monoclonal (M2I-4)
  • immunohistochemistry - frozen section; human; 1:25; loading ...; fig 6
Enzo Life Sciences MRP2 antibody (Enzo Life Sciences, ALX-801-015-C250) was used in immunohistochemistry - frozen section on human samples at 1:25 (fig 6). Sci Rep (2016) ncbi
mouse monoclonal (M2I-4)
  • western blot; human; loading ...; fig 2b
Enzo Life Sciences MRP2 antibody (Enzo, ALX-801-015) was used in western blot on human samples (fig 2b). Drug Metab Dispos (2016) ncbi
mouse monoclonal (M2III-6)
  • western blot; human
Enzo Life Sciences MRP2 antibody (Enzo Life Sciences, M2III-6) was used in western blot on human samples . Pharm Res (2015) ncbi
mouse monoclonal (M2III-6)
  • western blot; brown rat; loading ...
Enzo Life Sciences MRP2 antibody (Alexis Biochemicals, M2III- 6) was used in western blot on brown rat samples . Arch Toxicol (2016) ncbi
mouse monoclonal (M2III-6)
  • western blot; human; fig 1
Enzo Life Sciences MRP2 antibody (Enzo Life Sciences, M2III-6) was used in western blot on human samples (fig 1). PLoS ONE (2015) ncbi
mouse monoclonal (M2III-5)
  • western blot; human
In order to describe the mechanisms and circumstances surrounding the choleretic activity of boldine, Enzo Life Sciences MRP2 antibody (Alexis, ALX 801-037) was used in western blot on human samples . Toxicol Appl Pharmacol (2015) ncbi
mouse monoclonal (M2III-5)
  • western blot; mouse
Enzo Life Sciences MRP2 antibody (Enzo Life Sciences, M2III-5) was used in western blot on mouse samples . Pharm Res (2013) ncbi
mouse monoclonal (M2III-6)
  • western blot; human
Enzo Life Sciences MRP2 antibody (Enzo Life Sciences, M2III-6) was used in western blot on human samples . PLoS Negl Trop Dis (2012) ncbi
mouse monoclonal (M2III-5)
  • western blot; brown rat
Enzo Life Sciences MRP2 antibody (Alexis Axxora, M2III5) was used in western blot on brown rat samples . Biochem Pharmacol (2012) ncbi
mouse monoclonal (M2III-6)
  • immunocytochemistry; brown rat
  • western blot; brown rat
Enzo Life Sciences MRP2 antibody (Alexis Axxora, M2III6) was used in immunocytochemistry on brown rat samples and in western blot on brown rat samples . Biochem Pharmacol (2012) ncbi
mouse monoclonal (M2III-6)
  • immunocytochemistry; brown rat
  • western blot; brown rat
Enzo Life Sciences MRP2 antibody (Enzo Life Sciences, M2III-6) was used in immunocytochemistry on brown rat samples and in western blot on brown rat samples . Drug Metab Dispos (2011) ncbi
mouse monoclonal (M2III-6)
  • western blot; human; 1:500
Enzo Life Sciences MRP2 antibody (Alexis, M2III-6) was used in western blot on human samples at 1:500. Mol Pharmacol (2011) ncbi
Invitrogen
mouse monoclonal (M2 III-6)
  • immunocytochemistry; human; fig s1c
In order to determine how hepatitis C virus activates a neuregulin-driven circuit to modify surface expression of growth factor receptors of the ErbB family, Invitrogen MRP2 antibody (Thermo Fisher Scientific, MA1-26536) was used in immunocytochemistry on human samples (fig s1c). PLoS ONE (2016) ncbi
EMD Millipore
mouse monoclonal (M2 I-4)
  • western blot; human
EMD Millipore MRP2 antibody (Millipore, MAB4148) was used in western blot on human samples . Toxicol Lett (2013) ncbi
mouse monoclonal (M2 III-6)
  • western blot; human; 1:50
EMD Millipore MRP2 antibody (Millipore Bioscience, M2 III-6) was used in western blot on human samples at 1:50. Drug Metab Dispos (2011) ncbi
Articles Reviewed
