This is a Validated Antibody Database (VAD) review about human MR1, based on 4 published articles (read how Labome selects the articles), using MR1 antibody in all methods. It is aimed to help Labome visitors find the most suited MR1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
MR1 synonym: HLALS

BioLegend
mouse monoclonal (26.5)
  • blocking or activating experiments; human; fig 3a
BioLegend MR1 antibody (BioLegend, 361109) was used in blocking or activating experiments on human samples (fig 3a). Nat Immunol (2020) ncbi
mouse monoclonal (26.5)
  • blocking or activating experiments; human; loading ...; fig 1f
In order to detail MAIT cell responses to various microorganisms and cytokines, BioLegend MR1 antibody (BioLegend, 26.5) was used in blocking or activating experiments on human samples (fig 1f). Proc Natl Acad Sci U S A (2017) ncbi
mouse monoclonal (26.5)
BioLegend MR1 antibody (Biolegend, 361102) was used . Nat Commun (2016) ncbi
Abnova
mouse monoclonal (5E9)
  • ELISA; human; fig s1
Abnova MR1 antibody (Abnova, H000003140-M03) was used in ELISA on human samples (fig s1). MAbs (2015) ncbi
Articles Reviewed
  1. Crowther M, Dolton G, Legut M, Caillaud M, Lloyd A, Attaf M, et al. Genome-wide CRISPR-Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1. Nat Immunol. 2020;21:178-185 pubmed publisher
  2. Dias J, Leeansyah E, Sandberg J. Multiple layers of heterogeneity and subset diversity in human MAIT cell responses to distinct microorganisms and to innate cytokines. Proc Natl Acad Sci U S A. 2017;114:E5434-E5443 pubmed publisher
  3. van Wilgenburg B, Scherwitzl I, Hutchinson E, Leng T, Kurioka A, Kulicke C, et al. MAIT cells are activated during human viral infections. Nat Commun. 2016;7:11653 pubmed publisher
  4. Nambiar J, Clarke A, Shim D, Mabon D, Tian C, Windloch K, et al. Potent neutralizing anti-CD1d antibody reduces lung cytokine release in primate asthma model. MAbs. 2015;7:638-50 pubmed publisher