This is a Validated Antibody Database (VAD) review about human MOK, based on 6 published articles (read how Labome selects the articles), using MOK antibody in all methods. It is aimed to help Labome visitors find the most suited MOK antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
MOK synonym: RAGE; RAGE-1; RAGE1; STK30; MAPK/MAK/MRK overlapping kinase; renal cell carcinoma antigen; renal tumor antigen 1

R&D Systems
rat monoclonal (697023)
  • blocking or activating experiments; mouse; loading ...; fig 2e
R&D Systems MOK antibody (R&D Systems, MAB11795) was used in blocking or activating experiments on mouse samples (fig 2e). Nat Commun (2018) ncbi
goat polyclonal
  • blocking or activating experiments; mouse
R&D Systems MOK antibody (R&D systems, AF1179) was used in blocking or activating experiments on mouse samples . Biomed Res Int (2015) ncbi
goat polyclonal
  • blocking or activating experiments; human; 5 ug/ml
In order to investigate the effects of cell death and its products on intestinal epithelial cells with a focus on inflammatory bowel disease, R&D Systems MOK antibody (R&D Systems, AF1145) was used in blocking or activating experiments on human samples at 5 ug/ml. Am J Pathol (2015) ncbi
goat polyclonal
  • western blot; mouse
R&D Systems MOK antibody (R and D, AF1179) was used in western blot on mouse samples . J Lipid Res (2013) ncbi
goat polyclonal
  • blocking or activating experiments; mouse; 20 ug/ml
In order to identify the mechanism for the cardiomyocyte death induced by advanced oxidation protein products, R&D Systems MOK antibody (R & D Systems, AF1179) was used in blocking or activating experiments on mouse samples at 20 ug/ml. Free Radic Biol Med (2013) ncbi
Abcam
rabbit polyclonal
  • immunocytochemistry; mouse; fig 6a
  • western blot; mouse; fig 6e
In order to characterize the innate immunity responses to TDP-43 aggregates, Abcam MOK antibody (Abcam, ab135623) was used in immunocytochemistry on mouse samples (fig 6a) and in western blot on mouse samples (fig 6e). FASEB J (2017) ncbi
Articles Reviewed
  1. Wolf D, Anto Michel N, Blankenbach H, Wiedemann A, Buscher K, Hohmann J, et al. A ligand-specific blockade of the integrin Mac-1 selectively targets pathologic inflammation while maintaining protective host-defense. Nat Commun. 2018;9:525 pubmed publisher
  2. Leal Lasarte M, Franco J, Labrador Garrido A, Pozo D, Roodveldt C. Extracellular TDP-43 aggregates target MAPK/MAK/MRK overlapping kinase (MOK) and trigger caspase-3/IL-18 signaling in microglia. FASEB J. 2017;31:2797-2816 pubmed publisher
  3. Jin X, Yao T, Zhou Z, Zhu J, Zhang S, Hu W, et al. Advanced Glycation End Products Enhance Macrophages Polarization into M1 Phenotype through Activating RAGE/NF-κB Pathway. Biomed Res Int. 2015;2015:732450 pubmed publisher
  4. Scarpa M, Kessler S, Sadler T, West G, Homer C, McDonald C, et al. The epithelial danger signal IL-1α is a potent activator of fibroblasts and reactivator of intestinal inflammation. Am J Pathol. 2015;185:1624-37 pubmed publisher
  5. Quade Lyssy P, Kanarek A, Baiersdörfer M, Postina R, Kojro E. Statins stimulate the production of a soluble form of the receptor for advanced glycation end products. J Lipid Res. 2013;54:3052-61 pubmed publisher
  6. Valente A, Yoshida T, Clark R, Delafontaine P, Siebenlist U, Chandrasekar B. Advanced oxidation protein products induce cardiomyocyte death via Nox2/Rac1/superoxide-dependent TRAF3IP2/JNK signaling. Free Radic Biol Med. 2013;60:125-35 pubmed publisher