  1. Katsuda T, Matsuzaki J, Yamaguchi T, Yamada Y, Prieto Vila M, Hosaka K, et al. Generation of human hepatic progenitor cells with regenerative and metabolic capacities from primary hepatocytes. elife. 2019;8: pubmed publisher
  2. Sun X, Duan Z, Liu Z, Tang S, Li Y, He S, et al. Inhibition of P-glycoprotein, multidrug resistance-associated protein 2 and cytochrome P450 3A4 improves the oral absorption of octreotide in rats with portal hypertension. Exp Ther Med. 2016;12:3716-3722 pubmed publisher
  3. Delaunay J, Bruneau A, Hoffmann B, Durand Schneider A, Barbu V, Jacquemin E, et al. Functional defect of variants in the adenosine triphosphate-binding sites of ABCB4 and their rescue by the cystic fibrosis transmembrane conductance regulator potentiator, ivacaftor (VX-770). Hepatology. 2017;65:560-570 pubmed publisher
  4. Casey C, Bhat G, Holzapfel M, Petrosyan A. Study of Ethanol-Induced Golgi Disorganization Reveals the Potential Mechanism of Alcohol-Impaired N-Glycosylation. Alcohol Clin Exp Res. 2016;40:2573-2590 pubmed publisher
  5. Sayyed K, Vee M, Abdel Razzak Z, Jouan E, Stieger B, Denizot C, et al. Alteration of human hepatic drug transporter activity and expression by cigarette smoke condensate. Toxicology. 2016;363-364:58-71 pubmed publisher
  6. Sharanek A, Burban A, Burbank M, Le Guevel R, Li R, Guillouzo A, et al. Rho-kinase/myosin light chain kinase pathway plays a key role in the impairment of bile canaliculi dynamics induced by cholestatic drugs. Sci Rep. 2016;6:24709 pubmed publisher
  7. Bell C, Hendriks D, Moro S, Ellis E, Walsh J, Renblom A, et al. Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease. Sci Rep. 2016;6:25187 pubmed publisher
  8. Dröge C, Schaal H, Engelmann G, Wenning D, Haussinger D, Kubitz R. Exon-skipping and mRNA decay in human liver tissue: molecular consequences of pathogenic bile salt export pump mutations. Sci Rep. 2016;6:24827 pubmed publisher
  9. Csandl M, Conseil G, Cole S. Cysteinyl Leukotriene Receptor 1/2 Antagonists Nonselectively Modulate Organic Anion Transport by Multidrug Resistance Proteins (MRP1-4). Drug Metab Dispos. 2016;44:857-66 pubmed publisher
  10. Stindt S, Cebula P, Albrecht U, Keitel V, Schulte Am Esch J, Knoefel W, et al. Hepatitis C Virus Activates a Neuregulin-Driven Circuit to Modify Surface Expression of Growth Factor Receptors of the ErbB Family. PLoS ONE. 2016;11:e0148711 pubmed publisher
  11. Liu X, Yue X, Chen S, Chen J, Li R. Significance of the expression of MRP1 and MRP2 in peripheral blood mononuclear cells of children with intractable epilepsy. Exp Ther Med. 2015;10:1784-1788 pubmed
  12. Fanelli M, Hattinger C, Vella S, Tavanti E, Michelacci F, Gudeman B, et al. Targeting ABCB1 and ABCC1 with their Specific Inhibitor CBT-1® can Overcome Drug Resistance in Osteosarcoma. Curr Cancer Drug Targets. 2016;16:261-74 pubmed
  13. Lou Y, Kanninen L, Kaehr B, Townson J, Niklander J, Harjumäki R, et al. Silica bioreplication preserves three-dimensional spheroid structures of human pluripotent stem cells and HepG2 cells. Sci Rep. 2015;5:13635 pubmed publisher
  14. Bernd A, Ott M, Ishikawa H, Schroten H, Schwerk C, Fricker G. Characterization of efflux transport proteins of the human choroid plexus papilloma cell line HIBCPP, a functional in vitro model of the blood-cerebrospinal fluid barrier. Pharm Res. 2015;32:2973-82 pubmed publisher
  15. Campia I, Buondonno I, Castella B, Rolando B, Kopecka J, Gazzano E, et al. An Autocrine Cytokine/JAK/STAT-Signaling Induces Kynurenine Synthesis in Multidrug Resistant Human Cancer Cells. PLoS ONE. 2015;10:e0126159 pubmed publisher
  16. Barosso I, Zucchetti A, Miszczuk G, Boaglio A, Taborda D, Roma M, et al. EGFR participates downstream of ERα in estradiol-17β-D-glucuronide-induced impairment of Abcc2 function in isolated rat hepatocyte couplets. Arch Toxicol. 2016;90:891-903 pubmed publisher
  17. Rigalli J, Ciriaci N, Arias A, Ceballos M, Villanueva S, Luquita M, et al. Regulation of multidrug resistance proteins by genistein in a hepatocarcinoma cell line: impact on sorafenib cytotoxicity. PLoS ONE. 2015;10:e0119502 pubmed publisher
  18. Cermanova J, Kadova Z, Zagorova M, Hroch M, Tomsik P, Nachtigal P, et al. Boldine enhances bile production in rats via osmotic and farnesoid X receptor dependent mechanisms. Toxicol Appl Pharmacol. 2015;285:12-22 pubmed publisher
  19. Somorácz A, Korompay A, Törzsök P, Patonai A, Erdélyi Belle B, Lotz G, et al. Tricellulin expression and its prognostic significance in primary liver carcinomas. Pathol Oncol Res. 2014;20:755-64 pubmed publisher
  20. Guo S, Yu Y, Zhang N, Cui Y, Zhai L, Li H, et al. Higher level of plasma bioactive molecule sphingosine 1-phosphate in women is associated with estrogen. Biochim Biophys Acta. 2014;1841:836-46 pubmed publisher
  21. Ramaiahgari S, den Braver M, Herpers B, Terpstra V, Commandeur J, van de Water B, et al. A 3D in vitro model of differentiated HepG2 cell spheroids with improved liver-like properties for repeated dose high-throughput toxicity studies. Arch Toxicol. 2014;88:1083-95 pubmed publisher
  22. Gieseck R, Hannan N, Bort R, Hanley N, Drake R, Cameron G, et al. Maturation of induced pluripotent stem cell derived hepatocytes by 3D-culture. PLoS ONE. 2014;9:e86372 pubmed publisher
  23. Huuskonen P, Myllynen P, Storvik M, Pasanen M. The effects of aflatoxin B1 on transporters and steroid metabolizing enzymes in JEG-3 cells. Toxicol Lett. 2013;218:200-6 pubmed publisher
  24. Aleksunes L, Xu J, Lin E, Wen X, Goedken M, Slitt A. Pregnancy represses induction of efflux transporters in livers of type I diabetic mice. Pharm Res. 2013;30:2209-20 pubmed publisher
  25. Rigalli J, Perdomo V, Luquita M, Villanueva S, Arias A, Theile D, et al. Regulation of biotransformation systems and ABC transporters by benznidazole in HepG2 cells: involvement of pregnane X-receptor. PLoS Negl Trop Dis. 2012;6:e1951 pubmed publisher
  26. Rosales R, Monte M, Blazquez A, Briz O, Marin J. ABCC2 is involved in the hepatocyte perinuclear barrier for small organic compounds. Biochem Pharmacol. 2012;84:1651-9 pubmed publisher
  27. Tchaparian E, Houghton J, Uyeda C, Grillo M, Jin L. Effect of culture time on the basal expression levels of drug transporters in sandwich-cultured primary rat hepatocytes. Drug Metab Dispos. 2011;39:2387-94 pubmed publisher
  28. Haenisch S, Laechelt S, Bruckmueller H, Werk A, Noack A, Bruhn O, et al. Down-regulation of ATP-binding cassette C2 protein expression in HepG2 cells after rifampicin treatment is mediated by microRNA-379. Mol Pharmacol. 2011;80:314-20 pubmed publisher
  29. Mason C, Buhimschi I, Buhimschi C, Dong Y, Weiner C, Swaan P. ATP-binding cassette transporter expression in human placenta as a function of pregnancy condition. Drug Metab Dispos. 2011;39:1000-7 pubmed publisher